Articles tagged with Laboratories
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A new study reveals that chromatin proteins defective in RTT, CdLS, and ATR-X syndromes are associated with each other and regulate imprinted genes. This cooperation may explain similarities between the associated human syndromes.
Researchers have developed a new material that can capture heat-trapping carbon dioxide emissions using a synthetic DNA-like crystal. The discovery could lead to cleaner energy and potentially create materials that convert carbon dioxide into fuel.
The University of California, Riverside's new Stem Cell Core Facility will enable faster breakthroughs in stem cell research, targeting diseases such as osteoporosis and diabetes. The facility is equipped with the first-in-country Nikon BioStation CT technology, expected to provide valuable data for attacking degenerative diseases.
Researchers developed SCGPSim, a simulation infrastructure that uses parallel processing and CUDA programming model to speed up SystemC-based hardware models. This could significantly reduce the time it takes to bring products to market, improving the efficiency of semiconductor electronics industry.
Researchers have produced high-quality graphene on a large scale, overcoming two major barriers to scaling up the technology. The material's electrical characteristics can now be measured with unprecedented precision, paving the way for widespread adoption in high-speed electronics.
Researchers developed a mathematical methodology to reduce biologic variation in laboratory results, improving the sensitivity of detecting physiologic changes. By using multiple paired sets of patient data, they found a substantial decrease in the difference necessary to achieve a given confidence interval.
A new protocol for fluorescence in situ hybridization allows phylogenetic identification of microorganisms in environmental samples. Meanwhile, a dual-color ELISPOT assay enables simultaneous detection of IL-2 and IFN-γ secreting T cells, promising to monitor immune responses to certain infectious agents.
Researchers at Thomas Jefferson University have successfully engineered tobacco plants to produce more oil in their leaves, which can be used as a sustainable biofuel. The modified plants yielded up to 20-fold more oil than normal tobacco plant leaves, paving the way for a new energy source.
A sudden increase in antibiotic-resistant E. coli strains is spreading globally, posing a significant threat to public health. Researchers warn that the misuse of powerful antibiotics may lead to the development of even more resistant strains, rendering current treatments ineffective.
EMBO has awarded 50,000 euro grants to 5 scientists to establish research groups in the Czech Republic, Poland, and Portugal. The grantees will join the prestigious network of EMBO Young Investigators and integrate into the European scientific community.
The ASCB annual meeting featured the winners of 'Celldance 2009,' a film and still image contest recognizing scientifically important and visually engaging cell content. This year's top prize winners included Angela Stathopoulos for her video '2PEF Imaging Captures Gastrulation in Fly Embryos' and Aswati Subramanian for her scanning el...
Researchers found that first-line ART can be delivered safely without routine biochemistry and haematology monitoring, but CD4-cell count monitoring has a small benefit in disease progression and mortality. The trial suggests that monitoring should start from the second year of ART to guide the switch to second-line treatment.
Researchers developed new computerized surveillance algorithms using algebraic theories to improve object and target detection. The technology reduces manual review time by 99%, enhancing image analysis capabilities.
New live cell imaging techniques allow researchers to visualize dynamic changes in living cells, providing insights into biological processes. The application of computational image processing is also crucial for extracting meaningful data from this type of imaging.
Researchers at NIST and Naval Research Laboratory create a technique to selectively implant atoms in crystals, enabling study of electrical and magnetic properties on an atomic scale. This development is crucial for spintronics, electronic devices that utilize electron spin instead of charge for storing information.
A three-year study of six large Arctic river ecosystems reveals predictable temporal patterns among bacterial communities, suggesting they could be used to monitor climate change. The findings show that these communities shift synchronously over time, correlating with seasonal shifts in hydrology and biogeochemistry.
A recent UCLA study found that blindness causes structural changes in the brain, leading to compensatory growth in non-visual areas. This adaptation enables individuals with visual impairments to develop enhanced skills in other senses.
The project aims to create a communication network capable of supporting various military platforms and devices, while ensuring security and trustworthiness.
A recent study found that female water striders prefer non-aggressive males over highly sexually aggressive ones when it comes to mating. In contrast, groups of low-key male water striders mated with more females than did groups of highly aggressive males.
The EMBO Young Investigators Programme identifies top European young life scientists, offering academic and financial help to set up independent research labs. The selected 17 young group leaders work in nine countries, with an average age of 36 and four women, and will benefit from various activities including mentorship and networking.
The article features laboratory methods for high-throughput genotyping, including single-nucleotide polymorphism (SNP) genotyping and next-generation sequencing. The tandem affinity purification (TAP) procedure is also presented as a method for protein purification.
A new study by Yale University researchers reveals that learning to talk alters the way we hear speech sounds, suggesting a two-way street between sensory and motor processing. This finding has major implications for improving speech disorders such as those caused by stroke and Parkinson's disease.
The BU School of Medicine's CityLab program has received a five-year, $1.3 million grant from the National Institutes of Health (NIH) to enhance its clinical research curriculum with hands-on laboratory experiments and computer-generated simulations.
Researchers at Air Force Office of Scientific Research have successfully established high-data-rate optical links over long distances using adaptive optics to overcome atmospheric distortions. The next step is to conduct flight tests at increased altitudes to demonstrate air-to-ground quantum communications capabilities.
A University of Exeter study found exercise decreases attention to smoking-related images, with participants spending 11% less time looking at these images after exercising. This suggests exercise can help reduce interest in and salience of smoking cues, making it easier for smokers to quit.
Researchers at UC Riverside successfully created metal-free 'abnormal N-heterocyclic carbenes', which are highly reactive molecules used to make catalysts. These carbenes are stable and can be used in numerous catalytic chemical reactions, greatly benefiting industry.
Researchers at the University of York have identified an enzyme called XplA that can break down royal demolition explosive (RDX) in the soil. The discovery provides significant insights into biological function and could lead to more efficient cleanup methods for RDX pollution.
Researchers will analyze fine and ultrafine particles in air pollution using the $400,000 AirCARE 2 laboratory. The study aims to understand how pollutant particles exacerbate pre-existing respiratory and cardiovascular disease.
Willard Boyle shares Nobel Prize for co-invention of charged-couple device (CCD) with George E. Smith and Charles K. Kao. The CCD is a semiconductor circuit capable of sensing light and images, key technology behind digital photography.
A three-year research study is examining how freshwater marsh ecosystems react to global environmental change. The study will focus on the formation of marshes and their sensitivity to changes in water levels, biodiversity, and sediment deposition, with results aimed at preventing unintended destruction and restoring degraded marshes.
A team of researchers has developed a scintillating bolometer, a device that detects light and heat produced by dark matter particles. The device was tested at the Canfranc Underground Laboratory in Spain and performed excellently, proving its viability as a detector for dark matter.
Researchers conclude that controlled-release pills and capsules prone to dose dumping due to alcohol consumption require human testing. Formulations may pose significant overdose risks even after lab tests indicate faster release rates.
The Regenstrief Institute has developed technologies to enable rapid, secure bi-directional exchange of health information between clinical sources and public health organizations. This allows for efficient sharing of information on emerging risks and outbreak detection.
Researcher Rohit Trivedi conducts crystal growth experiments on the International Space Station using a mini lab called DECLIC. The goal is to understand how materials form crystals and how variations affect crystallization patterns, which govern material properties.
The MSD Wellcome Trust Hilleman Laboratories aims to develop new vaccines to prevent diseases affecting low-income countries. The not-for-profit joint venture will work on optimizing existing vaccines and developing new ones, with the goal of increasing vaccine impact in resource-limited settings.
The study reveals that Fbox proteins alternate between attaching to and being kicked off CRL1 by competing protein CAND1. This process is stabilized by the phosphorylated substrate N8, allowing for efficient degradation of aberrant proteins. The research highlights the importance of the proline residue in Fbox protein-CRL1 interaction.
The study found that the pathogen's genome is unusually large and has a unique structure, enabling rapid evolution of genes involved in plant infection. The 'two-speed' genomic strategy allows different parts of the genome to evolve at different rates, potentially making it harder for plants to resist infection.
Researchers found that pathogenic E. coli strains can survive modern food processing methods and exploit different food sources than laboratory strains. They demonstrated differences in growth characteristics, antimicrobial resistance, and reaction to environmental stresses.
Dr. Paul Flecknell, a renowned expert in laboratory animal pain management, has been recognized with the 2009 Charles River Laboratories' Excellence in Refinement Award. His work focuses on developing methods of pain assessment and alleviation for various species.
The article presents optimized ChIP protocol for mammalian cells, while recombineering methods are used to construct targeting vectors for conditional knockout mice. These techniques provide efficient and precise genetic modifications.
Research shows that the brain uses the same neural networks to process both familiar and newly learned words, with no clear differences in function. New definitions are learned even faster than new names, indicating a possible link between meaning retention and brain activation patterns.
A Chinese study establishes a multifaceted barrier-focused intervention program to increase colonoscopy attendance among nonadherent high-risk populations for colorectal cancer screening. The program significantly increased attendance rates, especially among those with objective barriers.
Researchers at RIT and UB are developing real-time information products to help emergency responders during disasters. The lab will focus on technology, policy, and business-development to create potential business opportunities for industry.
The Systems Biology Graphical Notation (SBGN) is a new visual language for graphically representing biological information, aiming to make complex models accurate, efficient, and easy to understand. Developed by researchers worldwide, SBGN will benefit systems biologists working on various biochemical processes.
Researchers from Turkey performed a non-radiation ERCP procedure on six pregnant patients with choledocholithiasis and one patient with biliary fistula, showing no complications. Laboratory and ultrasonographic follow-up confirmed successful treatment and stone extraction without radiation exposure.
A multi-laboratory study has updated ASTM guidelines for measuring nanoparticle size, incorporating statistically evaluated data from 26 laboratories. The results provide a valuable benchmark for labs measuring nanoparticles, which is crucial in biotech applications where nanoparticle size affects cell response.
A new molecule known as soluble VEGFR-2 has been identified that selectively blocks lymphatic vessel growth but not blood vessel growth. This breakthrough could lead to targeted treatments for diseases such as lymphedema, transplant rejection, and tumor metastasis.
The NRL's XFC UAS has successfully demonstrated a flight endurance milestone of over six hours, paving the way for long-endurance Intelligence, Surveillance and Reconnaissance (ISR) missions. The fuel cell-powered system greatly extends payload capacity and endurance compared to traditional battery-powered UAS.
Researchers from Cold Spring Harbor Laboratory present a method for targeting hematopoietic stem cells using engineered lentiviral vectors. An alternative approach using DNA transposons offers a safer and effective way for non-viral gene transfer.
Researchers Dr. Margaret Palmer and Dr. Solange Filoso caution that market-based environmental restoration programs lack scientific certainty to ensure ecosystem health improvements.
A comprehensive book Shifting Sands examines Maryland's Coastal Bays ecosystem, detailing its six subwatersheds, history, and ecology. The study synthesizes decades of research to provide a holistic understanding of the region's fragile lagoons.
Montana State University is launching a pilot program to test the effectiveness of web-based engineering laboratory courses. With an $148,000 NSF grant, students will be able to control real laboratory equipment from home computers, simulating in-person lab experiences.
Researchers from Northwestern University have successfully grown a woman's immature egg cells, contained in a tiny sac called a follicle, to a healthy and nearly mature egg in the laboratory. This breakthrough could provide a new fertility option for women whose cancer treatments destroy their ability to reproduce.
Dr. Keri Smith has received a Career Development Award from the National Hemophilia Foundation to develop a therapy for people with Hemophilia A. Her approach involves altering chemical signals produced by T cells that trigger immune responses, making individuals more receptive to replacement Factor VIII.
A new metagenomic approach quantifies microorganisms in environmental or medical samples, while a method for adhesive micropatterning offers a simple technique for generating patterns. These methods provide insights into microbial populations and cellular behaviors.
The first comprehensive global assessment reveals accelerating losses of seagrasses, threatening the health and sustainability of coastal ecosystems. Seagrasses disappear at rates similar to coral reefs and tropical rainforests, with a loss of 110 square-kilometers per year since 1980.
Researchers found a coffee extract can prevent malodorous bacteria from causing bad breath, contradicting the common assumption that coffee leads to bad breath. The team tested different brands of coffee and found some components that inhibit bacterial odor production.
The study found that hydrofluorocarbons (HFCs) will become an increasingly larger factor in future climate warming if business-as-usual trends continue. By 2050, HFC emissions could contribute 7-12% to climate change, exceeding CO2's current contribution.
Researchers are developing effective treatment strategies and animal model systems to study the effects of explosive blast-induced traumatic brain injury. Current research aims to recreate battlefield injuries in laboratory settings to better understand head injuries sustained during combat.
The Pew Charitable Trusts has named 10 promising young scientists as Pew Latin American Fellows in the Biomedical Sciences. The fellows will receive $60,000 in salary support and an additional $35,000 to purchase essential equipment upon returning to their home countries.