Articles tagged with Laboratories
A new analysis of 50 years of changes in freshwater inputs to the Arctic Ocean and North Atlantic reveals that freshwater increases from Arctic Ocean sources are highly linked to a fresher North Atlantic. The study, published in Science, suggests that changes in climate and atmospheric dynamics may be driving this trend.
African sleeping sickness parasite Trypanosoma brucei evolves an unusual chromosomal structure to diversify its VSG genes and evade human immune response. This adaptation enables the parasite to change protein expression rapidly, allowing it to persist in a host population.
The latest issue of Cold Spring Harbor Protocols highlights over 50 new RNA interference methods for researchers to study gene functions in model organisms. These protocols provide detailed guidelines for handling embryonic stem cells, visualizing programmed cell death, and preparing cells for microscopic imaging.
Carnegie Institution's Marilyn Fogel receives Fulbright grant for astrobiology research, tracing phenomena and exploring life on Mars. The grant supports her work with the AMASE team in Svalbard, a Norwegian island similar to Martian geology.
Researchers from Jackson Laboratory found that high BMI is not directly associated with a high percentage of fat, suggesting the need for more refined measurements to distinguish between large body mass and true obesity. The study's results have implications for understanding the complex interplay of genetic factors in health disorders.
Researchers have successfully created sperm in a laboratory using embryonic stem cells, demonstrating their viability in producing viable offspring. The study opens up new avenues for investigating mechanisms involved in sperm production and developing new treatment strategies for infertility.
Researchers found that laboratory animal workers who handled more than 50 rats per day had a two-fold reduction in the risk of developing work-related chest symptoms. This suggests that exposure to laboratory animals can lead to natural immunity, as indicated by high IgG4-IgE antibody ratios.
A survey of UK laboratories showed a 83% increase in lab test requests from primary care between 2000 and 2004. Two strategies developed by Dr. Bernie Croal reduced unnecessary test requests by 10-22% in Scottish primary care practices. These interventions are feasible within most laboratory settings.
Biologists observed sea slug navigation, feeding, mating, and egg-laying behavior, shedding light on its complex nervous system. The study confirms that many wild behaviors are similar to laboratory observations, providing new insights into sensory systems and neural controls.
A new experimental vaccine has been shown to protect nonhuman primates against Marburg virus infection, even when administered after exposure. The study found that all treated monkeys survived for at least 80 days, while controls succumbed to the disease within 12 days.
HHMI's Janelia Farm Research Campus aims to promote high-risk, high-reward research by providing internal funding and a flexible environment. The campus will feature small research groups, active bench scientists, and excellent support facilities.
Researchers found cuttlefish can detect contrast differences of at least 15%, suggesting they use intensity matching for camouflage. The study's findings shed light on the complex visual processing of these cephalopods, an ideal model for studying camouflage.
David Walt's HHMI-funded program aims to infuse undergraduate and K-12 education with scientific discovery, tackling real-world problems and promoting interdisciplinary approaches. The initiative seeks to boost the flow of students into scientific research and careers.
The Jackson center aims to understand how genes interact to develop healthy individuals or lead to diseases, leveraging the power of the mouse model. Collaborators will use computational approaches to identify clusters of genes associated with complex diseases, shedding light on their evolution and causes.
Researchers at Columbia University's Mailman School of Public Health have developed a rapid and highly sensitive diagnostic test for pathogens responsible for disease outbreaks. The new test, known as MassTag PCR, can simultaneously identify multiple agents and reduce the time needed for differential diagnosis.
The CLS prototype has successfully produced its first X-ray beam, demonstrating the feasibility of compact synchrotrons. This breakthrough offers new opportunities for researchers to access high-quality, tunable x-ray beams in university and industrial labs.
The HYbrid Coordinate Ocean Model (HYCOM) provides long-range weather prediction, enhances ocean current understanding, and supports real-time maritime operations. This innovative tool enables accurate forecasts and tracking of pollution, algal blooms, and oil spills.
A study conducted by the NIH and NINDS evaluated patients treated with natalizumab for relapsing-remitting MS and found no new cases of PML. However, the researchers caution that the long-term risk associated with natalizumab treatment is unknown.
The new mobile lab expands the diagnostic laboratory's capacity to respond to animal disease outbreaks, enabling quick expansion of testing capabilities. The trailer is equipped with biosafety level 3 standards and can process blood and tissue samples within 24-48 hours.
Researchers used virtual-reality displays to show that humans can't accurately judge size and distance when motion is present. Instead, they prefer a stable representation of the world independent of head and eye movements.
Researchers found high levels of selenium in contaminated toads and their offspring, leading to developmental abnormalities such as structural malformations and abnormal swimming. The study highlights the importance of maternal transfer in contaminant exposure for amphibians.
Scientists study stardust in labs to understand element formation and stellar evolution. The analysis of isotopic compositions provides clues about nuclear and chemical processes in stars.
The University of Houston is collaborating with the US Navy to develop nanomagnetic biosensors for detecting biological warfare agents and land mines. The program aims to create high-sensitivity techniques for improving land mine detection.
Ahmet Yildiz developed a new technique for fluorescence imaging that allowed him to identify the 'walking mechanism' used by protein motors in living cells. He applied this technique to measure how Myosin V, a biomolecular motor involved in intracellular transport, moves.
A team led by FSU physicist Sam Tabor has discovered a novel form of radioactive decay in which two protons are ejected simultaneously from a silver atom. This unexpected finding expands knowledge of nuclear physics and has implications for astrophysics and the production of elements on Earth.
Researchers have developed hybrid antibodies from chimpanzees and humans that effectively inhibited the spread of vaccinia and variola viruses in test tube experiments. In mice infected with vaccinia virus, the hybrid antibodies proved more effective than anti-vaccinia immune globulin when given two days after virus exposure.
In eukaryotic cells, RINGO/Spy controls transcription and translation through protein-protein interactions. It inhibits the activity of the translation initiation factor eIF4E, leading to reduced protein synthesis.
A comprehensive update of E. coli K-12 genes has been published, providing a centralized resource for the scientific community. The project, led by MBL scientists, aims to improve understanding of gene function and accelerate laboratory work.
A team of bio-archaeologists confirms the existence of human activity in northern Europe dating back approximately 700,000 years. The findings were made using a newly-refined technique of amino acid analysis and published in Nature.
Researchers are developing intelligent systems to monitor seniors' daily lives and detect changes in health. The ORCATECH center is creating technologies for in-home monitoring of mobility, cognition, and medication management.
The grant will support two graduate and five undergraduate students at Prairie View A&M University in Texas, as well as a postdoctoral position at North Carolina A&T University. The magnet lab will provide hands-on research experience for minority researchers, aiming to increase their participation in extreme conditions research.
The Genetics & Public Policy Center urges the government to issue proposed regulations for a genetic testing specialty, citing concerns over the lack of oversight in the industry. The center argues that a genetic testing specialty is achievable with key quality requirements such as analytic and clinical validity.
The APL contributed significantly to the success of the Flight Test Mission (FTM) 04-2, a live event that verified the Aegis BMD 3.0 weapon system's performance against a more difficult threat.
Researchers at NIST have developed a method to improve the efficiency of water chillers in large commercial buildings. By adding small amounts of oil additives to refrigerants, they claim to increase cooling capacity similar to a heat pump.
This article explores how diseases, drugs, and chemicals affected famous artists such as Michelangelo, Edvard Munch, Ivar Arosenius, and Vincent van Gogh. Clinical laboratory analysis is providing new insights into their creative achievements.
A new test developed by a McMaster virologist can identify infected individuals early in an outbreak, limiting the spread of virus in the community. The test will be available for evaluation by hospital-based laboratories and reference laboratories by early December.
Agnès Vignery, an expert in bone development, will conduct collaborative research at Pfizer's Global Research and Development. Her lab has developed a new technology to induce bone formation for fracture prevention, which is being refined in rodents for human translation.
Researchers have found that high-voltage sparks can produce x-ray bursts, similar to those observed during lightning. This discovery opens the door for studying the poorly understood phenomenon of runaway breakdown in a lab setting.
Researchers have discovered that lipids, specifically phosphatidylinositol transfer protein-α, are regulated during axon growth and play a critical role in nervous system development. Blocking this lipid can prevent nerves from developing arm-like extensions, leading to neuron death and motor neuron degeneration.
The American Society for Clinical Pathology is providing laboratory training and quality improvement programs for diagnosis and monitoring of HIV/AIDS patients in resource-limited countries. The program aims to improve the effectiveness of HIV diagnostic, care, and treatment services and interventions.
Researchers found that college students accurately report their alcohol consumption, contradicting previous laboratory studies suggesting they underreport. This suggests that the drinking problem remains significant, but data collection methods may need to be reevaluated.
The NMSU Physical Science Laboratory designed and fielded a countermeasure device in under three months to combat IEDs, providing increased survivability for warfighters. The signal-jamming equipment is being used by the US Army, Marines, and Navy Explosive Ordinance Disposal unit.
The Open Network Laboratory (ONL) provides a platform for researchers to develop, test, and demonstrate improvements in networking environments. With its high-performance routers and extensibility features, the ONL enables users to create new communication services and evaluate innovative ideas in a realistic setting.
Researchers in The Netherlands found a positive trend in rheumatoid arthritis disease activity over the last decade, coinciding with more aggressive treatment strategies. The study showed that patients diagnosed with RA within the last ten years had less severe disease activity and a more favorable course of their disease.
Duke University's integration of electronic laboratory notebooks improves student engagement and reduces cheating, but has limitations due to software challenges. The adoption of electronic notebooks is not widespread among universities and businesses.
The ERCC proposes developing consistent, well-characterized RNA samples to validate gene expression assays. These external RNA controls will help ensure comparable results across microarray and QRT-PCR systems.
The US Army's Gamma Phage Assay has been approved by the FDA for human use within the Laboratory Response Network (LRN), enabling early detection of anthrax bioterrorism threats. This test, developed with CDC support, is a classical bacteriological method that uses a virus to identify B. anthracis.
SINTEL aims to provide automated, real-time situational information for ship crews, including threat assessment and decision aids. The lab will test and analyze threat scenarios in the NY Harbor environment using a combination of E/O and IR sensor modeling systems.
A study using tree-ring data reveals that severe droughts and low-flow conditions in one basin are unlikely to be offset by abundant streamflow in another. The research covers waterways from Arizona, Colorado, New Mexico, Utah, and Wyoming, spanning nearly 800 years.
Researchers at Ames Laboratory developed a method called dynamic multiple equilibrium gradients (DMEG) that enables hyperselective separation and concentration of specific analytes. This advancement allows for the detection of smallest substance traces, including estrogen-derived conjugates and DNA adducts in human fluid samples, poten...
A study by Rutgers University researchers found that combining TPA, a compound from the croton plant, with all-trans retinoic acid (ATRA) effectively inhibits growth of pancreatic cancer cells. The combination also showed increased apoptosis and reduced mitosis in tumors.
A new study found that females prefer males with higher ocelli density but also those with shorter tails, suggesting they value the visual perception of a dense cluster. This preference is driven by both ocelli density and male displaying activity, providing peahens with information about male health.
Using RoboLase, Australian scientists successfully performed sub-cellular surgery on a laser microscope system in California, demonstrating the potential for remote medical procedures. The technology enabled researchers to collaborate without traveling to a single laboratory site, paving the way for increased global scientific collabor...
Researchers discover KDI tri-peptide can block glutamate's damage in degenerative brain diseases, potentially leading to paralysis reversal and nerve regeneration. Human clinical trials expected to begin next year, with no toxic side effects seen so far.
Gwen Hoben, a M.D.-Ph.D. student at Rice University, has won the highly competitive Hertz fellowship to pursue her research in tissue engineering. The award provides funding for tuition and fees, as well as a $28,000 stipend, giving her more flexibility to explore scientific questions.
The National Institute of Standards and Technology (NIST) is establishing a program to accredit voting system test labs, which will be part of the National Voluntary Laboratory Accreditation Program (NVLAP). NVLAP accreditation is a prerequisite for laboratories to be considered as Voting System Test and Certification Authorities (VSTC...
Researchers at Ames Lab investigate solid fuels mimicking methane, ideal for hydrogen production and efficient energy storage. They use mechanochemical processing and nanostructuring to create recharged materials.
Researchers have developed a new vaccine that is 100 percent effective in protecting monkeys from infection with deadly viruses Ebola and Marburg. The vaccine targets dendritic cells, which are the same cells attacked by these viruses.
The Rockefeller University and Memorial Sloan Kettering Cancer Center are collaborating on stem cell research to understand the biology of stem cells. Researchers are working together to identify cancer stem cells and develop cell-based therapeutic strategies for diseases like Parkinson's.
A research team has identified a genetic defect that weakens blood vessels in the brain, making infants vulnerable to cerebral hemorrhage. The discovery may lead to new strategies for disease prevention, such as reducing stress during birth.