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New diagnostic method finds aggressive tumors

Researchers have developed a new genomic method, CUTseq, that can assess the amount and type of copy number alterations in tumors, helping identify highly heterogeneous and aggressive cancers. The technique is cheaper than existing technologies and can be applied to multiple biopsies or small tissue sections.

SourceKarolinska Institutet·JournalNature Communications·DateOct 18, 2019

Ultrafast particle interactions could help make quantum information devices feasible

Researchers detected energy transfer from excited electrons to the crystal lattice on the femtosecond timescale, enabling the development of materials that retain energy for longer periods. This study contributes to the retardation of decoherence and the creation of quantum information devices such as optical switches.

How status sticks to genes

Research on rhesus macaques reveals that past social status has a lasting impact on gene expression, with low-ranking females showing signs of 'molecular memory' even after improving their social standing. The study sheds light on how stressful experiences can shape long-term health outcomes.

SourceDuke University·JournalProceedings of the National Academy of Sciences·DateOct 15, 2019

How to make biocatalysts immortal

A research team from Bochum and Marseille has developed a self-defence mechanism in biocatalysts that shields them from oxygen, extending their service life up to 22,000 years. The new design uses tiny molecular spheres to create an extremely thin protective film that maintains efficiency.

SourceRuhr-University Bochum·JournalJournal of the American Chemical Society·DateOct 9, 2019

Using plasma to find Alzheimer's

Tymora Analytical Operations is developing a plasma-based approach for early detection of Alzheimer's disease. The company aims to analyze exosome proteins and phosphoproteins in plasma samples to identify biomarkers linked to the disease.

Fruit flies live longer with combination drug treatment

A triple drug combination of lithium, trametinib, and rapamycin has been shown to extend the lifespan of fruit flies by 48%, a significant increase compared to previous studies. The treatment targets different cellular processes and may have potential benefits for preventing age-related diseases in humans.

SourceUniversity College London·JournalProceedings of the National Academy of Sciences·DateSep 30, 2019

Jackdaws learn from each other about 'dangerous' humans

Researchers at the University of Exeter found that jackdaws can learn to identify dangerous people by hearing a warning call, and this knowledge helps them avoid humans who pose a threat. The birds that heard the warning call returned to their nests more quickly when seeing the human again, indicating they had learned to recognize danger.

SourceUniversity of Exeter·JournalRoyal Society Open Science·DateSep 24, 2019

Employee contract structures in startups can be determining factors of success

A new study by Evgeny Kagan and colleagues found that incentive clauses in contracts work best for high-performing team members, while those who may not be high performers do not benefit from incentives. The researchers suggest delaying contracting to learn about team member personalities and adjusting contract structures accordingly.

Ageing research to accelerate with experimental validation in AI-powered drug discovery

Researchers have developed an AI-powered drug discovery tool that validates novel drug candidates in just 46 days, significantly reducing the traditional 2-3 year timeline. The foundation aims to motivate researchers to harness AI's potential in longevity research and encourage larger developers to adopt AI-powered programs.

SourceBiogerontology Research Foundation·JournalNature Biotechnology·DateSep 4, 2019

Start-ups must be aware of star employee pitfalls

Research from Washington State University reveals that hiring star employees alongside founders can stall product innovation efforts due to conflicting influences. The study advises start-ups to establish clear chain of command, hire experienced start-up employees, and adapt to change as the organization evolves.

SourceWashington State University·JournalStrategic Entrepreneurship Journal·DateAug 28, 2019

High diversity of harvestmen in Atlantic Rainforest and ancient geological events

The study found that ancient geological events, such as mountain range uplift and river formation, drove the emergence of new species of harvestmen in the southern portion of the Atlantic Rainforest. This discovery challenges the assumption that climate fluctuations are the primary cause of high biodiversity in this biome.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalMolecular Phylogenetics and Evolution·DateAug 22, 2019