The 44th AChemS meeting investigates how COVID-19 affects olfactory function, leading to significant symptomology and quality of life impacts. Researchers will discuss recent findings on chemosensory testing and COVID-19, as well as the relationship between smell and depression.
A cross-racial study of 1.87 million US veterans found significant differences in dementia incidence across five racial groups, with Hispanic and Black veterans at highest risk. Rates were significantly higher for Hispanics (99%) and Blacks (55%), while Asian veterans showed a 24% increase compared to whites.
Researchers found that wealth was associated with a 19 percentage point increase in survival rates from age 65 to 85, but smoking dominated other factors in shortening lifespan. The study suggests that avoiding smoking is crucial for living longer, regardless of wealth levels.
Researchers at The University of Toledo found that low-dose lithium acts as a powerful anti-aging agent in the kidneys by blocking GSK3-beta, an enzyme associated with cellular aging. Studies showed improved kidney function and reduced albuminuria in mice and psychiatric patients treated with lithium.
Matthias Mann, Director of Proteomics and Signal Transduction at Max Planck Institute, presents latest research on Single cell and Deep Visual Proteomics for precision medicine. The conference focuses on accelerating aging research and discovery, with top-level speakers sharing groundbreaking research.
A recent study suggests that many older adults with rheumatoid arthritis are not prescribed disease-modifying medications, despite guidelines calling for early and aggressive treatment. Only 45% of patients over 65 were prescribed these medications, highlighting the need to improve prescribing practices among primary care physicians.
A University of Otago study found altering an existing assessment tool could double the capture rate of elder abuse sufferers. By adding an 'unable to determine' category, tens of thousands of older New Zealanders may be identified as victims of abuse.
Dr. Tim R Peterson's research explores the molecular cause-and-effect between infectious disease and aging, identifying a shared biochemistry that drives senescent cell formation. The presentation highlights potential applications of FDA-approved drugs in developing novel senolytics.
Dr. Joris Deelen will present his latest research on identifying and functional characterizing genetic variants linked to human longevity. The work aims to understand the efficacy of previously identified biomarkers of aging in clinical studies, using omics-based approaches such as metabolomics.
The rate of older adults treated for substance abuse increased sharply from 2000 to 2017, with a notable rise in cannabis and cocaine use. This trend is attributed to decreasing stigma around substance abuse, allowing more older adults to seek help through self-referrals.
A study published in International Journal of Geriatric Psychiatry found that antidepressants were associated with a lower risk of suicide among residents aged 75+, who had a significantly increased risk if taking sleep medication or having a history of self-harm. The research highlights the need for early recognition and quality care ...
Dr. Fabio Demontis will present his research on Myokine-based interventions to contrast muscle and brain aging at the 9th Aging Research & Drug Discovery Meeting 2022. His lab aims to understand how communication between skeletal muscle and the brain influences proteostasis as we age.
Dudley Lamming, a renowned expert in aging research, will present his latest findings on how specific dietary amino acids regulate health and longevity. His research aims to understand the molecular mechanisms underlying aging and potential interventions.
A study by Norwegian University of Science and Technology finds that people over 60 account for nearly a third of global greenhouse gas emissions. This is due to their consumption habits, including higher energy usage and housing expenses, which are influenced by their wealth and aging population.
A new Brazilian database of whole-genome sequences brings diverse genetic information to international databases, shedding light on the genetics of aging and disease in Brazil's elderly population. The study identified over 2 million novel genetic variants, providing insights into the health and well-being of older adults.
A study finds that extreme heat is associated with a significant increase in cardiovascular mortality, particularly among men and non-Hispanic Black adults. The researchers analyzed data from over 3,100 counties in the US and found that each additional day of extreme heat was linked to an average of 600-700 additional deaths per year.
Researchers from IRB Barcelona have discovered that damaged mitochondria accumulation triggers inflammatory processes leading to muscle atrophy. Correcting mitochondrial function through increased BNIP3 levels can mitigate inflammation and muscle loss, offering potential tools for promoting healthy ageing.
A new study found that excessive daytime napping among seniors is associated with an increased risk of developing dementia and Alzheimer's disease. After a diagnosis of mild cognitive impairment or Alzheimer's, daytime napping duration triples, suggesting that the brain's wake-promoting neurons may be affected by dementia pathology.
Global thought-leaders will share their insights into aging and its effects, with a focus on reducing age-associated morbidities and frailty. The conference aims to develop interventions that can slow down or reverse the aging process, benefiting everyone's health and lifespan.
A new study led by UC San Francisco reveals that 87% of seniors with dementia would stop at least one medication if their doctor said it was possible. Polypharmacy contributes to challenges with adherence and adverse interactions, but most patients are willing to reduce their medications.
Researchers at the Salk Institute successfully reversed aging signs in middle-aged and elderly mice using a cellular rejuvenation approach. The treatment, which involves reprogramming cells with four specific molecules, restored youthful epigenetic patterns and improved tissue function without increasing cancer risk.
A new study by Dartmouth's Geisel School of Medicine found higher mortality rates among older adults with cognitive impairment during the COVID-19 pandemic. The study showed a 24% increase in mortality for individuals with Alzheimer's disease and a 36% increase for nursing home residents with ADRD.
New Penn State research found that the maximum wet-bulb temperature for humans is lower than previously thought, at around 31°C in warm-humid environments. This finding has significant implications for planning and preparing for extreme heat events.
A large-scale study aims to understand how individual brains change over time, identifying factors that increase cognitive decline risk and those that confer resilience. The Adult Aging Brain Connectome study will follow 1,000 participants across a decade, collecting brain scans, blood samples, and demographic data.
Researchers found that daily life movement, including housework and self-care activities, significantly benefits cardiovascular health. Women with at least four hours of daily life movement had a 43% lower risk of cardiovascular disease, 62% lower risk of cardiovascular disease death.
A study by Washington State University found that social support can mitigate the risk of heart disease and death in older American Indians. Higher rates of depression symptoms, poor quality of life, and social isolation were linked to increased mortality, but instrumental social support reversed this effect.
A Finnish twin study found that individuals with lower education are more susceptible to the negative effects of cardiovascular risk factors on late-life cognition. The study suggests that higher education can act as a cognitive reserve, helping to mitigate dementia risk.
A new study reveals that social isolation and loneliness can increase cardiovascular disease risk by 8% and 5% respectively. Women who experience high levels of both social isolation and loneliness have a 13-27% increased risk of heart disease, compared to those with low levels.
Ovarian cancer death rates are predicted to decrease by 17% in the UK and 7% in EU countries in 2022. The main contributor is the long-term use of oral contraceptives, reducing the risk by 40%. Other factors include improved diagnosis, treatment, and advancements in treatments for other cancers.
A study found that racialized immigrants were less likely to report good health, with experiences of discrimination contributing to these disparities. Social isolation and lower socioeconomic status also increased the risk of poorer health.
A new study of Chinese older adults found that higher levels of social isolation are associated with having fewer teeth and losing teeth more quickly over time. Despite this, loneliness was not linked to the number of remaining teeth or tooth loss rate.
A study published in Diabetes Care found that walking regularly at greater intensity and taking more steps can lower the risk of developing Type 2 diabetes among adults aged 65 and older. For every 1,000 additional steps per day, the risk is reduced by 6%, with a 12% reduction possible if an average adult takes 2,000 more steps daily.
A new study found a 1,886% increase in opioid-related overdose deaths among U.S. adults aged 55 and older between 1999 and 2019. Contributing factors include ageism, social isolation, depression, and declining cognitive function.
Researchers at Penn State will investigate ways to stimulate muscle growth by increasing ribosome production. Their goal is to find molecular targets that can be used to promote muscle growth without exercise or drugs. This study aims to prevent muscle loss due to aging, cancer, and other chronic diseases.
A recent study published in Alzheimer's & Dementia found that regular exercise enhances the connections between neurons in older adults, maintaining healthy cognition. The research, led by Kaitlin Casaletto and William Honer, suggests that physical activity may help boost synaptic functioning and safeguard against dementia.
A new study by University of Waterloo researchers reveals that for-profit long-term care homes owned by private equity firms and large chains have the highest mortality rates during COVID-19. The study found a correlation between financialization of senior housing and lower quality care, with prioritizing profits over patient outcomes.
A new study has made an Alzheimer's disease biomarker test available to all Canadians, enabling doctors to accurately diagnose the disease even when mild symptoms are present. The test aims to improve care and support for individuals living with Alzheimer's disease and their families.
A new study reveals that extracellular vesicles deliver genetic instructions for the longevity protein Klotho to muscle cells, which declines with age. This finding suggests that EVs could be developed into novel therapies for healing damaged muscle tissue and improving functional recovery in older individuals.
A new study found that cognitive behavioral therapy (CBT-I) prevented major depression in older adults with insomnia, decreasing the likelihood of depression by over 50%. CBT-I was more effective than sleep education therapy in preventing depression and promoting sustained remission of insomnia.
A new index ranks US states based on their support for successful aging across five domains: productivity, security, equity, cohesion, and well-being. The study found that no single domain drives the results, and state policies play a significant role in adapting to an aging population.
A study of nearly 500,000 Medicare patients with long-term dialysis revealed COVID-19 risk factors and associated mortality rates. The research highlights the need for targeted interventions to protect vulnerable populations.
A new UCSF study shows that solo seniors with social support are less likely to need nursing home care. Older adults who said they could count on a friend or relative for assistance in the event of a health crisis reduced their risk of institutional care from 14.2% to 10.9%. The study found that many older adults can take care of thems...
Researchers found that levels of chitinase 3-like-1 increase with age and co-morbid diseases, augmenting SARS-CoV-2 infection. A therapeutic antibody blocks the induction of the ACE2 receptor, potentially paving the way for COVID-19 prevention and treatment.
A study found that younger B-cell non-Hodgkin lymphoma survivors are at a higher risk of developing age-related diseases, including renal failure, pneumonia, and nutritional deficiencies. The research suggests that aggressive treatment regimens may be the underlying factor contributing to this increased risk.
Researchers found that Alzheimer's disease develops by replicating aggregates in individual brain regions, rather than spreading them. The study used human data and PET scans to track the aggregation of tau protein, a key player in the disease.
A new study published in the International Journal of Nursing Studies found that home care patients who prefer a language other than English are more likely to be readmitted to hospital within 30 days. The study suggests that addressing language gaps is crucial for improving patient outcomes and reducing healthcare costs.
The project aims to address rising healthcare costs, health disparities, and expands digital health through advances in AI. It also trains students from different disciplines to develop and apply data science techniques.
Researchers create maps of senescence in heart and lung cells, comparing different types of senescent cells across the lifespan. The goal is to understand how senescent cells contribute to age-related diseases and develop therapies called senolytics.
Researchers identify key neurons and signaling pathway regulating female activity before ovulation. Discoveries could lead to new treatments for menopause that sidestep estrogen and reactivates the circuit with CRISPRa technology.
A study of nearly 179,000 veterans aged 65+ found that maximizing the dosage of an existing medication can lead to better adherence and lower blood pressure. Adding a new medication shows a slim advantage in some cases, but with risks associated with polypharmacy.
A new study led by UCSF indicates that depression in early adulthood can increase the risk of cognitive impairment and dementia. The research found that moderate or high depressive symptoms were associated with a 73% higher odds of cognitive impairment among older participants.
A new study published in PNAS suggests that China's declining birth rate and aging population may not negatively impact future prosperity. The researchers found that higher education levels among women can lead to increased labor force participation, potentially offsetting the negative effects of population aging.
Skeletal muscle secretes a molecule that regulates around 35% of liver functions, with the remaining basal functions independent of muscle activity. Ageing alters this communication, leading to non-optimal functions and accelerated ageing.
A study of over 2,000 European retirees found that internet usage after retirement is associated with better cognitive scores. Specifically, female retirees who regularly surfed the internet recalled more words on a word recall test compared to their non-internet-using counterparts.
Researchers found that aging workforces, characterized by a higher ratio of workers 56 and older to those ages 21-55, are associated with increased robot deployment in 60 countries. This study suggests that automation adoption is partly driven by labor shortages, particularly middle-aged labor needed for blue-collar work.
Researchers analyzed large datasets to find biomarkers that could help select immunotherapy treatment for older patients. The analysis suggests that factors such as mutational burden and immune checkpoint protein expression are associated with increased response to immunotherapies in older patients, despite lower general immunity.
Researchers found that seniors moving from low-mortality areas to high-mortality areas experience a significant decrease in life expectancy. On the other hand, urban areas on the East and West Coasts have positive effects on longevity for seniors, while Midwestern metro areas score well. The study also identified parts of the deep Sout...
Dr. Maria Carolina Florian will present her latest research on aging hematopoietic stem cells, challenging the concept that aging is an irreversible process. Her work aims to improve tissue homeostasis and regeneration by targeting epigenetic polarity and functionally rejuvenating aged HSCs.
A recent study by MPIDR researchers found that participating in the labor market until age 67 slows cognitive decline and protects against cognitive impairment. This effect holds regardless of gender or educational/occupational attainment, with a slowed rate of cognitive decline rather than improved function.
Researchers created Community ASAP to help locate missing people with dementia, engaging community citizens as volunteers. The app aims to address the lack of alerts for this population, which has a high risk of wandering and experiencing serious injury or death within 24 hours.