Articles tagged with Aging Populations
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A new Brazilian database of whole-genome sequences brings diverse genetic information to international databases, shedding light on the genetics of aging and disease in Brazil's elderly population. The study identified over 2 million novel genetic variants, providing insights into the health and well-being of older adults.
A study finds that extreme heat is associated with a significant increase in cardiovascular mortality, particularly among men and non-Hispanic Black adults. The researchers analyzed data from over 3,100 counties in the US and found that each additional day of extreme heat was linked to an average of 600-700 additional deaths per year.
Researchers from IRB Barcelona have discovered that damaged mitochondria accumulation triggers inflammatory processes leading to muscle atrophy. Correcting mitochondrial function through increased BNIP3 levels can mitigate inflammation and muscle loss, offering potential tools for promoting healthy ageing.
A new study found that excessive daytime napping among seniors is associated with an increased risk of developing dementia and Alzheimer's disease. After a diagnosis of mild cognitive impairment or Alzheimer's, daytime napping duration triples, suggesting that the brain's wake-promoting neurons may be affected by dementia pathology.
Global thought-leaders will share their insights into aging and its effects, with a focus on reducing age-associated morbidities and frailty. The conference aims to develop interventions that can slow down or reverse the aging process, benefiting everyone's health and lifespan.
A new study led by UC San Francisco reveals that 87% of seniors with dementia would stop at least one medication if their doctor said it was possible. Polypharmacy contributes to challenges with adherence and adverse interactions, but most patients are willing to reduce their medications.
Researchers at the Salk Institute successfully reversed aging signs in middle-aged and elderly mice using a cellular rejuvenation approach. The treatment, which involves reprogramming cells with four specific molecules, restored youthful epigenetic patterns and improved tissue function without increasing cancer risk.
A new study by Dartmouth's Geisel School of Medicine found higher mortality rates among older adults with cognitive impairment during the COVID-19 pandemic. The study showed a 24% increase in mortality for individuals with Alzheimer's disease and a 36% increase for nursing home residents with ADRD.
New Penn State research found that the maximum wet-bulb temperature for humans is lower than previously thought, at around 31°C in warm-humid environments. This finding has significant implications for planning and preparing for extreme heat events.
A large-scale study aims to understand how individual brains change over time, identifying factors that increase cognitive decline risk and those that confer resilience. The Adult Aging Brain Connectome study will follow 1,000 participants across a decade, collecting brain scans, blood samples, and demographic data.
Researchers found that daily life movement, including housework and self-care activities, significantly benefits cardiovascular health. Women with at least four hours of daily life movement had a 43% lower risk of cardiovascular disease, 62% lower risk of cardiovascular disease death.
A study by Washington State University found that social support can mitigate the risk of heart disease and death in older American Indians. Higher rates of depression symptoms, poor quality of life, and social isolation were linked to increased mortality, but instrumental social support reversed this effect.
A Finnish twin study found that individuals with lower education are more susceptible to the negative effects of cardiovascular risk factors on late-life cognition. The study suggests that higher education can act as a cognitive reserve, helping to mitigate dementia risk.
A new study reveals that social isolation and loneliness can increase cardiovascular disease risk by 8% and 5% respectively. Women who experience high levels of both social isolation and loneliness have a 13-27% increased risk of heart disease, compared to those with low levels.
Ovarian cancer death rates are predicted to decrease by 17% in the UK and 7% in EU countries in 2022. The main contributor is the long-term use of oral contraceptives, reducing the risk by 40%. Other factors include improved diagnosis, treatment, and advancements in treatments for other cancers.
A study found that racialized immigrants were less likely to report good health, with experiences of discrimination contributing to these disparities. Social isolation and lower socioeconomic status also increased the risk of poorer health.
A study published in Diabetes Care found that walking regularly at greater intensity and taking more steps can lower the risk of developing Type 2 diabetes among adults aged 65 and older. For every 1,000 additional steps per day, the risk is reduced by 6%, with a 12% reduction possible if an average adult takes 2,000 more steps daily.
A new study of Chinese older adults found that higher levels of social isolation are associated with having fewer teeth and losing teeth more quickly over time. Despite this, loneliness was not linked to the number of remaining teeth or tooth loss rate.
A new study found a 1,886% increase in opioid-related overdose deaths among U.S. adults aged 55 and older between 1999 and 2019. Contributing factors include ageism, social isolation, depression, and declining cognitive function.
Researchers at Penn State will investigate ways to stimulate muscle growth by increasing ribosome production. Their goal is to find molecular targets that can be used to promote muscle growth without exercise or drugs. This study aims to prevent muscle loss due to aging, cancer, and other chronic diseases.
A recent study published in Alzheimer's & Dementia found that regular exercise enhances the connections between neurons in older adults, maintaining healthy cognition. The research, led by Kaitlin Casaletto and William Honer, suggests that physical activity may help boost synaptic functioning and safeguard against dementia.
A new study by University of Waterloo researchers reveals that for-profit long-term care homes owned by private equity firms and large chains have the highest mortality rates during COVID-19. The study found a correlation between financialization of senior housing and lower quality care, with prioritizing profits over patient outcomes.
A new study has made an Alzheimer's disease biomarker test available to all Canadians, enabling doctors to accurately diagnose the disease even when mild symptoms are present. The test aims to improve care and support for individuals living with Alzheimer's disease and their families.
A new study reveals that extracellular vesicles deliver genetic instructions for the longevity protein Klotho to muscle cells, which declines with age. This finding suggests that EVs could be developed into novel therapies for healing damaged muscle tissue and improving functional recovery in older individuals.
A new study found that cognitive behavioral therapy (CBT-I) prevented major depression in older adults with insomnia, decreasing the likelihood of depression by over 50%. CBT-I was more effective than sleep education therapy in preventing depression and promoting sustained remission of insomnia.
A new index ranks US states based on their support for successful aging across five domains: productivity, security, equity, cohesion, and well-being. The study found that no single domain drives the results, and state policies play a significant role in adapting to an aging population.
A study of nearly 500,000 Medicare patients with long-term dialysis revealed COVID-19 risk factors and associated mortality rates. The research highlights the need for targeted interventions to protect vulnerable populations.
A new UCSF study shows that solo seniors with social support are less likely to need nursing home care. Older adults who said they could count on a friend or relative for assistance in the event of a health crisis reduced their risk of institutional care from 14.2% to 10.9%. The study found that many older adults can take care of thems...
Researchers found that levels of chitinase 3-like-1 increase with age and co-morbid diseases, augmenting SARS-CoV-2 infection. A therapeutic antibody blocks the induction of the ACE2 receptor, potentially paving the way for COVID-19 prevention and treatment.
A study found that younger B-cell non-Hodgkin lymphoma survivors are at a higher risk of developing age-related diseases, including renal failure, pneumonia, and nutritional deficiencies. The research suggests that aggressive treatment regimens may be the underlying factor contributing to this increased risk.
Researchers found that Alzheimer's disease develops by replicating aggregates in individual brain regions, rather than spreading them. The study used human data and PET scans to track the aggregation of tau protein, a key player in the disease.
A new study published in the International Journal of Nursing Studies found that home care patients who prefer a language other than English are more likely to be readmitted to hospital within 30 days. The study suggests that addressing language gaps is crucial for improving patient outcomes and reducing healthcare costs.
The project aims to address rising healthcare costs, health disparities, and expands digital health through advances in AI. It also trains students from different disciplines to develop and apply data science techniques.
Researchers create maps of senescence in heart and lung cells, comparing different types of senescent cells across the lifespan. The goal is to understand how senescent cells contribute to age-related diseases and develop therapies called senolytics.
Researchers identify key neurons and signaling pathway regulating female activity before ovulation. Discoveries could lead to new treatments for menopause that sidestep estrogen and reactivates the circuit with CRISPRa technology.
A study of nearly 179,000 veterans aged 65+ found that maximizing the dosage of an existing medication can lead to better adherence and lower blood pressure. Adding a new medication shows a slim advantage in some cases, but with risks associated with polypharmacy.
A new study led by UCSF indicates that depression in early adulthood can increase the risk of cognitive impairment and dementia. The research found that moderate or high depressive symptoms were associated with a 73% higher odds of cognitive impairment among older participants.
A new study published in PNAS suggests that China's declining birth rate and aging population may not negatively impact future prosperity. The researchers found that higher education levels among women can lead to increased labor force participation, potentially offsetting the negative effects of population aging.
Skeletal muscle secretes a molecule that regulates around 35% of liver functions, with the remaining basal functions independent of muscle activity. Ageing alters this communication, leading to non-optimal functions and accelerated ageing.
A study of over 2,000 European retirees found that internet usage after retirement is associated with better cognitive scores. Specifically, female retirees who regularly surfed the internet recalled more words on a word recall test compared to their non-internet-using counterparts.
Researchers found that aging workforces, characterized by a higher ratio of workers 56 and older to those ages 21-55, are associated with increased robot deployment in 60 countries. This study suggests that automation adoption is partly driven by labor shortages, particularly middle-aged labor needed for blue-collar work.
Researchers analyzed large datasets to find biomarkers that could help select immunotherapy treatment for older patients. The analysis suggests that factors such as mutational burden and immune checkpoint protein expression are associated with increased response to immunotherapies in older patients, despite lower general immunity.
Researchers found that seniors moving from low-mortality areas to high-mortality areas experience a significant decrease in life expectancy. On the other hand, urban areas on the East and West Coasts have positive effects on longevity for seniors, while Midwestern metro areas score well. The study also identified parts of the deep Sout...
Dr. Maria Carolina Florian will present her latest research on aging hematopoietic stem cells, challenging the concept that aging is an irreversible process. Her work aims to improve tissue homeostasis and regeneration by targeting epigenetic polarity and functionally rejuvenating aged HSCs.
A recent study by MPIDR researchers found that participating in the labor market until age 67 slows cognitive decline and protects against cognitive impairment. This effect holds regardless of gender or educational/occupational attainment, with a slowed rate of cognitive decline rather than improved function.
Researchers at the University of Pittsburgh School of Medicine have found that brain tissue inflammation is a key driver of Alzheimer's disease progression. By targeting neuroinflammation, they believe combination therapy could be more effective in reducing amyloid plaque formation and limiting tau fiber spread.
Dr. Brian Kennedy will discuss his latest research on the path to longer lifespan and healthspan, highlighting potential smooth or bumpy routes to achieving healthy longevity. The conference aims to bring together experts to share groundbreaking research and developments in aging and drug discovery.
Researchers created Community ASAP to help locate missing people with dementia, engaging community citizens as volunteers. The app aims to address the lack of alerts for this population, which has a high risk of wandering and experiencing serious injury or death within 24 hours.
Dr. Anne-Ulrike Trendelenburg will present research on targeting common pathways to treat age-related diseases, including sarcopenia and premature aging diseases. The conference brings together experts from academia and industry to discuss progress in the molecular, cellular and organismal basis of aging.
Researchers analyze impact of risk factors on heat-related mortality at different spatial scales, finding age, education, and socioeconomic status are key contributors. A localized approach is needed to address specific conditions at the city, region, and neighborhood levels.
Kai-Fu Lee will present his latest research on AI and its applications in healthcare at the 8th Aging Research & Drug Discovery Meeting. The conference aims to discuss the molecular, cellular, and organismal basis of aging and search for interventions.
Researchers found that states have implemented new autism-specific Medicaid programs, with the most common type being the 1915(c) waiver authority, providing home and community-based services. The study suggests that further replication of successful efforts is needed to improve access to services for individuals on the autism spectrum.
Dr. Sibylle Jäger will present a new research on a salicylic acid derivative that prevents oxidative damage in skin, exploring its potential as an intervention for aging. The conference aims to discuss the latest progress in understanding the molecular basis of aging and finding interventions.
VitaDAO, a decentralized intellectual property collective, is funding early-stage longevity drug development. The conference will discuss novel approaches to funding aging research, with experts sharing their latest groundbreaking research.
Dr. Nir Barzilai will present his latest research on neurotherapeutics from genetic-based discovery in centenarians, focusing on designing and delivering treatment for every disease. The conference aims to bridge clinical, academic, and commercial research to find practical solutions for extending healthy lifespan.
Dr. Anne Brunet will present her latest research on mechanisms of brain aging and rejuvenation, focusing on novel genes regulating longevity and neural stem cell aging. The conference aims to bridge clinical, academic, and commercial research to develop practical solutions for extending the healthy lifespan of everyone.
A Dartmouth research team led by Glyn Elwyn is testing interactive educational approaches to boost vaccine confidence among unvaccinated long-term care workers. The study aims to measure vaccine confidence, knowledge, and trust in the COVID-19 vaccines.
A new study reveals that people's feelings about their age are closely tied to their physical health and well-being. Subjective age discordance, the difference between how old one feels and wants to be, was found to be more pronounced in older adults but fluctuated more in younger adults.
The Gerontological Society of America's Journalists in Aging Fellows Program aims to educate journalists about issues in aging and disseminate information on new scientific findings. The fellowship program has supported over 700 news stories, equipping reporters with accurate fact-based coverage for diverse audiences.
Researchers found a significant association between estrogen receptor α PvuII polymorphisms and dementia in a Brazilian cohort. The study suggests that this polymorphism may contribute to the development of dementia, particularly in elderly populations.