Articles tagged with Aging Populations
A new study finds that having three or more children is negatively correlated with late-life cognition, with the effect strongest in Northern Europe. The researchers suggest that this may be due to financial stress and reduced social interaction, leading to potential cognitive deterioration.
Dr. Blagosklonny discusses the potential of combining rapamycin with other modalities to live long enough to benefit from future discoveries in cellular reprogramming. He emphasizes that Altos Labs needs to develop rapamycin-based drug combinations to achieve additional decades of life extension, potentially within 3-5 years.
A new study suggests that supplementing a diet with Ascidiacea, also known as sea squirts, reverses some main signs of aging in animal models. The researchers found that plasmalogens, vital to body processes, decrease with age and contribute to neurodegenerative diseases like Alzheimer's and Parkinson's.
A new study reveals that Asia and Africa have a similar aging burden to the West, with a Health-Adjusted Dependency Ratio (HADR) that indicates the impact of ill-health on dependency ratios. The HADR metric suggests that demographic age is not the only factor determining dependency, and that health levels play a significant role.
Scientists have discovered a master gene that programs ear hair cells into either outer or inner ones, enabling the development of these cells to restore hearing. This breakthrough could provide a previously unavailable tool to create specific hair cells and improve treatments for age-related hearing loss.
Scientists have found that transplanting faecal microbiota from young mice into old mice can reverse hallmarks of ageing in the gut, eyes, and brain. The study suggests that gut microbes play a role in regulating some of the detrimental effects of ageing, offering a potential solution in the form of gut microbe replacement therapy.
Canada's cancer rates are declining overall, but new cases and deaths are on the rise due to an aging population and growing numbers. Despite this, efforts in cancer prevention, screening, early detection, and treatment have led to improved survival rates for those diagnosed with cancer.
A new microsimulation model projects that the Japanese population will live longer and experience a decrease in years spent living with dementia. However, older women with less than a high school education are more likely to be affected by both dementia and frailty.
A new study found that wolves preferentially target adult moose with osteoarthritis, an age-related disease, over prime-aged adults. This selective predation helps maintain a balance in prey populations, reducing the incidence of diseases such as osteoarthritis.
The 44th AChemS meeting investigates how COVID-19 affects olfactory function, leading to significant symptomology and quality of life impacts. Researchers will discuss recent findings on chemosensory testing and COVID-19, as well as the relationship between smell and depression.
Dr. Jennifer Garrison will present her latest research on Reframing Health and Aging through the Lens of Reproductive Longevity at the 9th ARDD conference. Her lab studies inter-tissue communication in systemic aging and its impact on female reproductive decline.
Researchers at Einstein Aging Study are investigating how social forces contribute to inequalities in cognitive health, particularly among Black and Hispanic Americans. The new grant will enable the tracking of over 700 Bronx adults with mobile technology to measure cognition directly as they engage in everyday activities.
Dr. Kristen Fortney will present her research on data-informed drug discovery and clinical development for therapies targeting aging at the 9th Aging Research and Drug Discovery conference. The presentation aims to unlock opportunities to treat or prevent diseases of aging by targeting molecular pathways that impact healthy human aging.
A cross-racial study of 1.87 million US veterans found significant differences in dementia incidence across five racial groups, with Hispanic and Black veterans at highest risk. Rates were significantly higher for Hispanics (99%) and Blacks (55%), while Asian veterans showed a 24% increase compared to whites.
Researchers found that wealth was associated with a 19 percentage point increase in survival rates from age 65 to 85, but smoking dominated other factors in shortening lifespan. The study suggests that avoiding smoking is crucial for living longer, regardless of wealth levels.
Researchers at The University of Toledo found that low-dose lithium acts as a powerful anti-aging agent in the kidneys by blocking GSK3-beta, an enzyme associated with cellular aging. Studies showed improved kidney function and reduced albuminuria in mice and psychiatric patients treated with lithium.
Matthias Mann, Director of Proteomics and Signal Transduction at Max Planck Institute, presents latest research on Single cell and Deep Visual Proteomics for precision medicine. The conference focuses on accelerating aging research and discovery, with top-level speakers sharing groundbreaking research.
A recent study suggests that many older adults with rheumatoid arthritis are not prescribed disease-modifying medications, despite guidelines calling for early and aggressive treatment. Only 45% of patients over 65 were prescribed these medications, highlighting the need to improve prescribing practices among primary care physicians.
A University of Otago study found altering an existing assessment tool could double the capture rate of elder abuse sufferers. By adding an 'unable to determine' category, tens of thousands of older New Zealanders may be identified as victims of abuse.
Dr. Tim R Peterson's research explores the molecular cause-and-effect between infectious disease and aging, identifying a shared biochemistry that drives senescent cell formation. The presentation highlights potential applications of FDA-approved drugs in developing novel senolytics.
Dr. Joris Deelen will present his latest research on identifying and functional characterizing genetic variants linked to human longevity. The work aims to understand the efficacy of previously identified biomarkers of aging in clinical studies, using omics-based approaches such as metabolomics.
A study published in International Journal of Geriatric Psychiatry found that antidepressants were associated with a lower risk of suicide among residents aged 75+, who had a significantly increased risk if taking sleep medication or having a history of self-harm. The research highlights the need for early recognition and quality care ...
The rate of older adults treated for substance abuse increased sharply from 2000 to 2017, with a notable rise in cannabis and cocaine use. This trend is attributed to decreasing stigma around substance abuse, allowing more older adults to seek help through self-referrals.
Dr. Fabio Demontis will present his research on Myokine-based interventions to contrast muscle and brain aging at the 9th Aging Research & Drug Discovery Meeting 2022. His lab aims to understand how communication between skeletal muscle and the brain influences proteostasis as we age.
A study by Norwegian University of Science and Technology finds that people over 60 account for nearly a third of global greenhouse gas emissions. This is due to their consumption habits, including higher energy usage and housing expenses, which are influenced by their wealth and aging population.
A new Brazilian database of whole-genome sequences brings diverse genetic information to international databases, shedding light on the genetics of aging and disease in Brazil's elderly population. The study identified over 2 million novel genetic variants, providing insights into the health and well-being of older adults.
Dudley Lamming, a renowned expert in aging research, will present his latest findings on how specific dietary amino acids regulate health and longevity. His research aims to understand the molecular mechanisms underlying aging and potential interventions.
A study finds that extreme heat is associated with a significant increase in cardiovascular mortality, particularly among men and non-Hispanic Black adults. The researchers analyzed data from over 3,100 counties in the US and found that each additional day of extreme heat was linked to an average of 600-700 additional deaths per year.
Researchers from IRB Barcelona have discovered that damaged mitochondria accumulation triggers inflammatory processes leading to muscle atrophy. Correcting mitochondrial function through increased BNIP3 levels can mitigate inflammation and muscle loss, offering potential tools for promoting healthy ageing.
A new study found that excessive daytime napping among seniors is associated with an increased risk of developing dementia and Alzheimer's disease. After a diagnosis of mild cognitive impairment or Alzheimer's, daytime napping duration triples, suggesting that the brain's wake-promoting neurons may be affected by dementia pathology.
Global thought-leaders will share their insights into aging and its effects, with a focus on reducing age-associated morbidities and frailty. The conference aims to develop interventions that can slow down or reverse the aging process, benefiting everyone's health and lifespan.
A new study led by UC San Francisco reveals that 87% of seniors with dementia would stop at least one medication if their doctor said it was possible. Polypharmacy contributes to challenges with adherence and adverse interactions, but most patients are willing to reduce their medications.
Researchers at the Salk Institute successfully reversed aging signs in middle-aged and elderly mice using a cellular rejuvenation approach. The treatment, which involves reprogramming cells with four specific molecules, restored youthful epigenetic patterns and improved tissue function without increasing cancer risk.
A new study by Dartmouth's Geisel School of Medicine found higher mortality rates among older adults with cognitive impairment during the COVID-19 pandemic. The study showed a 24% increase in mortality for individuals with Alzheimer's disease and a 36% increase for nursing home residents with ADRD.
A large-scale study aims to understand how individual brains change over time, identifying factors that increase cognitive decline risk and those that confer resilience. The Adult Aging Brain Connectome study will follow 1,000 participants across a decade, collecting brain scans, blood samples, and demographic data.
New Penn State research found that the maximum wet-bulb temperature for humans is lower than previously thought, at around 31°C in warm-humid environments. This finding has significant implications for planning and preparing for extreme heat events.
Researchers found that daily life movement, including housework and self-care activities, significantly benefits cardiovascular health. Women with at least four hours of daily life movement had a 43% lower risk of cardiovascular disease, 62% lower risk of cardiovascular disease death.
A study by Washington State University found that social support can mitigate the risk of heart disease and death in older American Indians. Higher rates of depression symptoms, poor quality of life, and social isolation were linked to increased mortality, but instrumental social support reversed this effect.
A Finnish twin study found that individuals with lower education are more susceptible to the negative effects of cardiovascular risk factors on late-life cognition. The study suggests that higher education can act as a cognitive reserve, helping to mitigate dementia risk.
A new study reveals that social isolation and loneliness can increase cardiovascular disease risk by 8% and 5% respectively. Women who experience high levels of both social isolation and loneliness have a 13-27% increased risk of heart disease, compared to those with low levels.
A study found that racialized immigrants were less likely to report good health, with experiences of discrimination contributing to these disparities. Social isolation and lower socioeconomic status also increased the risk of poorer health.
Ovarian cancer death rates are predicted to decrease by 17% in the UK and 7% in EU countries in 2022. The main contributor is the long-term use of oral contraceptives, reducing the risk by 40%. Other factors include improved diagnosis, treatment, and advancements in treatments for other cancers.
A new study of Chinese older adults found that higher levels of social isolation are associated with having fewer teeth and losing teeth more quickly over time. Despite this, loneliness was not linked to the number of remaining teeth or tooth loss rate.
A study published in Diabetes Care found that walking regularly at greater intensity and taking more steps can lower the risk of developing Type 2 diabetes among adults aged 65 and older. For every 1,000 additional steps per day, the risk is reduced by 6%, with a 12% reduction possible if an average adult takes 2,000 more steps daily.
A new study found a 1,886% increase in opioid-related overdose deaths among U.S. adults aged 55 and older between 1999 and 2019. Contributing factors include ageism, social isolation, depression, and declining cognitive function.
Researchers at Penn State will investigate ways to stimulate muscle growth by increasing ribosome production. Their goal is to find molecular targets that can be used to promote muscle growth without exercise or drugs. This study aims to prevent muscle loss due to aging, cancer, and other chronic diseases.
A recent study published in Alzheimer's & Dementia found that regular exercise enhances the connections between neurons in older adults, maintaining healthy cognition. The research, led by Kaitlin Casaletto and William Honer, suggests that physical activity may help boost synaptic functioning and safeguard against dementia.
A new study by University of Waterloo researchers reveals that for-profit long-term care homes owned by private equity firms and large chains have the highest mortality rates during COVID-19. The study found a correlation between financialization of senior housing and lower quality care, with prioritizing profits over patient outcomes.
A new study has made an Alzheimer's disease biomarker test available to all Canadians, enabling doctors to accurately diagnose the disease even when mild symptoms are present. The test aims to improve care and support for individuals living with Alzheimer's disease and their families.
A new study reveals that extracellular vesicles deliver genetic instructions for the longevity protein Klotho to muscle cells, which declines with age. This finding suggests that EVs could be developed into novel therapies for healing damaged muscle tissue and improving functional recovery in older individuals.
A new study found that cognitive behavioral therapy (CBT-I) prevented major depression in older adults with insomnia, decreasing the likelihood of depression by over 50%. CBT-I was more effective than sleep education therapy in preventing depression and promoting sustained remission of insomnia.
A new index ranks US states based on their support for successful aging across five domains: productivity, security, equity, cohesion, and well-being. The study found that no single domain drives the results, and state policies play a significant role in adapting to an aging population.
A study of nearly 500,000 Medicare patients with long-term dialysis revealed COVID-19 risk factors and associated mortality rates. The research highlights the need for targeted interventions to protect vulnerable populations.
A new UCSF study shows that solo seniors with social support are less likely to need nursing home care. Older adults who said they could count on a friend or relative for assistance in the event of a health crisis reduced their risk of institutional care from 14.2% to 10.9%. The study found that many older adults can take care of thems...
Researchers found that levels of chitinase 3-like-1 increase with age and co-morbid diseases, augmenting SARS-CoV-2 infection. A therapeutic antibody blocks the induction of the ACE2 receptor, potentially paving the way for COVID-19 prevention and treatment.
A study found that younger B-cell non-Hodgkin lymphoma survivors are at a higher risk of developing age-related diseases, including renal failure, pneumonia, and nutritional deficiencies. The research suggests that aggressive treatment regimens may be the underlying factor contributing to this increased risk.
Researchers found that Alzheimer's disease develops by replicating aggregates in individual brain regions, rather than spreading them. The study used human data and PET scans to track the aggregation of tau protein, a key player in the disease.
A new study published in the International Journal of Nursing Studies found that home care patients who prefer a language other than English are more likely to be readmitted to hospital within 30 days. The study suggests that addressing language gaps is crucial for improving patient outcomes and reducing healthcare costs.
The project aims to address rising healthcare costs, health disparities, and expands digital health through advances in AI. It also trains students from different disciplines to develop and apply data science techniques.
Researchers create maps of senescence in heart and lung cells, comparing different types of senescent cells across the lifespan. The goal is to understand how senescent cells contribute to age-related diseases and develop therapies called senolytics.