About The Study: In this study of two community-based cohort studies in midlife (n = 497) and late life (n = 970), racial and ethnic disparities in small vessel cerebrovascular disease were apparent in midlife. In Latinx and white adults, brain aging was more pronounced in late life than midlife, whereas Black adults showed an accelerated pattern of brain aging beginning in midlife. Race and ethnicity disparities in aging and Alzheimer disease and related dementias may be due partially to social forces that accelerate brain aging, especially in Black middle-age adults.
Authors: Adam M. Brickman, Ph.D., of Columbia University in New York, is the corresponding authors.
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(doi:10.1001/jamaneurol.2022.3919)
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JAMA Neurology