Defering bilateral salpingo-oophorectomy beyond age 50 increases risk of ovarian cancer in BRCA carriers. The residual risk of ovarian cancer for older women in good health is considered high enough to warrant preventive surgery.
A cross-sectional study found that structural brain volumes are associated with delay discounting, a key component of impulsive decision-making, in college-aged adults. The multilayer perceptron model provided an accurate estimate of delay discounting, shedding light on the neural basis of impulsive behavior.
Researchers investigating Group B Streptococcus colonization in the birth canal may lead to improved preventative measures for neonatal meningitis. The study aims to understand how GBS attaches to and stays in the vaginal tract, potentially reducing cases of meningitis in newborns.
The study projects that the total number of people with dementia will increase from 124,000 in 2018 to 216,000 by 2040, with those living at home potentially doubling to 170,000. The growth will be driven by an aging population and increased life expectancy.
A study published in PLOS Medicine found that women with type 2 diabetes are more likely to develop mental health conditions, while men experience more cardiovascular and renal complications. The researchers analyzed data from 28,720 men and women in the UK, revealing significant sex differences in disease trajectories.
A cohort study of 544 young survivors of aneurysmal subarachnoid hemorrhage found that 30.2% developed new brain aneurysms over 40 years. Female sex, smoking, and family history of aneurysms were identified as risk factors, with smoking cessation associated with lower risk.
A study found that supercentenarians, people who live to 110 and beyond, have a higher proportion of cancer-killing immune cells called CD4 CTLs. This expansion may help the immune system adapt to age-related challenges, contributing to exceptional longevity.
This study of 186,823 US adults reveals an increasing prevalence of moderate-to-severe cannabis use disorder among males and females between 2021 and 2024, while moderate-to-severe alcohol use disorder prevalence remained stable. The findings highlight significant age and sex disparities in cannabis and alcohol use disorders.
A new study suggests that a video game designed to raise teens' awareness of mental health issues can reduce symptoms of depression on par with in-school programs. The game, PlaySmart, was played by 269 students for up to six weeks, with significant reductions in symptoms reported after only six weeks.
A cohort study found that excessive parental smartphone use is associated with slower language development in children, while digital device ownership is linked to lower concurrent language performance. The study highlights the importance of considering screen use in the broader family context when evaluating children's language develo...
A cohort study of 13,585 insured patients found racial disparities in endometrial cancer survival, with greater imbalances in risk of adverse tumor types and distant disease. Younger black patients had a 43% larger disparity compared to their white counterparts.
After COVID-19 pandemic restrictions relaxed, Kawasaki disease incidence rebounded in Japan, with distinct age-dependent patterns. Nonpharmaceutical interventions may have contributed to the observed greater rebound in older children, while infants showed minimal changes, suggesting different exposure pathways.
This study examines associations between early life BMI and childbirth timing, as well as fertility outcomes among Danish women. Childhood body size is found to be associated with the timing of childbirth, highlighting the importance of addressing reproductive health early in life.
A study of 3786 children found no significant associations between screen use and developmental difficulties, except for very high use of electronic games. Early high screen use was associated with greater difficulties at 10 years old, but not sustained at 15 years.
A new study published in BMJ Public Health found that people who live by the coast in midlife are more likely to have two or more diagnosed chronic conditions. The researchers attribute this to higher deprivation and selective migration patterns, where individuals with worse health tend to remain in or move to coastal areas.
This study analyzed 9845 Ukrainian refugee children aged 5 and under in Southern Poland, identifying 5 distinct health care utilization profiles. The findings suggest that refugee-hosting countries must prioritize emergency and inpatient care following a crisis to rapidly adapt health care resources.
High LDL-C led to 3.6 million deaths and 90.7 million disability-adjusted life years in 2023, despite declining mortality rates. The absolute burden increased due to population growth and aging, with regional disparities emerging.
A new international study reveals that age plays a significant role in shaping global food-related greenhouse gas emissions. The research found that adolescents and young adults consistently have the highest per-capita dietary greenhouse gas emissions globally, while population aging has become an increasingly important driver of total...
This study found that young, non-Hispanic white women who are physically active and drink heavily are more likely to engage in intentional outdoor tanning. Intentional tanning is associated with increased risk of sunburn and skin cancer, highlighting the need for targeted strategies to reduce this behavior.
A new study from the University of Georgia suggests that higher levels of change in testosterone during early puberty are linked to increased emotional difficulties in girls between ages 10 and 12. The study found that physical development alone is not enough to predict depression and anxiety symptoms in adolescent girls.
A study found that measles-containing vaccines were administered to only 15% of children in this age group between 2015 and 2025. This proportion remained stable over time, but disparities in vaccine uptake existed among minoritized racial and ethnic groups.
A pooled data analysis of 44 countries reveals that early menopause is more prevalent in rural areas, but education and delayed childbearing minimize the risk. The overall prevalence was 7% among women aged 30-49, with the highest rates found in Ethiopia, Indonesia, and Myanmar.
Researchers at UCF's College of Medicine have identified molecular changes in the liver that occur when space travelers experience radiation and microgravity, leading to accelerated aging. The study suggests that these changes could be treated with antagomirs, providing a promising future for therapies to combat age-related diseases.
Research from the University of Georgia found that adverse childhood experiences can negatively impact romantic relationships, leading to lower relationship satisfaction. Couples who struggle with everyday interactions and communication may be more likely to experience depression, anxiety, and loneliness in adulthood.
A cross-sectional study of Medicare beneficiaries age 65 and older found friend caregivers to be an integral part of the caregiving network. They provide essential care without expecting compensation or reimbursement.
A UMD-led study reveals that wild bats balance different types of immune defenses based on sex, age, and competition for mates. The researchers found that male bats rely more on rapid-response immune defenses, while females invest in targeted responses to pathogens.
A mouse study found that social isolation during adolescence impairs emotion recognition and social behavior in adulthood. Resocializing does not reverse these behavioral changes. The study also showed that socially isolated adult mice were unable to tell the difference between stressed and unstressed mice.
A study from the University of Gothenburg found that patients with chronic pain do not have equal access to specialized rehabilitation programs. Sociodemographic factors such as education, age, sex, and region of birth play a significant role in determining participation rates. The study suggests that addressing these disparities is cr...
The study found that an abortion ban in Texas was associated with a worsening of maternal mental health among reproductive-age mothers. This highlights the need for strengthened support for post-Dobbs policy environments.
A cross-sectional study found that colorectal cancer screening participation increased after an organized population screening program, but socioeconomic disparities remained. Younger age groups, single households, and lower-income individuals still lag behind in screening uptake.
A new study found that one in three middle-aged American adults can't consistently read prescription instructions correctly or recall details from doctor visits involving chronic conditions. The researchers recommend simplifying health information using plain language to improve patient outcomes and reduce harm.
A new study found that social connections can help compensate for the loss of mentally stimulating interactions linked to work, with different types of relationships benefiting women and men. The researchers used data from 27 European countries and found that strong social networks appear to buffer the cognitive disadvantage of not wor...
A cohort study found that smartphone acquisition at age 13 was linked to increased risk of insufficient sleep at age 14. Excessive smartphone use was also tied to higher odds of depression and obesity. Limiting screen time may protect adolescents from these outcomes.
A cross-sectional study found early age–onset colorectal cancer patients with improved overall survival but delayed treatment experienced worse outcomes. Language barriers may be a modifiable risk factor contributing to these delays.
Chlamydia notifications decreased in seven European countries, with significant declines among young people. The decline was mainly seen in Sweden, Denmark, England, Finland, Ireland, Norway and the Netherlands, with case numbers dropping by up to 32% in some countries.
A nationally representative study found a nearly 4-fold increase in type 2 diabetes prevalence among US children and adolescents between 10 to 17 years old. The substantial rise is concerning due to the disease's lifetime risk of severe complications and premature deaths.
Decades of research on UK birth cohorts suggest a 'generational health drift' where more recent generations experience poor health earlier in life, particularly obesity and mental ill health. This trend is driven by worsening social and environmental exposures rather than improvements in healthcare.
A nationwide implementation of a uniform multimodal prehabilitation program significantly reduced complication rates and length of hospital stay among patients undergoing colorectal cancer surgery. This study highlights the benefits of standardized preoperative care in improving patient outcomes.
A post hoc analysis of a randomized clinical trial found high-dose vitamin D3 supplementation in pregnancy to be positively associated with visual memory, verbal memory, and flexibility among offspring at age 10. This strengthens evidence on the association between prenatal vitamin D exposure and childhood cognition.
The study found substantial state-level variation in HPV vaccine uptake, with Northeastern states exhibiting higher rates and Southern states showing lower rates. Several sociodemographic factors were not significant predictors of vaccination rates, highlighting the need for targeted interventions to improve vaccine uptake.
The US had substantially higher death rates between 1999 and 2022 compared to other wealthy nations, with cardiovascular diseases being the leading cause of excess mortality. An estimated 12.7 million US deaths could have been averted during this period if US mortality rates mirrored those of its peers.
Unsecure firearm storage is common among older adults with subjective cognitive decline, despite clinical guidance recommending secure storage for those with cognitive symptoms. The study highlights the need for improved household practices and access to fire safety education.
Cancer cases are on the rise among younger adults in England, with a significant increase in bowel and ovarian cancer rates. The study found that excess weight is a key contributor, but it's unlikely to fully explain this trend, as trends in risk factors such as smoking and diet have been stable or improving over the past decade.
Research explores how differences in brain development, age, and sleep affect EEG signals recorded from awake individuals. The study reveals that brain signals during wakefulness depend on prior sleep, with effects differing between children and adults.
The study found that out-of-state Chicago Abortion Fund callers traveled more than 3 times the distance to Illinois after Dobbs compared to before. These callers were also more likely to have private or no insurance, be from rural areas, and receive hospital-based care during their pregnancy.
A study estimates annual mortality rates among US Immigration and Customs Enforcement (ICE) detainees between 2004 and 2026. The analysis reveals notable shifts in age and cause of death patterns over the two-decade period, providing valuable insights into the health risks faced by this population.
Researchers developed a nasal spray that reversibly reduces brain inflammation, restores cellular power plants, and improves memory. The treatment bypasses the brain's protective shield through intranasal delivery, suppressing chronic inflammation and promoting successful brain aging.
Adults aged 75 or older without adenoma on prior colonoscopy have lower risk of subsequent colorectal cancer and CRC death. Despite this, those with prior adenoma may consider deprioritizing surveillance colonoscopy relative to other health concerns.
A national study found that unmet health-related social needs are associated with lower colorectal cancer screening rates, particularly among adults aged 50-64. Addressing these needs may support age-specific strategies to improve screening rates.
A cohort study found that individuals diagnosed with ADHD at a younger age tended to perform better academically, receiving more education and experiencing lower dropout rates compared to those diagnosed closer to age 16. This suggests that targeted support for early diagnoses could help prevent school dropout.
Researchers at NYU School of Global Public Health found that people living in neighborhoods with fewer social and economic opportunities have higher levels of CDKN2A RNA, a measure of cellular aging. This suggests that structural conditions may be biologically embedded and influence aging processes over time.
The Alliance for Clinical Trials in Oncology is enrolling adolescent and young adult cancer patients in various trials, including genetic services and treatment studies. These trials aim to address longstanding gaps in care and improve outcomes for AYAs with cancer.
A higher testosterone level does not always indicate well-being in men, according to a study at the University of Gothenburg. Muscle health and inflammation are linked to testosterone levels, but symptoms like fatigue and depression have weaker connections.
The study found that women with pregnancy-associated spontaneous coronary artery dissection (P-SCAD) have a higher risk of cardiovascular events, including dissections and aneurysms. Women with P-SCAD also experienced less recovery in left ventricular ejection fraction compared to those without P-SCAD.
Adolescents who spend more time on social media tend to struggle with recognizing and pronouncing words. However, frequent social media use is also linked to faster information processing and shorter reaction times.
A new study found that walking pace is a strong predictor of mortality risk, especially in people with existing health conditions. Combining walking pace with other physical measures improved mortality predictions, suggesting a simple and cost-effective way to identify high-risk individuals.
Children with metabolically healthy obesity at treatment initiation have an increased risk of type 2 diabetes, hypertension, and dyslipidemia. Reduction in BMI z score is associated with reduced cardiometabolic risk, suggesting treatment should be recommended for these children as well.
Researchers at the University of Gothenburg have identified a protein, ATF4, linked to increased metastasis and recurrence in lung cancer. The study reveals that older individuals' tumors are smaller and grow more slowly, yet more likely to have spread when detected.
A population-level cohort study of 20 low-mortality countries found that females aged 35-60 have higher cancer mortality rates than males, despite similar treatment and diagnostic pathways. The study highlights the need for targeted action to improve the prevention, early detection, and treatment of female reproductive cancers.
A study found that college students with lower self-control and habitual use of short-form videos experience poorer sleep health and higher stress, but not diminished academic performance. Researchers suggest that institutions of higher learning and society can help by providing holistic mental health and student health outreach services.