About the Study: The residual risk of ovarian cancer for older women in good health is sufficiently high to consider preventive surgery. BRCA1 carriers who defer BSO until age 50 years may face a substantial risk of developing ovarian cancer.
Corresponding Author: Vasily Giannakeas, PhD, Prosserman Centre for Population Health Research, Lunenfeld-Tanenbaum Research Institute, Sinai Health System, 60 Murray St, 5th Floor, Toronto, ON M5T 3L9, Canada ( giannakeas@lunenfeld.ca ).
10.1001/jamasurg.2026.4356
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JAMA Surgery