A new study offers hope that kidney transplant patients may one day have a more effective treatment regimen. The Phase 2 pilot study showed improved kidney functioning in all patients who completed the study, with no patients experiencing rejection due to antibodies produced by the immune system.
A retrospective analysis of 94 adult patients who underwent PEEK cranioplasty found that surface architecture may influence postoperative healing, with smooth implants associated with higher rates of wound complications and infections. Perforated implants showed lower rates of major fluid collections, especially in trauma patients.
A study published in JAMA found that salpingectomy significantly lowers the risk of developing tubo-ovarian carcinoma. The procedure, typically performed during unrelated pelvic or abdominal surgery, is now recommended as a preventive measure for eligible women.
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Researchers found that patients seen by cardiologists had lower mortality rates and fewer serious heart problems, including heart attack, sudden failure, or irregular heartbeat. The study suggests close teamwork between surgical and heart teams can improve outcomes after major surgery.
A new AI-powered model predicts patient survival and risk stratification for spinal metastasis, allowing for more informed treatment decisions. The model achieved high predictive accuracy using large-scale clinical data from Japanese patients.
Researchers at the University of Houston have discovered that loss-of-function in epicardial proteins leads to left ventricular noncompaction, or spongy heart, causing pediatric-onset heart failure. A new therapeutic approach may prevent babies from being born with this life-threatening disease.
A recent University of Michigan study analyzed over 60 million Medicare participants and found that total visits remained stable or declined slightly through June 2024. Despite widespread adoption of telehealth, overall healthcare visits stayed steady or decreased, contradicting predictions of increased utilization.
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The Vanderbilt Transplant Center achieved a record 960 solid organ transplants in 2025, saving 85 more patients than in 2024. The center's heart transplant team set a new world record for the second year in a row with 210 adult and pediatric heart transplants.
A clinical trial from Finland found that wearing a cast for six weeks is comparable to surgery for healing unstable ankle fractures, with fewer treatment-related harms. The study's results support the use of conservative treatment approaches to stabilize the ankle mortise and promote fracture union.
The study found that medical tourism postoperative complications may cost the NHS up to £20,000 per patient. The analysis of existing data revealed that patients who underwent surgery abroad were more likely to experience moderate to severe complications, with treatment costs ranging from £1058 to £19,549.
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The new program combines limb preservation, amputation care, and reconstructive solutions like osseointegration to improve identity, functional outcome, and quality of life for patients. Patients will receive coordinated, personalized, and expert care that supports their recovery and promotes sustained overall health.
A study found that the rate of opioid use disorder medication use among surgical patients increased significantly between 2016 and 2022. The majority of users were taking buprenorphine, which has advantages in safety and pain control compared to other options.
A new study reveals that people with an unexpectedly high metabolic BMI have up to a five times higher risk level for diseases such as diabetes and fatty liver. Metabolic BMI is based on advanced metabolomic analyses and identifies obesity-linked changes in metabolism that can be present even at normal weight.
Both bariatric surgery and semaglutide treatment were associated with significant fat mass loss, moderate fat-free mass loss, and an improved FFM to fat mass ratio. These findings support interventions aimed at preserving muscle mass while promoting weight loss.
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Two new studies found that around 1 in 8 day-case surgery patients are admitted to hospital for complications, while 1 in 14 develop chronic pain at the operative site. Chronic post-surgical pain is more common in certain procedures and among patients with medical problems, with orthopaedic and breast surgeries showing higher rates.
Researchers at NIH and Emory School of Medicine have successfully performed a minimally invasive coronary artery bypass without cutting the chest wall. The new technique, called ventriculo-coronary transcatheter outward navigation and re-entry (VECTOR), creates a new route for blood flow that is safe from potential blockages.
A study found that high PD-L1 levels are associated with increased risk of lymph node metastasis and poorer recurrence-free survival rates in patients with pulmonary adenocarcinoma. This suggests that PD-L1 expression may serve as a potential indicator for early postoperative recurrence.
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A new study published in JAMA Network Open found that older adults living in economically disadvantaged neighborhoods spend significantly fewer days at home after a hip fracture. The researchers analyzed Medicare data and found that people in the most deprived areas spent about 23 fewer days at home compared to those in less disadvanta...
A simulation study forecasted potential injury reductions in the US with AV adoption, suggesting a possible decrease in road traffic injuries. However, predicted confidence intervals remain broad, and no scenario reduced injuries outside of these bounds.
A systematic review found that pancreatic cancer surgery significantly increases the risk of new-onset diabetes mellitus (NODM), particularly in patients with known risk factors. The study analyzed 45 studies and found an overall incidence of NODM of 24.5%, with a higher rate in those who underwent distal pancreatectomy.
A study highlights how social media is transforming neurosurgical education, collaboration, and case consultations globally. Platforms like Neurosurgery Cocktail have democratized neurosurgical knowledge, supporting high-level discourse among experts.
A study from Rangsit University shows that a simple bypass protocol guided by mean transit time can improve symptoms in 80% of patients with chronic cerebral occlusion or moyamoya disease. The protocol uses non-stress testing to evaluate cerebrovascular reserve and predict postoperative improvement.
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A targeted treatment approach significantly reduces moderate and severe acute kidney injury after major surgery in high-risk patients identified by biomarkers. The study shows that a closely monitored set of clinical measures provides effective protection in the first hours after surgery.
Using GLP-1 receptor agonists may lower the risk of vertebral compression fractures and related surgical interventions in people with type 2 diabetes. The study suggests that these medications have a bone-protective effect, offering benefits for patients.
A Rutgers Health study found that patients aware of family members' past gallbladder surgery were more likely to seek early help and less likely to undergo high-risk, emergency gallbladder removal. This knowledge helped doctors avoid misinterpreting symptoms such as chest pain and nausea, leading to earlier diagnoses and treatments.
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A study of 8,273 patients found that tranexamic acid significantly reduced the need for blood transfusions and did not increase the risk of blood clots. The medication promotes blood clotting, essential to stop bleeding during surgery, without increasing life-threatening complications.
NEJM Clinician curates highly relevant clinical insights from over 150 peer-reviewed journals to give physicians clear guidance without the noise. The weekly publication delivers summaries and commentary in a concise, 30-minute read, helping healthcare providers stay informed and confident in their decisions.
A study found cryopreserved platelets to be a cost-effective option for managing surgical bleeding in cardiac surgery, dominating liquid-stored platelets in this setting. Further investigation is required to assess the economic benefits of cryopreserved platelets in broader populations.
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A large clinical trial published in JAMA Surgery shows that prehabilitation can reduce disability after surgery in older adults with frailty, provided they fully participate in the program. Participants who completed at least 75% of exercises had significantly lower levels of disability after surgery.
Researchers found that patients who can walk at least 1 meter per second before hip replacement have significantly better mid-term postoperative outcomes. This simple and reliable predictor could help physicians determine when to refer patients for surgery, and preoperative rehabilitation programs could be developed.
A new study reveals thousands of NHS knee replacement operations are cancelled annually for avoidable reasons, costing millions and prolonging waiting times. Lack of available beds and medical ineligibility were the most common causes, with many cancellations avoidable with advance planning.
A nationwide observational study from SWEDEHEART reveals that patients with type 1 diabetes have a significantly higher risk of stent complications compared to those without diabetes. The study emphasizes the need for adapted treatment and follow-up strategies for this patient group.
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Researchers at University of California San Diego School of Medicine found that streamlined surgical preference cards can significantly reduce hospital waste and improve operational efficiency. By analyzing thousands of surgeries, they identified unnecessary items and optimized lists to save up to $3 million over five months.
A new study by Nagoya University researchers found that laparoscopic surgery significantly reduces blood loss and improves jaundice recovery compared to traditional open surgery for treating biliary atresia. The study analyzed data from 356 children who had surgery at two months old, tracking their outcomes for an average of 13 years.
A new clinical trial enrolls patients at the University of Cincinnati to study the effects of extended tranexamic acid dosing on recovery outcomes for young athletes after ACL reconstruction. The trial aims to test whether this approach can reduce pain, swelling and promote earlier movement in patients.
A study published in Journal of Translational Medicine found that successful root canal treatment can reduce inflammation linked to heart disease and improve levels of blood sugar and cholesterol. The researchers discovered a link between monitoring blood metabolic markers after dental treatment, which could help assess recovery and risk.
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A new study by Stanford Medicine researchers finds that a personalized prehab coaching program can motivate patients, enhance their immune system, and result in fewer complications. The study suggests that one-on-one help is crucial for successful prehabilitation, leading to better adherence and improved clinical outcomes.
A population-based cohort study found that the cumulative incidence of scrotal surgery among male living kidney donors was 1 in 8 after 20 years, compared to 1 in 143 for non-donors. Most males who donate a kidney won't develop this complication, but it's essential to inform past and future donors about the risk and potential symptoms.
Researchers found that tubeless anesthesia significantly reduces postoperative complications, promotes enhanced recovery, and lowers costs in selected patients. The study also showed improved respiratory function and reduced intubation times.
This study evaluates the effectiveness of staged versus simultaneous bilateral lung volume reduction surgery in patients with severe emphysema. Both approaches significantly improve pulmonary function tests, but the staged approach offers a better composite outcome of overall survival and transplant-free survival.
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A team of researchers at Osaka Metropolitan University has successfully treated spinal compression fractures in rats using stem cells derived from adipose tissue. The study found that these cells can promote bone healing and regeneration, making them a potential solution for osteoporotic vertebral fractures.
Researchers have identified iron-manganese alloys as promising candidates for temporary bone fixation. These alloys combine strength, biocompatibility, and degradation properties, allowing them to support bone healing while degrading naturally. However, challenges remain, including controlling the release of manganese, which can pose t...
A recent survey conducted by Orlando Health found that over one-third of men (38%) would rather endure stressful situations than discuss their prostate health. The reluctance to address this common issue often leads to delayed diagnosis and treatment, affecting men's quality of life.
A new, fully degradable cranial clamp made from poly-L-lactic acid has been developed to address traditional fixation system drawbacks. The study compared its performance to Aesculap CranioFix through laboratory tests and a clinical trial involving 90 patients, showing improved safety and healing outcomes.
A new project led by University of Delaware engineer Michael Hast aims to develop radiation-free imaging techniques that identify problems with bone healing sooner. The team uses 3D computational models and recent advances in magnetic resonance imaging (MRI) to estimate the strength of a healing bone and simulate real-world stresses.
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Researchers have developed a novel vaccine strategy using biomaterial scaffold vaccines to protect against Staphylococcus aureus infections in orthopedic device implants. The vaccines, made with immune cell-attaching molecules and S. aureus-specific antigens, create a beneficial immune response that significantly lowers bacterial burden.
Researchers have developed a new method to create smaller soft robots using 'bubble magic' that can navigate and operate within the body's narrow orifices. The soft robots, powered by fluid, have mirror-smooth skin and are ten times slimmer than previous versions.
A team of biomechanical engineers and surgeons has developed a 3D-printing soft robot that can accurately deliver hydrogels to the vocal cord surgical site. The device, which is only 2.7 mm in size, can reconstruct tissues removed during surgery and potentially prevent fibrosis and stiffening of the vocal cords.
A study reveals that collared fully HA-coated femoral stems reduce the risk of early postoperative femoral fractures in total hip replacement patients, but also increase intraoperative complications. The findings suggest these stems may be a safer choice for surgeons when deciding on implant selection.
Dr. Bethany Slater, a highly skilled and compassionate surgeon, has been appointed as Division Chief of Pediatric Surgery at Mount Sinai Kravis Children's Hospital. She will focus on advancing surgical excellence, expanding minimally invasive techniques, and enhancing multidisciplinary care for children and families.
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A team of researchers has proposed a novel ultrathin flexible sensor inserted endovascularly to detect Type-I endoleaks with maximum rupture risk. The sensor is robust enough to withstand dynamic processes and exhibits long-term stability and functionality.
A new Northwestern University study reveals that abnormal cells in transplanted lungs engage in harmful 'conversations' with the immune system, leading to damage and rejection. The findings provide a comprehensive roadmap for treating chronic lung allograft dysfunction and other scarring lung diseases.
A new noninvasive method uses multi-echo ultrashort echo time MRI and shear wave elastography ultrasound to assess the structure and function of the Achilles tendon in professional ballet dancers. The study found that dancers tend to have more tendon stiffness, which corresponds with prior observations of a training effect.
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Researchers identified a set of biomarkers that can predict blood pressure outcomes five years after adolescents underwent metabolic bariatric surgery. The study found that blood-based biomarkers were more accurate than traditional risk factors, suggesting a potential new approach to predicting long-term blood pressure outcomes.
A recent study published in JAMA challenges the common practice of individualizing blood pressure targets based on preoperative nighttime mean arterial pressure. The findings suggest that this approach may not be effective for high-risk patients undergoing major abdominal surgery.
Researchers developed a latex-based tissue adhesive to prevent seroma formation and prolonged lymphorrhea after axillary dissection. The study found that the adhesive significantly reduced wound exudate volume and allowed patients to be discharged earlier, with no complications reported.
A recent study published in JAMA found that intraoperative blood pressure management with mean arterial pressure goals did not improve functional disability at 6 months postoperatively. The study suggests standard intraoperative blood pressure management may be sufficient for patients undergoing surgery.
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A cohort study found that early extracranial surgery was associated with adverse outcomes in function, cognition, and disability after moderate-severe traumatic brain injury. The study suggests that further research is needed to determine if surgical timing or other interventions can improve long-term deficits.
A national survey of first-year fellows in minimally invasive gynecologic surgery found significant gaps in the use of FDA-cleared containment systems during laparoscopic hysterectomy and myomectomy. The majority of fellows cited cost as the main reason for using less expensive, off-label retrieval bags instead of FDA-cleared systems.
Current minimum case volume standards for complex surgical procedures no longer align with contemporary best practices. Studies have shown that fewer cases are now needed to meet benchmark 30-day mortality rates over time.