Articles tagged with Aging Populations
Researchers identify key neurons and signaling pathway regulating female activity before ovulation. Discoveries could lead to new treatments for menopause that sidestep estrogen and reactivates the circuit with CRISPRa technology.
A study of nearly 179,000 veterans aged 65+ found that maximizing the dosage of an existing medication can lead to better adherence and lower blood pressure. Adding a new medication shows a slim advantage in some cases, but with risks associated with polypharmacy.
A new study led by UCSF indicates that depression in early adulthood can increase the risk of cognitive impairment and dementia. The research found that moderate or high depressive symptoms were associated with a 73% higher odds of cognitive impairment among older participants.
A new study published in PNAS suggests that China's declining birth rate and aging population may not negatively impact future prosperity. The researchers found that higher education levels among women can lead to increased labor force participation, potentially offsetting the negative effects of population aging.
Skeletal muscle secretes a molecule that regulates around 35% of liver functions, with the remaining basal functions independent of muscle activity. Ageing alters this communication, leading to non-optimal functions and accelerated ageing.
A study of over 2,000 European retirees found that internet usage after retirement is associated with better cognitive scores. Specifically, female retirees who regularly surfed the internet recalled more words on a word recall test compared to their non-internet-using counterparts.
Researchers found that aging workforces, characterized by a higher ratio of workers 56 and older to those ages 21-55, are associated with increased robot deployment in 60 countries. This study suggests that automation adoption is partly driven by labor shortages, particularly middle-aged labor needed for blue-collar work.
Researchers analyzed large datasets to find biomarkers that could help select immunotherapy treatment for older patients. The analysis suggests that factors such as mutational burden and immune checkpoint protein expression are associated with increased response to immunotherapies in older patients, despite lower general immunity.
Researchers found that seniors moving from low-mortality areas to high-mortality areas experience a significant decrease in life expectancy. On the other hand, urban areas on the East and West Coasts have positive effects on longevity for seniors, while Midwestern metro areas score well. The study also identified parts of the deep Sout...
Dr. Maria Carolina Florian will present her latest research on aging hematopoietic stem cells, challenging the concept that aging is an irreversible process. Her work aims to improve tissue homeostasis and regeneration by targeting epigenetic polarity and functionally rejuvenating aged HSCs.
A recent study by MPIDR researchers found that participating in the labor market until age 67 slows cognitive decline and protects against cognitive impairment. This effect holds regardless of gender or educational/occupational attainment, with a slowed rate of cognitive decline rather than improved function.
Researchers created Community ASAP to help locate missing people with dementia, engaging community citizens as volunteers. The app aims to address the lack of alerts for this population, which has a high risk of wandering and experiencing serious injury or death within 24 hours.
Researchers at the University of Pittsburgh School of Medicine have found that brain tissue inflammation is a key driver of Alzheimer's disease progression. By targeting neuroinflammation, they believe combination therapy could be more effective in reducing amyloid plaque formation and limiting tau fiber spread.
Dr. Brian Kennedy will discuss his latest research on the path to longer lifespan and healthspan, highlighting potential smooth or bumpy routes to achieving healthy longevity. The conference aims to bring together experts to share groundbreaking research and developments in aging and drug discovery.
Dr. Anne-Ulrike Trendelenburg will present research on targeting common pathways to treat age-related diseases, including sarcopenia and premature aging diseases. The conference brings together experts from academia and industry to discuss progress in the molecular, cellular and organismal basis of aging.
Researchers analyze impact of risk factors on heat-related mortality at different spatial scales, finding age, education, and socioeconomic status are key contributors. A localized approach is needed to address specific conditions at the city, region, and neighborhood levels.
Kai-Fu Lee will present his latest research on AI and its applications in healthcare at the 8th Aging Research & Drug Discovery Meeting. The conference aims to discuss the molecular, cellular, and organismal basis of aging and search for interventions.
Researchers found that states have implemented new autism-specific Medicaid programs, with the most common type being the 1915(c) waiver authority, providing home and community-based services. The study suggests that further replication of successful efforts is needed to improve access to services for individuals on the autism spectrum.
Dr. Sibylle Jäger will present a new research on a salicylic acid derivative that prevents oxidative damage in skin, exploring its potential as an intervention for aging. The conference aims to discuss the latest progress in understanding the molecular basis of aging and finding interventions.
VitaDAO, a decentralized intellectual property collective, is funding early-stage longevity drug development. The conference will discuss novel approaches to funding aging research, with experts sharing their latest groundbreaking research.
Dr. Nir Barzilai will present his latest research on neurotherapeutics from genetic-based discovery in centenarians, focusing on designing and delivering treatment for every disease. The conference aims to bridge clinical, academic, and commercial research to find practical solutions for extending healthy lifespan.
Dr. Anne Brunet will present her latest research on mechanisms of brain aging and rejuvenation, focusing on novel genes regulating longevity and neural stem cell aging. The conference aims to bridge clinical, academic, and commercial research to develop practical solutions for extending the healthy lifespan of everyone.
A Dartmouth research team led by Glyn Elwyn is testing interactive educational approaches to boost vaccine confidence among unvaccinated long-term care workers. The study aims to measure vaccine confidence, knowledge, and trust in the COVID-19 vaccines.
A new study reveals that people's feelings about their age are closely tied to their physical health and well-being. Subjective age discordance, the difference between how old one feels and wants to be, was found to be more pronounced in older adults but fluctuated more in younger adults.
The Gerontological Society of America's Journalists in Aging Fellows Program aims to educate journalists about issues in aging and disseminate information on new scientific findings. The fellowship program has supported over 700 news stories, equipping reporters with accurate fact-based coverage for diverse audiences.
Researchers found a significant association between estrogen receptor α PvuII polymorphisms and dementia in a Brazilian cohort. The study suggests that this polymorphism may contribute to the development of dementia, particularly in elderly populations.
A study found that administering ghrelin to older mice helped restore muscle mass and strength, suggesting a potential new treatment strategy. Unacylated ghrelin (UnAG) was shown to preserve muscle function and reduce the risk of age-related sarcopenia without causing weight gain.
Researchers propose using an equivalency criterion to determine the old age threshold based on a fixed remaining life expectancy, which is consistent with the equivalency criterion. This approach highlights the need to reevaluate traditional measures of aging and provides a more nuanced understanding of population aging.
The world's population aged 60 years and older is expected to reach 2 billion by 2050, with significant disparities in health conditions across the globe. The IIASA study reveals constant prevalence rates of severe activity limitations in low- and middle-income countries for the next 30 years.
A study published in Frontiers in Psychology found that Dance Movement Therapy (DMT) improved mood and physical activity in grandmothers, while also allowing their female dance/movement therapists to process their grandparents' eventual death. The therapy promoted a strong intergenerational bond between the two groups.
Researchers explore public health interventions to foster healthy aging, including community development and population surveillance. The study highlights the critical role of systems in addressing aging-related challenges.
The study models labor force participation, education, and integration of immigrant populations to alleviate population aging's negative economic consequences. Higher immigration volumes with low education and integration can increase economic dependency.
A study by Hiroshima University found that financial literacy is key to understanding existing legal and social services for people with dementia. Financially literate individuals are more aware of systems like adult guardianship and civil trust, which can help prevent misuses of power and ensure continued economic participation.
A UMass Lowell researcher is developing advances in safety for home care aides and clients as the field faces an aging population, technology changes, and safety challenges. The goal of the project is to produce guidelines, develop safety tools, and evaluate their effectiveness.
A new healthcare framework aims to improve diagnosis and treatment of age-related diseases by classifying and staging severity. The framework, developed by an international team of experts, includes a comprehensive classification system for aging-related diseases in all organs.
Research found that living alone is positively associated with common mental disorders across all ages and sexes. The prevalence of people living alone was linked to an increased risk of mental health issues, with loneliness explaining 84% of the association.
Researchers explore deprescribing as a solution to polypharmacy, highlighting factors contributing to its prevalence in older adults. The study identifies complex healthcare delivery issues, co-morbidities, and marginalization of patients as key contributors.
A Montreal bike path network expansion has left children without equal access despite increased growth between 1991 and 2016. Researchers warn that targeting cycling infrastructure for children is crucial for understanding the benefits of bicycling once they become adults.
A team of researchers at UCSB has developed a retinal implant to replace support cells damaged by dry AMD. The phase 1/2A trial showed improvement in one patient's vision while maintaining the condition of others.
A recent study published in British Journal of Clinical Pharmacology found a significant link between nonsteroidal anti-inflammatory drugs (NSAIDs) and an increased risk of atrial fibrillation. The research highlights the importance of closely monitoring NSAID use for heart health, particularly among high-risk individuals.
A new study found moderate-to-vigorous physical activity levels are similarly low in older adults with symptomatic knee osteoarthritis and those from the general population without osteoarthritis or knee pain. The findings highlight the need for efforts to increase physical activity for all.
Small Ontario municipalities are less prepared to support aging adults due to lack of planning and funding, according to a University of Waterloo report. The report recommends that municipalities adopt age-friendly policies and strategies, as seen in British Columbia, to better support their aging populations.
A University of Michigan study found that older Americans report feeling dramatically healthier than 14 years ago. However, the majority of health gains went to high-income, well-educated, and white individuals. Researchers used data from 55,000 adults to analyze health trends by education, race, and income.
According to an 18-year analysis, 56% of individuals aged 57-61 are likely to spend time in a nursing home, with high out-of-pocket costs for some. Lifetime spending averages $7,300, but some face expenses over $47,000.
A growing population of older adults with HIV is being overlooked due to implicit ageism, which contributes to poor mental and physical health outcomes. The combination of stigma, social isolation, and negative expectations about aging can lead to depression, loneliness, and chronic disease.
A multidisciplinary research team is focusing on the economics of providing transportation for rural elderly populations. The study aims to identify innovative solutions and information technology that can improve the coordination and efficiency of rural transit systems.
A new study predicts population aging will peak before the end of the century in China and Germany, with the US experiencing little aging. Traditional projections underestimate the impact of increasing life expectancy on age structures.
Researchers evaluated macular changes using spectral domain type optic coherence tomography in 63 eyes of patients with acute NAION, finding normal posterior pole in 33.3% and subretinal fluid in 34.9%. The study suggests that macular OCT can identify coexistent macular abnormalities and monitor disease progression.
A new paper reviews nutritional considerations for healthy aging and reduction in age-related chronic disease. The authors emphasize the need for dietary resilience, protein requirements, and biomarkers to understand the impact of advancing age on muscle mass and nutrient absorption.
A study found that performing even a third of the recommended activity is beneficial for older adults with arthritis. Participants who achieved a minimum of 45 minutes of moderate activity, such as brisk walking, per week were 80% more likely to improve or sustain high function over two years.
The new data sheet explores population trends in Europe, highlighting the impact of aging, migration, and pension systems. Eastern European countries show the fastest rate of population aging, while standard indicators suggest a slower rate.
A new study published in JAMA Oncology found that frailty prevalence among young bone marrow transplant survivors is similar to that of the elderly population. Frailty was associated with a more than twice increased risk of subsequent death in these patients.
Researchers warn of a looming crisis in cardiothoracic surgical services as the number of trained professionals dwindles and demand increases, particularly among an aging population. By 2030, there will be approximately 3,000 cardiothoracic surgeons needed to cover 854,000 cases, with each surgeon's workload projected to increase by 121%.
A new study found no change in epilepsy incidence among younger patients over the past 40 years, while an increase was observed among older patients. This suggests that progress in preventing new cases of epilepsy has not been made, particularly among the elderly population.
A new study reveals that fitness level impacts brain connectivity in older adults, with more fit individuals showing stronger brain connections. The research suggests that cardiorespiratory fitness has a positive effect on brain health as people age.
An 11-year study of over 425,000 patients found that atrial fibrillation's contribution to ischemic stroke risk was negligible in those with multiple comorbidities. The study suggests that stroke prevention should focus on the combined effects of multiple risk factors rather than a single factor.
A study analyzing data from over 8,000 married couples found that the physical health and cognitive functioning of a person's spouse can greatly affect their own quality of life. The research suggests that targeting both partners' health and cognition is crucial for improving overall well-being in older adults.
A new study finds that nearly one-quarter of Americans over 65 are currently or at risk of being 'elder orphans', a vulnerable group requiring greater awareness and advocacy efforts. This population faces risks such as functional decline, mental health issues, and premature death due to lack of social support.
Research finds that faster increases in life expectancy do not necessarily lead to faster population aging when using alternative measures of age. Instead, the study shows that faster increases in life expectancy can lead to slower population aging when taking into account the time left to live.
A recent study found that nearly 290,000 older adults from the US volunteered abroad in 2012, a 60% increase from the previous decade. Host organizations are clamoring for baby boomer volunteers with professional skills to offer. The average age of these volunteers was over 64, and they spent an average of 13 weeks abroad.