A new Israeli study explores physician attitudes toward emerging anti-amyloid treatments for Alzheimer's disease. Key findings highlight the need for multidisciplinary collaboration to address financial and logistical barriers, emphasizing education, cost-benefit analysis, and improved insurance coverage.
A new supplement celebrating the 100th volume of the Journal of Alzheimer’s Disease presents insights into the state of art in AD research. Recent advancements in geroscience have led to the development of preventive medical strategies targeting aging, holding promise for reducing disease risk.
Research collaborations between academics, clinicians, and individuals with aphasia aim to bridge the digital divide and develop accessible technology. The special issue showcases innovative approaches to aphasia research, assessment, intervention, and participation.
A new screening tool, DuMAND Checklist, has shown promise for assessing neurobehavioral difficulties in children with Duchenne muscular dystrophy and improving quality of life. The checklist covers a range of issues including behavior, psychiatric disorders, and cognitive deficits.
Edith Brown Weiss advocates for a Planetary Trust to ensure a just and robust Earth system for present and future generations. She proposes six critical commitments for the UN Summit of the Future, including integrating the future into decision-making and practices.
A special section of WORK: A Journal of Prevention, Assessment & Rehabilitation highlights the varying physical elements and requirements for different occupations. PES frameworks are being developed for a range of physically active occupations to support personnel undertaking physically demanding tasks.
Researchers found a blood test to detect alpha-synuclein protein shows promise for diagnosing Parkinson's disease. The study, published in the Journal of Parkinson's Disease, confirmed that the biomarker is highly sensitive and changes over the course of the disease.
A special issue of WORK Journal explores the importance of designing healthy workplaces that address musculoskeletal conditions, burnout, and chronic pain. The issue highlights the need for an interdisciplinary approach integrating medical, psychological, and occupational therapies to prevent work-related illness and injury.
Dr. Rissman's research uses plasma Aβ42/Aβ40 ratio to predict brain amyloid PET positivity and identify individuals at risk for Alzheimer's disease. His findings demonstrate the potential of a blood test to screen for amyloid in preclinical AD trials.
A study of 221,777 individuals over 60 years old reveals disparities in antipsychotic use by socioeconomic status. People with low socioeconomic status are more likely to receive antipsychotics for dementia-related symptoms.
The study highlights the potential of omics research and AI tools to disentangle the molecular drivers of Alzheimer’s disease. Key findings include the identification of novel biomarkers for early detection and therapeutic targets, as well as the exploration of genetic factors contributing to AD risk and progression.
A special issue of the Journal of Pediatric Rehabilitation Medicine explores cerebral palsy beyond childhood, highlighting topics like mental health, sexuality, and independence in adults. The issue aims to address long-overlooked aspects of CP care, promoting a broader perspective for improved patient outcomes.
Research suggests that oxidative stress (OS) may trigger Alzheimer's disease and that enriching brain glutathione (GSH) could be a way forward. Clinical studies indicate GSH depletion in the hippocampus initiates early onset of AD prior to amyloid beta deposition and tau phosphorylation.
A study by Duke and Columbia Universities found that non-white older adults with mild cognitive impairment reside in areas with more environmental injustices than their white peers. The study suggests that location, race, and environmental factors may interact to impact brain health.
A new study investigates how various factors, including PTSD, influence cognitive functioning in Veterans aged 65 and older. The research suggests that certain screenings may miss underlying causes of cognitive decline, highlighting the need for comprehensive evaluations to guide treatment recommendations.
Climate change is exacerbating inequalities and insecurity among migrant women and girls, who account for 80% of all climate displacement. A new international legal framework is needed to address these issues and promote gender-sensitive policies and legislations.
A study in the Journal of Neuromuscular Diseases found that disease-modifying gene therapy treatments improve motor function, bulbar function, and pulmonary function in infants with spinal muscular atrophy. The real-world data from a large patient registry confirms improved safety profiles for early treatment opportunities.
Air pollution exposures are linked to increased risk of neurodegenerative diseases such as Alzheimer's and Parkinson's. The new PM2.5 standard may not be sufficient to mitigate these risks, especially for vulnerable populations.
The Workforce Innovation and Opportunity Act (WIOA) has improved pre-employment transition services (Pre-ETS) for students with disabilities, but challenges remain. Research highlights the need for targeted technical assistance, support, and innovation to improve outcomes.
The themed issue highlights advances in nosology, covert consciousness assessment, neuromedical morbidity, neurorehabilitation evaluation, and medicolegal challenges. Patients with severe brain injuries may have better prognoses than previously believed, but require careful assessment due to high misdiagnosis rates.
A narrative review article in NeuroRehabilitation addresses the medicolegal challenges of litigating cases involving patients with disorders of consciousness. Clinicians and neurolitigators must be aware of the nuances, including terminology, assessment, prognosis, treatment, and patient rights.
Research in Journal of Vocational Rehabilitation reveals that companies with inclusive values and committed leadership teams experience improved performance and positive employee perceptions. Disability initiatives also foster a cohesive culture, valuing disabled employees as a vital part of the workforce.
Researchers assess vamorolone's promise in treating Duchenne muscular dystrophy, finding similar efficacy to prednisone but some reduced adverse side effects. However, further investigation is needed on its cost and mechanisms of action.
The study found that participants in the LLC program used more preemployment transition services and vocational rehabilitation services, resulting in higher earnings. Demographic variation was minimal, with no significant differences in service uptake among groups.
A new study found that regular physical activity is related to increased size of brain areas important for memory and learning. The study looked at MRI brain scans from 10,125 people and found those who engaged in activities like walking, running, or sports had larger brain volumes in key areas.
A review article links pesticide exposure to an increased risk of developing Parkinson's disease through alterations in the gut microbiota. The authors recommend reducing or replacing agrochemicals and implementing coordinated efforts to develop standardized biomarkers for gut integrity and microbiome changes.
A new study published in the Journal of Vocational Rehabilitation found that Project SEARCH graduates with intellectual and developmental disabilities achieved high job retention rates (>77%) and overall satisfaction. However, challenges persist, including unmet ongoing support needs and limited follow-up services after graduation.
A recent study published in Journal of Vestibular Research found that Motorist Disorientation Syndrome (MDS) is not solely caused by vestibular dysfunction, but also related to visual dependency and anxiety. The research identified 18 patients with severe symptoms, leading to changes in driving habits for 17 of them.
A novel workflow has been developed to identify patients with 5q-SMA, a common type of spinal muscular atrophy, more accurately. The new approach uses a bioinformatics pipeline that masks the paralogous regions of the SMN1 gene, allowing for more precise detection of genetic variants.
The Journal of Pediatric Rehabilitation Medicine addresses the rising stressors causing mental health issues among healthcare professionals, including revenue generation, administrative issues, and patient satisfaction metrics. Physicians advocate for meaningful reforms, including adjustment of healthcare system expectations, cultural ...
The Human Right to Environment affirms the right to life itself, securing human health and wellbeing when humans protect nature. The recognition of this right drives governmental enforcement of environmental protection norms, requiring systemic change to address climate change, biodiversity loss, and pollution.
The journal highlights the complexities of neurological injury and neurodegenerative diseases, emphasizing virtual care as a potential solution. Identifying and treating neuropsychiatric symptoms is crucial for effective rehabilitation.
A special supplement presents insights on neurodegenerative diseases, including Alzheimer's and Parkinson's, affecting 55 million people worldwide. Researchers explore novel molecular pathways and therapeutic approaches, such as acupuncture therapy, to alleviate the burden of brain disorders.
The supplement to Journal of Pediatric Rehabilitation Medicine presents a compendium of abstracts from the 2023 World Congress on Spina Bifida Research and Care. The issue highlights the importance of international collaboration in addressing complex medical conditions like spina bifida.
The guidance paper outlines reliable methods and research practices for improving evidence syntheses. It emphasizes the need for proper education in methodology and cautions against relying solely on appraisal tools and software programs.
A special section of WORK journal provides insights into the overlap and differences between ME/CFS and Long COVID, highlighting the importance of early recognition of post-exertional malaise (PEM) for symptom management. Researchers emphasize the need for specialized care and pacing as a therapeutic strategy to improve quality of life.
A new special issue of the Journal of Huntington’s Disease highlights the critical impact of sleep dysfunction on HD patients. Disrupted sleep can alter metabolism, increase vulnerability to infection, and exacerbate disease outcomes.
Dr. Heather Sandison's study reveals significant improvements in cognitive function among individuals with cognitive decline after six months of a multimodal, individualized care plan. The study demonstrates the feasibility and impact of a holistic approach targeting various factors contributing to Alzheimer's disease progression.
A new study reveals a 12-week brain fitness program with coaching and lifestyle interventions improves patients' memory, attention, mood, and sleep. The program demonstrates significant improvements in cognitive function and reduces symptoms for ADHD, concussion, and memory loss patients.
Leading researchers discuss challenges associated with return to school for children and adolescents with TBI, highlighting the need for improved educator training and communication. Strategies for improving quality of life and outcomes are recommended by experts in this themed issue.
A special issue of the Journal of Pediatric Rehabilitation Medicine explores the treatment and management of cerebral palsy, including spasticity management and pain relief. The articles discuss various approaches to managing spasticity, such as enteral baclofen use and botulinum neurotoxinA injections, aiming to improve care and quali...
A case study published in the Journal of Alzheimer's Disease reveals that lecanemab can lead to therapy-induced Aβ phagocytosis and multifocal intracerebral hemorrhage, highlighting a potential risk of brain damage and death. The study suggests that better biomarkers are needed to assess the extent of cerebral amyloid angiopathy.
A special issue of the Journal of Vocational Rehabilitation presents strategies to challenge the status quo that young people with disabilities face in employment. Research highlights the need for verification of evidence-based practices, competitive integrated employment, and increased utilization of vocational rehabilitation services.
Research from Japan reveals higher risk of depression and anxiety among older adults with dementia and poor activity participation during the pandemic. Poor activity participation was also associated with high risk of depressive symptoms and anxiety.
Researchers found that COVID-19 infection leads to rapidly progressive dementia, blurring the lines between different types of dementia. Cortical atrophy and inflammation were key indicators, suggesting previously compromised brains have limited defense against new insults.
The unemployment rate for persons with disabilities in the US is more than double that of those without a disability, particularly youth. New research highlights the importance of community and business awareness of vocational services to increase work participation and quality of life.
Researchers propose incorporating 'hopamine' into therapeutic mix to personalize care for individuals with Parkinson's disease. By considering each person's unique physical and personal characteristics, healthcare professionals can avoid false hopes and create more effective treatment plans.
Research on caregiving after neurotrauma and neurological disability emphasizes the need to address unmet caregiver needs, which can impact the quality of care provided. Studies found that brain injury caregivers experience higher burden, decreased physical and neuropsychological functioning, and lower mental health.
Recent findings in spina bifida (SB) care highlight comorbidities such as autism and scoliosis, as well as the impact of COVID-19 on healthcare use. Telecommunication platforms like Zoom have evolved into clinical tools for SB care.
A study published in Journal of Neuromuscular Diseases demonstrates a positive effect of nusinersen treatment on motor function in ambulant pediatric and adult SMA patients. Clinically meaningful improvements in walking distance were observed in a subgroup of patients, with only five adult walkers showing a decline.