A recent study published in JAMA Network Open found that more than 70% of primary care physicians reported prescribing antibiotics to treat asymptomatic bacteria in urine tests, defying medical guidelines. This practice can lead to adverse health effects and contribute to antibiotic resistance.
Researchers at MIT City Science explore the impact of autonomy on shared micro-mobility systems, proposing it as a solution to mitigate challenges such as rebalancing and vehicle oversupply. An agent-based simulation tool assesses fleet performance and user experience, providing insights for informed decisions.
Researchers discovered a new species of beetle in the family Buprestidae that contributes to the production of red propolis. The beetle's larvae develop inside stems of a specific plant, and its resinous exudate is used by honey bees to make red propolis.
A study by Ohio State University researchers found that people learn from incidental exposure to new objects, making them ready to learn. Participants who were exposed to unfamiliar creatures earlier on learned the differences between them more quickly during explicit learning than those who received no prior exposure.
Researchers studied meiotic cohesin complexes' effect on chromosome structure and genomic integrity in embryonic stem cells. Maintaining adequate levels of REC8 and STAG3 factors ensures chromosomal stabilization and sister chromatid cohesion.
A recent study by the University of Cambridge found that autistic individuals have a higher risk of chronic mental and physical health conditions. They also report lower quality healthcare experiences, including difficulties with symptom description and sense overload.
Researchers at Simon Fraser University found that experiencing a balance-threatening physical consequence enhances motor learning and improves movement patterns for safer movement. This innovative approach could lead to effective therapies for individuals with neurological impairment.
Researchers at Yale University discovered a critical protein pair that maintains T cell quiescence, keeping immune systems healthy. Without this resting state, T cells die, making hosts more susceptible to infections and cancer.
A research team has developed a self-learning user stance embedding computational model to understand and predict online user stances and polarising views. The model aims to infer psychological foundations about individuals' values, personalities, attitudes, and moral judgments about contentious topics.
Researchers discovered that ancient retroviruses embedded in human genome can undergo retrotransposition into iPS cells, potentially posing a risk for regenerative medicine. The study found that HERV-K is expressed in SOX2-expressing cells and may cause cancer and neurological diseases by altering gene expression profiles.
Household catastrophic health care expenditures associated with chronic disease increased significantly from 2008 to 2018. Chronic diseases such as diabetes and heart disease led to substantial increases in healthcare costs, resulting in financial hardship for many households.
A new 'self-healing' anti-corrosion coating has been developed, which can repair microcracks and protect metal from erosion under solar irradiation. The coating's performance is verified to be maintained above 99% regardless of the repair, making it suitable for outdoor facilities.
An expert analysis of Russia's foreign policy statements since the USSR collapse finds Putin masking invasion policies with 1990s humanitarian propaganda. The study highlights how the Kremlin has used narratives from the 1990s to claim Russian minorities need protecting with military support.
Researchers found that care coordinators identifying illnesses early and providing timely care allowed most residents to 'age in place,' reducing need for nursing home care. Exercise and socialization opportunities also improved physical and mental health outcomes.
Researchers at MIT have designed a new type of photoredox catalyst that can be used to coat plastic tubing and perform chemical transformations on reactants as they flow through the tube. This breakthrough could enable the use of light-driven reactions in manufacturing processes, increasing efficiency and reducing waste.
The CPT theorem, a fundamental concept in quantum field theory, has its roots in the early 20th century revolution of quantum mechanics and relativity. The new paper reveals how this theorem's significance evolved over time, from being initially overlooked to becoming a cornerstone of modern physics.
Researchers found that circular RNA circCCNB1, derived from oncogene CCBN1, is downregulated in nasopharyngeal carcinoma (NPC) and inhibits cell migration and invasion. It does so by stabilizing TJP1 mRNA through interaction with NF90.
The Siberian tundra is projected to disappear entirely unless ambitious greenhouse-gas reduction measures are taken. A simulation shows that only 30% of the tundra can survive with aggressive climate protection, while the rest will be lost.
Researchers found that listening to groove music enhances executive function and activity in the brain's prefrontal cortex in familiarized participants. The study used functional near-infrared spectroscopy to measure changes in cognitive function before and after listening to music.
A study by Brazilian scientists reveals that autophagy can modulate the accumulation of mutant mitochondrial DNA in cells during aging. The researchers found that mice with liver-specific atg7 knockout showed reduced buildup of mutant DNA, suggesting a potential therapeutic target for diseases associated with mitochondrial DNA mutations.
Biologists at the University of Pennsylvania have discovered a two-sided genomic arms race between satellite DNA and its binding proteins in fruit flies. The study reveals that when these elements interact, significant costs to fitness can occur, including impacts on fertility and cancer development.
Researchers investigate how COVID-19 pandemic policies impacted access to life-saving treatment for opioid use disorder in minority groups. They aim to understand structural mechanisms of disparities and encourage the healthcare system to review and change social policies.
Researchers have developed novel sensors that can precisely measure dopamine levels in nerve cells, providing new insights into the mechanisms of dopamine release. The sensors use modified carbon nanotubes to visualise individual dopamine release events along neuronal structures.
Parents who used videoconferencing technology to view their hospitalized premature infant reported improved pumping experiences and increased bonding. The study found that videoconferencing strengthened the connection between families and their newborns, reducing stress and anxiety.
Follow-up data from the COSMIC-311 study confirm cabozantinib's superiority over placebo in patients with progressive differentiated thyroid cancer, with significant improvements in progression-free survival across all tumor subtypes. The treatment also demonstrated manageable safety and efficacy in a diverse patient population.
A new study from researchers at Dell Medical School found that providing caregivers with four weeks of free tastings of produce and grocery gift cards can lead to improvements in kids' diets. The study, published in JAMA Network Open, showed that children ate healthier foods two additional times per day compared to the control group.
The ECOG-ACRIN Cancer Research Group presented promising trial results at ASCO 2022, including an 8-year survival rate in the CHAARTED prostate trial. The research also explored outcomes by tobacco use in head and neck studies, shedding light on cancer treatment effectiveness.
A team of researchers at Singapore Management University is working on a project to identify polarizing topics and measure attitude strength using machine learning algorithms. The study aims to understand how opinion-based division can undermine social resilience, particularly in the digital age.
Researchers discovered nanoscale ordered/disordered domains in Fe3Pt alloys with enhanced lattice strain control. The work provides structural insights into chemical ordering at the atomic scale, enabling new lattice design strategies.
A meta-analysis published in The Lancet Oncology suggests that targeted radiation therapy, which spares healthy brain tissue, is equitable to whole brain radiation therapy for patients with small cell lung cancer and brain metastases. This approach may improve their care experience with fewer negative cognitive consequences.
A study by University of Alberta researchers found that language related to depression on social media did not increase in response to COVID-19 waves, but rather decreased as people adapted. Instead, they found spikes in language related to the Black Lives Matter movement and other global events.
A new AI method can distinguish between the overall sounds of healthy and unhealthy coral reefs, making it a valuable tool for monitoring reef health. The technique uses machine learning to analyze sound recordings and track the progress of reef restoration projects.
New research by Nicola Limodio finds that terrorist attacks are sensitive to local funding availability, with more attacks occurring in cities with higher funding. Financial counter-terrorism can be effective in limiting the ability of terrorist organizations to access funds.
Researchers studied microswimmers' dynamics under gravity, discovering how clusters form through a combination of gravity and hydrodynamic interactions. The team's simulations showed that two key ingredients – gravity and the strength of reorienting gravity torque – are sufficient for cluster formation.
Researchers at Memorial Sloan Kettering Cancer Center have identified a new subtype of prostate cancer that accounts for 30% of all cases. This stem cell-like subtype, characterized by specific gene expression patterns, is the second most prevalent group after androgen-sensitive type.
A team of researchers at Indian Institute of Science developed a record-breaking true random number generator (TRNG) that uses the random motion of electrons to generate secure random numbers. The device, which is more compact and faster than previous TRNGs, has exceeded NIST standards with a high min-entropy value of 0.98.
Dr. Björn Schumacher will discuss his research on genome stability and its impact on aging and disease, using C. elegans as a model organism. His work aims to contribute to the development of future strategies to prevent age-related diseases.
Researchers developed an algorithm to classify patients into disease subtypes based on molecular changes, enabling more targeted treatments. The tool has shown potential in a study on non-alcoholic fatty liver disease, identifying lipid biomarkers for disease progression.
A new study from the University of Illinois finds that wine tariffs imposed during trade disputes have substantial economic costs for producers and consumers. The study estimates that the U.S.-EU dispute cost $190 million in lost trade, while the China-Australia dispute cost $149 million annually.
Researchers at Kyoto University identify a distinct subpopulation of fibroblasts responsible for producing the hormone erythropoietin (Epo), which stimulates red blood cell production. This discovery provides insight into renal anemia and may lead to novel treatment methods for patients with chronic kidney disease.
Researchers uncover novel enzymatic transformation for carbon-carbon bond formation, enabling efficient bioproduction of bioactive compounds. The discovery paves the way for sustainable chemistry and comprehensive development of a new class of natural products.
The Collaborative Research Centre Hearing Acoustics is developing smart hearing aids that use artificial intelligence to adjust to different environments. The project, which aims to create more adaptable hearing devices, has received $8.1 million in funding for another four years.
Researchers at Newcastle University have discovered a new inherited condition, TULP3-related ciliopathy, which causes kidney and liver failure in children and adults. The study identified the faulty gene responsible for increased fibrosis in the liver and kidney, leading to organ failure.
Children previously infected with COVID-19 or MIS-C are not protected against the newer Omicron variant. However, vaccination shows protective effects, according to a study published in Nature Communications.
A comprehensive study by Hong Kong University of Science and Technology revealed that anthropogenic low-volatility organic vapors play a critical role in forming secondary organic aerosols (SOA) and haze pollution in urban environments. The research found that oxidation of VOCs dominates OOMs formation, with nitrogen oxides significant...
Researchers at University of Tokyo used machine learning-based analysis of scalp-recorded EEG to see when and where odors are processed in the brain. Unpleasant odors were found to be processed earlier than pleasant ones, suggesting potential early warning system against dangers.
A survey of plastic surgery residents found that high costs and inflexible work hours hinder access to childcare. Women residents are disproportionately affected, missing work more often due to childcare issues and considering leaving their programs.
A multi-disciplinary project aims to understand the science and practice of adaptability and resilience, particularly in the face of COVID-19 realities. The research team will develop an integrative framework and modeling tool to study how people adapt and thrive in rapidly evolving changes.
Researchers have developed a non-invasive method to visualize and quantify brain inflammation using diffusion-weighted magnetic resonance imaging (MRI). This breakthrough has significant implications for the diagnosis and treatment of neurodegenerative diseases such as Alzheimer's, Parkinson's, and multiple sclerosis.
Researchers have identified a previously unrecognized form of hormone therapy-resistant prostate cancer and found promising drug targets to treat it. The discovery opens the door to developing therapies that specifically target this disease, which accounts for approximately a quarter of castration-resistant prostate cancers.
A gene associated with Nascimento Syndrome triggers cells' defenses against environmental attacks by modifying proteins under stress. Rad6, a master regulator of this process, helps cells adapt to stressful conditions, shedding light on the disease's progression.
Researchers created oil-based gels that can deliver a variety of medications, including those for infectious diseases, in a stable and palatable form. The gels can be used to administer drugs to children and adults with difficulty swallowing pills, and could have a significant impact on improving medication adherence.
Researchers tested ictB transformants in field-grown tobacco and found no significant improvement in photosynthesis or biomass production. Despite previous studies suggesting potential benefits, the current study suggests that ictB overexpression may only be beneficial in controlled environments.
Researchers found a simple correspondence between interaction strength and statistics parameter in 1D and 2D quantum Bose gases in the quantum critical regime. This emergence of fractional exclusion statistics is confirmed through theoretical computations, numerical simulations, and experimental measurements.
A large US hospital study found that hospitals providing more registered nurse hours of care can decrease mortality rates in Medicare patients with sepsis. The analysis of over 702,000 patients suggests a strong association between nurse staffing and patient outcomes.
China's rural modernization policy seeks to revitalize rural economies by promoting entrepreneurship, new organisational forms, and increased commercialisation of agriculture. The goal is to raise rural income levels and reduce disparities with urban areas.
A recent study out of the Complexity Science Hub Vienna developed a mathematical and computational framework for analysing neural activity in C. elegans, a tiny worm used to study neural activity. The study proposes a way to unmask the roles of neurons by using more natural perturbations.
A Johns Hopkins University study found that microbial mats on Little Ambergris Cay regrew in just 10 months after Hurricane Irma's devastating impact. The discovery suggests these ecosystems may adapt to changing sea levels and stabilize under climate change.
Researchers from Brigham and Women's Hospital and MIT designed an oil-based gel system, oleogel, to deliver medications to children with swallowing difficulties. The system has been shown to be compatible with most drugs and can facilitate drug uptake at levels comparable to solid tablets.
A new analysis by Yale University researchers found that the US spends significantly more on cancer care than other high-income countries, yet its cancer mortality rates are only slightly better. The study suggests lax regulation of cancer drug approvals and pricing contribute to the high cost.
Astronomers used the Cosmic Evolution Survey to discover active supermassive black holes in distant galaxies. These findings suggest that a supermassive black hole can disrupt gas and prevent star formation, leading to the sudden end of galaxy star formation.
Researchers found that lab zebrafish have lost physiological plasticity, a characteristic that allows organisms to adjust to different environments, over time. This loss affects their ability to perform consistently across a wide range of temperatures, highlighting the costs of domestication.
Research investigates the effectiveness of different communication modes in negotiations, including video-conferencing, audio calls, text messaging, and face-to-face interaction. The study aims to identify key factors influencing negotiation outcomes, such as negotiator characteristics and conflict resolution styles.
The collaboration between public and private organizations has led to innovative applications in tourism and culture sectors. Visitors can interact with a humanoid robot and solve puzzles using Meta Quest visors connected to the 5G network, exploring artworks and moving virtual objects.
A new study by the University of Exeter predicts that the pink sea fan coral species will expand its range northwards along the British coast as global temperatures rise. The research found suitable habitat for the species beyond its current northern limits, indicating potential spread by 2100.
By using the shape of colloids, researchers can create building blocks for new materials with interesting properties. The study's findings show that the density of the structure can be lower than expected, leading to the possibility of creating strong but lightweight materials.
A new game called QuitBet is being tested to help people quit smoking by providing a fun and engaging way to adopt healthy habits. Players commit to quitting smoking over four weeks and bet $30, with winners typically doubling their money.
A recent study found that social media is a powerful tool for cities to communicate and collect information during emergencies. The research analyzed data from 23 Florida counties and their use of social media during Hurricane Irma, finding that many counties struggled with managing multiple social media accounts and correcting bad inf...
A study of 2.6 million Chicago residents found that zip codes with low vaccination rates had higher COVID-19 mortality rates during the Alpha and Delta waves. This inequitable coverage exacerbated existing racial and ethnic disparities in COVID-19 deaths.
Despite the US leading in cancer care spending, it doesn't show substantial lower cancer mortality rates compared to other high-income countries. Cancer care spending across 22 high-income countries reveals a lack of correlation with cancer-related mortality rates.
Researchers found that 63.2% of participants reported transformative experiences, feeling more socially connected and willing to share resources with strangers. These experiences persisted for at least six months and expanded the circle of generosity beyond family and friends.
New Cornell University research finds that women experience more frustration when praised for collaborative qualities than men, who are expected to be assertive. The study suggests that positive gender stereotypes can backfire and have negative emotional consequences for women in the workplace.
Chemists at Scripps Research unveil a new method for synthesizing diverse and complex lactones from cheap dicarboxylic acids. This breakthrough enables the creation of valuable molecules, such as natural antibiotics and fragrances.
A recent study on Reddit climate debates found little evidence of echo chambers, instead revealing a mix of polarized discussions and deliberate debate. The researchers analyzed over 18,000 posts and 267,000 comments from 93,850 users to examine topics, information sources, and community dynamics.
Research suggests that non-GAAP earnings reports can lead to a higher risk of stock price crashes due to information asymmetry and manipulation. Companies use non-GAAP earnings to present a more positive picture, but investors should be cautious when managers have an incentive to mislead them.
A new study suggests that wild animal populations can adapt more rapidly than scientists previously thought, thanks to a higher genetic contribution to differences in individual survival and reproduction. This rapid adaptation could aid species' odds of survival, but may be hindered by habitat loss and climate change.
ETRI showcases its 8K-UHD media service technology based on ATSC 3.0 standards, which enables seamless 8K-UHD broadcasting and 5G convergence. The technology includes MIMO-based 8K service technology, OTA/OTT converged 8K service technology, and 5G-MBMS broadcasting system.
A recent study by Durham University and Illinois Institute of Technology found that controlling message approaches can have negative effects on attitudes towards social distancing during the COVID-19 pandemic. In contrast, an autonomy-supportive approach was shown to lower feelings of defiance and increase positive motivation.