A follow-up study published in The Lancet Respiratory Medicine found that half of people hospitalized with COVID-19 have at least one symptom two years after infection. Long COVID symptoms persist, affecting quality of life, mental health, and healthcare use.
The new center aims to advance a groundbreaking combination of focused ultrasound and cancer immunotherapy, potentially revolutionizing cancer treatment. The partnership will focus on overcoming existing limitations of immunotherapy and expanding treatment options for various types of cancer.
A study published in Age and Ageing found that modifying lifestyle behaviors can have a marked effect on lifespan, particularly among older adults and those with chronic conditions. Adopting five or more healthy habits increased life expectancy by up to 6 years for healthy 40-year-olds.
Researchers investigated patterns of reported suicidal thoughts, planning, and behavior among firearm owners compared to non-owners. The study found a significant association between gun ownership and increased risk of suicidal thoughts and behaviors.
A team of international researchers has identified a genetic driver that improves yield traits in wheat while increasing protein content by up to 25 per cent. This discovery has the potential to generate new wheat varieties with higher quality grain.
A new study aims to assess the effectiveness of sun safety policies in primary schools in Wales. The project will examine what is currently being taught about sun safety and its impact on knowledge and behavior among children, teachers, staff, and school managers.
Researchers linked high mutation rates in children to errors in the biological father's sperm cells. Eight of 12 families with hypermutation were traced back to their fathers' chemotherapy treatments. These cases highlight the need for further investigation and potential measures, such as sperm freezing before treatment.
A team of researchers from Kumamoto University has developed a transformable polyrotaxane carrier that can facilitate genome editing using Cas9RNP with high efficiency. The carrier, called amino-PRX, is multi-step transformable and has low cytotoxicity, making it an enormously promising candidate for safe and efficient delivery.
A new study by NYU researchers found that neoliberal policies and institutions are associated with a preference for greater income inequality across over 160 countries. The analysis, which spanned 25 years (1995-2019), suggests that economic systems can shape human psychology to favor higher levels of income inequality.
Researchers found a link between long COVID and abnormal blood clotting markers, with participants experiencing reduced exercise capacity being four times more likely to have elevated markers. The study provides new insight into the potential mechanisms behind long COVID's longer-term effects.
Researchers revived photoreceptor cells in human macula, responding to bright and dim lights. The study restores communication between retinal cells, transforming brain and vision research.
Researchers have found blood proteins that cause migraine, including DKK1 and PDGFB, which inhibit Wnt signalling pathways. Lower levels of antioxidant proteins FARS2, GSTA4, and CHIC2 also contribute to inflammation linked to migraine. Therapies targeting increased DKK1 levels may represent novel tools for treatment.
Private companies like GlaxoSmithKline and Imperial College London have carried out high-risk breaches, handling sensitive patient data outside of agreed contracts. NHS Digital's audits show that many organisations have failed to protect patient confidentiality, with no consequences for those who breach agreements.
A receptor protein called insulin receptor is pivotal for brain stem cell longevity, according to a Rutgers study. The researchers also found that the same protein plays a crucial role in sustaining brain cancer cells.
A new study reveals that the introduction of domesticated sheep, goats, and cattle led to population growth, community cemeteries, and large monuments in ancient Mongolia. The adoption of ruminant livestock drove social changes on a long timescale.
A UC Davis study found a critical agent keeping KSHV dormant and undetected by the immune system. The virus is linked to various cancers and AIDS-related diseases. The researchers identified CHD4 as a key regulator of the latency-lytic switch, allowing the virus to stay silent.
The introduction of livestock and dairying to Bronze Age Mongolia may have driven social complexity, fostering the rise of complex societies. The spread of herds and horses into the Altai region had a significant impact on the development of these societies.
Whole genome sequences of ancient Uruguayan Indigenous people provide a genetic snapshot of populations before European military campaigns decimated them. The results support the theory of separate migrations into South America, contradicting the idea of a single Native American race across North and South America.
Dermatologists identify a possible link between acne and omega-3 fatty acids, finding that 94% of patients had below-recommended levels in their blood. A healthy diet rich in legumes and avoiding sunflower oil may help manage the condition. The study suggests that omega-3 supplements could be beneficial for treating acne.
Researchers study the sea-surface microlayer, a biogeochemical reactor where organisms adapt to harsh conditions like UV radiation and fluctuating temperatures. The team aims to understand biological, chemical, and physical interactions in this thin layer, influencing global climate.
A study of over 8 million adults in England found significant increases in neuropsychiatric illnesses after hospitalization for COVID-19 or other severe acute respiratory infections. Risks were similar for both conditions.
Research suggests that immigrants who prefer to stay in host countries develop valuable skills and social contacts, leading to better job prospects and increased economic contribution. Policymakers should consider location preferences and planned migration duration when designing immigration policies to maximize fiscal benefits.
Researchers modeled tumor evolution and found a tradeoff between growth advantage and immune evasion, suggesting certain mutations be ideal targets for precision immunotherapies. This could help prevent cancer emergence in people with inherited proclivity for malignancy.
A multidisciplinary panel of experts recommends avoiding repeat CTAP imaging and prioritizing opioid-minimizing pain control strategies for adults with low-risk, recurrent abdominal pain. The guidelines also suggest screening for depression and anxiety during ED evaluations.
Researchers identified genetic patterns in brain metastatic prostate cancer cells, revealing potential targets for PARP inhibitor therapy. This study contributes to precision medicine by tailoring treatment to individual patient profiles.
A new study found that rising income inequality in the US is associated with declining adult health, particularly among those who experienced childhood poverty. The research analyzed data from 1925 to 1999 and found a strong link between childhood inequality and adult markers of poor health.
Researchers are studying visual regions of the mouse brain as animals see and respond to different pictures or movies, with projects led by Vanderbilt University, UC Berkeley, and York University. The study aims to uncover how neurons react to optical illusions and how the brain interprets sensory information.
A low-cost ventilator prototype has been developed, making it accessible to all, including adults and children, with a potential price tag of USD $1500. The PVP1 project aims to provide a pressure-controlled ventilator research platform for compatible adult and pediatric uses.
Researchers at the University of Basel have discovered a promising therapeutic approach for estrogen-receptor-positive breast tumors with the GATA3 gene mutation. The approach involves inhibiting the MDM2 gene, which is sensitive to disruption in these cancer cells.
A joint research team investigated the generation of low-energy protons in dissociative ionization of H2 using time-energy-resolved spectroscopy. They found that low-energy protons are produced via dipole-transition at large bond lengths, contrary to the expected bond-softening scenario.
Researchers investigate the role of gut bacteria in pneumonia infection in the elderly, finding that a leaky gut can lead to inflamed lungs. The study suggests that aging compromises immune system control over bacteria, allowing them to migrate to other parts of the body and cause poor outcomes.
Researchers at Lund University found that improved ventilation and distance between patients significantly reduce airborne virus transmission. The study's findings aim to update international healthcare guidelines.
A study published in Med found that the human microbiome's variation explains different patient responses to statins. The researchers discovered a Bacteroides enriched microbiome with lower diversity was associated with stronger LDL-lowering effects but greater disruption of blood glucose levels.
A new study found that herpesvirus infection may contribute to impaired glucose metabolism and increase the risk of developing type 2 diabetes. Herpes simplex virus 2 (HSV2) and cytomegalovirus (CMV) were associated with an increased incidence of prediabetes and type 2 diabetes, independent of other risk factors.
Researchers discovered hundreds of new gene functions in algae, which have counterparts in plants, enabling better understanding of photosynthesis, DNA repair, and stress responses. The findings can improve biofuel production and develop heat-tolerant crops.
A field experiment in Bangladesh shows that the poor lack opportunities to gain wealth, but a one-time boost can make a major difference. The study suggests that poverty is not principally due to people's capabilities or attitudes, but rather an initial lack of resources prevents them from improving their circumstances.
A national study of over 170 pregnant women found rising exposure to potentially harmful chemicals from plastics and pesticides. Latinas had higher levels of parabens, phthalates, and bisphenols, which may be linked to increased risk during fetal development.
A new study by the University of Portsmouth found that investigators who asked suspects to multi-task during interviews were more likely to detect lies. Lie tellers struggled with secondary tasks, particularly those deemed important.
A recent study by Leipzig University researchers has identified a rare gene mutation that causes increased cognitive performance and blindness. The mutation affects synaptic communication, leading to improved neuronal function, as demonstrated using fruit flies.
A specialized limb in a mature male trilobite species sheds light on trilobite mating behaviors for the first time. The discovery, published in Geology, reveals that complex mating behaviors originated during the Cambrian Explosion over 500 million years ago.
Breast cancer cells accumulate intracellular lipid droplets in acidic environments, leading to poor outcomes and disease progression. Targeting the acid-sensing receptor OGR1 may inhibit stress responses and cell growth.
Researchers assessed metabolites in African savanna elephants for the first time, finding little variation among six healthy adults on the same diet. The study establishes a technique to accurately capture metabolites and provides insights into metabolism and health relationships in these endangered animals.
The new ASTRO guideline provides guidance on radiation therapy for brain metastases, including evidence-based recommendations for multidisciplinary planning and delivery of advanced techniques to manage intact and resected brain tumors. The guideline aims to improve quality of life and outcomes for patients with brain metastases.
Researchers discovered a link between traumatic brain injuries and changes in the gut microbiome, suggesting a potential diagnostic tool for concussions. The study found two bacterial species that dropped significantly after concussions, indicating a correlation with traumatic brain injury-linked proteins in the blood.
Researchers from ANU increased CO2 channels in tobacco plants to enhance photosynthesis, but found no significant impact. The study used computer modeling to predict how changes would affect mesophyll conductance.
Researchers have discovered that soil microbes use distinct metabolic pathways to metabolize carbon in different soils, challenging long-held assumptions in the field of soil ecology. The study suggests that these differences may be related to protection against oxygen stress in certain environments.
Researchers documented traditional wooden boats in the Zanzibar Channel, showing continued use despite modern transportation developments. The study highlights innovations such as outboard engines and portable generators, which have transformed fishing methods.
A recent study found that homeless US adolescents experience significantly worse mental health and more substance use than their housed peers. The burden of homelessness disproportionately affects black, Hispanic, and LGBTQIA+ individuals, highlighting the need for targeted interventions and policies to address structural injustices.
The US Preventive Services Task Force (USPSTF) recommends against routine screening for chronic obstructive pulmonary disease (COPD) in asymptomatic adults who do not recognize or report respiratory symptoms. This decision is based on a lack of evidence showing the benefit of screening in preventing future cardiovascular events.
Researchers have discovered a key role for mitochondrial proteins in controlling tumor cell growth and survival. By targeting these proteins, scientists hope to develop new therapies that can prevent or treat metastatic prostate cancer. The study's findings offer promising insights into the complex biology of cancer cells.
Researchers argue that national strategies ignore pandemic's early lessons on chronic diseases and their disproportionate impact on underserved populations. They recommend incorporating prevention and control of chronic diseases into existing policies.
A recent study published in Nature Communications found that healthy developing neurons promote metastatic behaviour in neuroblastoma cells. This discovery highlights the importance of understanding the unique developmental environment within which cancers of embryonic origin form.
The study reveals that the YWHAZ gene can alter neuronal development, leading to behavioral alterations in response to novelty. The team identified key neurotransmitter alterations involved in behavior and found that using fluoxetine and quinpirole can reduce social behavior alterations.
A Brazilian study found that inclusion of visually impaired individuals is crucial for effective disaster prevention policy. The research highlighted barriers to their participation and proposed solutions such as smartphone apps and education to mitigate vulnerability to environmental hazards.
A new machine-learning framework has been developed to improve the design of catalysts, which speed up chemical reactions. The approach analyzes the conversion of carbon monoxide to methanol using a copper-based catalyst and identifies key steps that need to be tweaked to increase productivity.
Researchers at Arizona State University have designed and constructed artificial membrane channels using DNA, allowing selective transport of ions, proteins, and cargo. The channels can be opened and closed with a lock and key mechanism, enabling diverse scientific domains such as biosensing and drug delivery applications.
Researchers have discovered three unique brain subtypes indicating high, medium, and low susceptibility to chronic pain and trauma symptoms in veterans. The study provides an objective measurement of pain and trauma susceptibility and could lead to targeted and personalized treatments.
The study found that gut microbiota releases membrane vesicles containing bacterial DNA, which triggers the cytosolic cGAS-STING-IFN-I axis to protect distal organs against viral infections. Antibiotic treatment impairs this ability, making mice more susceptible to viral infections.
A recent study published in Endocrinology found that exposure to a scream sound may lead to diminished ovarian reserve and decreased fertility in female rats. The researchers discovered that the scream sound reduced estrogen and Anti-Mullerian hormone levels, as well as the number and quality of eggs, resulting in smaller litters.
Scientists analyzing NASA's ICON mission data and ESA's Swarm satellites found that the Tonga volcano's eruption triggered hurricane-speed winds and unusual electric currents in the ionosphere. The extreme winds reached speeds of up to 450 mph, affecting the equatorial electrojet and causing a dramatic shift in its direction.