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Newly identified drug targets could open door for esophageal cancer therapeutics

Researchers at Case Western Reserve University have identified two molecular pathways that could lead to new treatments for esophageal cancer. By blocking the JNK and TGF-beta pathways, tumors can be slowed in growth and even regressed in mice. The study's findings suggest a new targeted therapeutic avenue for this deadly form of cancer.

SourceCase Western Reserve University·JournalGASTROENTEROLOGY·DateFeb 27, 2019

Advances in naturopathy research reported in new special issue of JACM

A new special issue of JACM reports on recent naturopathy research advancements, exploring the effectiveness of whole-foods-based nutrition education and traditional knowledge in naturopathic education. The studies collectively demonstrate the potential benefits of multimodal, whole-person approaches for chronic conditions.

SourceMary Ann Liebert, Inc./Genetic Engineering News·JournalThe Journal of Alternative and Complementary Medicine·DateFeb 20, 2019

Hailey Herleman receives Distinguished Early Career Contributions-Practice Award from SIOP

Dr. Hailey Herleman has made significant contributions to the practice of industrial-organizational psychology through her thought leadership, exceptional service to clients, and collaborative approach to applying analytics to workforce issues. She is a recipient of the Distinguished Early Career Contributions-Practice Award from SIOP.

The silence of sickle cell disease

A study led by John Wood, MD, PhD, finds that patients with sickle cell disease experience reduced oxygen delivery to the white matter of the brain, despite normal total oxygen delivery. This disparity leads to debilitating silent strokes with significant effects on executive function.

SourceChildren's Hospital Los Angeles·JournalAmerican Journal of Hematology·DateFeb 6, 2019

The interplay between relationships, stress, and sleep

A new study found that positive relationship experiences in early adulthood reduce stressful life events, leading to better sleep quality later in life. The research suggests relationships play a crucial role in reducing stress, which in turn affects health behaviors.

SourceWiley·JournalPersonal Relationships·DateFeb 6, 2019

Laughter may be best medicine -- for brain surgery

Researchers at Emory University discovered that electrical stimulation of the cingulum bundle can induce laughter and a sense of calm in patients undergoing brain surgery. The technique has potential applications in treating depression, anxiety disorders, and chronic pain via deep brain stimulation.

SourceEmory Health Sciences·JournalJournal of Clinical Investigation·DateFeb 4, 2019

Advocating for social issues at work more likely to succeed linking morality and mission, study says

A recent study published by the American Psychological Association found that employees who frame their arguments in moral language are more successful in getting buy-in from management when the issue aligns with the company's values and mission. The study suggests that using moral language without explicit links to the organization's ...

SourceAmerican Psychological Association·JournalJournal of Applied Psychology·DateFeb 4, 2019

Persistent low body weight in young kids increases risk for anorexia nervosa later

A new study found that persistent low body mass index (BMI) in children starting as young as age 2 for boys and 4 for girls may increase the risk of developing anorexia nervosa later. Persistent high BMI in childhood also increases the risk of other eating disorders such as bulimia nervosa, binge-eating disorder, and purging disorder.

SourceUniversity of North Carolina Health Care·JournalJournal of the American Academy of Child & Adolescent Psychiatry·DateJan 31, 2019

Fruit and vegetable consumption linked to lower risk of early death for dialysis patients

A new study found that higher consumption of fruits and vegetables may be associated with a lower risk of premature death in patients undergoing maintenance hemodialysis. The findings suggest that more studies are needed to fine-tune dietary recommendations for patients with kidney failure.

SourceAmerican Society of Nephrology·JournalClinical Journal of the American Society of Nephrology·DateJan 31, 2019

E-cigarettes more effective than nicotine replacement therapies, finds major trial

A clinical trial found e-cigarettes to be almost twice as effective as nicotine replacement treatments in helping smokers quit. The study, funded by the National Institute for Health Research, involved 886 smokers and found that e-cigarette users were more likely to achieve abstinence and experience a reduction in smoking urges.

SourceQueen Mary University of London·JournalNew England Journal of Medicine·DateJan 30, 2019

Researchers identify high-risk areas for infant deaths in Harris County

A study by UTHealth researchers identified three high-risk areas in Harris County where SUID cases are most likely to occur. Modifiable risk factors included unsafe co-sleeping, improper sleep position, and tobacco use. The study suggests that following the American Academy of Pediatrics' recommendations can reduce SUID incidence.

SourceUniversity of Texas Health Science Center at Houston·JournalAmerican Journal of Forensic Medicine & Pathology·DateJan 30, 2019