News on doctoral training and the researchers it produces. Covers PhD and fellowship programs, physician-scientist training, and major training investments.
A team of researchers developed the Integrated Intervention for Dual Problems and Early Action (IIDEA) program to provide culturally tailored care for Latino immigrants. The study found that IIDEA reduced mental health symptoms but did not show an effect on alcohol and drug outcomes for participants with mild symptoms.
Researchers have identified a surprising role for brain cells in controlling bone density, suggesting a new approach to preventing osteoporosis. Blocking estrogen signals in the brain causes female mice to build extraordinarily strong bones and maintain them into old age.
Researchers found that HIV protein Nef disrupts T cell migration, initially slowing viral spread but later aiding viral survival by evading the immune response. The 'hydrophobic patch' of Nef enhances viral persistence.
Research found that 75% of older adults had at least one symptom, with nearly half having two or more. Symptoms increased with age, education level, and chronic conditions, leading to weaker grip strength, slower walking, and increased falls and hospitalizations risk.
Researchers found that patients with biochemical hypoglycemia are at increased risk of severe hypoglycemic events. The study analyzed the DCCT data set and used two levels of biochemical hypoglycemia to determine the relationship to severe hypoglycemic events.
Alison Weiss awarded grant to study Shiga toxin producing Escherichia coli 0157:H7, also known as Hamburger E. coli, which causes bloody diarrhea and kidney failure. Her lab will use human intestinal tissue models to test potential treatments.
Researchers studied genetically modified mice with neurofibromatosis type 1 (NF1), a condition associated with sleep problems. The mice exhibited fragmented and irregular sleep patterns, similar to people with NF1. This study could help identify molecular mechanisms underlying sleep disturbances in humans.
John Tilton will receive funding to develop a nanoPOD platform to deliver therapies to specific tissues in mice affected by genetic disease. The project aims to address the challenge of delivering nanoscale therapeutics to the right location inside the body.
Universal screening of individual blood donations for Zika virus is not cost-effective in the 50 US states during the first year. Screening was only cost-effective in high mosquito season in Puerto Rico, and finding suggests revisiting universal blood screening policy.
Research by the American Psychological Association found that whites and non-black minorities have difficulty distinguishing genuine from fake smiles on black faces, which can lead to negative outcomes in interracial interactions. The study suggests that this bias may be related to reluctance to make eye contact with black faces.
A new study found that younger enrollees and those without chronic conditions were more likely to not purchase insurance if there was no penalty. In California, the lack of a penalty led to an estimated 4-7% increase in monthly premium prices.
Researchers at UNC School of Medicine and Notre Dame University have coined a new term 'in fimo' for the experimental examination of excrement, derived from the Latin root laetus meaning fertile or happy. The study aims to improve scientific accuracy in discussing gut bacteria and their role in human health.
The Mark Foundation has awarded grants to eight promising early career scientists pursuing innovative projects in cancer risk prediction, prevention, detection, and treatment. The recipients aim to tackle diverse areas of basic, translational, and early clinical cancer research.
Researchers at Drexel University have discovered a buckling phenomenon in layered materials when subjected to pressure, which could revolutionize the way we study deformation. The 'ripplocations' observed in experiments with cards and metals demonstrate non-linear elastic behavior that precedes material failure.
A team of neuroscientists and engineers has developed a tiny, implantable device that can detect overactivity in the bladder and use light to tamp down the urge to urinate. The device works in laboratory rats and may one day help people with incontinence or frequent urination needs.
A study of 3003 African-American adults found that consuming a pattern of soda, sweetened fruit drinks, and water was associated with a higher risk of developing chronic kidney disease. The researchers were surprised to see that water as part of this beverage pattern was linked to a higher risk of CKD.
Researchers at Mount Sinai have discovered a novel combination of drugs that induces the highest rate of proliferation in adult human beta cells, increasing insulin production and potentially treating diabetes. The study found a 5-8% daily growth rate, which is significant progress toward a cure for the disease.
Fossils of well-armed and substantial flying reptiles from the UK's Jurassic period have been uncovered, revealing multiple pterosaur lineages, including a new species with a wingspan of two metres. The research sheds light on the evolution of flying reptiles and their role in understanding global natural history.
A study found that peritoneal dialysis clinical trials frequently disregard the most important outcomes for patients and caregivers. The researchers conducted focus groups with 81 patients and 45 caregivers from Australia, the US, and Hong Kong to identify their top priorities.
A study published by the American Psychological Association found that people with lower incomes who practice cognitive reappraisal strategies experience reduced anxiety levels. The researchers analyzed data from experiments and a national survey to understand how socioeconomic status affects emotional regulation strategies.
A new study found that certain neurons protect themselves from Alzheimer's by clearing toxic tau proteins, which accumulate in sluggish cells. The discovery suggests new treatment possibilities to support natural defense mechanisms against neurodegenerative diseases.
A large Kaiser Permanente study shows that 10 years after a negative colonoscopy, members had a 46% lower risk of developing colorectal cancer and an 88% lower risk of dying from it. This evidence supports the recommended 10-year rescreening interval after a normal colonoscopy finding.
A new study found that most nurses rate hospital end-of-life care unfavorably due to painful procedures and lack of teamwork. However, effective nurse-physician collaboration and manageable workloads can improve care quality.
A new study examines dialysis reimbursement policies worldwide, revealing significant disparities in access to care. The research suggests that high-income countries spend more on dialysis but have a lower percentage of healthcare budget allocated to it compared to low- and middle-income countries.
Researchers at the University of Arizona have identified the biological process behind pontocerebellar hypoplasia type Ib, a deadly disease affecting infants. They believe their discovery could lead to the development of a drug to stop the disease progression and improve treatment options.
The Harrington Discovery Institute has awarded over $700,000 to 10 US scientists for their innovative medical research. These scholars will support the commercialization of their work and have access to expertise and oversight in all aspects of drug development.
Researchers found that breastfeeding and family history of breast cancer had no impact on the increased risk. Risk peaked five years after childbirth, with a 80% higher risk compared to childfree women, but decreased by age 50. The study could inform screening decisions and prevention strategies.
Researchers conduct experiments with manmade lava to shed light on lava-water interactions, which can generate explosive eruptions. The study aims to improve scientists' ability to assess volcanic eruption risks.
Researchers have found that Botryllus schlosseri, a marine invertebrate, has a blood-forming system with uncanny similarities to humans. This discovery may provide a way to improve immune function and find new tools for biological discovery. The study also reveals parallels between the blood systems in Botryllus and mammals.
A CWRU researcher has secured a $14.6 million grant to study Alzheimer's disease in diverse populations, including African-Americans and Hispanics. The project aims to identify new genetic factors and improve understanding of the disease's impact on these communities.
A new study from the University at Buffalo found that U.S. Army Reserve and National Guard soldiers who experience greater feelings of guilt and other negative emotions about never having been deployed are more likely to misuse alcohol. The study, which examined data from Operation: SAFETY, a longitudinal study of the health and well-b...
Researchers found that stimulating the lateral orbitofrontal cortex (OFC) improved mood in patients with moderate to severe depression. The study suggests that OFC stimulation may help individuals experience a naturally positive mood state, removing an impediment to positive mood common in people with depression.
Researchers at UTHealth received grants to study the role of photoreceptors in sight and day/night vision. They aim to develop new therapeutic strategies for degenerative retinal diseases.
A recent study found that the prevalence of metabolic health among American adults is very low, even among those with normal weight. The researchers estimated that only about 12% of Americans meet the criteria for optimal metabolic health using more rigorous guidelines.
Researchers identified a cell type responsible for initial steps of adhesion formation and developed an antibody-based therapy to treat and prevent adhesions. The treatment showed promise in mouse models and expressed similar genes as human tissue, suggesting potential translation into the clinic.
A team of researchers at NYU Langone Health has successfully regrown hair strands on damaged skin by stimulating fibroblasts to secrete collagen through the sonic hedgehog signaling pathway. The study offers new hope for treating hair loss and may lead to the development of more effective drugs.
Researchers discovered that small, spherical mitochondria inside brain cells help neurons grow and form proper connections. This unique shape is tied to the neuron's shape and allows for optimal calcium uptake, driving healthy axonal growth and cellular communication.
Scientists at the University of Maryland School of Medicine discovered changes in brain activity linked to the brain's reward memory response in depression. The research found that the strength of signals between two brain regions is critical for processing rewarding stimuli.
A new study by the American Psychological Association finds that men with sexist attitudes may underestimate their power in relationships, leading to more aggressive behavior. The research suggests that this can create a vicious cycle, reinforcing stereotypes and damaging relationships.
Researchers found that between 25-60% of young people with psychotic experiences would not have developed them without childhood trauma. The study used the Bristol Children of the 90s longitudinal data, examining 4,433 participants at age 18.
A comprehensive analysis found a strong inverse relationship between vaping and smoking among youth and young adults. Vaping became more popular around 2014, resulting in accelerated reductions in youth and young adult smoking prevalence.
Researchers at UMass Medical School developed an siRNA therapy that reduces circulating sFLT1 levels and normalizes blood pressure and proteinuria in pregnant mice. The therapy shows promise as a potential strategy for treating preeclampsia in humans, but further studies are needed to optimize safety and efficacy.
The Bloomberg American Health Initiative releases a special supplement to Public Health Reports addressing five urgent US health challenges. The supplement features articles and commentaries on addiction and overdose, violence, obesity and the food system, environmental challenges, and adolescent health.
The century-old Wisconsin train car has been digitally accessed through 3D models and printed spare parts created using digital photogrammetry and terrestrial laser scanning. The project, led by the University of South Florida, aims to preserve the fragile antique components while allowing for future restoration efforts.
A new study by University of Waterloo researchers finds that high carbon emissions can lead to stock price depreciation and asset devaluation. Companies in emission-intensive sectors may experience fundamental devaluations in their stocks within 10 years, due to stricter environmental regulations and climate change risks.
Researchers have found a new therapeutic target for pancreatic cancer, RIP1 Kinase, which can be used in combination with other immune-boosting therapies to increase survival rates. The study shows that the drug GSK547 helps to mount a more aggressive attack against tumor cells, doubling survival to 50 days in mice.
A study by CU Anschutz found a significant association between prescribed access to psychotropic drugs and their use in attempted suicides. The researchers investigated 27,876 people who attempted suicide at least once and found that 70% of those using psychotropic drugs had prescribed access.
A UCSF study found that community choir participation reduced loneliness and increased interest in life among older adults, but did not improve cognition or physical function. The program, Community of Voices, engaged adults aged 60+ cognitively, physically, and socially through weekly group choir sessions.
Women who participate in breast screening have a significantly lower risk of dying from breast cancer within 10 and 20 years after diagnosis. The study found that screening detects cancers at an earlier stage, allowing for more effective treatment and a reduced mortality rate.
A new study has identified a common pattern of brain activity linked to feelings of low mood and anxiety, particularly in individuals with a tendency towards depression. The findings could serve as a biomarker for developing new therapies to treat mood disorders.
A new study reveals that patients with untreated hearing loss incur significantly higher total health care costs over time, totaling $22,434 per person over a decade. The study found that older adults with untreated hearing loss generated nearly 46% more in total health care costs compared to those without hearing loss.
A new decision support tool, DIRECT CDS, has been developed to optimize post-acute care (PAC) referrals and improve patient outcomes. The algorithm helps clinicians identify patients most in need of PAC and suggests the level of care required.
A Columbia-led team has been awarded $16.75 million from the BRAIN Initiative to study the primary visual cortex, a region crucial for making sense of visual information. The five-year project aims to bridge the gap in knowledge between theoretical and experimental neuroscience.
A team at Brigham and Women's Hospital has developed a machine learning model that can accurately predict insertions and deletions caused by CRISPR-Cas9. In experiments, the approach corrected mutations in human cell lines for three diseases with high efficiency.
Research published by the American Psychological Association reveals that African-American job candidates receive lower salaries when evaluators believe they have negotiated too much. Racially biased individuals often hold negative stereotypes about African-American job seekers as less qualified or motivated than white applicants.
William Muñoz has been awarded the Nemko Prize for his innovative method of recording cortical neurons, which allows scientists to examine the functional architecture of the cortex in awake, behaving mice. His work reveals a new mechanism by which the cerebral cortex processes and integrates information.
Researchers found significant reductions in PTSD symptoms and increases in self-compassion among veterans who participated in the Dogs2Vets program. The 12-month study showed veterans experienced lower levels of perceived stress, isolation, and self-judgment.
A new study published in Health Affairs highlights the importance of improving nurse work environments and adequate staffing in reducing patient harm. Hospitals that implemented these changes saw significant improvements in patient safety indicators, while those that didn't experienced worsening care environments.
Erik Herzog and Gönül Peker received the Award for Education in Neuroscience from the Society for Neuroscience. Herzog is recognized for his efforts to increase diversity in neuroscience through mentoring and outreach, while Peker has promoted international educational experiences and research collaborations.
Research published by the American Psychological Association found that people with positive childhood memories tend to have better health, less depression, and fewer chronic illnesses as older adults. Good memories from childhood relationships with both mothers and fathers can reduce stress and promote healthy choices.