Articles tagged with Chronic Stress
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A recent study revealed the importance of Cav3.1-driven burst firing in the ventromedial hypothalamic nuclei in controlling anxiety-like behavior and energy expenditure following chronic stress. Enhanced burst firing was correlated with increased anxiety-like behavior, reduced food intake, and decreased energy expenditure.
A recent study by Oregon State University found that night shift nurses are more likely to suffer from poor sleep, PTSD, depression, anxiety, and inflammation. The researchers also discovered a significant disparity in sleep quality among Black nurses, highlighting the impact of systemic racism on their health.
UC researchers received a $1.2 million grant to examine the impact of stress hormone receptors on cell degeneration in Parkinson's disease. The study aims to develop a new model that better replicates the progression of the disease, which may lead to treatments targeting stress hormone blockers or next-generation therapeutics.
Researchers at West Virginia University are investigating the link between chronic stress and Alzheimer's disease using animal models. They aim to understand how xanthine oxidase may sabotage brain blood vessels in Alzheimer's patients, and explore whether a medication can block this pathway to keep the brain healthy.
Researchers found gender-specific brain alterations in people with depression, including altered blood-brain barriers in women. They also identified a potential depression biomarker in women's blood samples.
A study found that meditation training reduced chronic stress by 25% through decreased cortisol levels in hair. The researchers used a 9-month training programme to measure the effect, and the results showed that only sufficiently long training leads to significant stress-reducing effects.
A study found that chronic stress, measured by allostatic load, was associated with a lower likelihood of completing chemotherapy and lower overall survival rate in patients with lymph node-positive or high-risk lymph node-negative HER2-negative breast cancer. Allostatic load may be a better predictor than genetic ancestry for chemothe...
Researchers at Tokyo University of Science discover that vicarious social defeat can cause psychological stress in mice, leading to depression and decreased neurogenesis. The study sheds light on the pathophysiology of depression and may lead to the development of novel antidepressants.
Researchers Altaf Engineer and Esther Sternberg aim to redesign office spaces to enhance employees' emotional and physical health. Their seven-domain framework considers factors like sleep, movement, environment, and nutrition to create a healing space.
A study by Georgia State University researchers found a significant increase in physical and psychological aggression among couples during the pandemic. Rates of aggression rose sharply after shelter-in-place restrictions were implemented, with non-heavy drinkers being disproportionately affected.
New research has identified key genes that glucocorticoid hormones interact with in the hippocampus, a region crucial for stress coping and learning. The findings may lead to more effective strategies in preventing and treating mental health disorders.
A long-term study on wild chimpanzees found that young orphaned chimps experience high levels of stress when their mothers die, but this stress subsides over time. Adult orphaned chimps are supported by other chimps, which may contribute to their recovery from maternal loss.
A new multi-decadal study involving 242 wild female baboons found evidence to support chronic stress as a significant factor affecting survival. High stress levels throughout adult life were linked to shorter lifespans, with females experiencing a loss of 5.4 years of life compared to those with lower stress responses.
Researchers discover that a small group of neurons in the brain play a crucial role in depression. Chronic stress alters their function, leading to depressive behavior. Stimulation of these neurons reverses symptoms, suggesting a promising new approach to treating depression.
Scientists at the Weizmann Institute of Science mapped the entire stress axis in detail, identifying 21,723 cells along the route. They found significant alterations in gene expression and cell changes, particularly in the adrenal glands, which play a crucial role in the stress response.
A NYU Abu Dhabi study found that abnormal sleep architecture can predict stress vulnerability in mice. The research used an animal model to demonstrate how disrupted NREM sleep results in increased susceptibility to future stress.
Researchers used zebrafish to study the effects of chronic stress, finding that it can lead to anxiety-like conditions and serotonin metabolism deficits. The study suggests that zebrafish can be a valuable translational model for researching complex neurobiological conditions.
Researchers at GW University are investigating changes in the ventral tegmental area of the brain during chronic stress, a common contributor to depression and anxiety disorders. The study aims to understand how stress affects the reward circuitry and identify potential treatments.
Researchers at Florida Atlantic University and The Ohio State University identify the specific brain circuit responsible for neuroinflammation and psychological disorders caused by chronic stress. By limiting inflammatory signaling to this circuit, they suggest a potential treatment approach for anxiety and depression.
A study by North Dakota State University and HSE University found a positive correlation between Russian's latent dissent at work and emotional burnout. Employees often express dissent through venting to co-workers or friends rather than management, leading to burnout and work-life imbalance.
Researchers found that rats susceptible to depression had more serotonin neurons after chronic stress, but these effects could be reversed through amygdala activation. In contrast, resilient rats showed no significant change in serotonin levels under stressful conditions.
Researchers exploring how chronic stress impacts brain function and increases risk of depression, finding link to complement system and inflammation in prefrontal cortex. Chronic stress may instigate destructive cycle leading to depression through immune response and inflammation.
A study published by Professor Henrik Oster suggests that daily stress coupled with a disrupted internal clock increases the risk of developing metabolic disorders such as obesity and type 2 diabetes. This is because environmental stress can affect food intake, promote weight gain, and have long-lasting effects on stress responses.
Researchers found a strong association between chronic stress and hypertension in African Americans, with those reporting high stress levels facing a 22% increased risk over time. Lifestyle changes may help prevent hypertension, but culturally sensitive interventions are needed to address disparities.
A recent study has found that chronic stress can lead to changes in the mitochondria of brain cells, which may contribute to anxiety symptoms. Researchers identified differences in mitochondrial pathways between stressed and non-stressed mice and patients with panic disorder.
Cardiac rehabilitation programmes have a positive impact on patients over 60 years old, improving their ability to exercise and reducing anxiety. After a few sessions, patients become more confident and have improved attitudes towards physical activity.
Researchers found that chronic stress can harm ovarian function and reduce the number of primordial follicles, but blocking ghrelin receptor improved ovarian function. The study suggests that eating habits may be able to mitigate the effects of stress on fertility.
A new study reveals that chronic stress promotes breast cancer growth and spread by activating a biochemical pathway involving the stress hormone epinephrine. Vitamin C has been identified as a potential therapeutic agent to target this pathway, potentially offering new hope for patients undergoing chronic stress.
Researchers developed a flexible electrode to monitor adrenal gland activity in real-time, providing potential continuous tracking of acute and chronic stress responses. This method could aid in diagnosis and treatment of stress disorders.
Researchers found that teens who used cognitive reappraisal had better metabolic measures, while those who suppressed emotions had more inflammation. The study suggests that emotion regulation strategies developed in adolescence can affect health later in life.
A new study from Ohio State University suggests that childhood stress can contribute to mood disorders later in life by altering brain development through mast cell activity. Chronic stress was found to increase mast cell activity in the brain of stressed rats.
Research reveals chronic stress impairs spatial memory through altered glucose metabolism, with susceptible individuals showing cognitive impairments.
A mindfulness-based program reduced chronic stress and depressive symptoms in infertile women, improving general well-being. The study found a significant decrease in stress symptoms after the intervention, with no change in the control group.
A recent study published in the American Journal of Human Biology found that healthy gaming experiences are linked to favorable gene expression profiles. The research, led by Dr. Jeffrey Snodgrass, highlights the importance of social connectedness in mitigating negative effects of online gaming.
Researchers found African Americans and Latinos had higher levels of chronic stress and unhealthy behaviors, increasing their risk for depression. However, engaging in unhealthy behaviors did not increase depression risk in African Americans but rather reduced it due to chronic stress.
A Massachusetts General Hospital-led study reveals that chronic early-life stress raises PTSD vulnerability by increasing ghrelin levels in both rat models and human adolescents. Elevated ghrelin levels are associated with increased fear response and susceptibility to mental health disorders.
Researchers at TSRI have discovered that individuals with high levels of the enigmatic receptor GPR158 may be more susceptible to depression following chronic stress. This finding provides a potential clue to why some people are more resilient against mental illness, and offers a new target for developing effective treatments.
A new study by Brigham Young University finds that running under stress protects the hippocampus, a part of the brain responsible for learning and memory. Exercise strengthens synapses, maintaining long-term potentiation levels, which are essential for optimal memory formation and recall.
Researchers found that stressed animals chose high-risk options despite increased costs, and restored normal behavior by manipulating the prefronto-striosome circuit. This study suggests a potential method for treating disorders like depression and addiction.
A recent study discovered that cortisol levels in horses showing signs of compromised welfare were lower than those without such issues. This challenges the conventional view of cortisol as a sole indicator of stress and highlights the need for alternative measures to assess equine welfare.
Researchers studied health effects of job transition on employed vs unemployed adults, finding that poor quality work was linked to higher chronic stress biomarkers and worse physical health. Good quality work, however, was associated with improved mental health scores.
Researchers found that social rank triggers differential vulnerability to chronic stress and identifies brain energy metabolism as a predictive biomarker. The study showed that dominant mice display susceptibility to stress through social avoidance, while subordinate mice exhibit resilience.
A closed-loop acoustic stimulation brainwave technology significantly reduced symptoms of post-traumatic stress disorder (PTSD) in a small pilot study. The intervention, high-resolution relational resonance-based electroencephalic mirroring (HIRREM), showed a 89% decrease in symptoms and improved balance in brain pattern activity.
New research suggests that captive meerkat groups in zoos are more susceptible to chronic stress due to their small group sizes and constant exposure to human visitors. The study measured stress levels by analyzing hormone samples from the meerkats' droppings, revealing a link between small group sizes and high visitor numbers.
Researchers discovered a separate mechanism in the brain that deals only with chronic stress, involving a small group of nerve cells in the paraventricular nucleus. The CRFR1 system is thought to play a role in regulating cortisol levels and may be involved in depression, with patients having more of this receptor than average.
Childhood bullying may lead to an increased risk of chronic stress exposure, which can contribute to the development of diseases such as depression, diabetes, and heart disease. Early-life stress exposure can also affect physiological systems' response to future stressors through epigenetic changes.
Research reveals that a brief period of stress can cause the hippocampus to start shrinking, which precedes the onset of memory loss. The study found that stressed rats performed poorly in memory tests compared to unstressed rats, with individual differences in brain shrinkage predicting worse performance.
Research from Binghamton University found that adolescent alcohol exposure can lead to a lack of hormonal stress adaptation, making adults more vulnerable to chronic stress. Adult males exposed to alcohol during adolescence showed elevated cortisol levels and impaired stress response.
A recent study by the UCLA-led research team found that women with impaired cortisol levels before pregnancy are more likely to give birth to lower-weight babies. Elevated maternal cortisol can deprive the fetus of oxygen and nutrients, leading to lower birth weight and increased risk of infant mortality.
A scientific review paper warns that chronic stress and anxiety can damage the brain's hippocampus and prefrontal cortex, increasing the risk of developing depression and dementia. Anti-depressant treatment and physical activity have been found to increase neurogenesis and may not be completely irreversible.
A Yale team discovered that a high-fat diet can disrupt pathways involved in synaptic plasticity and metabolism, leading to depression-like symptoms. Ketamine reverses these effects, suggesting a potential solution for treating depression associated with metabolic disorders.
A new study reveals that adverse childhood experiences can heighten a woman's risk of preterm birth, with the risk doubling if two or more events occur. Researchers hope to develop early interventions and predict which women are at risk of preterm birth.
Women under chronic stress have significantly lower levels of klotho, a hormone that regulates aging and enhances cognition. The study found even lower levels of klotho in women with clinically significant depressive symptoms, suggesting a link between psychological influences and klotho.
A new study published in the Journal of Gerontology: Psychological Sciences found that mortality and blood pressure are directly linked to relationship quality. The research revealed that wives' stress has significant implications for husbands' blood pressure, particularly in negative relationships.
Researchers at UC Berkeley discovered that chronic stress activates a hormone reducing fertility long after stress ends, and blocking this hormone restores female reproductive behavior to normal in rats. The study's findings suggest the potential for a gene therapy approach to help women overcome infertility caused by stress.
A genetic study suggests that individuals with a specific genotype may be prone to weight gain and increased risk of diabetes and heart disease when exposed to chronic stress. Simple interventions like healthy diet, exercise, and stress management could help reduce the risk of cardiovascular disease in these individuals.
Researchers at Concordia University found that individuals with less variable heart rates when worrying are more likely to experience high stress levels later on. This diagnostic measure can help healthcare professionals identify those most susceptible to chronic stress and provide timely interventions.
A team from EPFL Brain Mind Institute finds that chronic stress activates an enzyme that reduces nectin-3 cell adhesion proteins, leading to social skills loss and impaired memory. External treatments can restore sociability and normal cognitive skills.
Research found that higher levels of stress, depressive symptoms, and hostility are associated with a significantly increased risk of stroke or transient ischemic attack (TIA) in middle-age and older adults. The study used data from the Multi-Ethnic Study of Atherosclerosis and found that individuals with the highest scores for these p...
Researchers found that chronically stressed women who consume high-fat, high-sugar foods are more prone to metabolic risks such as increased waistlines, insulin resistance, and oxidative damage. The study suggests a stress pathway that influences biology through diet, highlighting the importance of treating chronic stress.