Researchers at Brandeis University have pinpointed a genetic repressor that can transform diphtheria into a lethal parasite. The discovery could lead to a novel class of antibiotics that prevent bacterial virulence without inducing resistance.
University of North Carolina at Chapel Hill scientists have discovered that over-expressing a special gene in tobacco plants can manipulate the size of individual cells, resulting in smaller plant crops more resistant to dry or wet conditions. This breakthrough could lead to controlled wood cell sizes for various applications.
Researchers at UT Southwestern Medical Center have discovered how aspirin reduces inflammation by targeting a specific kinase. Aspirin inhibition prevents NF-kB activation and suppresses inflammation, making it an excellent target for developing novel anti-inflammatory agents.
Bernard Roizman's research has laid the groundwork for current efforts to develop a vaccine against HSV and gene therapies. He identified essential genes in viral replication, including a protease enzyme targeted by pharmaceutical companies.
Duke University chemists have developed novel liquid polymers that can be solidified by laser light to seal transplanted insulin-producing cells inside a selectively permeable capsule. The microcapsules reduce excessive blood sugar levels in experimental diabetic rats for up to eight days.
Researchers at UB have successfully developed perfectly aligned carbon nanotubes, bringing researchers closer to developing flat panel displays with excellent viewing angles and high resolution. The technical advances made by the team will help make flat panel displays made with carbon nanotubes affordable, using glass as a substrate.
The 'Dissertation Online' project aims to digitize theses, enabling researchers to search and access them quickly. The initiative involves adding meta-data to scientific texts, developing software tools for targeted searching, and providing guidelines for digital theses.
A recent study published in the journal Science has shed new light on the phenomenon of phantom limbs in amputees. Researchers found that the brain adapts by reorganizing nerve cells and increasing activity in pain-related areas, potentially leading to new strategies for preventing post-amputation pain and recovery of function.
Researchers at University of Wisconsin-Madison have derived and cultured human embryonic stem cells, opening doors to growing tissues from scratch. The achievement has profound implications for transplant medicine and drug discovery, offering new possibilities for treating diseases such as Parkinson's and heart disease.
A University of North Carolina at Chapel Hill study found that domestic violence preceded at least two-thirds of the cases, with black women and young women being disproportionately affected. The research also showed that alcohol regularly contributed to the deaths, and guns were involved in 54% of the homicides.
A team of researchers has determined the complete genetic sequence of Plasmodium falciparum's chromosome, identifying over 200 genes crucial for parasite functions and potential targets for new anti-malaria drugs. The findings may help develop a vaccine and improve treatment options for this deadly disease.
A study of 95 men and women found that pharmacist intervention increased blood pressure control by 55% compared to medical care alone. Pharmacists' counseling on diet, exercise, and medication adherence led to improved outcomes, especially among high-risk minorities.
Researchers at the University of Warwick have created a new process called 'intelligent tooling' that uses an executive pin art toy to create precise industrial moulds. The tool allows companies to produce complex products with high accuracy and reusability.