Researchers at Rice University and the University of Texas-Houston Health Science Center have tracked the path that a polymer-DNA complex takes through a cell to its nucleus, where the new DNA can be read. This study improved our understanding of gene delivery and provided new knowledge for designing better nonviral carriers.
Rockefeller University scientists Dr. Arnold J. Levine and Dr. Robert G. Roeder have been recognized by the General Motors Cancer Research Foundation for their groundbreaking work on cancer research and gene transcription. Their discoveries are paving the way for new diagnostics and therapies, with p53 abnormalities associated with ove...
Scientists found a biochemical link between IgE antibody levels and immune cell receptor count, stanching allergic symptoms. When the drug reduced IgE, new receptors sprouted on immune cells, confirming this link.
Researchers have developed new chemicals that target the butyrylcholinesterase enzyme, which may help attack Alzheimer's disease. The study's findings suggest that inappropriate BChE activity increases the risk and progression of Alzheimer's disease, and preliminary studies indicate improved cognition and learning in rodents.
Northwestern University researchers have identified key peptides that can halt and even reverse kidney disease in lupus. The peptides were found to be effective in delaying the onset of severe kidney disease in young mice and prolonging survival in adult mice with established kidney disease.
Researchers at Max Planck Institute discovered that long-term potentiation in hippocampal neurons is linked to the emergence of new dendritic spines. This phenomenon suggests that structural changes play a crucial role in storing information in the brain.
Research finds patients treated for Hodgkin's disease as children are nine times more likely to develop a second cancer, with specific types of cancer at higher risk. The study suggests regular screening is necessary to monitor patients' lifetime health.
The Howard Hughes Medical Institute is awarding $14 million in grants to support research on infectious and parasitic diseases worldwide. The five-year program will help scientists identify the mechanisms of these diseases and develop new approaches for treatment.