Exisulind, a new selective apoptotic anti-neoplastic drug, delays disease progression in men with recurrent prostate cancer by slowing the rise of PSA levels. The study also found significant inhibition of tumor growth in mice, suggesting potential as a treatment option for advanced prostate cancer.
Scientists have developed a technique to map the circuitry underlying fundamental life processes, shedding light on diseases such as cancer. The study reveals a circular network of regulators regulating regulators controlling the cell cycle, providing new insights into cellular processes and potential therapeutic targets.
Players of the game are more likely to call 911 or see a doctor in case of an actual heart attack. The most interactive version shows the strongest gains, shifting intentions towards quick action and improved understanding of symptoms.
The Rush College of Nursing will integrate information on CAM therapies into undergraduate and graduate nursing curricula and develop continuing education programs for faculty and practicing nurses. The program aims to equip nurses with expertise to assess CAM use, critically appraise therapy safety, and provide patient guidance.
A study of 199 women planning in vitro fertilization found that a 50% pregnancy rate was significantly higher for those who had people praying for them compared to the non-prayer group. The researchers acknowledge the results are incredible and hope to provoke discussion on potential biological or other factors at play.
The NETT trial found that advanced emphysema patients with severe lung obstruction or evenly distributed damage should not undergo Lung Volume Reduction Surgery (LVRS). Instead, high-risk patients had a 30-day mortality rate of 16% and only slightly improved functional outcomes six months after surgery.
Researchers found that forager bees have lower activity levels of a protein called acetylcholinesterase (AChE) in their brains, which may lead to enhanced cognitive performance. A study led by Gene E. Robinson at the University of Illinois showed that reducing AChE activity improved learning abilities in foragers.
Scientists have discovered a process in the brain's cannabinoid system that may lead to new medications preventing relapse to cocaine use. Researchers found blocking this receptor can prevent rats from seeking cocaine after exposure to cues or stress, offering hope for developing new treatments.
Researchers found that caterpillars produce distinct sounds when encountering intruders, which helps them defend their nests and attract predators. In 87% of tests, resident caterpillars successfully repelled intruders using these acoustic signals.
Researchers at Scripps Research Institute develop a therapy to prevent misfolding diseases by incorporating a protein suppressor into the diseased protein, stabilizing it and preventing fibril formation. This approach may also work for other diseases with similar protein-protein interactions.
Researchers found that adding leptin to sibutramine increased weight loss in obese rats, as it prevented a decrease in leptin levels that normally occurs with weight loss. This study provides new clues on how to overcome the plateau effect and may lead to successful treatments for obesity.
Researchers discovered that fathers' cigarette consumption levels impact children's lung function, with higher levels associated with greater deficits. Non-asthmatic girls showed the greatest declines in pulmonary function tests, suggesting a potential link between paternal smoking and childhood respiratory health.
A University of Otago study found that intensive exercise and specific dietary changes can improve insulin sensitivity by up to 20% in otherwise-healthy individuals. The research, which included 79 participants aged 35-60, also showed a significant improvement in insulin action among Māori participants.
A UCSF study found that significant reductions in heart disease risk factors have saved over 430,000 deaths annually, with population-wide dietary changes and widespread use of medications being cost-effective.
A recent study by UT Southwestern Medical Center has identified a significant number of undiagnosed hypertension and diabetes cases in the Dallas County population. The project aims to reduce death and disability from coronary heart disease through analysis of collected data.
A new study by UI atmospheric scientists reveals a 54% chance that climate sensitivity exceeds the IPCC's upper bound, posing significant risks to humanity. The researchers propose an adaptive-decision strategy to mitigate uncertainty and facilitate robust climate-change policy.
Researchers at the University of Illinois and Wisconsin detected a Y-shaped ionized gas filament near the Big Dipper, believed to be produced by radiation from a white dwarf or low-luminosity source. The object's properties differ from other examples, making it difficult to identify its origin.
Researchers at Columbia University Irving Medical Center have discovered a combination of two genes that selectively kill pancreatic cancer cells in test tube experiments. The mda-7 protein and K-ras antisense DNA combination prevents tumor growth in animals, offering a potential new treatment option for this aggressive disease.
Researchers will investigate the cause of substantial increases in Mnemiopsis leidyi population and determine the effects on coastal ecosystems. The study aims to understand the impacts of climate change on zooplankton populations and the local fishing industry.
Scientists successfully inserted a gene into chloroplasts, increasing tryptophan production by 10 times in tobacco plants. This approach could lead to improved yield and value in crops, as well as the production of pharmaceuticals like edible vaccines.
Researchers at the University of Wisconsin-Madison propose that anthocyanins in plants like maples and oaks produce vibrant autumn colors. The pigments shield sensitive photosynthetic tissue from excessive light and other stresses as trees reabsorb nutrients, allowing them to store energy.