Loss of new cell growth gene linked to certain human cancers
The Cables protein inhibits cell growth through a chain reaction effect, prompting decreased division. Its expression may thwart uncontrolled cell growth indicative of cancer.
Science News for September 30, 2001
Genetic changes leading to colon cancer noted in normal tissue
A study by Ohio State University researchers reveals minute genetic changes in normal colonic tissue that may signal later development of certain types of colon cancer. The changes, which occur through hypermethylation, appear to be age-related and associated with microsatellite instability.
IIT develops technology that may help doctors identify blood pathogens faster
Students at IIT's Interprofessional Program developed a blood sniffing e-nose that can identify hundreds of specific scent signatures, potentially cutting testing time down to minutes. The technology uses electronic noses sensitive to microscopic particles, similar to the receptors in the human nose.
NIDCR funds centers for research to reduce oral health disparities
The new centers will focus on reducing early childhood caries and addressing disparities in oral cancer screening among minority groups. Researchers will investigate the effects of tooth decay on quality of life, explore ways to involve pediatricians in prevention, and examine oral microbes that trigger tooth decay.
Making new veins
Researchers at UCSF have discovered that continuous expression of the HIF-1a gene can induce formation of new blood vessels in mice. This breakthrough has significant therapeutic potential for treating diseases such as diabetes and recalcitrant wounds.