Researchers have isolated a key component of cell death signals that can be targeted to prevent cancer growth. By understanding how these signals interact, scientists hope to develop new anti-cancer therapies.
Dogs on a reduced-calorie diet lived up to 13 years, while those with high-calorie diets averaged 11.2 years. The study also found that lean body conformation and dietary restriction can help prevent chronic illnesses like osteoarthritis.
Researchers conducted a Phase I clinical trial of endostatin, showing that it decreases blood flow to tumors and promotes the death of cancer cells. The study also found minor anti-tumor activity in two patients, but no long-term responses were seen.
A new generation antipsychotic quetiapine, combined with mood stabilizers, shows improved efficacy in treating manic symptoms of bipolar disorder. The study results indicate that more patients experience full resolution of manic symptoms when treated with quetiapine.
Researchers at Argonne National Laboratory are developing an ice slurry procedure to cool the blood and brain cells after cardiac arrests, with the goal of improving survival rates. The ice slurry cools the brain by 2-5 degrees Celsius quickly, giving medics more time to revive normal blood flow and brain activity.
A global consensus on histopathological diagnostic criteria for Parkinson's disease is within reach thanks to an interactive website. NMDA receptor antagonists failed to show efficacy in clinical trials of stroke and traumatic brain injury, but lessons learned will guide new developments.
Researchers at UNC Chapel Hill used nuclear magnetic resonance spectroscopy to study the effects of crowded environments on protein shape. They found that intrinsically unstructured proteins exhibit a definite folded-up shape when inside cells, unlike their apparent lack of structure in water solutions.
Cosmologists suggest universe may collapse in 10-20 billion years due to dark energy, reversing the popular view of a runaway universe. The Stanford team's model predicts the universe will slow down and contract, leading to a cosmic 'big crunch',