Research analyzed DNA differences among 50 squirrel genera to deduce their interrelationships and evolutionary history. The study found that climate change and geological events played a significant role in shaping the squirrel family tree, with major branches diverging around 5 million years ago.
Researchers found that individuals with two copies of the met form of the COMT gene had a more pronounced response to pain, while those with two copies of the val form reported less pain and fewer negative emotions. The study used PET brain imaging and controlled jaw pain to investigate the role of genetic variation in pain tolerance.
Researchers use bio-ferrography to capture tiny particles in synovial fluid, enabling the creation of a diagnostic atlas for orthopedic surgeons. The atlas will help identify potential problems with implants prior to revision surgery.
A meta-analysis of 31 trials involving over 4400 patients found that continuous antidepressant treatment for one to two years significantly reduced depressive relapse rates compared to placebo. The study suggests that many patients remain at risk of recurrence after initial treatment and may benefit from extended medication
A Virginia Tech study found that women are increasingly finding their homes to be a haven of satisfaction, rather than their workplaces. This challenges the long-held assumption that women seek work as an escape from family obligations.
A study published in The Lancet found that treatment for one to two years with antidepressants substantially reduced the likelihood of relapse compared to discontinuing active treatment. The average rate of relapse on placebo was nearly double that of treatment, highlighting the benefits of long-term medication adherence.
Researchers found that both nortriptyline and bupropion, when combined with counseling, helped smokers attain periods of abstinence but had limited effectiveness in quitting for a year. The study showed that antidepressant therapy and counseling can aid in achieving short-term abstinence for cigarette smokers.
The Singleton case has raised concerns about forced medical treatment of the mentally ill and its impact on the death penalty. The US Supreme Court must rule against this practice to restore competence for execution as a medically and ethically untenable dilemma.
Researchers found that specific genetic variants, such as the val158met polymorphism in the COMT gene, influence an individual's sensitivity to pain. This genetic variation affects brain regions involved in pain perception and emotional regulation, leading to increased pain ratings and a more negative internal state.
A recent study by Imperial College London found that genetically modified mosquitoes (GM) lose their test marker gene rapidly when interbred with unmodified mosquitoes, posing challenges for malaria control. The researchers suggest using crossing regimes to minimize deleterious mutations and improve the competitiveness of GM mosquitoes.
A new treatment option for heroin addiction has shown a promising 75% success rate in reducing opiate use, according to a recent study. The combination of buprenorphine and intensive psychosocial therapy was found to be effective in preventing relapse and reducing criminal activity among patients.
Researchers at Rockefeller University reveal a crucial link between the Ezh2 protein and chromatin modifications, enabling the development of a wide range of antibodies. The discovery provides new insights into B cell biology and the immune system.
Two studies found that bidis and reduced-exposure products marketed as less toxic do not effectively reduce smokers' exposure to lethal constituents of cigarette smoke. Instead, they may promote heavier smoking and introduce new risks.
Researchers at Zengen developed a 'super peptide' that kills Candida albicans with high candidacidal activity, outperforming existing antimicrobial peptides. The discovery may help understand the unique mechanism of action of a-MSH peptides and unlock new treatments for fungal infections.
The Lancet reports a severe decline in Iraq's healthcare infrastructure, exacerbated by the Gulf War and 12 years of economic sanctions. The US military's preparation for chemical and biological warfare has also contributed to the humanitarian disaster.
Researchers found that selegiline hydrochloride significantly increased smoking cessation rates among participants, with 45% quitting after 8 weeks of treatment. This suggests the MAO-B inhibitor may be an effective treatment for nicotine addiction.
Despite years of decline, trade unions are finding new ways to gain support and influence, such as community links and international agreements. Research shows that partnerships with employers and local consultation can drive growth, but challenges remain in certain workplace environments.
Researchers have found that addictive drugs, such as cocaine, morphine, and amphetamines, increase the sensitivity of dopamine-producing neurons in the brain. Stress triggers a similar response, which may lead to addiction. The study's findings could help develop new treatments for addiction.
Researchers have discovered that Bt toxins can kill a range of parasitic nematode species, including those affecting humans, animals, and crops. The findings suggest the potential for developing an inexpensive and environmentally safe means of controlling parasitic roundworms.
A study published in Archives of Neurology found that Parkinson's patients treated with levodopa have higher levels of homocysteine, a risk factor for heart disease and dementia. The study suggests that monitoring homocysteine levels may be necessary for patients at risk of heart disease.
Researchers at Zengen discovered that synthetic alpha-Melanocyte-Stimulating Hormone (a-MSH) has an anti-inflammatory effect in celiac mucosa, which may control the inflammatory response and limit epithelial damage. This finding could lead to a medical treatment for Celiac disease, currently managed only with a strict gluten-free diet.
Researchers have discovered a new six-drug chemotherapy regimen that significantly improves the overall survival rate of Ewing's sarcoma patients to 72% without metastases. The treatment has become routine care for patients with localized disease and has marked a substantial improvement in survival rates.
Researchers at the University of Illinois Chicago have developed a new method for growing conducting polymers, called Surface Polymerization by Ion-Assisted Deposition. This method allows for the creation of large areas of films with controlled chemistry and shape on a nanometer scale.
Researchers found the prevalence of overweight among Los Angeles County school children to be 20.6 percent, with higher rates among boys and Latinos. An email-based program for nutrition intervention was also shown to be effective in changing dietary behavior, with over 50% of participants reporting success.
Researchers found a correlation between fluence and duration for both short and long bursts, but the degree of this relationship is statistically different at a 4.5 sigma significance level. This suggests that short bursts may originate from fundamentally different physical processes than long bursts.
A Bayer BP team introduced six decision points to help determine whether to continue developing a new drug for dissolving blood clots. The process has improved forecasting technical and market risks, allowing for more informed decisions.
A major study found that patients who survive acute respiratory distress syndrome (ARDS) show significant improvement in exercise capacity and quality of life over time. Despite persistent muscle wasting and weakness, survivors achieve 66% of healthy patient exercise capacity at one year and return to work in most cases.
A recent study analyzed data from the Veterans Affairs HIV patient population between 1993 and 2001 and found a sharp decline in overall death rates among patients. Despite concerns about vascular disease as a side effect of HAART, the study suggests that these drugs may not increase the risk of this condition.
Researchers created a 3D map of protein structures, grouping them into four distinct classes based on their folds. The map reveals the evolutionary history of proteins and holds promise for understanding cellular functions and designing more effective pharmaceutical drugs.
Researchers discovered that normal nerve cells can use IRES to produce large quantities of protein, mimicking viral behavior. This switch allows for massive production of specific proteins like ELH hormone, potentially impacting learning and memory processes in the brain.
Research suggests self-control can be depleted, leading to increased difficulty with problem-solving and impulse control. Replenishing self-control through rest and positive emotional experiences may help overcome behavioral health problems like addiction.
The KESS research team will use cutting-edge technology to study the dynamical and thermodynamical processes controlling the Kuroshio Extension and its recirculation gyre. The study's findings will have significant implications for fisheries, climate research, and understanding storm tracks.
A recent study found that medical consent forms are typically written at a 10th-grade reading level, despite an estimated one in two American adults struggling with eighth-grade level literacy. To improve readability, researchers suggest using simpler language and alternative methods like multimedia presentations.
The session addresses heart disease in postmenopausal women, including sub-clinical atherosclerosis predictors and prevention measures. It also explores sarcopenia and frailty in older women, discussing muscle mass loss and body composition changes that contribute to disability.
A recent study reveals significant discrepancies in shark fin trade reports, with estimates suggesting under-reporting of 24-49% compared to Hong Kong's quantities. The study highlights the need for continued monitoring and analysis in key seafood trading centers like Hong Kong.
A new study by King's College, London, found that children living with their biological fathers who have low levels of antisocial behavior may experience more behavioral problems. In contrast, highly antisocial fathers can contribute to the development of conduct problems when they live with their children.
A study found that recent radiologists interpreted screening mammograms more accurately than those with less training, while facilities with higher diagnostic volume showed improved accuracy. The researchers suggest additional studies to clarify the complex relationship between radiologist experience and mammogram interpretation.
Researchers found that family members who are not genetically at risk may feel left out of discussions about disease prevention. Mothers play a crucial role in facilitating information sharing within families, according to the study.
Researchers at Cyclis Pharmaceuticals have discovered a new mechanism for treating cancer, involving the activation of the E2F1 protein with small molecule drugs. The findings, published in the Proceedings of the National Academy of Sciences, show that this approach can selectively kill cancer cells while sparing normal cells.
Researchers found that patients with xeroderma pigmentosum had lower DNA repair capacity than control subjects, increasing their risk for melanoma. A natural compound called deguelin may have potential as both a chemopreventive agent and a therapeutic agent against lung cancer.
A study published in the American Association for the Advancement of Science suggests that estrogen levels influence women's ability to suppress pain. The researchers used PET scans to examine the brain's response to pain in individuals with different gender, hormone, and genetic profiles.
Researchers used titanium mesh and bone marrow cells to promote new bone growth in rats, achieving better results with fibronectin-coated mesh and a flow perfusion system. The study presents an alternative method for treating bone defects and highlights the potential for improving cell growth and bone mineralization.
A study by Professor Shelley Peterson found that teenagers' writing is closely linked to gender stereotypes, with students tending to write socially acceptable themes. The research revealed that students were reluctant to explore non-traditional topics, instead favoring traditional gender roles and styles.
A new laser-based technique can detect developing cavities in teeth, revealing defects at very early stages of development. This photo-thermal method avoids the need for heavy lead aprons to protect patients from hazardous X-rays, making it a promising tool for preventive treatment.
Bradford Parkinson, a pioneer of GPS technology, has been awarded the 2003 Charles Stark Draper Prize for his significant contributions to the development of the original GPS system architecture. He is also recognized for his work on improving GPS accuracy and its applications in various fields.
Researchers have made a significant breakthrough in developing a cancer vaccine by attaching tumor material to antibodies, inducing an immune response against cancer in animal experiments. The vaccine's effectiveness may also be applied to other diseases such as arthritis and whooping cough.
A University of Melbourne-led team has reached a broad agreement on the ages of Lake Mungo remains, painting a new picture of human and climatic history in Australia. The research boosts the age of Mungo Lady's cremation by 10,000 years, placing both at 40,000 years old.
Scientists have created a 3D map of the protein universe, organizing over 500 common motifs and revealing clusters that resemble cigars. This map helps visualize the relationships among all proteins in nature, shedding light on evolutionary changes and potential applications in biomedical research.
Biologist Patrick Jansen found that acouchy rodents, large guinea-pig-like animals, disperse larger nuts further away from trees. This leads to more successful germination and increase in nut-producing trees over time. Protecting animals in managed forests is crucial for tree regeneration.
Astronomers have strengthened the case for a massive black hole at the galactic center with observations of a newly discovered star. The star's high velocity and proximity to the black hole confirm its presence, ruling out alternative explanations.
Tamoxifen treatment reduced the risk of benign breast disease and biopsies in high-risk women. Women treated with tamoxifen had a 28% lower incidence of benign diseases than those on placebo.
A recent study found that combining behavioral therapy with medication is more effective in treating obsessive-compulsive disorder (OCD) than using medication alone. The treatment combination resulted in significant improvements in social functioning and quality of life, even when initiated after 3-9 months of medication treatment.
A new theory proposes Chaco Canyon's powerful political system kept other Pueblo peoples under its thumb from 1000 to 1125. The city's elite ruled a region containing tens of thousands of people, with influence stretching hundreds of miles.
Prehispanic farmers in the southwest US employed ingenious strategies to overcome challenges like limited moisture and short growing seasons, including moving run-off water and using gravel mulch. They were able to extend frost-free periods and grow crops like cotton in marginal areas.
Gerald R. Smith pinpointed three North American regions at greatest risk for freshwater fish diversity: southern Appalachian, Klamath River Basin, and Caribbean coastal drainages of eastern Mexico. Habitat destruction due to water diversion, agriculture, and mining threatens these areas' unique species.
The Economic & Social Research Council (ESRC) has introduced a new professorial fellowship scheme to enable top scholars to pursue innovative research. The fellowships will run for three years, providing funding for PhD students, research assistants, and travel expenses.
Comparative literature expert Eric Cazdyn examines the relationship between Japanese film history and societal shifts. His research reveals how changes in film techniques reflect broader cultural transformations, including increased citizen participation and experimentation during times of economic turmoil.
Researchers at OHSU produced mice lacking the WAVE-1 protein, showing balance, motor, learning and memory deficits. The study suggests that mental retardation involves many more areas of the brain than initially thought.
Climate experts Tom Wigley and Charles Knight will discuss the future of the Earth's atmosphere and the impact of greenhouse gases on climate change. They will also explore the science behind artificial snow formation, including nucleation and ice nuclei.
A study published in the Journal of Medical Systems found that internet use empowers patients and improves the physician-patient relationship. Patients who access health information online can arrive with background knowledge and ask informed questions, saving time for doctors.