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Science News for July 12, 2003


One drug, two targets

Researchers have developed a new generation of targeted cancer therapies using bispecific antibodies that target multiple proteins in cancer cells, increasing radiation sensitivity and specificity. The therapy is expected to improve treatment outcomes for patients with breast and ovarian cancers.

SourceFox Chase Cancer Center·DateJul 12, 2003
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Older drug could have exciting new role in treating colorectal cancer

Researchers at Wake Forest University Baptist Medical Center have found that oxaliplatin can effectively treat human cancers resistant to other platinum-based therapies. The drug works differently than cisplatin and shows promise in combination with radiation therapy for patients with earlier stages of rectal cancer.

SourceAtrium Health Wake Forest Baptist·DateJul 12, 2003

New generation of treatments shows promise for cancer patients

Researchers have discovered a new bone-targeted mTOR inhibitor that decreases both tumor proliferation and bone breakdown for the treatment of bone cancer. Additionally, studies have shown efficacy of radioimmunotherapy using radiolabeled HerceptinTM in combination with gemcitabine in treating intraperitoneal disease.

SourceAmerican Association for Cancer Research·DateJul 12, 2003

Telomere shortening may be early marker of cancer activity

A new study suggests that telomere dysfunction may play a causal role in human intraepithelial neoplasia (IEN) found in precancers. Short telomeres were found in the majority of precursor lesions across various types of cancers, indicating potential early molecular mechanisms underlying cancer development.

SourceAmerican Association for Cancer Research·DateJul 12, 2003