Researchers at SLU have developed oncolytic adenoviruses that target specific types of cancer cells, such as colon and lung cancer. These engineered viruses attack and destroy cancerous cells through a mechanism different from chemotherapy or radiation.
A recent study found that even health-conscious women are more likely to have had a mammogram or Pap smear than undergone a colonoscopy. Doctors suggest using breast cancer screening appointments as an opportunity to educate women about colorectal cancer risk and increase awareness.
Researchers have made breakthroughs in understanding the molecular mechanisms driving pancreatic cancer's rapid growth and resistance to treatment. They've identified new targets for therapy, including a protein sponge that suppresses tumor growth and a novel mechanism for chemoresistance.
A study published in Cancer Research identified a cancer-causing gene, HMG-I, that contributes to the development of leukemia and lymphoma in humans. The researchers found that overexpression of the gene led to the rapid development of tumors in genetically engineered mice.
A unique computer system developed at the University of Michigan Health System reduces risks while improving patient care quality and continuity. The Discharge Navigator system automates information transfer, streamlines handoffs, and enhances patient education and satisfaction.
Researchers found an inverse correlation between Rb2 expression and VEGF in liver tumors. The study suggests that lower Rb2 expression and higher VEGF levels can predict the aggressiveness of liver cancer, regardless of tumor stage.
Researchers at the NIH will conduct a clinical study to assess the safety and efficacy of hematopoietic stem cell transplantation in treating severe forms of lupus. The study aims to create a new immune system that doesn't attack healthy cells, offering hope for patients with limited treatment options.
A new lab-on-a-chip technology can detect milk contamination and identify the botulinum toxin in as little as an hour with test results available in minutes. This innovation could lead to faster treatment for potential botulism toxin exposure, reducing its high specific toxicity as a bioterrorism threat.
A recent Emory University study found that adults with better mental health have a lower risk of cardiovascular disease. Only 17% of the sample met full mental health criteria, highlighting the need for healthcare professionals to consider mental well-being in treating patients with heart conditions.
A seven-month study found that parenting skills training improved attitudes towards alcohol and sex among rural black children. However, the training did not address the role of fathers, who were rarely involved in the sessions.
A study of 819 early adolescents found that unsupervised out-of-home care and lack of parental monitoring predict increased problem behaviors. In contrast, consistent adult supervision and community engagement appear protective against these issues.
Researchers found that soft flaky skin helps reduce drag caused by friction and shedding of the skin disturbs whirlpools of water called vortices, reducing drag. The study could help build faster boats and submarines using natural dolphin-inspired solutions.
Research identifies genetic and environmental protective factors contributing to childhood resilience. Genetic factors influence behavioral and cognitive resilience to poverty, while maternal involvement in stimulating activities helps promote intellectual development. Both genetic and social-environmental sources of protection are inv...
A study found a higher prevalence of the D variant in the ACE gene among Gulf War veterans with chronic fatigue syndrome. Veterans with specific genetic variants were more likely to develop CFS/ICF, suggesting an interaction between genetics and environmental factors related to deployment.
A study found that parents' close relationships with their children and efforts to monitor their behavior can help prevent adolescents from engaging in substance use and delinquent activities. Parental control was also a strong predictor of lower levels of problem behavior, regardless of the level of knowledge gained through monitoring.
Researchers found large ozone trends in low latitudes and the Southern Hemisphere, indicating the ozone smog problem has expanded globally. The study suggests that increasing energy use worldwide causes large-scale ozone increases, reducing global air quality.
Research suggests that when mothers use a controlling approach, children become disengaged and perform poorly in school. In contrast, an autonomy-supportive approach improves children's performance immediately and leads to better grades over time. The study emphasizes the importance of this parenting style for low-achieving children.
A new molecule, AM1172, has been identified as a potential treatment for overeating and drug dependency. By regulating the brain's natural 'bliss' system, AM1172 may help counterbalance feelings of anxiety and depression that contribute to obesity and substance dependence.
The program, which translates research into prevention programming, focused on mothers and their 11-year-old children. Participants showed improved skills in parenting behaviors, such as discipline and communication, leading to better outcomes for the young people.
A study found that moderate alcohol consumption increases plasma DHEAS levels in both men and women, decreases testosterone in men, and has no effect on estradiol levels. These findings suggest that DHEAS may play a protective role against atherosclerosis.
Researchers using GPS satellites have discovered a pattern of land movement across North America, with Canadian sites rising and US sites south of the Great Lakes sinking. This post-glacial rebound affects not only industries but also international water management.
A 125-mile-wide crater off Australia's coast has been linked to the Great Dying, a period when 90% of marine life and 80% of land life became extinct. Researchers found evidence of shock quartz and melt layers in ancient cores drilled by oil companies, matching the timeline of the end-Permian era.
Researchers confirm Bedout impact crater as potential 'smoking gun' of a massive meteor collision, linked to the Permian-Triassic extinction and the Cretaceous-Tertiary boundary mass extinctions. The team found evidence of shock-melted rock formations, feldspar glass, and similar correlative lava flows in India and Siberia.
Researchers found that birds' photoreceptors can detect the Earth's magnetic field by sensing changes in light energy. This process involves specialized visual systems that allow animals to navigate using the magnetic compass. The discovery sheds new light on the mechanisms behind animal magnetism and its potential applications.
Common in 18- to 30-month-old children, scale errors occur when youngsters try to perform actions on miniature objects despite knowing they're too small. The study suggests a failure of inhibitory control and immaturity of the prefrontal cortex.
A review of general population longitudinal studies found consistent associations between cannabis use and lower educational attainment and increased use of other illicit drugs. However, the evidence was less clear on psychological health problems and problematic behavior. The authors emphasize the need for more research to better unde...
A study of 10,440 single-born infants found no increased risk of hospitalization for asthma among children born to mothers who consumed alcohol during pregnancy. Despite this, researchers caution that high prenatal alcohol exposure may still have unknown health effects.
Researchers find that alkylating agents can induce necrotic cell death in cancer cells by damaging DNA and activating the PARP protein. This process is specific to proliferating cancer cells and does not affect healthy cells, offering a potential new approach to treating cancer.
Catalina Achim, a Carnegie Mellon University chemist, has received the prestigious NSF CAREER award to support her research on incorporating metal ions into peptide nucleic acid (PNA). The grant will also enable her to develop an interdisciplinary course bridging inorganic chemistry and art.
The Department of Defense Smallpox Vaccination Program reported over 50 cases of myopericarditis, a heart muscle inflammation, following vaccination. Most soldiers experiencing complications have recovered well with therapy, but researchers stress the need for further study to better understand potential cardiac risks.
A study led by Professor Mary Naylor demonstrates a model of care that has important implications for the nation's healthcare system. Advanced practice nurses coordinated care provided by various healthcare team members to reduce hospital readmissions and improve patient outcomes.
A facultative symbiont is identified in pea aphids associated with host plant specialization, increasing fecundity on clover and failure to survive on alfalfa. Genetic data suggests the aphid genome, not symbiont, causes specialization.
Researchers are exploring innovative treatments for atrial fibrillation, including radio frequency ablation and gene transfer techniques. These methods aim to regulate the heart's irregular rhythm without the dangerous side effects of current medications.
The Cardiff Institute of Society, Health and Ethics aims to produce high-quality evidence to address health inequalities and improve public health in Wales. The institute will focus on tackling issues such as smoking, alcohol consumption, and urinary disorders through community-based initiatives and research.
A study found that nearly 8 out of 10 establishments sold alcohol to visibly intoxicated patrons, with younger servers more likely to serve. The study suggests increasing enforcement, comprehensive training, and permitting dram-shop liability lawsuits could reduce such incidents.
The new centre aims to help firms adopt sustainable practices through research on advanced technologies, miniaturisation, and waste minimisation. It will also explore shared and collaborative logistics, warehousing, and transport systems to achieve sustainable economics for the manufacturing industry.
A study found that rectal artesunate significantly reduced parasite concentrations by over one-third in both children and adults. Early administration of this treatment may help reduce malaria-related morbidity and mortality, particularly in rural communities with limited healthcare access.
Researchers at Boston College are studying the molecular mechanisms of B-1a cells, which can lead to autoimmune diseases and leukemias like chronic lymphocytic leukemia. The new NIH-funded program project aims to understand how these cells proliferate and enter the cell cycle.
Researchers have identified a flagellar and basal body proteome that includes the BBS5 human disease gene by comparing the genetic codes of humans and the green alga Chlamydomonas. This discovery sheds light on the complex structure and function of cilia, which are essential for various cellular processes.
Researchers discover novel gene BBS5, necessary for generating cilia and flagella, which are involved in the development of Bardet-Biedl syndrome. The study confirms that BBS is caused by defects in cilia, a theory first proposed by Dr Philip Beales.
Researchers found that estrogen therapy can suppress adrenal androgen production, with marked reductions in DHEA-S, A4, and testosterone levels. The study suggests a potential mechanism for how estrogen affects androgen hormones, and has implications for postmenopausal women.
Researchers have made significant breakthroughs in regenerating damaged heart muscle, improving heart function and survival rates with human embryonic stem cells. The study suggests a promising method for treating congestive heart failure, offering hope for millions of patients worldwide.
The National Visual Analytics Center aims to improve terrorist threat detection and analysis of vast information streams using visual analytics techniques, protecting individual privacy in the process. The center will develop tools for evaluating new technologies and support information sharing in a secure environment.
Researchers have discovered that nonalcoholic beer can impart cardiovascular benefits without the negative effects of alcohol. The study found that nonalcoholic beer reduced platelet activation and blood coagulation just as well as alcoholic beverages, which may help prevent conditions such as coronary heart disease and atherosclerosis.
A study found that treating cirrhotic patients with synbiotics or fermentable fiber can alter the gut flora, lowering ammonia levels and improving clinical signs of brain and liver dysfunction. The treatments were effective in reversing minimal hepatic encephalopathy in 50% of patients, compared to 13% in the placebo group.
A recent study found that boys are at least twice as likely to have dyslexia and reading difficulties as girls. The research suggests that early identification and intervention are crucial for providing effective treatment, and highlights the need for educational programmes to address boys' emerging disabilities.
A Kansas State University computer science professor aims to develop autonomous cooperative robotic teams that can work together without human intervention. He hopes to create robots that can adapt and reorganize to accomplish their mission, enabling more efficient and cost-effective operations in various industries.
Justin Crowley receives a $240,000 award to study neural circuit formation in the primary visual cortex. His research aims to understand how neurons form functional connections during development, which could lead to treatment options for nervous system damage caused by traumatic injury or disease.
The value of screening varies by condition, and it can both identify treatable conditions and subject patients to invasive evaluations. Researchers recommend carefully considering each condition's worthiness and exploring prospective studies on screening efficacy.
Researchers have identified six essential genes for cilia formation in humans, which could help diagnose and treat diseases such as infertility, pulmonary diseases, and vision problems. The discovery provides a critical new tool for medical researchers to understand the genetic basis of these disorders.
A recent study on a rocky intertidal shore in Washington State discovered an alternative state where mussels replace algal dominated assemblages. The starfish play a key role in controlling mussel distribution and abundance, leading to two possible outcomes: gradual recovery or persistent transformation.
Researchers identified nicotinamide riboside, a natural compound in milk, as a potential treatment for metabolic disorders and improved cancer therapy. The discovery may offer an alternative to existing treatments, such as niacin, which has uncomfortable side effects.
A recent study published in Ecology Letters found that increased atmospheric carbon dioxide can lead to a significant increase in algal productivity, with up to 40% to 50% more growth in nutrient-rich environments. This could result in more severe nuisance blooms, particularly in freshwater and saltwater systems.
A prospective study found that breastfed preterm infants had lower ratios of LDL to HDL cholesterol and CRP concentrations compared to formula-fed counterparts. Longer human milk intake was associated with additional benefits on cardiovascular health.
Researchers found that partial defoliation stimulates micro-organisms to release more nitrogen in the soil. This increase in nitrogen availability allows certain trees to grow larger leaves and recover from initial damage.
Researchers identified a plant-like enzyme, CDPK4, essential for malaria parasite transmission to mosquitoes. The findings provide a promising new target for developing safe and effective anti-malarial drugs.
Science.gov 2.0 enhances the interagency science portal, searching 47 million pages of government R&D results in relevancy-ranked order. The new metasearch technology brings together the 30 largest databases, making them searchable via a single query.
Cardiovascular disease is a leading cause of death in US women over 45, with inadequate screening contributing to high mortality rates. Women often fail to receive aggressive risk factor management, exacerbating poor outcomes compared to men.
A recent study found that statins reduced brain lesions in people with MS by 44% after six months of treatment. Researchers suggest that statins may be beneficial for patients as monotherapy or as an add-on to existing therapies, but more data is needed to confirm their efficacy.
A recent survey conducted by Harris Interactive found that Americans hold engineers in high regard, with 77% of respondents believing they contribute to strong economic growth and national security. The survey also revealed that engineers are widely respected for their ability to make a positive contribution to society.