Bone marrow derived stem cells can give rise to heart muscle cells through transdifferentiation, a process that has sparked debate and potential applications in heart repair and transplantation. The concept challenges traditional dogma of tissue specific stem cell differentiation in adults.
A new study found that eccentric muscle training, such as hiking downhill, improves glucose tolerance by 25.0%, compared to 9.4% with concentric training, like hiking uphill. This research provides insight into the specific metabolic effects of different types of exercise on glucose metabolism in humans.
The Euro Heart Survey on diabetes and the heart found abnormal glucose regulation is common in patients with coronary artery disease. Patients with diabetes face a dismal prognosis, but those without known diabetes can benefit from improved treatment standards.
A new analysis of the CHARM* study program shows that Atacand reduces all-cause mortality by 12% and cardiovascular mortality by 16%. The medication is recommended for all patients with heart failure and low LVEF, regardless of background treatment.
Researchers used NASA's MODIS instruments to study dark water patches off the Florida coast, detecting glowing phytoplankton blooms. The findings suggest a connection between rivers and the ocean ecosystem, highlighting the need for coordinated efforts to mitigate black water events.
The IEA GHG Weyburn project, a $40 million research initiative, involved 24 organizations in Canada, Europe, and the US, producing over 470 deliverables. The project's findings demonstrate the feasibility of large-scale CO2 capture and storage.
The article reports a record number of active medical residents (99,964) in the 2003-2004 academic year, with a notable increase in female graduates. Several specialties experienced a decline in male graduates, while others saw an increase in female graduates, reflecting a trend towards a more specialized and diverse medical workforce.
The Center for Quantitative Biology aims to tackle complex biological questions using advanced computing, microscopy, and gene chips. It will train future research leaders through a new undergraduate and graduate curriculum.
Women with diabetes having acute coronary syndrome are at a higher risk of presenting with ST-elevation-ACS and dying in hospital, compared to men. Diabetes has a differential effect on the pathophysiology of ACS based on patient sex.
A recent study found that cancer survivors experience significant long-term burdens, including lower quality of life and lost productivity, persisting even beyond 10 years after diagnosis. The burden varies by cancer type, with those diagnosed with shorter-survival cancers reporting greater impacts.
A study by Daphne Bavelier and her team found that visual information is less effective at holding seven items in short term memory compared to auditory information. However, a new test design revealed that both sight and sound are equally important for cognitive ability.
Researchers have identified a crucial function for microcephalin, a protein involved in primary microcephaly, a rare neurological disorder. The discovery links microcephalin's function to DNA damage responses that prevent cancer development, suggesting potential therapeutic applications.
Researchers found that embryonic endothelial progenitor cells could reduce infarct size and improve regional myocardial function when delivered regionally, but not systemically. This study uses a large animal model to test the cardioprotective potential of these cells, paving the way for future human trials.
Researchers analyzed data from over 400,000 breast cancer patients to calculate probabilities of death from breast cancer vs. all other causes combined. They found that patients with ER-negative tumors and larger tumors were more likely to die from their cancer than those with ER-positive tumors and smaller tumors.
Studies found strong evidence supporting treatment of systolic hypertension in older persons with SBP of at least 160 mm Hg. Treatment guidelines recommend thiazide diuretics and long-acting calcium channel blockers as first-line therapy for SH. Despite effectiveness, poor control of SH among patients is increasing.
A study led by Mayo Clinic cardiologist Veronique Roger found that cardiac rehabilitation can improve survival rates for heart attack patients by almost 50%. However, women and elderly patients were less likely to participate in exercise programs due to factors such as lack of transportation and support networks.
Bechtel is collaborating with INEEL to test and develop critical infrastructure, including process control and SCADA systems. The partnership aims to provide scalable and secure testing capabilities for government and industry.
The new guidelines cover prevention and early diagnosis of chronic conditions, such as diabetes and heart disease, and provide evidence-based primary care interventions for people living with HIV. The guidelines also focus on caring for women and children with HIV, making them a valuable resource for a wide range of healthcare providers.
Researchers used an extremely sensitive measurement technique to study myosin VI's movement. They found that it walks in a 'hand-over-hand' mechanism, causing part of the protein to come undone. This challenges the long-held inchworm motion theory for this molecular motor.
A study found nearly 12% of salmonellosis cases in children under 5 were reptile-associated. Experts recommend keeping reptiles out of households with young children to prevent infection.
The green tea gum helps eliminate free radicals that can damage DNA and lead to cancer. It also protects healthy cells by targeting cancer cells for destruction.
Nebel was recognized for his outstanding contributions to the dairy industry through his research on electronic heat detection, leading to the development of the Heatwatch system. He is a renowned expert in reproductive efficiency and Extension specialist with over 400 published articles.
Researchers at the University of Illinois have found that sulforaphane, a compound in broccoli and other cruciferous vegetables, can block the growth of late-stage breast cancer cells by disrupting microtubules. This discovery could lead to new strategies for preventing and treating breast cancer.
The NHGRI has launched four centers to pioneer interdisciplinary research on the ethical, legal and social implications of genomic knowledge. The centers will assemble teams of experts to develop innovative approaches to addressing pressing issues in genome research.
A recent survey found that young people are more likely to smoke and have poor eating habits, with rates of obesity increasing across all ethnic groups. Despite some improvements in older adults, these unhealthy behaviors are expected to have serious consequences for future generations.
Researchers found that summer temperature is the most important variable in predicting fire extent, with increases expected in Montana, Wyoming, and New Mexico. Global warming could lead to more frequent and extensive fires, reducing old forests and habitat corridors for threatened species.
Researchers analyzed data from over 400,000 breast cancer patients to estimate the probability of death after diagnosis. The study found that breast cancer patients with ER-negative tumors were more likely to die from their cancer than those with ER-positive tumors.
The study found that approximately 1 in 5 subjects had previously undiagnosed diabetes, while over 1 in 4 had impaired glucose tolerance. Lifestyle changes and medication may help prevent the progression of impaired glucose tolerance to full-blown diabetes and its associated complications.
A survey of 10th-grade students reveals that many teens have made conscious efforts to lose weight, with girls more likely to diet than boys. The study also explores the impact of calcium-rich diets on girls' weight, finding no significant increase in body weight or BMI.
The number of full-time medical school faculty members increased by 4.6% from 2002-2003 to 114,549 in 2003-2004. The number of U.S. medical school applicants rose by 3.5% to 34,786 for the 2003 entering class, with women making up a majority of applicants and graduates.
A study published in JAMA Network found that women with breast cancer detected by mammography screening have better estimated 10-year distant disease-free survival rates compared to those without screening. The researchers also discovered that tumors detected through screening had a lower risk of distant recurrence, suggesting that mam...
Researchers have identified novel compounds that show promise in treating neuroblastoma and glucose-deprived tumors, while also developing new assays to measure the effectiveness of immunotherapy. Additionally, scientists outline best methods for determining the health benefits of diet and exercise.
Scientists developed a new near-field microscope that excites local lattice vibrations in polar crystals, allowing for nanoscale mapping of crystal quality. The technique reaches a 100-fold higher resolution compared to conventional infrared microscopes and enables non-destructive chemical analysis, nanoscopic sensors, and optical data...
Loewen, an INEEL scientist, has been selected for a congressional fellowship to share his knowledge of nuclear science and technology with a member of Congress. The fellowship aims to bring a knowledgeable view of nuclear matters to Congress and provide a resource for Congress in science and engineering.
Research finds full-body CT scanning increases cancer mortality risk associated with radiation exposure, posing a significant threat to asymptomatic adults. The effective dose of radiation from a single scan is comparable to atomic-bomb survivors' doses, leading to an estimated lifetime risk of cancer in one in 50 people.
Following guidelines improved acute reperfusion and adjunctive treatment of STEMI in diabetics, leading to a 36% relative reduction in hospital mortality. Diabetes mellitus significantly increases the risk of developing coronary artery disease.
A study of 4,223 individuals found that subclavian artery stenosis is a significant risk factor for hypertension. Patients with peripheral arterial disease are five times more likely to have SS.
A recent report by NIST and RTI International estimates software difficulties in the construction industry have significant financial implications. The analysis breaks down data exchange-related losses across design, construction, and operations stages, identifying barriers to improvement.
Professor Ken Donaldson proposes the creation of a new discipline, nanotoxicology, to study the potential harmful effects of nanoparticles. The importance of nanotechnology is debated, but its adverse impacts need to be studied to ensure sustainable development.
The study uses nearly 1000 SNPs to define the genetic and evolutionary types of several anthrax isolates, providing a critical step toward future detection of this potential public threat. The results also establish a model for other biothreat pathogens and common public health-related diseases.
A study published in Diabetes shows that six months treatment with Laszarin TM reduces heart size in diabetic patients and reverses heart failure. The research led by Protemix demonstrates that defective copper metabolism is implicated in the development of heart disease.
A new process, Organ Recovery Systems, preserves transplant tissues/organs at refrigerator temperatures and minimizes damage from ice crystals. This technique reduces toxicity of cryoprotectants and enables long-term storage, potentially increasing organ availability worldwide.
NASA's TOPEX/Poseidon and Jason-1 satellites offer near-real-time lake water height data for 350 of the world's largest lakes. The US Department of Agriculture uses this information to manage irrigation and forecast crop production, particularly in areas with limited access to traditional water level gauges.
A new microfluidic device developed by NIST researchers can be used to make specialty polymers in small amounts or rapidly change polymer ingredients. This allows for systematic analysis of the impact of expensive additives on material behavior, which is crucial for applications in nanotechnology and biotechnology.
The Azithromycin and Coronary Events Study (ACES) found no reduction in cardiovascular events among participants treated with azithromycin. The study suggests that Chlamydia pneumoniae may not play a significant role in the late-stage development of coronary heart disease.
The landmark PROVE IT-TIMI 22 trial found that a long-term regimen of antibiotics designed to kill Chlamydia pneumoniae does not reduce the risk of heart attacks or cardiovascular disease. Researchers recommend focusing on proven therapies like high-dose statin therapy and ACE inhibitors instead.
Researchers at McGill University have identified a new gene, beta1-integrin, that plays a crucial role in the growth and development of breast cancer. Blocking this gene's function has been shown to halt tumour proliferation and prevent tumours from growing.
The trial found that early and aggressive statin use can reduce the long-term incidence of heart attacks, death from heart attack, stroke or readmission to the hospital for a cardiac event. However, benefits only became evident longer term, with no differences in endpoints during the first four months.
Preschoolers' diets have improved with increased servings of fruits, vegetables, and dairy products, but also saw a rise in added sugar and juice intake over the past 21 years. Children with healthier diets are less likely to be sick or overweight.
The American Physiological Society (APS) has awarded over $140,000 to minority students pursuing careers in physiology. These Porter Physiology Fellows are conducting innovative research projects that aim to improve our understanding of various physiological processes.
A study published in The Journal of the American Medical Association found that treating patients with recent acute coronary syndromes with higher doses of statins soon after experiencing heart-attack symptoms leads to a reduction in subsequent death, congestive heart failure, and other cardiac events compared to delayed treatment with...
The PNNL lab will develop a 'pulmonary physiome', a web-based model that provides predictive tools to understand the impact of airborne contaminants on human health. This project aims to improve treatments for asthma and other respiratory ailments.
A mouse study has identified a potential genetic link between NPAS3 and NPAS1 genes and psychosis. The mutated mice displayed deficits consistent with schizophrenia, including impaired social interaction and startle response. Further research is needed to confirm the connection.
A DNA mutation called 8-oxoguanine can evade detection by DNA replication enzymes, allowing it to persist in the DNA strand and potentially lead to stable incorporation of a lethal mutation. This discovery sheds light on how oxidative lesions affect DNA replication and has implications for cancer risk.
The European Society of Cardiology provides recommendations for athletes with cardiovascular disease, balancing risks and benefits of competitive sport. The panel aims to inform physicians and cardiologists about safe sport activities for candidates with cardiovascular abnormalities.
A recent study found that immediate statin therapy in hospitalized heart attack patients significantly reduced the risk of death and additional heart attacks. The study, which involved 3,605 patients at 260 medical centers, confirms earlier findings that early statin treatment is beneficial for heart health.
Researchers from MIT and international collaborations found that different proportions of two key ingredients in ginseng promote or hinder blood vessel growth, with implications for wound healing and cancer treatment. The study highlights the need for stronger regulations on herbal drugs due to variable processing methods.
Researchers discovered over 2,200 new human-specific Alu DNA repeats not found in chimpanzees, suggesting an explosive expansion of genetic code. This finding contradicts the idea of natural selection and highlights a chemical process driving human evolution.
The study group report emphasizes the need for systematic screening by 12-lead ECG to identify hypertrophic cardiomyopathy and other lethal cardiovascular diseases. The consensus document advocates for a common European screening protocol based on 12-lead ECG to prevent sports-related sudden death.
A new study suggests that early initiation of intensive statin treatment after a heart attack may lower the risk of future cardiovascular events. The research found that participants who received high-dose simvastatin had better outcomes than those on a placebo, despite an increased risk of muscle-related side effects.