The GlaxoSmithKline Drug Discovery and Development Research Grant Program provides funding for HIV/AIDS research, focusing on novel therapies, vaccines, and microbicides. Researchers can apply for grants ranging from $25,000 to $150,000 to develop innovative treatments and submit proposals for publication.
A recent study suggests that mycoplasma bacterial infections may cause or exacerbate asthma attacks in children. The research found that nearly half of children experiencing their first asthma attack were infected with mycoplasma. Testing for mycoplasma infection in asthmatic children could help prevent future attacks.
The study found that combination PET/CT correctly identified 94% of malignant lesions, but only 36% of benign nodules. It also showed that the technique accurately determined the stage of cancer in 61 patients, but may overstage or understage tumors.
A study found that furosemide inhalation alleviated severe breathlessness in patients with moderate to severe chronic obstructive pulmonary disease (COPD). Additionally, researchers developed a new model for neonatal bronchopulmonary dysplasia (BPD) using nasal continuous positive airway pressure (nCPAP) therapy.
John Alderete, a renowned microbiologist, has been recognized with the 2004 William A. Hinton Research Training Award for his tireless efforts to promote diversity in science. He is celebrated for mentoring dozens of graduate students and underrepresented minority groups, offering valuable advice and career opportunities.
Lovley's research focuses on the use of microbes to remove hazardous substances from environments, with applications in bioremediation and metal metabolism. His award recognizes his groundbreaking work on Geobacter species and their ability to reduce toxic metals.
Yahr's discovery of the type III secretion system in P. aeruginosa and its virulence factors holds promise for new vaccine candidates and treatments for patients with cystic fibrosis and AIDS.
Dhanasekaran has received the Raymond W. Sarber Award for his research on avian pneumovirus and Newcastle disease virus, which could lead to the development of recombinant vaccines against these diseases. His work aims to improve health and economic well-being in humans and animals.
Johnson-Thompson is recognized for her dedication to mentoring and increasing diversity in the field of microbiology. She has initiated various outreach initiatives, including a poster highlighting the contributions of women microbiologists.
Kiratisin's work introduces a novel technique for identifying viridans group streptococci, which can be misclassified by traditional methods. His research has essential clinical implications, particularly in treating infections caused by these organisms.
Campbell's groundbreaking research on bacteriophage lambda paved the way for studies on site-specific recombination and genome manipulation. His work has significantly advanced our understanding of microbial population dynamics and genome evolution.
Researchers found that long-term consumption of high amounts of isoflavones can alter patterns of agonistic and social behavior in primates, including increased aggressive and submissive behavior. The study suggests careful attention must be taken to balance beneficial and potentially adverse effects of soy consumption.
A team of researchers discovered a specific genetic mutation, Tbx10, responsible for causing cleft lip and palate in mice. This finding suggests that similar mutations may exist in humans, shedding light on the complex development of facial features.
Walsh's research on vancomycin resistance and bacterial synthesis has significant implications for future drug development. His work highlights the importance of understanding microbial virulence mechanisms to combat growing antibiotic-resistant threats.
Researchers at Penn State have found a missing chemical that plays a significant role in ozone and aerosol production in the lower atmosphere. The discovery was made through a two-year study of hydroxyl radical reactivity in a forested area, which found that a temperature-dependent chemical was reacting with the hydroxyl radical.
Betty Ann Forbes has made significant impacts in clinical microbiology and education through her extensive research, publication programs, and editorial work. Her leadership roles in the American Board of Medical Microbiology and esteemed journal publications have earned her a respected reputation among microbiologists nationwide.
Researchers at Yale University confirm the formation of dodecahedral water cages but find no evidence of the Eigen species. The study uses experimental techniques and supercomputers to determine how water molecules interconnect to form these cages, which play a crucial role in biological processes.
John Sherris is recognized for his tireless advocacy and leadership in clinical microbiology, including development of standardized susceptibility testing. He also holds an honorary medical degree from Karolinska Institute and has published a highly regarded textbook on medical microbiology.
Schiff's dedication to undergraduate education has led to numerous student awards and publications, as well as her election to the University of Minnesota's Academy of Distinguished Teachers. Her commitment to excellence in teaching and mentoring is recognized through the Carski Foundation Award.
ACTOS, an insulin sensitizer, is shown to improve diabetic dyslipidemia components when administered in combination with other diabetes therapies. The study found significant increases in average and peak LDL and HDL particle size, accompanied by a decrease in particle density.
Jennie Hunter-Cevera is a renowned microbiologist who has made significant contributions to the field through her innovative techniques for isolating and screening microorganisms. Her work has led to the discovery of new species, enzymes, and products, including antimicrobial, anticancer, and novel herbicidal properties.
In the 16th century, identity badges were issued to the poor as a stamp of approval and to prevent begging. The badges were designed to distinguish those deemed deserving from unworthy individuals. By the late 17th century, badging became compulsory in England, with penalties for those who refused to wear them.
Ferré-D'Amaré's groundbreaking research on RNA crystallization and ribozymes has significantly advanced the understanding of molecular structures in living organisms. He developed new techniques to obtain RNA crystals, enabling detailed studies of RNA-protein interactions and biochemical functions.
Rosmarin developed a new probe, the C-probe, to detect bacterial infections more accurately. This innovation has great promise for rapidly diagnosing serious infections like meningitis and improving patient outcomes.
The study reveals that strong magnetic fields accelerate particles near the speed of light, radiating as gamma rays. The research suggests a new mechanism for gamma-ray burst formation, potentially resolving long-standing scientific debates.
Researchers at Ohio State University have made a breakthrough in understanding how cells package DNA, with implications for cancer research and new therapies. A newly discovered protein, Hif1p, works with an enzyme complex to add histone proteins to DNA, forming chromatin.
Caroline Mohr, a leading expert in clinical microbiology, has won the 2004 Scherago-Rubin Award from the American Society for Microbiology. Her work involves identifying and classifying microorganisms, including gram-negative bacilli, and evaluating automated systems used to identify these bacteria.
Campbell's work on bacteriophage lambda demonstrated the relationship between its genome and host, leading to key findings in genetic and biochemical studies of site-specific recombination. His extensive contributions also include discovery of nonsense mutations, bacterial gene regulation, and microbial population dynamics research.
Jay Levy's research has significantly impacted our understanding of HIV and the immune system, leading to major breakthroughs in antiviral responses. His work has also improved the safety of blood products for hemophiliacs and shed light on the role of plasmacytoid dendritic cells in HIV infection.
Weissfeld's work on policy issues has had a significant impact on the profession of clinical microbiology. She chairs ASM's Professional Affairs Committee and serves on various committees reviewing legislation affecting microbiology laboratory practice.
Weinstein is recognized for his landmark articles on laboratory detection of bacterial and fungal infections, as well as his contributions to clinical decision-making in infectious disease medicine. He has also served on editorial boards of several journals and holds prestigious fellowships.
Vazquez-Torres is a leading researcher studying how Candida and Salmonella cause disease, and how the body fights off these pathogens. He has discovered new pathways by which cells can sample the intestinal lumen, migrate to the spleen, and trigger systemic immune responses.
A study of 160 pregnant women with genetic risk factors for thrombophilia found that enoxaparin significantly reduced pregnancy loss compared to low-dose aspirin. Women taking enoxaparin had a normal live birth rate of 86% and healthy newborns, while those on aspirin suffered more pregnancy losses.
The Mayo Clinic researchers have invented a nontoxic molecular probe that targets the brain regions containing amyloid plaques, enabling high-resolution MRI images in live mice and potentially human patients. The probe may also be used to evaluate new Alzheimer's therapies and provide early diagnosis.
A new measurement method and microenvironment evaluation technique have been developed to study spinal cord nerve regeneration. The findings extend earlier Mayo Clinic research, showing that a biodegradable scaffold can support axon growth under different experimental conditions.
A study reported in Journal of the American Dietetic Association found that between 1973-74 and 1993-94, the percentage of children eating a school lunch declined from 89.7% to 78.2%, while eating dinners prepared outside the home increased from 5.4% to 19%.
Jorge Escalante-Semerena has supervised 21 Ph.D. students, many of whom have won awards and fellowships. He is renowned for helping students gain recognition for their work, while also being a productive researcher focusing on cobalamin biosynthesis.
Researchers at MGH Cancer Center found that specific gene mutations in the EGFR gene predict responsiveness to Iressa, a targeted therapy that causes tumors to shrink significantly. The discovery will help determine which patients benefit from Iressa and potentially lead to new targeted therapies.
A recent study by Dr. Edward Scott and colleagues found that donor cells containing a Y chromosome were present in the brains of three women up to 6 years after bone marrow transplantation. This suggests that bone marrow could be used as a therapeutic source of readily harvestable cells for nerve cell regeneration.
King Chung's research shows that combining hearing aid technologies with cochlear implants reduces background noise, enhances speech understanding, and improves sound quality. Cochlear implant users prefer conditions with advanced hearing aid preprocessing.
Researchers use a NASA WB-57 research jet to examine icy cirrus clouds, aiming to understand their warming and cooling effects on Earth's climate. The Middle Latitude Cirrus Experiment gathers detailed information to improve computer simulations of future climate change.
HIV-infected women are 3.9 times more likely to have HPV infection at the outset of the study, and smoking significantly increases this risk. Smoking and HIV infection may each alter the natural history of HPV infection to heighten tumor risk.
Researchers have discovered a molecule called ppGpp that plays a crucial role in regulating bacterial gene expression and survival. When amino acid levels are low, ppGpp accumulates and shuts down protein synthesis, allowing the cell to go dormant until conditions improve.
Researchers identified a 23-gene signature that can predict disease recurrence in Dukes' B colon cancer patients with high accuracy. The study's findings have significant implications for personalized therapy decisions and could lead to improved patient outcomes.
Researchers have discovered a way to convert adult bone marrow cells into brain stem cells, which could potentially restore functioning in individuals with Alzheimer's disease. The process eliminates ethical and logistical issues associated with fetal tissue use and allows for quick conversion within a few weeks.
Researchers have successfully performed heart biopsies using arm catheterization, a promising new option for patients. The procedure showed no major complications and allowed patients to be discharged quickly.
Researchers studied 87 women with epilepsy and found that nearly 40% experience catamential patterns where seizures fluctuate with menstrual cycles. Progesterone lozenges may help reduce seizure frequency and severity during monthly hormonal changes.
Researchers developed a novel method to pinpoint rapidly evolving genes in pathogens, revealing potential drug targets for tuberculosis and malaria. The technique analyzes genome sequences to identify genes under selective pressure, allowing for the discovery of previously unknown genes.
Researchers linked mid-life heart disease risk factors to increased dementia risk later in life. The study of over 11,000 participants found that those with four key risk factors had nearly three times the chance of developing dementia compared to those with none. Presence of each risk factor added a 20-40% greater risk for developing ...
The report evaluates nine effective programs and eleven that warrant further research, highlighting the importance of defined outcomes, sustained commitment, personalization, challenging content, engaged adults, and educators' roles. These design principles aim to increase participation in STEM fields among underrepresented groups.
A recent study found that height loss of between 2-3 inches increases the risk of hip osteoporosis by nearly fourfold. Researchers suggest a simple evaluation of height can help physicians decide whether patients should undergo a bone density scan to check for osteoporosis.
A study published in Cell found that genetic defects in Nkx2-5 lead to progressive heart failure by degrading the electrical wiring of the heart, particularly the atrioventricular node. The researchers also identified a growth-factor gene called BMP-10 as a key contributor to this process.
A South African study found that women experiencing gender-based violence are more likely to contract HIV due to abusive partners imposing risky sexual practices. The research highlights the need for effective interventions to address social constructions of masculinity and intimate partner violence in relation to HIV risk.
Research found a direct correlation between viral levels in blood and semen, with acutely infected individuals being hyper-infectious before symptoms occur. Transmission rates during heterosexual sex are likely to be much higher than previously thought during this period.
A team of archaeologists has unearthed conclusive evidence of early humans' control over fire in Eurasia, dating back to the Acheulian culture. The discovery, made at the Benot Ya'aqov site in Israel, reveals that ancient humans used fire for cooking and warmth, significantly impacting their diet and survival.
Researchers at PTC Therapeutics have discovered a new biochemical pathway that controls cell growth modulation. This finding has significant implications for the development of therapeutics targeting cancer cells, which rely on deregulated translation to grow uncontrollably.
The article highlights the need for investment in human resources to respond to global health crises, particularly in sub-Saharan Africa. Human resources for health are essential for achieving better health outcomes, and donors can support these developments by acknowledging their importance.
Scientists at Georgia Tech Research Institute are developing a non-destructive radar system to detect mold behind walls, which can emit harmful compounds and cause serious health issues. The goal is to create a handheld prototype that can map mold and help contractors pinpoint damaged areas.
Experts question whether Europe can achieve ambitious environmental goals for children due to limited action taken. Prioritizing specific areas with clear disease causation and high burden is recommended.
Researchers at University of Pittsburgh successfully used suspension culture systems to promote follicular growth in rats and mice, showing promise for preserving ovarian fertility after cancer treatment. The study's findings suggest a promising step towards conserving fertility for cancer patients.