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Science News for April 12, 2004


Newer drugs appear to stem violent behavior

Researchers found that patients taking newer antipsychotics had less than one-third the incidence of violent behavior compared to those on older conventional medications. The study, which followed 229 patients with schizophrenia for two years, suggests that these medications may be more effective in reducing violence.

SourceDuke University Medical Center·JournalSchizophrenia Bulletin·DateApr 12, 2004

Continuous insulin monitoring does not raise hospital costs

A study published in Endocrine Practice found that continuous insulin monitoring and endocrinologist involvement did not increase the cost of treating diabetic patients undergoing CABG surgery. The protocol showed significantly better glycemic control, leading to shorter hospital stays and fewer deep sternal wound infections.

SourcePenn State·JournalEndocrine Practice·DateApr 12, 2004

Patients who receive kidneys from older donors do well

Researchers found that patients with kidney transplants from donors aged 55-79 had comparable allograft survival rates as those from younger donors. The study also revealed that older recipient patients may benefit from receiving kidneys from older deceased or living donors, particularly those facing prolonged waiting times on dialysis.

SourceJAMA Network·JournalArchives of Surgery·DateApr 12, 2004

Editorial: Blindness and visual impairment

The Eye Diseases Prevalence Research Group has conducted large, population-based studies to determine the prevalence of cataract, age-related macular degeneration, diabetic retinopathy, and other eye disorders. The estimates are likely to be reliable and available without waiting many years and spending tens of millions of dollars.

SourceJAMA Network·JournalArchives of Ophthalmology·DateApr 12, 2004

Embryonic skin cells committed at an early age

Researchers found that embryonic keratinocytes differentiate into skin cells much sooner than cells after birth. The study suggests a higher commitment to differentiation in embryonic skin cells, which may apply to other epithelial tissues.

SourceCell Press·JournalDevelopmental Cell·DateApr 12, 2004

Many patients interested in reading their own medical records

A study found that over a third of patients are interested in reading their medical records, with the most common reasons being to understand their condition and be more involved in healthcare. Patients who want to review their records are often those seeking alternative health information and have concerns about errors in care.

SourceJAMA Network·JournalArchives of Internal Medicine·DateApr 12, 2004

Extended lymph node dissection fails to increase long-term survival among gastric cancer patients

A study published in Journal of Clinical Oncology found that extended lymph node dissection does not increase long-term survival among gastric cancer patients, potentially increasing morbidity and hospital mortality. The procedure may only be beneficial if safe and effective alternatives can be developed.

SourceAmerican Society of Clinical Oncology·JournalJournal of Clinical Oncology·DateApr 12, 2004

New method is first to mimic subtle genetic changes

Researchers developed a new method to alter gene expression levels without disrupting essential control elements. This technique uses the 3' untranslated region (UTR) to influence protein production, allowing for predictable and controlled changes in gene expression.

SourceCell Press·JournalDevelopmental Cell·DateApr 12, 2004

American Thoracic Society Journal news tips for April 2004 (second issue)

Research suggests that community-acquired pneumonia patients who are discharged from the hospital may face a higher risk of mortality in the subsequent 2-3 years if they have certain predictors, such as increasing age and cardiovascular disease. The study also found no excess mortality in younger patients without accompanying diseases.

SourceAmerican Thoracic Society·JournalAmerican Journal of Respiratory and Critical Care Medicine·DateApr 12, 2004