A new study shows that Seroquel achieves remission in bipolar mania, with a significant increase in remission rates over time. The medication has been shown to be effective in reducing symptoms of racing thoughts, reckless behavior, and decreased sleep.
Scientists have identified genetic mutations in heat shock proteins linked to Charcot-Marie-Tooth disease, a debilitating disorder affecting peripheral nerves. The study's findings hold promise for developing new therapies and improving diagnosis.
A study by Gabriella Milos and colleagues found that women with anorexia were more likely to have suicidal thoughts than those with bulimia or other disorders. The researchers also discovered a link between purging behaviors and increased suicide risk, suggesting a possible connection to lack of impulse control.
Researchers at Yale University found that losing a job near retirement age significantly increases the risk of stroke. The study, which analyzed data from six years of the national Health and Retirement Survey, identified 457 workers who were either laid off or left jobless due to a plant shutdown.
A study by RTI International and the Mayo Clinic found that calibration errors in calcium laboratory tests can add up to $89 per patient, affecting approximately 3.55 million patients and increasing healthcare costs.
The Emory research team will model disease outbreaks in hypothetical American communities to find the best methods of controlling epidemics. They will also investigate the interaction of microorganisms with the immune system and its relation to disease spread.
A researcher has identified a genetic abnormality affecting American DFNA9 syndrome patients also present in Dutch families, including BOR syndrome, leading to valuable insights into the progression of diseases. The discovery highlights the importance of gene matching research for identifying new candidate genes.
A new study led by Duke University and NIST found a correlation between sea turtle health and high levels of toxic organic chemicals. The research team analyzed blood and fat samples from 48 juvenile turtles in North Carolina waters, discovering changes in immune function, liver damage, and protein regulation.
Researchers have translated 43 hymns from the Atharvaveda into English, providing insight into centuries-old rituals. The hymns, written in Vedic Sanskrit, were used by priests to venerate gods, heal diseases, and exorcise evil spirits.
Astronomer Steve van Straaten discovered a binary star with a vibrational frequency of 1330 Hz, the highest ever recorded. This finding allows researchers to develop new models for movement in the vicinity of a neutron star.
Research at Vanderbilt University found that dopamine transmission increases in response to uncertain reward scenarios, such as gambling. The study used PET scanners to measure brain activity in nine human subjects and discovered localized regions showing increased or decreased dopamine release.
A study at the University of Pittsburgh Medical Center found that paroxetine significantly improved bowel movements and food avoidance in participants with irritable bowel syndrome. The drug relieved some symptoms of IBS and showed improvement in overall well-being, particularly in those without depression.
Recent research suggests that autoantibodies can identify individuals at risk of autoimmune diseases such as rheumatoid arthritis and diabetes. Autoantibodies were detected in healthy individuals years before the onset of symptoms, paving the way for potential preventive treatments and improved disease management.
Researchers aim to develop AI system that can assess acoustic qualities of spaces using music played in the room. The project has £70,000 funding and could provide solutions for architects and the construction industry.
Researchers have identified critical stretches of ultra-conserved DNA sequences in the human genome, found near well-studied genes and involved in regulating transcription. These elements were also conserved across multiple species, including rats, mice, chickens, and even ancient genomes like those of sea squirts and roundworms.
A recent multi-center trial has shown cryoablation to be effective in killing cancerous cells in small tumors, offering a promising alternative to traditional surgery for early-stage breast cancer. The study found that the procedure was equally effective for tumors between 1.0 and 1.5 centimeters in diameter, but not larger than 1.5 cm.
A phase III study presented at the American Psychiatric Association Meeting found that ADDERALL XR improves ADHD symptoms for up to 24 months. The medication reduced symptoms by an average of 45% in patients who received it consistently, with a significant reduction in inattention and impulsivity subscales.
Researchers at Lund Institute of Technology have created nanoscale trees using controlled seeding, enabling complex structures for various applications. The technology offers potential for converting sunlight to electricity and creating efficient light panels.
The discovery of modern hummingbirds in Europe pushes the fossil record back approximately 29 million years and zips halfway around the world. The tiny skeletons found in southern Germany exhibit characteristics such as tiny size, long beaks, and wing design similar to today's hummingbirds.
Researchers at UCLA deciphered the mystery of distant memory recall using a three-pronged experiment. They found that the anterior cingulate plays a special role in keeping early memories alive, while kinase II is critically involved in preserving our oldest memories.
A study by OHSU found that methylphenidate, Ritalin, increases the effects of levodopa on dopamine levels, improving symptoms such as tapping and walking speeds. In contrast, paroxetine had no effect on physical symptoms but increased walking speed in Parkinson's patients.
A survey of adults reveals long-term consequences of ADHD, including lower educational achievement, relationship instability, and higher rates of stress, depression, and substance abuse. Adults with ADHD are also more likely to experience negative self-image and engage in harmful behaviors.
Researchers at McGill University have developed three computer games that can help people feel more positive about themselves and build their self-esteem. The games, Wham!, EyeSpy: The Matrix, and Grow Your Chi, work by training players to focus on positive feedback and develop automatic thought patterns that boost confidence.
Researchers have discovered that the anterior cingulate cortex plays a crucial role in storing and retrieving lifelong memories. The study, led by Dr. Paul Frankland, found that older memories are transferred from the hippocampus to the cortex over several weeks, likely during sleep.
A new CAD system has been shown to detect 77% of computer-identified false positives, leading to more accurate polyp detection. The technology holds promise for increasing widespread colon cancer screening due to its ability to significantly reduce the difficulty and time required for exam interpretation.
Researchers discovered that choroid plexus cells can stimulate stem cell production and release neurotrophic factors after a stroke, reducing damage in animal models. The study suggests potential for new therapy to supplement the natural healing response of this tissue.
A giant fossil coral found in Vanuatu provides evidence of the Younger Dryas period's significant cooling event, which affected the tropics. The coral's growth rate and chemical composition reveal that sea surface temperatures were on average 4.5°C lower than present during this time.
The Max Planck Research Prize recognizes the work of Martin Vingron and Eugene W. Myers in bioinformatics, enabling precise gene expression analysis and tailored therapies. The prize honors international cooperation in this field, providing significant research funding.
A new study found that MRI is more effective than PET in detecting small liver metastases, with an accuracy rate of 75.5%, compared to PET's 64.1%. The study used a custom liver-specific contrast agent, which improved image resolution and detection of smaller lesions.
Researchers found that surgery to remove fatty deposits from narrowed vessels can significantly reduce stroke risk, with a 50% reduction in strokes among those who underwent the procedure. The study's results confirm previous findings and highlight the need for more adults to be screened for narrowed carotid arteries.
A study by Wake Forest Baptist found that eszopiclone significantly improved sleep measures in older adults with insomnia, including reduced napping and enhanced quality of life. The treatment increased total sleep time and reduced the tendency to wake up repeatedly during sleep.
Researchers discovered 481 ultra-conserved elements in the human genome, which are long and evolutionarily frozen. These elements are associated with genes, particularly those involved in regulating gene expression through alternative splicing.
Researchers found that simple public health measures can contain highly transmissible diseases like SARS and smallpox. In contrast, moderately transmissible viruses like HIV and pandemic influenza require more complex control measures due to early symptom onset.
Researchers have developed a second-generation targeted antibody, 806, which shows potent anti-tumor activity in animal models of human cancers that overexpress EGFR. The antibody binds specifically to activated EGFR on cancer cells, avoiding normal tissues.
A study found that over half of men taking part in a prostate cancer risk assessment program reported using dietary supplements to prevent the disease. The most commonly used supplements were vitamins and minerals, with saw-palmetto being one popular option.
The guidelines provide a rigorous analysis of the safety, efficacy, and mode of use of new antiepileptic drugs, offering clinicians evidence-based assessments for treatment decisions. The guidelines address concerns about side effects and liver metabolism, providing guidance on using newer drugs safely and effectively.
A study found that highly processed isoflavone products may pose a risk to postmenopausal women with estrogen-responsive breast cancers. Minimally processed soy flour was associated with less tumor growth in mice, suggesting a potential health benefit for consumers of whole soy foods.
A Georgia Institute of Technology study found that older adults are willing to sacrifice some privacy for technologies that enable them to live independently longer. The study evaluated various technologies, including Cook's Collage and FaceBot, which sparked both positive and negative reactions among participants.
A study found that MRI scans can detect breast cancer in 70% of cases at stage 1, and in 62% of cases without a mass. Most women who underwent the test chose mastectomy due to early detection.
The KRONUS-MSP trial found that switching to sustained-release opioid Kadian improves pain relief and quality of life, while reducing the need for medication. Patients who previously exceeded recommended doses of OxyContin or MS Contin found relief with Kadian.
A study by Lund scientists has shown that adult stem cells cannot form new heart muscle cells after a heart attack. The transplanted cells retain their identity as blood cells and fuse with heart muscle cells outside the infarcted area.
UVa researchers have identified a gene, Stat-4, that plays a key role in the development of type 1 diabetes. Disrupting this gene may help prevent the disease, and a new anti-inflammatory compound, Lisofylline (LSF), has shown promise in inhibiting its activation.
A study by OHSU researchers has identified genetic defects in five genes as responsible for a minority of unexplained sudden cardiac deaths. The findings provide hope that gene defects may also have caused remaining deaths and bring closer to predicting who is vulnerable to sudden death.
Researchers studied 40 patients with 42 adrenal masses and found that MRI was more sensitive than CT in characterizing lipid-rich adenomas. The study's findings suggest that MRI may be the preferred imaging modality for detecting adrenal adenomas, particularly in cases where symptoms are present or a history of cancer is known.
A study found that 28% of Central Valley sediment samples are toxic to amphipods and midge larvae due to pyrethroids. The pesticides were present in 68% of these sediments, posing a risk to freshwater organisms.
The BOLDER study found SEROQUEL to be superior to placebo in reducing depressive symptoms and anxiety in patients with bipolar disorder. Approximately 50% of patients achieved remission from their bipolar depression symptoms.
Researchers found that taxanes significantly improved immune function in breast cancer patients, with a 37% increase in T cell growth and a 39% boost in NK cell activity. The study's findings suggest that taxanes may improve patient outcomes or quality of life by enhancing the body's ability to respond to infection or cancer recurrence.
The President's Awards for Excellence in Science, Mathematics, and Engineering Mentoring recognize institutions and individuals who promote diversity and inclusion in STEM education. This year, 62 institutions and 78 individuals were recognized for their innovative approaches to mentoring, including comprehensive programs and community...
A randomized double-blind cross-over study involving 22 healthy volunteers found that Malarone(TM) had no significant effect on vigilance, alertness, or quality of sleep. The results support previous studies showing Malarone(TM) has no impact under normal pressure conditions.
A Texas A&M University researcher is studying a large dead zone in the Gulf of Mexico, where fertilizers are suspected to be a major cause. The Mississippi River is creating a perfect storm for these chemical runoff events due to its massive size and high nutrient levels.
A nationwide study by University of Florida professor Brian Stults found that housing segregation between racial groups persisted in many parts of the nation, with blacks and whites experiencing high levels of separation in neighborhoods, schools, and income distribution
Researchers from Wake Forest University Baptist Medical Center and Wake Forest Health found a 24% improvement in physical function among participants who combined weight loss with moderate exercise. Participants reported significant improvements in knee pain, with a decrease of over 30%.
The Wildlife Conservation Society recently rounded up over 300 threatened flamingos in the Altiplano region, collecting data on their health and tracking population trends. The organization has been participating in a banding project for three years, working to conserve vulnerable species like James' and Andean flamingoes.
A new protein, DEFB118, has been discovered in the male reproductive tract and has potent antibacterial activity. It may aid fertilization by protecting sperm from harmful organisms encountered in the female reproductive tract.
A recent study found that carotid endarterectomy (CEA) significantly reduces the risk of stroke among high-risk patients. The 5-year risk of stroke was around half for patients under 75 years old given CEA compared to those receiving no intervention. However, the benefits of immediate surgery may be short-lived, and ongoing follow-up i...
A study found that NICE guidelines on surgical procedures had no significant impact on the adoption of recommended practices. In contrast, an increase in non-cement prostheses for hip replacements was reported after the guidelines were issued. The researchers suggest using more active dissemination methods to promote effective uptake.
Researchers from Case Western Reserve University School of Medicine have discovered that RNA helicases can displace proteins from single-stranded RNA and change shape without unwinding duplexes. This finding redefines the mechanism of action of RNA helicases, providing new insights into their roles in various biological processes.
End-user programmers, estimated at 55 million by 2005, create nontrivial bugs nearly half of the time. Researchers from U.S. National Science Foundation develop new techniques and tools to aid debugging, focusing on 'negotiated' interruptions and novel environments that ask questions about code behavior.
Researchers used gene therapy to increase dopamine D2 receptor levels, reducing preference for alcohol and consumption by half in genetically predisposed rats. The treatment showed significant reductions in drinking preference and consumption in both groups, with the greatest effects observed within days of treatment.
Researchers used the MIDI instrument in the VLTI Laboratory to study the central region of active galaxy NGC 1068. They confirmed the presence of a torus-shaped structure of gas and dust around the black hole, with a hot inner zone and a cooler outer region.