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Science News for August 1, 2004


In search of a lean gene

Researchers at Cold Spring Harbor Laboratory discovered a lean gene, C/EBPbeta, which helps mice live longer and weigh less. The gene's activation may help jump-start metabolism in fat cells, preventing fat accumulation. Another study found that targeting the JIP1 protein can effectively protect against obesity and insulin resistance.

SourceCold Spring Harbor Laboratory·JournalGenes & Development·DateAug 1, 2004

Pioneering the basics for new kind of cancer vaccine

Scientists at Mayo Clinic develop novel approach to cancer vaccine that leverages inflammatory cell death to trigger a strong anti-tumor immune response, eradicating skin cancer tumors without triggering autoimmune disease. The breakthrough sheds light on a major obstacle in advancing cancer vaccine research from lab to human trials.

SourceMayo Clinic·JournalNature Biotechnology·DateAug 1, 2004

DNA variations surprise researchers

Researchers using new genome scanning technologies found stretches of DNA varying by hundreds of thousands of chemical bases that were present or absent in healthy individuals' genomes. This challenge long-held beliefs about the limited nature of genetic variation.

SourceUniversity of Toronto·JournalNature Genetics·DateAug 1, 2004

Radiofrequency ablation safe and feasible for eradicating lung tumors

In a study of 18 patients with inoperable lung tumors, radiofrequency ablation (RFA) was found to eradicate lung tumors with no relapse in 94% of cases. Minor complications, including pneumothorax, were treated successfully, and the procedure offered benefits such as low costs, short hospitalization times, and good patient tolerance.

SourceAmerican College of Radiology·JournalAmerican Journal of Roentgenology·DateAug 1, 2004

Lehmann lovegrass won't succumb to fire

Researchers at the University of Arizona found that Lehmann lovegrass, an invasive species introduced in the 1930s, remains unchanged despite controlled burns. The study suggests that fire is not effective in reducing the spread of non-native species, forcing land managers to explore alternative methods for controlling the invasive grass.

August 2004 Ophthalmology journal

The Los Angeles Latino Eye Study investigated the prevalence of open-angle glaucoma and ocular hypertension in Latinos. The study also explored changes in retinal nerve fiber layer thickness after acute primary angle closure. Additionally, researchers examined the impact of cataract on frequency-doubling technology perimetry results.

SourceAmerican Academy of Ophthalmology·JournalOphthalmology·DateAug 1, 2004