A large trial found that interferon gamma-1b did not slow the progression of pulmonary fibrosis, but may improve survival in early-stage patients. The treatment's failure to prevent lung scarring was a major concern.
Scientists create cell chips using temperature-driven changes in a material, enabling the creation of custom-designed devices for experiments and medical applications. The technology has the potential to revolutionize tissue engineering and medical diagnostics by providing a low-cost, efficient way to create complex devices.
Researchers at the University of Wisconsin-Madison have identified a key gene that regulates flowering in biennials, such as carrots and cabbage. The discovery could lead to new methods for manipulating crop productivity and understanding how organisms control cell fates during development.
A new synthesis method for sodium cobalt oxyhydrate, a type of superconductor containing water, has been developed by Brookhaven chemist Sangmoon Park. This method produces large quantities of the material without requiring hazardous substances, making it easier to further analyze its properties.
Researchers at Rockefeller University have developed a feeder-free system for maintaining pluripotency in human embryonic stem cells, overcoming the need for mouse feeder cells. The system uses a synthetic compound derived from a marine mollusk to activate the Wnt signaling pathway, keeping stem cells in an active, undifferentiated state.
A review article by Daniel B. Di Giulio and Paul B. Eckburg reports the first confirmed cases of monkeypox in the US, likely introduced through the pet trade and rodent importation. The disease has been mild in the US, with no fatalities, but poses a risk of endemicity in US rodent populations.
University of Central Florida researchers are testing a new way to communicate with soldiers through vibrations, aiming to reduce distractions and improve safety. The study, funded by the U.S. Department of Defense, explores whether coded vibrations can be an effective alternative to traditional communication methods.
A study predicts that climate change will put 15-37% of species in biodiversity-rich regions at risk of extinction by 2050. The study used computer models to simulate the impact of changing temperatures on species distributions, and found that well over a million species could be threatened with extinction.
Researchers at Northwestern University have made a breakthrough in treating Alzheimer's disease by targeting the gene that causes memory loss. The study found that inhibiting an enzyme called BACE1 can prevent memory deficits and brain cell functional abnormalities in laboratory models of Alzheimer's disease.
A study by Oregon Research Institute found that cobblestone mat walking improves pain relief and mental well-being in older adults. Participants who walked on the cobblestone mat experienced enhanced physical activity and reduced stress levels compared to those in an attention control group.
Researchers found that nanotubes with tiny bumps cause less scar tissue and stimulate neurons to grow more fingerlike extensions, needed for brain activity regeneration. The findings suggest using a mixture of plastics and nanotubes could decrease scar tissue formation around electrodes.
The University of California - San Diego Medical Center has been awarded a contract by the NIH to create a national tuberculosis educational curriculum. The goal is to raise awareness and improve education on TB, which can be controlled with effective medications. The consortium includes faculty members from 12 medical schools, six nur...
Researchers at Johns Hopkins Medicine have identified two new alleles and four existing ones among the Lakota Sioux tribe, increasing the likelihood of finding compatible organ donors within their population. This study could facilitate transplantation in Native American populations with high rates of diabetes and end-stage renal disease.
Researchers found high concentrations of BDEs in peregrine falcon eggs, suggesting the deca formulation may not be harmless. The study's findings add to concerns about the safety of BDEs and their potential impact on wildlife.
The honey bee genome has been assembled through a team-led effort by the NIH/National Human Genome Research Institute. With approximately 300 million DNA base pairs, it is one-tenth the size of the human genome. Researchers aim to compare the genome with other organisms to understand genes and regulatory regions within DNA.
A recent study found that a new, experimental injectable sustained-release depot formulation of buprenorphine is safe and effective in treating narcotic addiction. The treatment provides long-term benefits, reducing opioid withdrawal symptoms and sensitivity to opioids.
Researchers have discovered a link between the ratio of two energy-compounds and increased blood flow in brain cells. By modulating this ratio, scientists can better understand how blood circulation is activated in the brain, potentially leading to new treatments for diseases like Alzheimer's and diabetes.
A recent study found a significant association between the breakdown of the vitreous gel and the development of nuclear cataracts. The researchers discovered that high levels of vitreous liquefaction were strongly correlated with cataract formation, even after accounting for age.
Researchers at UCSD found that blood pressure measurements vary significantly depending on the arm position used. The study measured blood pressure in 100 emergency room patients and found systolic and diastolic pressures to be lower with arms perpendicular to the body than parallel to it, affecting hypertension classifications.
Children with hyperlexia display exceptional reading skills, often exceeding their age, yet struggle with social interactions. FMRI studies reveal distinct brain activity patterns, highlighting the neural mechanisms underlying this rare condition.
Researchers create new microfluidic chip assembly method using glass microscope slides, tweezers, and a flexible polymer, cutting design and manufacture time from weeks to hours. The new approach enables scientists to test ideas quickly and conduct research in typical laboratories.