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Science News for March 21, 2004


'Library on a Slide': Whole genome microarrays for comparative genomics

Researchers developed 'Library on a Slide' technique to compare bacterial genomes, allowing for efficient identification of genes associated with biological processes. The method involves printing genomic DNA at high density onto a glass slide and uses fluorescently labelled probes to detect target genes.

SourceBMC (BioMed Central)·JournalBMC Microbiology·DateMar 21, 2004

Researchers discover novel form of the Rett Syndrome protein

A new form of the MeCP2 protein has been discovered, which may be more important in causing Rett Syndrome. The protein is found to be more abundant in the brain and its function must be understood to relate it to the disease symptoms.

SourceRett Syndrome Research Foundation·JournalNature Genetics·DateMar 21, 2004

Stem cells appear not to turn into heart cells

Research suggests that bone-marrow-derived stem cells do not differentiate into new heart muscle cells when injected into damaged hearts. Instead, they mature into traditional blood lineage cells. This challenges the idea of using stem cell therapy to repair damaged hearts and raises questions about alternative approaches.

SourceIndiana University·JournalNature·DateMar 21, 2004
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Blood-forming stem cells fail to repair heart muscle in Stanford study

Researchers found that blood-forming stem cells lodge in damaged hearts but retain their blood-forming fate, contradicting earlier findings. The study suggests that these cells may not be able to transform into muscle cells, but could still offer some potential for treating heart attack patients

SourceStanford Medicine·JournalNature·DateMar 21, 2004
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