Researchers have identified the Dido gene as a potential tumor suppressor involved in myeloproliferative diseases. The study found that 100% of patients with these diseases had Dido expression abnormalities, suggesting a link between the gene and the development of MDS/MPD.
A survey of UK hospital consultants found a significant increase in poor mental health and burnout, attributed to increased job stress and workload. The prevalence of psychiatric illness rose from 27% in 1994 to 32% in 2002, with clinical oncologists facing the greatest increases.
Researchers discover crystal structure of cyan fluorescent protein, leading to understanding of coral reef coloration. The study provides insight into the biological function of coral reef coloration and its potential connection to environmental stresses.
Researchers at the University of Arizona have developed a theory explaining why nanowires thin away at non-zero temperatures. The discovery reveals that higher surface tensions stabilize the wires, making them suitable for repeated use. Copper is identified as the best metal for creating stable nanowires.
Research shows that limiting episiotomies can lead to less perineal trauma, fewer need for suturing, and fewer postpartum complications. Episiotomy rates vary widely across countries and regions, with the US having a higher rate than many other English-speaking countries.
A recent study published in Nature Structural & Molecular Biology has identified a key protein, Upf1, that regulates histone production during cell division. The research suggests that an imbalance in DNA and histone production is lethal for cells and may be crucial in understanding tumor growth.
Researchers identified a genetic link between inflammation and an increased risk of stroke after heart surgery. A specific combination of polymorphisms in genes responsible for C-reactive protein and interleukin-6 was found to be associated with a higher rate of stroke in patients.
The National Foundation for Cancer Research (NFCR) and the Prostate Cancer Foundation have partnered with the Burnham Institute to develop a 3D culture system that simulates tumor microenvironments. This technology enables rapid testing of candidate drugs and has potential applications beyond cancer research.
A recent archaeological comparison of genetic traits indicates that Moche sacrificial victims were not local elite, but rather warriors captured from nearby valleys. This finding suggests territorial conflict and competition among Moche populations in each valley.
Researchers discovered a new protein, MAVS, located in the mitochondrial membrane that plays a vital role in immune defense against microbial infections. The study suggests that variations in MAVS expression levels may endow individuals with varying ability to fight off viral diseases.
A study published in Cell reveals that PGC-1 alpha, a metabolic regulator, plays a crucial role in the development of porphyria symptoms. Fasting and certain drugs can trigger attacks, which can be treated with high-carbohydrate diets and glucose feedings.
Scientists have found evidence that dust from burning asteroids can influence local weather in Antarctica, forming clouds of micron-sized particles that reflect sunlight and cause cooling. This discovery challenges previous assumptions about asteroid dust's impact on the environment.
A study by Professor Andrew Gamble found that child trust funds are an important and unusual universal benefit. Young people strongly support the principle of capital grants but want greater restrictions on how money is spent, with a focus on higher education and starting a business.
A study of 110 homoeopathy trials and 110 conventional medicine trials found that smaller, lower-quality trials showed more beneficial treatment effects for homoeopathy. However, larger, higher-quality trials revealed no significant evidence that homoeopathy was superior to placebo.
A randomized controlled trial found that parenteral artesunate reduced mortality from severe malaria by 15% compared to quinine, while also being safer and simpler to administer. The study calls for quality-assured, affordable artesunate to be made widely available in malaria-endemic areas.
Scientists use AFM and STM to study frictional force in decagonal quasicrystals, revealing strong connection between interface structure and dissipation. The results show that friction is greater along the periodic direction, with an anisotropy of up to 8 times greater than in the aperiodic direction.
Researchers found a strong association between orexin neurons and reward seeking behavior in rats. Orexin activation reinstated extinguished drug-seeking behavior and was related to preferences for cues associated with rewards.
The Abuja Declaration endorses a five-point strategy to support capture fisheries, develop aquaculture, improve fish market chains, increase benefits from fish trade, and provide decision makers with information. African fish and fishery products have an annual export value of $2.7 billion.
Research suggests that high blood lactate levels can accurately predict a poor outcome in patients with fulminant hepatic failure (FHF). The study examined the relationship between serum phosphate and lactate levels in FHF patients, finding that lactate levels were significantly higher in those who died or underwent a transplant.
A new dye, NIAD-4, has been developed to allow direct imaging of Alzheimer's plaques through a patient's skull without invasive procedures. The compound binds to amyloid brain plaques and fluoresces when exposed to near-infrared radiation, providing clear visual images.
Aphids vary in their resistance to wasp parasitism, but new research suggests that the difference lies in the symbiotic bacteria carried inside them. Carrying these bacteria reduces parasitism by up to 40% and demonstrates a heritable form of acquired resistance.
Researchers found evidence for differential rotation of Earth's solid inner core, with the core rotating faster than the surrounding mantle and crust. The discovery suggests electromagnetic coupling is driving the inner core's motion, generating an electric current that causes it to spin.
Researchers found that the protein Klotho extends lifespan in mice by making them resistant to insulin, but also increases risk of diabetes. The study offers promising hope for developing anti-aging therapies.
A protein-rich diet combined with exercise leads to greater weight loss and fat reduction compared to a high-carbohydrate, lower-protein diet. This study found that dieters on the protein-rich diet lost almost 100% of their weight in fat, while those on the low-protein diet lost 25-30% of their weight as muscle.
Researchers discovered a gene, PfRh4, that enables P. falciparum parasites to switch between two invasion pathways, increasing their adaptability in the face of immune responses and host changes. This finding has important implications for the design of anti-malaria vaccines.
Researchers found that antibiotics are less effective in preventing recurrent gastric lymphoma when H. pylori is re-infected, and that follicular dendritic cells play a key role in the disease's progression. Re-infected animals developed more aggressive tumors than those who received antibiotic treatment.
UQ researchers received top honors in e-research grants, developing AI for breast cancer detection and improving data management. The university's initiative aims to overcome barriers to E-Research adoption.
The study found that farmers who participated in workshops made better decisions in response to good information, resulting in improved crop yields. The researchers also found that the workshops increased the use of forecast information among farmers, particularly those in subsistence farming.
Researchers found that DNA dissipates ultraviolet energy through a wave-like process along its edge, rather than damaging base pairs. This new understanding sheds light on the DNA repair process and has implications for biology.
The Phase II clinical trial of belatacept found that it preserved kidney function and reduced the incidence of acute rejection in transplant patients. Belatacept selectively blocks T-cell activation while allowing the body to fight off infections.
Researchers will study chemical reactions and transformation of mercury in flue gases of coal-fired power plants. They aim to develop a mathematical model to predict mercury emissions and create more effective technologies for controlling mercury emissions.
Researchers at Georgia Institute of Technology have pinpointed a chemical called triazole that can allow polymer electrolyte membrane (PEM) fuel cells to operate at much higher temperatures without moisture. This discovery could make polymer fuel cells cheaper and more practical for use in cars, laptops, and cell phones.
The study found that subjective responses to cocaine peak and decline more rapidly than those of methamphetamine. Cardiovascular responses are similar at onset but respond differently over time.
Researchers found that mothers with dental caries who had C-section births passed a specific bacterium to their babies, leading to an earlier onset of cavities. The study suggests that family dentists should inform patients about the potential risk if they had a C-section delivery.
A recent study found that TV ads marketed high-sugar and unhealthy foods to children, dominating nearly 44% of the airtime. The research also revealed that convenience/fast foods made up 34.2% of the advertisements during kids' favorite TV programs.
Researchers discovered the structure of miniature motors in muscles and found out how they are switched off. By studying tarantula striated muscle, scientists created a detailed model of the myosin heads and their interactions with actin filaments.
A recent study published in Psychological Science found no indication of a bisexual pattern of genital arousal among heterosexual and homosexual men, but did reveal a distinct bisexual pattern of subjective arousal. This challenges the existing understanding of male bisexuality and highlights the need for further research.
Researchers at Rutgers University have identified the protein snapin as having therapy potential for autism by modulating dendrite patterning. Snapin's interaction with cypin regulates branching, and targeting this pathway could lead to new drugs.
A meta-analysis of 15 studies reveals that spina bifida causes significant psychological distress in parents, particularly mothers. The condition's impact on families requires healthcare to include psychological support for caregivers to cope with childcare and ensure family well-being.
The discovery of a diuretic hormone in malaria mosquitoes could lead to the development of a pesticide for controlling mosquitoes. The hormone, DH31, causes the mosquito to excrete fluid rich in sodium chloride, potentially leading to its death.
A new study by the European Society of Human Reproduction and Embryology found no correlation between psychological stress and IVF success rates. The research, based on extensive questionnaires, showed that patients' well-being prior to treatment had no impact on their chances of conceiving.
Researchers at VCU demonstrated that a cytokine called interferon gamma can induce the death of developing mast cells in a mouse model system. This finding may lead to the development of new treatments for allergy and inflammatory responses in diseases such as arthritis, multiple sclerosis, and heart disease.
The Government of Canada has invested $2.8 million to fund 13 health research projects on childhood obesity, which affects 26% of Canadian children aged 2-17. The projects will focus on creating healthy, active schools and developing programs to tackle the issue.
U-Iowa researchers aim to find genes and pathways that protect against toxic effects of alcohol on the fetus. The two-year study will utilize neonatal rodents to examine the role of vasoactive intestinal peptide in fetal brain development.
A study examining media reports on the closure of HIV drug trials in Cambodia and Cameroon found that many articles failed to identify primary sources or provided inaccurate information. The researchers stress that both the media and trial organisers have a responsibility to provide accurate information during periods of controversy.
Researchers at the Hebrew University of Jerusalem have discovered that the brain regulates bone density by controlling the activity of interleukin 1 protein. This finding holds promise for developing new treatments for osteoporosis.
Researchers used the Community Climate System Model (CCSM) to study the Permian extinction event, which saw 90-95% of marine species and 70% of terrestrial species die. The model found that warming ocean waters at higher latitudes due to rising CO2 levels led to a stratified ocean with little oxygen, making it deadly for marine life.
A study by Dr. Johanne Paradis found that immigrant children's English skills are comparable to those of monolingual children with speech language impairment, leading to potential misdiagnosis and unnecessary referrals to therapy services. This phenomenon is a concern for many countries, including Canada, the US, UK, and Australia.
A unique program at Stevens Institute of Technology addresses the need for in-depth understanding of sourcing's four key aspects: governance, legal issues, relationship management, and organizational impact. Preliminary research aims to understand current and future IT skills and capabilities needs.
Researchers Cornelia Class and Steven L. Goldstein re-evaluate geochemical arguments using new databases, finding evidence favors whole-mantle convection. This supports the idea that most of Earth's mantle has been subject to the same forces driving crust movements.
A team of scientists found that coral populations were healthy until the 1980s when they were killed by disease and high sea temperatures. Addressing global environmental issues like climate change is crucial for saving coral reefs.
A study published in JAMA finds that rapid heroin detox under anesthesia can lead to death, psychosis, and increased stress. Alternative methods such as buprenorphine and clonidine are more effective and less expensive, highlighting the need for safer treatment options.
Researchers at Queen's University have developed switchable solvents that enhance chemical manufacturing processes while minimizing waste and emissions. This breakthrough enables more environmentally-friendly chemical production methods.
The Virginia Tech EIGER project focuses on naturally occurring interfaces among minerals, water, air, and microorganisms. The program will educate graduate students in a complex field vital to leading environmental issues through an interdisciplinary approach.
Researchers have created a handheld device that uses two-photon microendoscopy to image individual cells in living subjects, enabling insights into cellular behavior and its impact on organisms. The technique has been successfully demonstrated using live mice, providing detailed images of blood vessels in the hippocampus.
A Mayo Clinic study found acupuncture significantly improves symptoms of pain, fatigue, and anxiety in patients with moderate to severe fibromyalgia. The treatment showed promise as an additive therapy to existing medications.
Researchers used seismic data to create images of solidified lenses and sills embedded in the Earth's crust/mantle boundary, suggesting a complex formation process. The findings imply that the lower oceanic crust is generated from multiple smaller magma sources rather than a single large source.
Researchers have released new audio recordings of ivory-billed woodpeckers, showing striking similarities to existing evidence. The findings suggest a high probability that multiple birds exist in the area, providing additional hope for the species' survival.
Belatacept demonstrates improved kidney function and reduced toxicity in patients undergoing kidney transplantation. The treatment reduces the need for immunosuppressive medications and minimizes chronic allograft nephropathy.
A study published in JAMA Network found that a diagnostic strategy combining Transesophageal ultrasound-guided fine needle aspiration (EUS-FNA) and mediastinoscopy can identify more patients with tumor invasion or lymph node metastases, reducing unnecessary thoracotomies by 16%.