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Science News for November 18, 2005


Polymer gel can block toxic leakage problem in gene therapy

Researchers have developed a biocompatible polymer that briefly changes from liquid to gel at body temperature to block gene-bearing viruses from leaking into the bloodstream and harming other tissues. This method reduces misdirected virus dissemination by a factor of 100-1,000 times, solving the problem of toxic leakage in gene therapy.

SourceDuke University·JournalCancer Research·DateNov 18, 2005

Scientists discover how to flip a molecular switch

Researchers at Penn State and Rice University discover how to flip molecular switches by engineering their design and surrounding environment. They demonstrated that single-molecule switches can be tailored to respond in predictable ways, depending on the applied electric field direction.

SourcePenn State·JournalJournal of the American Chemical Society·DateNov 18, 2005

APS physics tip sheet #57

A new nanoparticle sensor developed at the University of Rochester can detect individual flu viruses and particles, setting a high bar for detection techniques. Meanwhile, researchers from the University of Twente have found that thin grooves with sharp edges can speed up drying even in humid conditions.

SourceAmerican Physical Society·JournalPhysical Review Letters·DateNov 18, 2005

Loss of fear factor makes timid mouse bold

Researchers found that stathmin is critical for both innate and learned fear in mice. Mice lacking stathmin show reduced fear responses to stimuli, boldly exploring environments where normal mice would hesitate. This discovery advances our understanding of the neural circuitry involved in fear and offers potential therapeutic targets.