Outbreaks linked to unpasteurized orange juice have been on the rise since the mid-1990s. Recent research suggests that this type of orange juice can still carry Salmonella bacteria, highlighting the need for consumers to look for pasteurized options.
A study analyzed data from over 35,975 individuals who underwent colonoscopy without detecting colorectal neoplasia. The results showed a significant decrease in colorectal cancer incidence at 6 months (31%) and persisted for more than 10 years. A negative colonoscopy was associated with a lower risk of developing CRC.
A new project led by Georgia Tech aims to develop strategies to help ports manage seismic risk more effectively. The team will evaluate methods of preventing damage using large-scale tests and investigate applying similar approaches to managing risks from other natural hazards.
Dr. Mary-Claire King has made significant contributions to the understanding of inherited breast cancer, discovering the BRCA1 gene that predisposes individuals to this widespread disease. Her work also explores human genetic diversity and evolution, as well as the application of genomics to human rights problems.
The SAMMS technology can selectively remove metal contaminants without creating hazardous waste or by-products, with initial targets including coal-fired power plants and municipal facilities. In tests, 99.9% of mercury was successfully removed from simulated wastewater, meeting EPA discharge limits.
Research suggests that initiating MS therapy with an immunomodulating drug as soon as possible following a diagnosis can significantly reduce future disease activity and progression of disability. Studies have shown that delaying treatment is associated with more progression of disability and larger volumes of disease damage.
Research using transgenic mice found that lower levels of selenoproteins accelerate prostate cancer development, highlighting the importance of selenium-containing proteins in preventing cancer. Further research is needed to understand how selenium supplements can maximize benefits.
A phase 3 clinical study found that nearly half of patients with advanced illness experienced laxation within four hours of receiving methylnaltrexone, and over 70% responded by the end of the first week. The treatment also showed no diminishment of analgesia due to medication.
A large study of 68,183 middle-aged women found that those who slept 5 hours or less per night were more likely to experience major weight gain and become obese over 16 years. The researchers didn't find a link between sleep duration and physical activity levels.
Researchers found that ACE inhibitor use was associated with a 55% risk reduction for esophageal cancer, a 48% reduced risk of pancreatic cancer, and a 47% reduced risk of colon cancer. The studies suggest that ACE inhibitors may play a valuable role in advancing current treatment options for multiple cancers.
The DOE JGI has completed its 100th microbial genome sequencing, marking a significant achievement in the field of microbiology. This milestone allows researchers to explore and expand their understanding of microorganisms' metabolic profiles and environmental implications.
Researchers at U-M aim to develop new treatments for idiopathic pulmonary fibrosis (IPF) by understanding the role of fibrocytes and signaling pathways involved in the disease. They found that lipid mediators called cysteinyl leukotrienes may be responsible for inappropriate activation of fibrocytes.
A Canadian Blood Services scientist has developed a potential alternative to costly IVIg treatment, which could lead to more effective and safer therapies for patients with life-threatening illnesses. The synthetic product could also reduce production costs and increase availability.
A study of nearly 6,000 dementia patients and their caregivers found that younger, less educated, and more depressed caregivers were associated with higher levels of behavioral symptoms. Understanding the link between caregiver characteristics and patient behaviors may lead to more effective treatment options.
Researchers at Mayo Clinic have found a significant association between acid reflux and esophageal cancer, with patients who experience acid reflux having a 30- to 125-fold increased risk of developing esophageal cancer. The study also discovered susceptibility genes in familial Barrett's esophagus and esophageal cancer.
A study published in Chest Journal found that alcohol abuse increases the risk of pneumonia, with decreased immune system activity being a key factor. The consequences of this study could have a significant impact on a high number of people, particularly in Spain where alcohol is a major cause of death.
Computed Tomographic Colonography (CTC) screening found extra-colonic abnormalities in approximately 16 percent of asymptomatic patients. The most common findings were coronary artery calcifications and non-calcified pulmonary nodules. CTC was also compared to optical colonoscopy (OC) for detecting polyps, with comparable accuracy in i...
A new study provides an explanation for continental plate breakups, showing that they often occur along preexisting lines of weakness created during earlier collisions. The research uses geochemical fingerprinting to demonstrate this principle, shedding light on the history of the Rheic Ocean.
A study found that breast MRI screening can be cost-effective for BRCA1 mutation carriers, particularly when mammography is insensitive. Adding annual MRI from ages 35-54 is cost-effective among all BRCA1 carriers and those with high-risk due to aggressive cancer types
Researchers found that St. John's Wort increased bladder contraction intervals in rats with bladder inflammation, reducing bladder hyperactivity and associated pain. The study suggests that the herbal supplement may be a viable treatment option for women suffering from interstitial cystitis, affecting 700,000 Americans.
Researchers found that men with the same hemoglobin levels before treatment experienced significantly different overall and progression-free survival depending on whether they were black or white. Anemic blacks fare worse than anemic whites, while blacks with high baseline hemoglobin fare better.
Researchers have designed a new quantum processor core that keeps qubits active all the time, enabling faster calculations and making quantum computers more efficient. This breakthrough could lead to advancements in fields like molecular biology, biophysics, and materials science.
Researchers used small interfering RNAs to block the spread of human colorectal cancer cells in laboratory mice, achieving a major reduction in liver cancer growth. The treatment also showed potential for increased cancer cell killing when combined with standard chemotherapeutic agents.
Researchers found Botox injections to improve urinary tract symptoms and quality of life in men with enlarged prostates. The treatment reduced prostate size through apoptosis, improving urine flow and decreasing residual urine.
A novel colonoscope using the NeoGuide System reduces looping and discomfort during colonoscopies, while entonox sedation provides effective pain relief and faster recovery. These advancements increase rates of colorectal cancer screening and improve patient satisfaction.
A new study finds that computer-based screenings increase the odds of identifying domestic violence victims, but don't guarantee that it will be addressed during emergency department encounters. The study found that women are more likely to disclose their domestic violence situations to clinicians who use computer-based screenings, and...
Researchers at the University of Minnesota found a tiny population of cells in the intestine that signal T-cells to fight infections. This discovery may help study and develop treatments for diseases such as ulcerative colitis and Crohn's disease.
A study finds that HIV's impact on severe child malnutrition is limited, and economic growth does not always improve nutrition. The development agenda must tackle child wasting to make a lasting impact on human well-being.
Researchers have developed a 3D modeling technique that shows how antibodies bind to bacterial sugars, allowing for potential new vaccines. This technique can be used to create new vaccines that protect against multiple strains of bacteria.
A new study found that patients with healed erosive esophagitis had better acid control and lower heartburn symptom scores compared to those who did not heal. The study suggests that controlling gastric acid levels is key to healing erosive esophagitis.
Researchers found that aerosolized cyclosporine preserves lung function and reduces chronic rejection in lung transplant patients. The new study used 58 patients and found that those who received the placebo experienced a decline in lung function four times as great as those who inhaled the cyclosporine.
A computer-based screening program increased discussions about domestic violence among women visiting emergency departments, particularly those who received standard care. Women using the computer screening were more likely to disclose their own experiences and receive referrals for domestic violence.
Researchers tracked sperm whales using acoustic recording tags, finding that they produced 'buzzes' to locate cephalopods like squid during deep dives. This non-invasive method provides insight into the timing of prey detection and capture during dives.
Researchers found that women who gained more than 60 pounds during adulthood were almost twice as likely to have ductal type tumors and more than 1.5 times more likely to have lobular type cancers. The risk for metastatic disease increased with weight gain, particularly among those who gained over 60 pounds.
A study of patients over 65 showed that AMITIZA significantly increased spontaneous bowel movements, improving symptoms of chronic idiopathic constipation. The medication was well-tolerated, with fewer adverse events compared to placebo, and is approved for use in adults regardless of age or gender.
A 12-month study showed that NEXIUM maintained normal acid production levels in most patients with Zollinger-Ellison syndrome. Most participants controlled their acid output after just 10 days, and no ulcers or erosive esophagitis were observed at the end of the year.
Researchers have found diverse ecosystems and promising biological samples at newly discovered deep-sea reefs off Miami and Bimini. The team aims to explore these areas to identify factors responsible for their incredible diversity and potentially find new medicines.
Researchers are re-creating submarine channel formation to understand their internal structure and improve oil recovery efficiency. The experiments have yielded counterintuitive results, revealing behaviors that differ from surface rivers due to differences in density.
A new study has found a significant link between lead exposure and long-term brain cell loss and damage. Researchers measured the brains of former employees exposed to lead in their workplaces, finding those with higher levels had smaller brain volumes and more damage.
A study of 85 women with COPD found they had lower lung function, more trouble breathing, and a worse quality of life compared to men. The researchers suggest that comprehensive assessments can lead to improved treatment outcomes for all COPD patients
Researchers found that patients taking ramelteon experienced a significant advancement of dim light melatonin secretion offset compared to placebo. The results suggest that ramelteon may help people adjust to time zone changes and shift their natural circadian rhythm.
A recent study by researchers at Carnegie Mellon University found that lower-income individuals and those with lower levels of education tend to have higher levels of stress hormones in their bodies. This association was independent of other factors such as race, age, or body mass index.
Adults who survived childhood cancer are twice as likely to be unemployed than those without a history of childhood cancer. Those treated for brain or central nervous system tumors face a particularly high risk, while blood-cell and bone marrow cancer survivors experience an elevated but non-significant risk.
Researchers have developed a new integrated system that combines MRI and NIR imaging to quantify hemoglobin, water, and scattering values in breast tissue. This technique may help detect early tumor growth and characterize tumor stage by learning about its vascular and cellular makeup.
A new NIAID study found that a higher dose of flu vaccine significantly increases the immune responses of older adults, providing hope for better protection against seasonal influenza. The trial showed that participants who received a high-dose vaccine had 44-79% higher levels of antibody than those who received the standard dose.
A recent study found that AMITIZA improved symptoms of irritable bowel syndrome with constipation (IBS-C), including abdominal pain and bloating. The treatment was associated with significant improvements in patients' quality of life.
Research links lower physical performance scores to higher risk of dementia, including Alzheimer's disease, in older adults. Those with better physical function tend to have slower cognitive decline and lower risk of developing dementia.
Researchers at MIT have created a new energy system that converts light into electricity, enabling more fuel-efficient cars. The system uses advanced materials and photonics to create intense light, which is then harnessed by photo diodes to power electrical systems.
Researchers found that consuming foods with low glycemic levels and glycemic load can naturally stimulate metabolic response. A study on healthy volunteers also discovered that a low-glycemic-index-breakfast increased levels of the hormone peptide YY, promoting satiety and decreasing food intake.
Physicians will happily adopt information technology, according to Canadian Medical Association Journal commentary. The main barriers to IT adoption are often related to time constraints and resistance from physicians, rather than power or politics.
The Chikungunya outbreak in the Indian Ocean affects several islands and India, with a large portion of populations infected. The disease is caused by the chikungunya virus, spread by mosquito bites, and has no specific treatment. Genetic analysis reveals unique molecular features among outbreak strains.
Researchers have discovered an extensive system of deepwater coral reefs off Miami and Bimini, which are likely to harbor diverse marine life. The newly mapped areas will be explored using submersibles and autonomous underwater vehicles to assess their ecological importance and search for pharmaceutical compounds.
This article emphasizes the importance of addressing social determinants of health inequities. It highlights the limitations of reductionism in medicine and suggests that a systems biology approach could be valuable for clinical medicine, focusing on the holistic characteristics of a problem rather than its component parts.
Researchers have discovered a dichotomy in sea turtle migration patterns in the eastern Atlantic, revealing two distinct foraging strategies. The study found that adult turtles occupy different habitats and diets, with coastal adults being larger and feeding on arthropods, while oceanic adults are smaller and feed on floating plants.
A study published in the Journal of Affective Disorders found that verbal abuse in childhood can lead to increased symptoms of depression and anxiety in adulthood. The researchers studied data from over 5,600 participants aged 15-54 and found a strong correlation between verbal abuse and self-criticism.
Researchers used satellite tracking to follow ten turtles from Cape Verde, discovering they adopted two distinct approaches to finding food linked to their size. This challenge current conservation efforts, highlighting the need for an international cooperative strategy to safeguard these animals.
Researchers found that ancient whales' hind limbs regressed over millions of years via small genetic changes, not a single dramatic event. This discovery highlights the complex process of evolution and developmental biology.
Researchers investigate how changes in tropical vegetation affect carbon emissions and global climate change. They will make measurements in Africa, Australia, and South America to understand the conditions under which rainforests and savannas thrive.
Research at Group Health Research Institute found that participants with higher physical function were three times less likely to develop dementia. Regular exercise may help stave off dementia by improving and maintaining physical conditioning, say researchers.
A new study using ancient climate data reveals a two-way feedback loop where greenhouse gases increase with temperature, accelerating global warming. The research suggests that ignoring this effect could lead to revised estimates of future warming by up to 50%.