A study found that cholesterol accumulation in the liver depletes a powerful antioxidant, making cells susceptible to inflammation and damage. Cholesterol-lowering therapies may offer a useful treatment for nonalcoholic steatohepatitis (NASH) and fatty liver disease.
Researchers at Michigan State University have identified 5,331 unique genes in the human egg, which may hold the key to understanding fertility issues and developing new stem cell therapies. The discovery could also pave the way for the creation of healthy stem cells without the need for fertilized embryos.
A new study shows that trained lay health advisers in rural communities can increase mammography screening rates among low-income and minority women. The intervention improved knowledge and beliefs about mammography screening, empowering women to schedule their own appointments.
Scientists on the NASA African Monsoon Multidisciplinary Analyses (NAMMA) mission used a combination of satellites and aircraft to study hurricanes. They found surprisingly strong winds in tropical disturbances and evidence of dry air, which typically comes from the Sahara Air Layer.
A randomized control group study found that second graders who participated in the 'Healthy Choices, Healthy Me!' program scored 20% higher on food guidance system questions and reported significant increases in selecting healthy foods. The program was also effective in changing behavior over time.
A study found that uninsured Latino children are more likely to have no regular physician and not receive needed medical care due to expense, lack of insurance, or cultural barriers. Parental non-citizenship, low family income, and older child age were associated with being uninsured in Latino children.
Researchers at IRB Barcelona have identified a crucial protein in building the nuclear envelope, a complex structure surrounding the nucleus. The discovery of MEL-28 sheds light on how this envelope is assembled and regulated.
Researchers have found that proteins essential for brain growth during development are equally important for forming long-term memories. Growth factors like BDNF play a critical role in retaining long-term memory by binding to specific receptors in the brain, and their absence can block this process.
A retrospective study by Memorial Sloan-Kettering Cancer Center suggests that radical nephrectomy is a significant risk factor for developing chronic kidney disease. Patients who underwent partial nephrectomy had a lower rate of chronic kidney disease and better kidney function after surgery.
The Braintuning project, a €2.5 million EU-funded research initiative, aims to investigate the relationship between music, emotions, and brain functions. Researchers seek to explain individual differences in musical preferences and emotional responses to music, as well as how environmental factors influence these experiences.
Susanne Wetzel and Rebecca Wright are recognized for their work on a new undergraduate degree program in cybersecurity at Stevens Institute of Technology. The program is designed to provide students with security expertise within a broad education, preparing them for careers in information assurance and computer security.
Postbaccalaureate premedical programs targeting minority and disadvantaged students show effectiveness in increasing medical school admission rates. After participating in these programs, students had a higher probability of enrolling in medical school, with some groups experiencing a 6-fold increase.
Two new breast cancer risk models use breast density to predict individual risks, outperforming the existing Gail model. The models identify high breast density as a significant predictor of breast cancer, with some studies suggesting it may be as powerful a risk factor as age.
A new model developed by scientists from Group Health and seven other health care organizations finds that breast density is a significant predictor of breast cancer risk, with women having highly dense breasts facing nearly four times the risk as those with fat-filled breasts. The study analyzed data from over 1 million women and iden...
Newborns exposed to methamphetamine in utero are 3.5 times more likely to be born underweight compared to those not exposed, with a risk of type 2 diabetes and metabolic syndrome later in life.
A new study found that individuals who become alcohol dependent before age 25 are less likely to seek treatment, experience more frequent and longer-lasting episodes, and meet more dependence diagnostic criteria. Researchers call for increased prevention and treatment efforts for this vulnerable population.
A Mayo Clinic study found that physicians who report making a major error in the previous three months experience burnout and depression, increasing the risk of future errors. The study also discovered a reverse connection, where high burnout levels increase the likelihood of an error in the next three months.
Researchers from ISREC discovered that the Nodal protein, involved in embryonic development, maintains stem cells while also providing cues for their differentiation. This understanding is crucial for coaxing stem cells to grow into specific tissues outside the body and may hold the key to controlling cancerous stem cell behavior.
Researchers studied chimpanzee progression order as they crossed two roads, finding that adult males take up forward and rearward positions depending on risk level and number of adults present. This cooperative behavior helps maximize group protection, suggesting a high level of flexibility in dominant individuals.
Researchers found that human infants and all great apes exhibit identical preferences for remembering where things are hidden. However, this preference shifts in 3-year-old human children, indicating a uniquely human developmental trajectory. The study provides insight into the evolution of human cognitive abilities and tendencies.
A viral target has been found to sustain EBV-related tumors, and blocking its activity breaks the virus life cycle. This discovery could lead to a drug that kills only EBV-positive tumor cells without harming other tissues.
A Hopkins-led study of over 600 people and their families found that siblings, parents, or children of those diagnosed with chronic severe unipolar depression before age 31 have a 2.52-to-1 chance of also having the disorder. This suggests the value of searching for contributory genes.
Researchers found that pied babblers continue to care for their young during this period, using a special "purr" call to recruit inexperienced fledglings. This novel form of extended parental care prolongs offspring care and sheds light on the sophistication of bird parenting.
Antarctica's average temperature has increased by about two-tenths of a degree Celsius, or one-third of a degree Fahrenheit, in the past 150 years. This warming trend is attributed to various factors, including natural phenomena and human-induced climate change.
A study by psychologists at the University of East Anglia found that well-educated parents are more open to designing babies, with differences in desirable traits based on age, sex, and socio-economic class. The research suggests that parents would manipulate their children's physical, psychological, or social characteristics for a per...
A comprehensive mental health study of Hurricane Katrina survivors found that serious mental illness doubled in the months after the hurricane, yet thoughts of suicide did not increase. The study revealed post-traumatic growth, with most respondents experiencing a deeper sense of meaning and greater inner strength.
A study found that medical interns frequently work beyond mandated limits, with rates of injury increasing with extended hours and fatigue. The most common contributing factor to percutaneous injuries was a lapse in concentration, followed by fatigue.
A new compound in the diarylethene family is synthesized and produces a microcrystalline film that becomes super-water-repellent when exposed to UV light, and returns to its original state with visible light. The material's surface undergoes changes in molecular structure, leading to reversible formation of microfibrils.
A new study from the Bradley Hasbro Children's Research Center and Brown Medical School reveals that African American adolescents with depressive symptoms are at a higher risk of engaging in risky sexual behavior. The study concludes that assessing depressive symptoms can help prevent future emotional disorders and HIV/STI transmission...
The Pall eBDS System is a highly sensitive culture-based test that detects bacterial contamination of red blood cells, reducing the risk of sepsis and death from transfusion. The system's novel approach to detection measures oxygen consumption as a marker for bacteria, allowing for effective detection of commonly found contaminants.
A study found that cyclin D1 gene overexpression is associated with better survival outcomes and increased sensitivity to the cancer-fighting drug bortezomib in breast cancer patients. This is because it suppresses the activity of another gene, STAT3, which promotes cell growth and prevents tumor cells from dying.
A new gene signature of 70 genes linked to breast cancer was found to accurately predict patient outcomes, surpassing traditional risk classifiers. The study's results suggest that the 70-gene signature adds valuable prognostic information, which may lead to improved treatment decisions and reduced chemotherapy for eligible patients.
The US FDA has approved a new totally implanted artificial heart, providing hope for patients with severe heart failure. The device is designed for those who are not eligible for a heart transplant and have a short life expectancy without the device.
Advances in biology are hindered by obstacles such as dwindling National Institutes of Health budgets and overly burdensome regulatory requirements. The Association of American Medical Colleges has outlined key recommendations to promote translational research, including increased investment in medical schools and teaching hospitals.
A new study published in PLoS Medicine suggests that delivering rheumatoid arthritis drugs directly into the central nervous system improves treatment outcomes. Researchers found that blocking a protein called p38 with spinal cord administration reduced inflammation, arthritis, and joint destruction in arthritic rats.
Rhesus monkeys display neonatal imitation, reproducing human tongue protrusion and lip smacking after watching experimenters perform similar gestures. The study suggests that imitation may have evolved earlier in the primate tree than previously thought.
A study found that maternal drinking during early pregnancy is linked to a higher risk of alcohol disorders in children, with increased exposure associated with difficulties in thinking, learning, and memory. The study suggests that in utero exposure to alcohol may predispose individuals to early onset of alcohol disorders.
Rising carbon dioxide levels pose unprecedented risks to climate change, as evidenced by an 800,000-year Antarctic ice core record. Human activity has increased CO2 beyond natural ranges, raising concerns about future sinks' effectiveness.
A study by UCSD researchers shows that the central nervous system can sense and modulate inflammation in joints, reducing symptoms of rheumatoid arthritis. Blocking key signaling enzymes in the CNS resulted in decreased joint inflammation and destruction.
The article highlights the alarming rate of chronic diseases and injuries in Latin America and the Caribbean, with seven out of ten deaths attributed to these causes. The authors argue that lack of funding for health research is hindering efforts to address this crisis.
A new study suggests that higher levels of dopamine D2 receptors may provide a protective effect for those most at risk of developing alcoholism. The research found that these receptors, involved in emotional reactions and cognitive control, are elevated in the brains of participants with a family history of alcoholism.
Research supported by NIDA shows that prevention programs in middle school can reduce methamphetamine abuse among rural adolescents. The study found significant effects on both lifetime and past-year methamphetamine abuse, with a relative reduction of 65% compared to controls.
Researchers found a strong decline in lead levels in otters' bones between 1992 and 2004, reflecting reduced emissions from car fuel. The study highlights the importance of long-term monitoring and archiving of samples, providing valuable insights into human health impacts.
A revised dinosaur census by University of Pennsylvania scientist Peter Dodson estimates that 71% of discoverable genera are still awaiting discovery. The researchers predict that new discoveries will decline sharply in the early 22nd century, but a child born today can expect a fruitful career in dinosaur paleontology.
Nearly all U.S. children aged 12-17 years were exposed to tobacco use through movie advertisements televised in 2001-2002. The study analyzed 216 movie trailers, finding that 95% of young people saw at least one trailer with images of tobacco use.
A new study finds that both normal-weight and overweight individuals underestimate calorie content of larger meals. To improve weight loss estimates, consider doubling initial meal size estimates or estimating calories item-by-item. Meanwhile, virgin olive oil rich in polyphenols has been shown to increase 'good' cholesterol levels and...
Researchers argue that emotions, rather than reason, drive public distrust in institutions. The study reveals that concerns about risk are directly linked to lack of knowledge and emotional dread. Building trust requires transparency and reporting back after public consultations.
A US military hospital in Iraq treated 85 children from January 2004 to May 2005, with 56% having traumatic injuries. The experience highlights the need for hospitals near battlefields to prepare for treating civilians, including children.
The article highlights the importance of reliable estimates of global demand for an HIV vaccine in achieving various policy objectives. These objectives include convincing governments and industry to invest more in research and product development, guiding government planning of HIV vaccination programs.
Researchers developed a new, simple, and accurate dipstick test to identify the cause of bacterial meningitis outbreaks in Africa. The test uses patient spinal fluid and can determine the presence of four common meningococcus groups, paving the way for targeted treatment decisions.
Researchers found that anticipation can fire up two brain regions - amygdala and hippocampus - even before the event occurs, strengthening memories of disturbing events. This study has important implications for treating conditions like PTSD and social anxiety.
Scientists found that global warming accelerates springtime flowering, but CO2 and nitrogen deposition have opposing effects on wildflowers and grasses. The overall timing of plant growth is delayed under elevated CO2.
Research suggests that older fathers are more likely to have autistic children, with a significantly increased risk compared to younger fathers. The study, which analyzed data from over 318,000 individuals, found that advancing age among fathers was associated with an increased risk of autism spectrum disorder.
Scientists found that global changes may alter the delicate balance of species coexistence by changing the timing of plant activity. Climate change accelerated springtime flowering of all species, but elevated carbon dioxide and nitrogen deposition caused wildflowers to flower earlier while grasses delayed their blooming.
Researchers found that small-town and rural school-based intervention programs significantly reduced short-term and lifetime methamphetamine use among adolescents. These findings suggest that brief but effective prevention programs can be effective in addressing the growing methamphetamine problem among teens.
Scientists from Newcastle University found a significant increase in extreme rainfall events in Scotland and Northern England over the past 40 years. The probability of such events increased by four times in Scotland and two times in Northern England, posing a major threat to flood risk management.
A new drug has been shown to improve blood flow in diseased arteries by reactivating a damaged enzyme, reducing the risk of high blood pressure and heart attacks. The discovery is a significant development for the treatment of cardiovascular disease and aims to challenge orthodox thinking on heart health.
A study published in Nature Medicine has found that certain non-biological drugs can dramatically reduce tissue inflammation by inducing apoptosis in inflammatory cells. This breakthrough could lead to new treatments for patients with lung and joint diseases, including fibrosing alveolitis and rheumatoid arthritis.
Scientists at EMBL have discovered that beta-catenin plays a central role in determining whether blood cells form or not, and that an overactive Wingless pathway can lead to leukemia and other diseases. The study provides new insights into the processes within cells that lead to cancer.
A study of over 68,000 patients in 44 countries found that Eastern Europeans and Middle Easterners have the highest rates of heart attacks, strokes, and deaths from these conditions. The analysis suggests that cardiovascular disease is no longer exclusive to Western, industrialized world.