Researchers found that the combination of curcumin and PEITC significantly retards prostate cancer tumor growth in laboratory mice. The discovery suggests potential for using plant-based compounds as alternative therapies to treat advanced prostate cancers.
A team of researchers at Duke University has discovered ankyrin repeats, a common protein motif found in humans and other organisms, which exhibit unprecedented elastic properties. The nanometer-sized 'nanosprings' display linear elasticity and can self-repair after repeated stretching.
A double-blind study found that acetazolamide significantly improved patient perception of sleep quality and reduced daytime fatigue in heart failure patients with sleep apnea. The medication showed promise in reducing sleep-related breathing disorders, which may also improve cardiac function.
Researchers at Albert Einstein College of Medicine discovered that chronic suppression of malonyl CoA levels in the brain impairs nutrient-sensing mechanism, leading to increased food intake and obesity. The study suggests a potential new approach to treat obesity by re-adjusting malonyl-CoA levels in the human hypothalamus.
A study examining asthma rates in Hispanics found that Puerto Ricans have the highest prevalence of asthma, with 31% of school children experiencing current wheezing. The study also found significant differences in asthma rates and disease severity among Hispanic subgroups.
Glioblastoma multiforme, the most common adult brain cancer, has a median survival of about one year after diagnosis. Researchers have identified EGFR as a target for therapeutic drugs, offering new hope for patients. The study found that targeting both mutant and normal EGFR can destroy brain cancer cells while sparing healthy ones.
The study found that T cells recognize brain proteins and recruit resident immune cells to fight off toxic substances, enabling neurogenic regions like the hippocampus to form new nerve cells. This process is linked to local immune activity and may play a role in maintaining learning and memory abilities in adulthood.
A four-year study of designer rats with high blood pressure and healthy counterparts has identified candidate genes that may contribute to cardiovascular disease. The online database TREX is now available to researchers worldwide, offering an unprecedented amount of data to mine.
A study of 994 participants from north-east Belgium found a significant association between environmental cadmium exposure and an increased risk of cancer. The study, published in The Lancet Oncology, suggests that higher levels of cadmium in urine are associated with a doubling of overall cancer risk, including lung cancer.
Researchers at OHSU have discovered a protein fragment, p95HER-2, which closely correlates with lymph node metastasis and earlier recurrence of breast cancer. The study suggests that p95HER-2 is a marker for metastasis and may help identify patients with longer disease-free survival.
A study found that high doses of soy isoflavones can block the effects of estrogen in postmenopausal women, potentially reducing breast cancer risk. Women with higher estrogen levels may benefit from a diet rich in soy isoflavones.