A survey of over 2500 men found that almost half who paid for sex had a current partner. Unprotected oral sex was twice as common among those who paid locally, highlighting its role in transmission of STIs.
Behavioral therapies produce reliable changes in bedtime problems and night wakings in infants and children, with 82% of children benefiting from treatment. For women with obstructive sleep apnea (OSA), early diagnosis and treatment can reduce healthcare costs and improve sleep quality.
Researchers found that a defective version of the NPRL2 tumor suppressor gene makes lung cancer cells resistant to cisplatin, a common chemotherapy drug. Gene therapy targeting this gene may restore sensitivity to cisplatin, offering new hope for treating resistant lung cancer.
A new study published in JCSM found that brief behavioral treatment for insomnia (BBTI) significantly improves sleep quality and daytime symptoms of anxiety and depression in older adults. The study showed a 71% favorable response rate among BBTI participants, compared to 39% in the control group.
A population-based study found that people with hand osteoarthritis had significantly shorter white cell telomere lengths compared to those without the disease. Telomere length was also associated with the severity of osteoarthritis, suggesting a link between biological ageing and degenerative inflammatory bone disease.
Researchers found that a specific serotonin receptor regulates brain emotional responses, potentially contributing to depression risk. The study suggests antidepressants may work by shifting this receptor's availability, modulating amygdala reactivity and improving depressed mood.
Scientists at the University of Texas Medical Branch discovered that blocking a single enzyme called aldose reductase can stop colon cancer cell growth. In mouse experiments, tumor progression was completely halted when human colon cancer cells were treated with genetic material that prevented the production of this enzyme.
Researchers at the University of Illinois Chicago have identified an antibiotic that specifically targets the FoxM1 gene, which is responsible for cancer cell proliferation. The antibiotic, siomycin A, was found to induce cancer cells to commit suicide in a process called apoptosis, with no effect on normal cells.
Researchers have successfully cloned mice using fully differentiated blood cells, disproving the need for adult stem cells in the process. The study found that these cells were more efficient than stem cells or progenitor cells, paving the way for new approaches to animal cloning.
A team of astronomers discovered that many large galaxies in the early universe had a low stellar birth rate, suggesting a cosmic 'birth control' mechanism that prevented excessive star formation. The study found that these galaxies formed stars when the universe was just 20% of its current age.
A US survey of obstetricians and gynecologists found that one in three doctors believe free drug samples impact their prescribing choices. More than half of respondents felt it was ethical to accept free samples or lucrative consultancy offers from pharmaceutical companies.