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Science News for December 14, 2007


Aging gracefully requires taking out the trash

Researchers found that boosting autophagy in fruit flies prevented the age-dependent accumulation of cellular damage in neurons and promoted longevity. Boosting autophagy facilitated the removal of damaged molecules that accumulate during cellular aging, which is critical for neurons to stay healthy and functioning.

SourceSalk Institute·JournalAutophagy·DateDec 14, 2007

Cholesterol fine tunes hearing

Researchers at Baylor College of Medicine discovered that cholesterol levels in outer hair cell membranes impact hearing. Depleting cholesterol resulted in hearing loss, while adding it initially increased hearing but later led to a decline.

SourceBaylor College of Medicine·JournalJournal of Biological Chemistry·DateDec 14, 2007

Lymphoma drug used to treat skin disorders

A study published in Dermatologic Therapy reveals that rituximab effectively treats blistering skin diseases, including paraneoplastic pemphigus, by targeting abnormal immune responses. The drug's efficacy is being explored for other serious dermatological disorders, but its indications are still being defined.

SourceBlackwell Publishing Ltd.·JournalDermatologic Therapy·DateDec 14, 2007

Health needs higher for kids of abused moms

A study by Group Health Research Institute found that children of mothers with a history of abuse have higher health care needs, including increased costs for mental health services. The research highlights the importance of screening women for intimate partner violence and providing interventions to minimize its effects on families.

SourceGroup Health Research Institute·JournalPEDIATRICS·DateDec 14, 2007

How molecular muscles help cells divide

Researchers at Yale University discovered how molecular muscles assemble a 'contractile ring' to divide cells, using a 'search, capture, pull and release' mechanism. The mechanism involves protein clusters on the inside of the cell membrane that grow and connect, forming a condensed ring.

SourceYale University·JournalScience·DateDec 14, 2007