A new research study from Oklahoma Medical Research Foundation demonstrates that immunization could blunt or prevent Alzheimer's disease by targeting the build-up of protein plaques. The vaccinated mice showed a significant reduction in plaque accumulation and improved cognitive performance compared to control mice.
Researchers at Thomas Jefferson University have found that the protein IL-27 can block the onset of symptoms in animals with an MS-like disease, suggesting it may be a potential tool for tempering over-active immune responses. Increasing IL-27 concentrations may help quell an over-active immune response and improve symptoms.
Scientists at NIAID identified a key factor contributing to the severity of community-associated methicillin-resistant staph infections. Novel proteins in drug-resistant strains of S. aureus attract and destroy protective white blood cells, ensuring the bacterium survives and causes severe disease.
A systematic review found that the risk of major stroke within a week after a minor stroke is substantial at 5.2%. Studies with emergency treatment in specialist stroke units showed the lowest risks, while population-based studies without urgent treatment had the highest risks.
Researchers have developed a new neural-machine interface that enables prosthetic arms to respond directly to the brain's signals, allowing for greater control and movement. This technology has the potential to provide an even greater number of arm and hand movements beyond the four already achieved.
UT-Houston researchers have identified a defective gene mutation in smooth muscle alpha-actin (ACTA2) that affects vascular smooth-muscle cells, leading to thoracic aortic aneurysms and dissections. The study suggests that contraction of the smooth muscle cells in the aorta is crucial in maintaining its health.
Researchers have identified histone deacetylase HDAC9 as a potential target for treating premature atherosclerosis in lupus patients. They also found that elevated microRNA-16 levels contribute to abnormal cell death in lupus patients, and reducing these levels may lead to targeted treatments.
A study of over 800 children aged 5-12 found that kids treat disloyalty within their group harsher than disloyalty towards outgroups, challenging previous theories of childhood prejudice.