Researchers at Michigan Technological University have developed a powerful tool to pinpoint the genes behind inherited illnesses. By analyzing data from over 1,000 people with and without type 2 diabetes, they identified 11 single nucleotide polymorphisms associated with the disease.
The ExoSeal vascular closure device significantly reduced bleeding time, enabling patients to get up and walk around far sooner than with manual compression. The study found no access site complications at 30 days, a promising result for the safety and effectiveness of the device.
Researchers are developing a global monitoring network for ocean noise to protect endangered species like the North Atlantic right whale. The project uses 3-D buoys to record sounds from whales, fish, ships, and other sources in the Stellwagen Bank National Marine Sanctuary.
A new study published in Sleep confirms that insomnia increases the risk of subsequent depression among young adults. The study, which followed 591 participants over 20 years, found that insomnia was a chronic problem that preceded depression more consistently than vice versa.
The SPOC device, developed at Stevens Institute of Technology, has received FDA 510(k) clearance for its ability to pinpoint specific muscle trigger points causing pain. This innovation has the potential to eliminate ineffective treatments and improve patient outcomes.
A new surgical technique, osteoprogenitor cellular grafting, has been used to treat steroid-induced osteonecrosis of the knee in three young patients. The procedure involves transplanting cellular material from the pelvic area into the knee, resulting in nearly normal activity and knee function with no complications.
A new genetic analysis by Yale School of Medicine researchers suggests that a genetic variant in East Asian populations may have protected residents from becoming alcoholics. The study found that this variant became widespread through natural selection in specific Hmong- and Altaic-speaking groups, hinting at an environmental factor.
A new study found that rap music has shifted from cautionary tales about the dangers of substance abuse to songs that glorify marijuana and other drugs as part of a desirable hip-hop lifestyle. The study, covering nearly two decades, showed a six-fold increase in drug mentions and dramatic jumps in positive framing.
A new study has introduced a nonlethal method to measure the body composition of small rodents using Dual-Energy X-Ray Absorbtiometry (DXA). This technology allows for accurate measurements without harming the animals, facilitating longitudinal research and increasing scientific collaboration between field and laboratory researchers.
The Cedars-Sinai Heart Institute will feature presentations on various topics related to cardiovascular health, including emerging technologies for heart valve repair and women's heart issues. Researchers will also discuss the link between prohormones and cardiovascular disease risk among post-menopausal women.
Researchers found a three-to-four-fold higher overall prevalence of cerebral microbleeds compared to other studies. The presence of cerebral microbleeds is associated with an increased risk of cerebrovascular problems and may reflect underlying cerebrovascular pathology.
A new study by CSIRO scientists warns that climate change will force environmental scientists to rethink their approach to conservation. Temperatures over Australia are projected to rise by about 1 ºC by 2030, and 1.8 ºC by 2070, relative to 1990 levels.
The collaboration aims to promote best practices in sterilization monitoring and provide objective educational resources to customers. Belimed will offer access to 3M's Attest Sterile U Network educational resources, while both companies advance higher standards of practice in sterile processing areas.
Researchers found that people with diabetes have the same high risk for heart attack or stroke as those who've already had a heart attack. The study suggests that all patients with diabetes receiving glucose-lowering treatment are at a particularly high risk of cardiovascular death and disease, regardless of sex and diabetes type.
A new study by Yale and Washington University researchers challenges the idea that complex traits have a 'cost of complexity,' suggesting that many mutations only affect a small number of traits. The team identified genomic regions affecting skeleton characteristics, revealing a well-coordinated process in tuning up complex traits.
A new study has shown that lowering blood pressure in very elderly patients can significantly reduce their risk of death and cardiovascular events. The trial, HYVET, found a 21% reduction in total mortality rate and a 39% reduction in stroke mortality rate among participants.
A large community-based registry of patients treated with drug-eluting stents found that nearly a third of patients stopped taking clopidogrel by one year, but many returned to the medication. Patients who discontinued clopidogrel had a higher risk of death compared to those who continued taking the medication.
A drug-coated balloon coated with paclitaxel has shown to be more effective than a traditional drug-eluting stent in reducing renarrowing of the coronary arteries after six months. The study found lower rates of major cardiac events at one year, making it a promising alternative for treating in-stent restenosis.
Researchers at Harvard have developed gene probe eye drops that enable non-invasive monitoring of brain activity in living organisms. The technology uses MRI to detect tissue repair and has potential applications in treating neurological diseases, diagnosing conditions, and delivering therapeutic agents to the brain.
A new study found no significant difference in mortality rates between patients treated with stenting and bypass surgery for unprotected left main coronary artery disease. However, patients treated with stents were more likely to need repeat procedures to keep the artery open.
A team of scientists discovered cellulose microfibers in ancient salt deposits, estimated to be 253 million years old. This finding suggests that cellulose may have played a role in the development of life on Earth and could potentially serve as a 'paper trail' for searching for life on other planets.
Research found no significant gender gap supporting female candidates, with voters' decisions influenced by the candidate's policies and information rather than their gender. The study suggests women are more likely to support female candidates but evaluated similarly to male candidates based on personal and political considerations.
Researchers have discovered how HIV evades the immune system by altering a key defence mechanism. The Nef protein interferes with the recognition of infected cells, making it difficult for the body to target and eliminate the virus.
A team of Stanford University School of Medicine researchers has developed a new type of imaging system using Raman spectroscopy to illuminate tumors in living subjects. The technique allows for the detection of multiple molecular targets simultaneously, enabling finer biochemical details and more precise imaging.
MRSA cases have increased 10 times in Denmark over the last decade, with community-acquired strains spreading through family and social networks, says Professor Robert Skov. The Danish health system has introduced guidelines to prevent MRSA transmission, but the rising epidemic remains a concern for public health.
Scientists believe that HIV's lack of protection against immune system activation makes it more virulent in humans. Researchers are studying whether artificially disabling this protective function could make SIVs more pathogenic in their natural hosts.
A survey of 50 sex therapists found that satisfactory sexual intercourse typically lasts between 3-7 minutes for men and 7-13 minutes for women. The study aims to dispel unrealistic expectations about the length of sexual activity, promoting counseling over medication for addressing existing sexual problems.
The galaxy proto-cluster LBG-2377 is the farthest ever detected, offering a glimpse into the universe's infancy when its light was emitted. Scientists believe it may grow into a massive galaxy cluster, born from a catastrophic event with gas and matter collapsing.
A nationwide study of 3,000 Lebanese adults found that one in four had a lifetime mental health disorder, with major depression being the most common. Exposure to war-related events significantly increased the risk of developing an anxiety or mood disorder.
Researchers have created a novel nanomachine, called nanoimpeller, that can capture and store anticancer drugs inside tiny pores and release them into cancer cells in response to light. The device has strong implications for cancer treatment and may open a new avenue for drug delivery under external control.
A recent University of Missouri study found that states with repealed universal helmet laws experienced a 12.2% increase in motorcyclist fatalities, while states with universal laws had a 11.1% lower fatality rate.
Regular Tai Chi Chuan exercise improves T cell helper function in patients with type 2 diabetes by increasing T-bet transcription factor and IL-12 production, suggesting a potential therapeutic effect. The study also found improved glycemic control, reduced inflammation, and enhanced immune response.
Researchers found that microRNA miR-200 is a consistent marker of cancer cells expressing E-cadherin but lacking Vimentin. Altering miR-200 levels induced changes consistent with either inducing EMT or the reverse process.
Researchers discovered a pathway plants use to defend against pathogens, involving a signaling cascade that triggers the production of anti-microbial compounds. This understanding could lead to improved crop disease resistance.
Menopause is thought to be an evolutionary adaptation that helps minimize reproductive competition between females in the same family unit. The researchers propose that older women should cease breeding when younger women start to breed, explaining the observed timing of reproductive cessation in humans.
Researchers have identified a master regulator of EMT that consists of a specific group of microRNAs called miR-200. Introducing miR-200 into late cancer cells may provide a new form of treatment by preventing cells from going through EMT and becoming more invasive.
Researchers found that antibiotic treatment doesn't eradicate all Lyme disease-causing bacteria, which may contribute to lingering symptoms. The discovery sets the stage for controlled laboratory research investigating potential therapies for persistent Lyme disease infections.
A team of astronomers from Queen's University Belfast have discovered the nature of five supernova precursor stars using Hubble images. The study reveals that stars with masses as low as seven times the mass of the Sun can explode as supernovae, challenging current understanding of massive star collapse.
A new review of 28,000 patients undergoing joint replacement surgery found that potent anticoagulants may actually lead to more deaths. The authors argue that these drugs have significant side effects and do not prevent pulmonary embolism effectively.
University of Florida chemists develop a new tool to identify biomarkers for serious diseases, potentially leading to earlier detection and improved treatment. The technique uses aptamers to recognize cancer cells and could have applications in disease detection, imaging, and therapy.
Research using virtual reality found that nearly 40% of participants experienced paranoid thoughts, with anxiety and depression also prevalent. The study suggests that paranoia is more common than thought and can be triggered by social interactions.
Researchers have uncovered the molecular mechanism behind chloroform's action as a general anaesthetic, revealing its potential to design new anesthetics with reduced harm. Chloroform inhibits TRPC5 calcium ion channels, a key player in pain transmission and brain function.
Researchers found that ranolazine shortens the QT interval by about 5 percent and improves myocardial relaxation in patients with LQT3 mutation, providing a potential treatment for two conditions. The drug also showed benefits in improving left ventricular relaxation and increasing mitral E-wave velocity.
A team of Canadian and French researchers has identified the TDP-43 gene as a significant cause of ALS (sporadic amyotrophic lateral sclerosis), a neuromuscular disorder affecting motor neurons. The study, published in Nature Genetics, found that up to five percent of ALS patients have genetic mutations in this gene.
Long-term childhood cancer survivors, especially those treated with radiation therapy, experience excess health problems and poor socioeconomic outcomes. The study found that survivors are more likely to have chronic medical conditions, mental health issues, and functional impairment compared to their siblings.
A new study reveals that climate change led to habitat loss in mammoth territory, pushing the species towards extinction. Human hunting acted as the final straw, with scientists estimating that humans would only need to kill one mammoth every three years to push the species to extinction.
A study by SLU cardiologist Melda Dolan found that ultrasound contrast agents are safe and beneficial for diagnosing life-threatening heart disease. The researchers examined nearly 24,000 patients who received contrast agents during echocardiograms and compared their results to those of approximately 6,000 patients without the agents.
Researchers at Purdue University have developed a proof-of-concept active-matrix display using transparent transistors and circuits. The display utilizes organic light-emitting diodes (OLEDS) with nanowires, which rival the brightness of conventional pixels in flat-panel television sets.
A majority of US physicians now support national health insurance, with significant increases in support across medical specialties. The survey found that nearly every specialty showed an increase in levels of support for national health insurance, with some specialties like psychiatry and emergency medicine seeing major increases.
The IN-CAM Outcomes Database aims to address gaps in CAM research by providing outcome measures and a forum for information exchange among researchers. This innovative initiative promises to lead to more effective treatments in the future.
Scientists warn of an impending crisis due to superbugs like Acinetobacter that have become resistant to all available antibiotics, including those thought safe. The bacteria cause severe infections, pneumonia, skin, and wound infections, and even meningitis, leading to significant patient mortality.
A clinical trial using IVUS technology found that Actos reduced the atherosclerotic burden in coronary arteries compared to glimepiride, and prevented progression. The study adds to the body of cardiovascular data for Actos, showing no evidence of increased risk of heart attack or stroke.
Researchers have modeled flameless combustion in a gas turbine engine, finding reduced NOx emissions with almost uniform heat release. This process could lead to more efficient power generation and lower polluting emissions.
The USC project, led by Gully A.P.C. Burns, aims to develop software for laboratory use, creating a small-scale knowledge base for storing scientific articles locally. The project seeks to alleviate information overload and enable researchers to quickly find and retrieve data.
Researchers at UC San Diego have created a method to determine the structure of nonribosomal peptides in just one day, compared to six months or a year previously. This breakthrough may aid in the development of new drugs inspired by natural compounds with antibiotic and antiviral properties.
A recent study published in the Journal of Periodontology suggests that periodontal disease can impact how people smile and display positive emotions. Researchers found correlations between gum disease and reduced smiling width, more mouth covering, and lower perceived quality of life.
A new study from Northwestern University finds that positive feedback can actually escalate perceived threats to the ego and increase the need to prove a questionable decision was right. Research participants who received praise for skills unrelated to the decision were less likely to recommit to it.
Scientists have discovered that microbes produce dimethyl sulphide (DMS) gas at a rate of over 200 million tonnes per year in the world's seas. This climate-changing gas has multiple effects, including triggering cloud formation and attracting birds to food sources.
A new medication, pimecrolimus, failed to reduce arterial renarrowing after stenting, while a multi-reservoir stent design with the drug delivered better outcomes. The study used a combination of pimecrolimus and paclitaxel for comparison.
The study found that the Excel stent is associated with a low incidence of cardiovascular complications, and six months of dual-antiplatelet therapy appears to be feasible and safe. The results showed an overall rate of major cardiovascular complications of 2.77%, including cardiac death, heart attack, and repeat coronary procedure.