Children from poor areas are four times more likely to sustain serious injuries while walking or cycling compared to their affluent peers. Serious injury rates vary by settlement type and location, highlighting persistent inequalities.
Research published in BMC Neuroscience found that physical activity from juvenile age delays the onset of specific motor deficits in a mouse model of Huntington's disease. The study suggests that benefits stem from stimulation of neuronal receptors and other molecules that prolong normal function and delay motor deficits.
A randomized trial published in PLoS Medicine found no differences in cognitive decline between patients who continued and those who discontinued neuroleptic drugs. The study also found that patients with severe neuropsychiatric problems may have benefited from continued therapy, but this effect was not statistically significant.
Researchers found two star systems with yellow supergiant eclipsing binary characteristics, which may be the progenitors of rare supernovae. The discovery was made using the Large Binocular Telescope and suggests that these systems could explain the unusual nature of certain supernovae.
A veterinary neurologist is studying gliomas in dogs and people to develop more precisely targeted treatments. Researchers are using canine models to identify molecular similarities between human and animal gliomas.
A new study shows that a combination of two drugs can lower blood pressure and reduce cardiovascular risk by 20%, outperforming an ACE-diuretic combination. The therapy has the potential to improve control rates to over 80% and alter current guidelines for treating high blood pressure.
The Interactive Autism Network (IAN) has facilitated connections between parents and researchers, providing valuable data on causes, treatments, and potential cures for autism. The registry has revealed significant insights, including maternal depression and ineffective treatments.
Researchers at the University of Leicester have discovered that TB bacteria accumulate body fat to aid survival during transmission, increasing resistance to anti-TB drugs. This finding challenges established views on bacterial transmission and offers new insights into developing targeted treatments.
The XIENCE V everolimus-eluting stent demonstrated better clinical outcomes compared to the Taxus paclitaxel-eluting stent at two years, with a 40% lower overall MACE rate. The study found significant reductions in repeat procedures and heart attacks, but no difference in blood clotting rates.
Researchers develop materials impregnated with bacteria-killing viruses to prevent MRSA infection spread in hospitals. The technique allows the viruses to stay active for over 3 weeks, killing bacteria on surfaces and in wounds.
Research highlights the risks of cervical cancer in women with abnormal HPV test results, regardless of Pap test status. Additionally, a study finds that smoking is an addiction that should be treated like chronic diseases and that health insurance should reimburse for long-term nicotine replacement therapy.
Researchers aim to create bespoke soils with added calcium silicates to capture carbon dioxide and form harmless mineral calcium carbonate. This could contribute 5-10% of the UK's carbon reduction targets in the future.
Infections caused by PVL-Staphylococcus aureus can lead to necrotising haemorrhagic pneumonia with high mortality rates. The UK has seen an increase in PVL-related disease, with around 2% of Staphylococcus aureus strains producing the toxin.
Research suggests that transference is more pronounced when an individual's energy resources are low, rather than abundant. Studies have shown that people tend to rely on automatic associations and fail to notice differences when they are tired or at a circadian mismatch.
A recent study found that obese adolescents burn fat at lower intensities than their lean counterparts during exercise. The researchers identified the optimal intensity levels required to maximize fat oxidation in both groups, with the lean boys reaching a higher VO2 peak and burning more fat at higher intensities.
Birds select fruit with high antioxidant concentrations, boosting their immune systems. Researchers found that blackcaps preferred foods containing flavonoids, even when they appeared darker.
Jim Hutchison, a chemist and materials scientist at UO, emphasizes the need for interdisciplinary teams to address nanomaterial safety concerns. He advocates for green chemistry approaches to reduce byproducts and simplify purification, accelerating data collection on material hazards.
A study examining suicide rates among ethnic groups in England found that young black men aged 13-24 were at highest risk. The research suggests symptoms commonly associated with suicide vary across ethnic groups, making it harder to predict suicidal behavior.
A global study found that telmisartan is as effective as ramipril in reducing cardiovascular death, with fewer side effects such as coughing and swelling. The medication offers clinicians and patients a better alternative for managing high blood pressure.
A new study suggests that taking pioglitazone can help slow the progression of plaque build-up in coronary arteries, which is particularly aggressive in patients with diabetes. The findings have important implications for managing patients with type 2 diabetes and coronary artery disease.
Researchers at USC have found that fasting for two days protects healthy cells from chemotherapy, while leaving cancer cells vulnerable. This discovery holds promise for developing more selective and less toxic chemotherapy treatments.
Researchers found that women with Caesarean deliveries for their first child have lower fertility rates in subsequent pregnancies compared to those giving birth vaginally. The study of nearly 600,000 births shows a 12% reduction in the number of children born after a first C-section.
Researchers have successfully tested Ebola vaccines in primates, triggering a cell-mediated response and producing effective protection. The candidates are now set to be tested on humans for the first time, offering hope for controlling outbreaks and protecting healthcare workers.
A collaborative effort by over 90 researchers from 40 centres analysed genetic data from 70,000 people to identify differences in the genetic code that make some individuals more susceptible to type 2 diabetes. The study found six new genes contributing to the risk, bringing the total to sixteen, and provides valuable insights into the...
A team of researchers from MIT and CNRS studied the phenomenon of triangular tears in adhesives like tape and plastic sheets. They found that these tears arise from interactions between three properties: elasticity, adhesive energy, and fracture energy. The study has potential industrial applications in microtechnologies.
Egyptian scientists have discovered that green tea boosts the effectiveness of antibiotics against superbugs by up to 99.99%, increasing the killing power of chloramphenicol and making 20% of drug-resistant bacteria susceptible to cephalosporin antibiotics.
A study published in JAMA found that high-dose tirofiban had similar outcomes to abciximab in reducing ST-segment elevation after angioplasty. Additionally, sirolimus-releasing stents reduced major adverse cardiac events by half compared to uncoated stents.
A new microarray chip can detect up to 300 different viruses infecting farm animals, birds, and insects. The chip has already been successfully used to identify a coronavirus and foot-and-mouth disease virus.
A team of researchers has discovered six new genetic variants associated with an increased risk of type 2 diabetes, bringing the total number of genetic risk factors to 16. The study used combined genetic data from over 70,000 people and provides new clues to the processes that go wrong when diabetes develops.
Nitrous oxide emissions from waste treatment plants and agriculture are increasing at alarming rates, posing a significant global warming threat. The release of this potent gas can be controlled with suitable management strategies, but recognition of its importance is crucial.
Scientists at the University of Michigan have identified six new genes that play a role in type 2 diabetes, including one also linked to prostate cancer. The study provides insights into the mechanisms controlling glucose levels in the blood, offering potential new methods for preventing or treating the disease.
Scientists at HMI and University of Applied Sciences in Berlin have successfully visualized three-dimensional images of magnetic fields inside solid, non-transparent materials. By detecting changes in neutron spin rotation, the researchers can reconstruct a three-dimensional image of the magnetic field distribution within the sample.
A standard sampling regime is being developed to identify superbug genes in intensive care unit environments. The technique uses polymerase chain reaction (PCR) to characterise micro-organism genes and spot antibiotic resistance, allowing for the detection of MRSA and other drug-resistant bacteria.
Researchers at Penn's School of Medicine present innovative discoveries on a new drug therapy that may prevent heart attacks and strokes. Additionally, studies reveal significant disparities in the treatment of women with atrial fibrillation, highlighting the need for more referrals to ablation therapy.
Researchers have identified neurons that form different spiral-shaped axons on the left and right sides of the brain, suggesting a possible explanation for brain asymmetry. The findings provide new insights into how the brain processes information and could lead to a better understanding of cognitive performance and social behavior.
A Phase III study found that high-dose tirofiban was non-inferior to abciximab in reducing ST-segment elevation in STEMI patients. Tirofiban also showed improved safety profiles with lower thrombocytopenia rates compared to abciximab.
A recent study from Temple University's School of Medicine found that regular communication with doctors can significantly lower the risk of cardiovascular disease. By using an internet-based health reporting system and regular clinic visits, participants were able to improve their blood pressure, blood lipid levels, and cardiovascular...
A recent poll in Edinburgh revealed that 87% of respondents were unaware of smallpox's extinction, a disease that killed 300-500 million victims in the 20th century. However, many people showed knowledge of microbes' role in medicine, volcanoes, and other areas.
A new study found that intensive antiplatelet therapy with prasugrel reduces ischemic events, including stent thrombosis, compared to standard clopidogrel. The treatment shows promise for patients undergoing percutaneous coronary intervention.
Researchers from NewYork-Presbyterian Hospital/Columbia University Medical Center presented findings on the effectiveness of drug-eluting stents in preventing restenosis. The studies also explored the safety and efficacy of bivalirudin for patients undergoing primary angioplasty, particularly those with diabetes and advanced age.
Researchers at Yale University found that exposure to DES alters HOXA10 gene expression, leading to uterine cancer and fertility problems in female offspring. Long-term effects of similar substances like BPA on reproductive health remain a concern.
The adolescent brain experiences increased connectivity and integrative processing, with gray matter peaking in childhood and declining thereafter. These changes enable increased executive functioning, novelty seeking, and risk-taking behaviors during adolescence.
A team of researchers has developed a unified theory of lightning discharges, explaining how different types of lightning form. The study reveals that blue jets and bolts from the blue are triggered by specific charge imbalances in clouds, with the height of the cloud influencing their formation.
Dr. Savitsky has been recognized for his significant contributions to high-speed vessel design through his research and papers. His pioneering work on hydrodynamic design methodology is still widely used today.
The Penn State project will focus on gaining a better understanding of factors related to aggressive behavior and social-emotional competence in children when they first enter school. Researchers will develop and evaluate a multi-component prevention program to support healthy social and academic development.
A new method identified rare gene mutations in people with schizophrenia, which disrupt genes in pathways of neuronal development and regulation. The study suggests a previously unknown role for rare mutations in the causation of schizophrenia.
The Boston College lab's proprietary PyroBayes software can analyze half a million DNA sequences in 10 minutes, significantly improving computational speed and accuracy. This technology has the potential to decode individual genomes at a lower cost, enabling researchers to study genetic causes of diseases and traits in animals.
A study of 27 children with periodic fever, aphthous ulcers, pharyngitis and adenitis (PFAFA) found that tonsillectomy was nearly always effective in resolving symptoms. Despite no clear explanation for why the surgery works, doctors are optimistic about its potential to improve treatment outcomes.
A study of 42 amateur boxers found microhemorrhages in three cases, a potential precursor to Parkinson's disease and dementia. However, the differences were not statistically significant, leaving conclusive statements unclear. Further research on professional boxers is planned to assess intensive exposure to blows.
Researchers have developed a technique to arrange individual carbon nanotubes into circuit patterns with high accuracy. Meanwhile, superconductors can harness quantum physics to boost computer power, potentially creating more powerful qubits for quantum computers.
Computer simulations revealed that pachycephalosaur domes enabled safe collisions during courtship combat, allowing nearly-adult dinosaurs to handle head-butting contests. The study suggests special sliding joints in the vertebrae and giant domes played key roles in this ability.
Epilepsy patients face challenges in communicating with healthcare professionals about medication-related side effects. Advocates propose strategies to improve patient-physician communication and individualized treatment plans.
A recent study published in The American Journal of Medicine found that decreased sexual satisfaction in postmenopausal women is not clearly associated with cardiovascular disease. However, dissatisfaction was linked to peripheral arterial disease and angina, while sexual satisfaction was inversely related to these conditions.
A study by Dana-Farber Cancer Institute found that expanded palliative care services improve communication between families and caregivers, symptom management, and quality of life for children dying from cancer. The study also revealed a shift in where children are dying, with more dying at home or in hospice care.
A consensus statement by ADA and ACC recognizes NMR measurement of LDL particle number as a more accurate assessment of cardiometabolic risk. This method appears to be more closely associated with cardiovascular disease risk than traditional LDL and non-HDL cholesterol measures.
Research at Yale University reveals a link between grhelin, the hunger hormone, and decreased fertility. Grhelin's impact on reproductive health is seen in mice bred with low ghrelin levels, producing smaller litter sizes and altered uterine development.
Researchers at Temple University found a correlation between CD163+/CD16+ monocyte subsets and viral load in HIV patients. This subset increase may serve as an early indicator of immune impairment and disease progression.
Researchers have successfully fired photons back and forth between a space satellite and a ground-based station, demonstrating the possibility of a secure quantum communication channel. The achievement marks an important step towards global communication via satellites using quantum mechanics.
A new study from Boston Children's Hospital found that digital music players like iPods do not affect pacemaker function. However, the devices can interfere with telemetry, requiring a minimum distance of six inches to avoid issues.
Researchers identify collagenase-2 as a key player in multiple sclerosis development, providing a potential new therapeutic target. The enzyme's role in degrading tissue and allowing unwanted cells to invade the brain may be effectively blocked by pharmaceutical intervention.