Researchers at UT Southwestern Medical Center discovered that FGF21 blocks the effects of growth hormone, potentially extending life span. The study found genetically altered mice with resistance to growth hormone produced greater amounts of growth hormone.
A recent animal study found that inadequate sleep in elderly mice exacerbated cellular aging, leading to increased misfolded proteins and cell death. The unfolded protein response was impaired in old mice, failing to properly handle protein synthesis in the endoplasmic reticulum.
A 50-year analysis of Narragansett Bay fish-trawl surveys reveals a shift from vertebrate to invertebrate species and from benthic to pelagic species composition. The study attributes this change primarily to global warming, with smaller, warm-water species increasing while larger, cool-water species declining.
A study showed that Caphosol use led to lower OM rates and severity, as well as low pain medication use and high patient satisfaction among cancer patients. High efficacy ratings were also reported by physicians.
Recent research suggests that almonds contain prebiotics that can stimulate the growth of beneficial gut bacteria, supporting overall digestive health. The study found that finely ground almonds significantly increased levels of certain beneficial gut bacteria, with this effect being attributed to the presence of almond lipids.
Researchers at McGill University have discovered a compound called silvestrol that can re-sensitize tumors to chemotherapy, making them susceptible to anticancer drugs. Silvestrol, derived from Malaysian folk medicine, has been shown to effectively reduce resistance to chemotherapy agents used to treat cancer.
The High-Resolution Soft X-Ray Spectrometer (SXS) will investigate dark matter, galaxy formation, and explore the nature of matter in extreme environments. NASA's Explorer Program Mission of Opportunity has awarded $44 million for the instrument and operations.
Researchers have designed a new probe to image thousands of protein interactions inside living cells, giving them a tool to untangle signaling pathways. The probes are derived from an enzyme and its peptide substrate, allowing for easy detection of protein interactions.
The study reveals that three RAMOSA genes (RA1-3) control maize inflorescence branching, leading to changes in grain yield. The genes regulate the architecture of maize ears through a complex network, influencing plant development and adaptation.
Scientists at the University of Bristol developed an intelligent, visual surveillance system to track African penguins' population dynamics and social behavior. The 'Penguin Recognition Project' uses unique biometric identifiers to monitor large numbers of species cheaply and automatically.
Researchers at the University of Missouri have discovered that submerged oak trees can store carbon for up to 14,000 years, significantly longer than trees in forests. This process reveals the importance of proper tree disposal and benefits of riparian forests in reducing greenhouse gas emissions.
The INFORMS Society for Marketing Science has announced the inaugural 10 recipients of its Fellow Award, recognizing their significant contributions to the development of knowledge and practice in marketing. The honored researchers include prominent figures such as Frank Bass, John Hauser, Gary Lilien, and Richard Staelin.
Research suggests that enhancing neprilysin production can reduce plaque formation and neuron death associated with Alzheimer's disease, but at the cost of shortening lifespan. Over-activation of neprilysin also reduces CREB protein activity and increases age-dependent axon pathology.
A team of scientists has used paleobotanical evidence, genetic analysis, and microbotanical techniques to reconstruct the early history of maize agriculture. They suggest that maize may have been domesticated in Mexico around 10,000 years ago, based on findings from sediments at San Andrés, Tabasco.
Researchers at the Uniformed Services University of the Health Sciences have been awarded a $5.6 million grant to develop vaccines and treatments for Nipah and Hendra viruses. The grant will support collaboration with Australian researchers to test vaccines and therapeutics, which have shown promising results in previous studies.
Paramutations, a process where one copy of a gene can alter the expression of another, have been found in plants and may be important for introducing changes under environmental stress. Researchers studying paramutations in maize identified genes and mechanisms involved in this epigenetic process.
A team of Brown University researchers has invented mercury-absorbent materials to capture mercury vapor from broken compact fluorescent lamps (CFLs). The technology can be applied to packaging and plastic bags, making it an inexpensive solution to mitigate environmental concerns and health risks.
Researchers at UC Davis have isolated and expressed a pheromone-degrading enzyme in the Japanese beetle, which could lead to more effective pest control methods. By degrading pheromones, males may be unable to detect females and reproduce.