Using a systems biology approach, researchers identified that the master gene controlling the biological clock is sensitive to nutrient status in Arabidopsis. The study provides evidence that plant nutrition affects circadian functions, linking nutrient regulation to biological clock control.
A research team led by Mark Hoddle has successfully used biological control to eradicate the glassy-winged sharpshooter, a major agricultural pest, from Tahiti and neighboring islands. The team introduced a microscopic parasitic wasp that attacks the insect's eggs, reducing its population to less than 5% of its original density.
Researchers found that bile acid derivatives can activate the vitamin D receptor without causing calcium buildup, suggesting a new therapeutic direction. Additionally, overexpressing lipoprotein lipase in mice improved their tolerance to cold temperatures by increasing muscular thermogenesis.
A study found two gene variants in the AKAP protein family to be linked to an elevated breast cancer risk, particularly in women from breast cancer families. These variants, located on the AKAP9 gene, were found to increase the risk by 17% and 27% respectively.
Researchers at Karolinska Institutet have discovered a network of genes that lower blood cholesterol levels and prevent the development of atherosclerotic plaques. The findings suggest that targeting these genes could be an effective way to combat atherosclerosis, the main cause of myocardial infarction and stroke.
Researchers Daniel J. Madden and Lee W. Jacobi have found an infinite number of solutions to Euler's Equation of degree four, a centuries-old mathematical puzzle. They used elliptic curves to generate new solutions, which are more efficient than previous methods.
Women with breast cancer who are obese experience more aggressive disease, including higher rates of inflammatory breast cancer and increased risk of recurrence. Obesity can lead to weight gain during treatment, further increasing the risk of recurrence.
The Swiss Systems Biology Initiative has announced eight Flagship Projects involving 79 research groups from 11 universities and institutions. The projects focus on basic biological questions, including lipid roles in cells and decision-making mechanisms in the brain. Funding for these initiatives will be at least CHF90 million.
Research reveals that microRNA depletion is necessary for tissue regeneration and that manipulating certain microRNA levels can enhance regenerative success in zebrafish. By tweaking the FGF signaling pathway, scientists were able to increase or decrease specific microRNA levels, resulting in improved or inhibited fin regeneration.
A study published in the American Journal of Geriatric Cardiology found that established ECG norms for older adults may need to be revised. The research team analyzed over 700 patient readings and discovered that average cutoffs for measuring ECG intervals were greater than current norms, particularly in men.
Tests on ground squirrels found that moderate cortisol levels improve learning, while low or high levels impede it. The study suggests a link between cortisol and learning, which could inform understanding of human cognitive development.
A team of scientists identified the TEX11 gene on the X chromosome as a key player in meiosis and male infertility. Disruption of this gene causes sterility in males and reduces female fecundity, highlighting the importance of sex chromosomes in fertility.
A study by the American Heart Association found that minority and financially vulnerable adults with insulin-treated diabetes are less likely to monitor their blood glucose levels. The disparities were greatest for low-income Hispanics, with significantly lower rates of daily self-monitoring compared to whites.
Workers exposed to low levels of an asbestos-like mineral from Montana vermiculite are at increased risk for lung disease today. A 25-year follow-up study found that even low cumulative exposure can cause changes in the lining around the lungs.
Biologists at Duke University Medical Center have discovered microRNAs that control the regeneration of zebrafish fins. The study found that reducing levels of one microRNA, miR-133, speeds up fin regrowth, while increasing it slows it down. This discovery could lead to new ways to stimulate human tissue regeneration.
Researchers developed a bioinformatics technology that analyzed more than 14 million microbial and viral sequences, revealing distinctive metabolic profiles among viral metagenomes. This discovery has the potential to answer questions about viral dynamics in diseases like cystic fibrosis.
Researchers develop algorithm to analyze financial data and predict company failure, outperforming single-approach methods. The hybrid approach uses genetic-based weighting to identify fittest variables, allowing for accurate predictions of financial future.
The Office of Naval Research selected 27 proposals for funding based on merit review. Young Investigator Awards provide up to $100,000/year for three years to support research and teaching careers.
Researchers found that proteins BMP2, BMP4 and BMP7 inhibit medulloblastoma tumor growth while inducing malignant cells to develop into normal neurons, offering a potential new treatment for the cancer.
Researchers found that surgery combined with heated Intraperitoneal Hyperthermic Chemotherapy (IPHC) improves survival rates for patients with peritoneal carcinoma originating from colorectal or appendix cancer. The study also showed that IPHC may have some benefit in select patients with peritoneal carcinoma and hepatic metastases.
The Human Proteinpedia portal integrates and shares human protein sequence data, facilitating comparisons and interpretations. It offers a standardized view of the proteome, allowing registered users to deposit, retrieve, and share validated data.
A meta-analysis conducted at the University of Kentucky found Transcendental Meditation to be an effective treatment for controlling high blood pressure, with significant reductions in systolic and diastolic blood pressure.
Sea turtles are blocked by lost logs along Gabon's beaches, impeding nesting attempts and killing some female turtles. Logging practices pose a significant threat to critically endangered leatherback turtles.
A study of workers exposed to Libby vermiculite found high prevalence of scarring and thickening of the chest wall membrane 25 years after exposure. Even low levels of exposure were associated with significant health risks.
A UC San Diego researcher has identified a new enzyme target that can reduce the production of beta-amyloid peptides, a hallmark of Alzheimer's disease. By inhibiting this enzyme, the researchers observed improved memory and reduced levels of beta-amyloid protein in mice bred to exhibit Alzheimer's disease symptoms.
Children who gain weight rapidly after tonsil surgery may experience relapse or worsening of snoring, according to new research. African-American children are more likely to relapse, highlighting the need for long-term follow-up and monitoring of BMI gain.
Adolescent girls with ADHD are more likely to develop body-image dissatisfaction and binge-eating behaviors, according to a new study. The study found that these girls may be at risk for eating disorders, depression, and anxiety due to impulsive behaviors.
Researchers at Columbia University Medical Center have identified a process in the brain that may link Alzheimer's disease to stroke. A peptide called p25 is believed to cause an increase in amyloid beta production, which is linked to Alzheimer's.
Researchers have developed a method using near-infrared light to identify microscopic changes in brain tissue associated with Alzheimer's disease. This technique can potentially detect the disease earlier than current methods, which rely on clinical symptoms or imaging tests.
The Scripps Research Institute has been awarded a $4M grant to study the effects of chronic marijuana use on cognitive function, withdrawal symptoms, and stress systems. The research center aims to develop effective treatments for marijuana addiction by pooling expertise in tissue analysis, imaging, animal models, and human clinical tr...