Research analyzed over 100,000 patients with stage IV non-small cell lung cancer and found a modest but statistically significant improvement in one-year and two-year overall survival rates from 13.2% to 19.4% and 4.5% to 7.8%, respectively.
A new review article highlights the importance of detailed diagnosis for talus fractures, which are commonly misdiagnosed due to complex anatomy and subtle radiographic clues. By recognizing these injuries and providing targeted treatment, patients can avoid permanent disability and improve outcomes.
Researchers at Ohio State University have developed a tumor-attacking virus that kills brain-tumor cells and blocks the growth of new tumor blood vessels. The virus, called RAMBO, was tested in animal models and showed promise in treating aggressive brain cancer with a survival rate of 54 days.
Mid-infrared laser breakthroughs to 120 watts, boosting infrared countermeasures for aircraft protection. Researchers developed QCL devices resistant to filamentation, increasing peak output power and ridge width.
Researchers found that a prolonged exposure to TGF-ß1 causes cancer cells to become even more aggressive and likely to spread. A potential treatment, nutlin3, blocks the cancer-causing effects of long-term TGF-ß1 exposure, preventing metastasis and killing cancer cells.
The Chang'E-1 orbiter has provided significant insights into the moon's surface topography, gravity fields, and interior structures. Researchers have discovered impact basins, volcanic deposit highlands, and a massive mascon in the South Pole-Aitken basin.
A new study by Northwestern University found that ethnic pride is crucial for the mental well-being of young African-American adolescents. The research discovered that increased feelings of ethnic pride are associated with reduced depressive symptoms in both male and female students.
A study found that patients with a specific gene variant are twice as likely to develop congestive heart failure, suggesting a genetic link between vitamin D action and heart disease. The research analyzed the genetic profiles of 617 subjects and identified a critical enzyme associated with the development of congestive heart failure.
New live cell imaging techniques allow researchers to visualize dynamic changes in living cells, providing insights into biological processes. The application of computational image processing is also crucial for extracting meaningful data from this type of imaging.
Researchers found that mice deficient in a gene required for autophagy develop muscle atrophy and weakening, resembling certain diseases. Maintaining normal autophagy levels is crucial to clear away damaged cells and prevent muscle weakness with age.
Researchers found that gestational glucose intolerance during pregnancy predicts an increased likelihood of metabolic syndrome at 3 months postpartum. This study suggests women with this condition may be at high risk for future cardiovascular disease.
Despite increased availability of prescription antiplatelet medications, the overall use of blood-thinning agents among stroke survivors has plateaued. Aspirin remains the predominant agent used for secondary stroke prevention, with no improvements in antithrombotic agent usage over a 7-year period.
Researchers at North Carolina State University have created a new breed of antennas that can be bent, stretched, cut and twisted without breaking. These shape-shifting antennas use an alloy that remains liquid at room temperature, allowing them to retain their mechanical properties and tune into different frequencies by stretching.
A study found that patients with peripheral arterial disease (PAD) and no symptoms of heart disease are at high risk for cardiovascular events. Asymptomatic coronary artery disease was detected in 24% of PAD patients through non-invasive imaging, highlighting the need for extensive cardiovascular risk factor management.
A study by Dr. John Garry and Dr. Maria Lohan found that young men who perceive declining happiness with age are more likely to engage in risky health behaviors like binge drinking. The researchers analyzed data from over 1,000 citizens of Northern Ireland aged 15+, finding that just over half were categorized as binge drinkers.
A study found that insulin resistance in adolescents with type 1 diabetes affects heart and vessel function, as well as exercise capacity. The research suggests that addressing insulin resistance early on may help decrease cardiovascular morbidity and mortality in this population.
A new study by University of Missouri researchers found that well-informed citizens are less swayed by White House rhetoric, while the general public is more susceptible to manipulation. Simple and compelling language used by presidents can significantly increase public support for military actions overseas.
Research by Professor Yasuhiko Minokoshi and Dr. Tetsuya Shiuchi found that meals with sweet taste stimulation activate 'orexin' neurons, reducing blood glucose levels in mice. Pleasant eating habits may prevent hyperglycemia by activating orexin neurons.
Researchers found that healthy behaviors such as eating more fruits and vegetables, exercising regularly, and self-weighing were associated with successful weight loss. Unhealthy weight control behaviors, including laxatives and fasting, were not linked to weight loss in adolescents.
Marine aquaculture has the potential to meet global food demand as freshwater resources are limited and terrestrial agriculture struggles. Expanding marine aquaculture operations using low-on-the-food-chain organisms like plankton and algae can achieve sustainable growth.
A study using fMRI revealed that adults exposed to lead as children incur permanent brain injury, with distinct areas of the brain affected differently. Lead exposure has been associated with diminished IQ, poor academic performance, and increased risk of criminal behavior.
A recent study found that more than 1,013 US patients are admitted to hospitals each year with aviation-related injuries, including lower limb fractures as a common injury among passengers and parachutists. The study highlights the need for improved aircraft design to prevent these injuries.
A new study published in the Journal of the American Dietetic Association found that adolescents who successfully lost weight reported using six or more healthy weight control behaviors, such as eating more fruits and vegetables and exercising regularly. In contrast, those who did not lose weight relied less on structured behavior stra...
Researchers found that 71% of participants reported dreamlike mental content associated with sleepwalking or sleep terrors, often involving unpleasant emotions like fear or terror. The study also suggests that adults with these sleep disorders may be acting out dreamlike thoughts during episodes.
NASA's CloudSat satellite noticed a drop in Typhoon Nida's cloud tops from over 9 miles high to around 8 miles high, indicating less powerful thunderstorms and weakening winds. The storm has zigzagged between 18 and 20 degrees North Latitude, moving west, then east, and now back in a westward direction.
Researchers at Helmholtz Munich have discovered a new source of nerve cell generation in the adult brain, specifically in the olfactory bulb. This discovery may lead to new therapeutic approaches for Alzheimer's disease, where nerve cell degeneration plays a crucial role.
A U.S. Geological Survey scientist is using a satellite collar on a North Pole wolf named Brutus to learn about the Arctic wolves' behavior in winter. The collar collects and stores locations every day, which are then emailed to researchers, allowing them to track the wolf's movements and habitat use.
In a surprising finding, some marine organisms like crabs, shrimp, and lobsters build more shells when exposed to ocean acidification caused by elevated levels of atmospheric carbon dioxide. This may be due to the increased availability of dissolved inorganic carbon, which is beneficial for their skeleton formation.
Researchers found that antipsychotic medications increase levels of inflammatory markers, contributing to the risk of diabetes, hypertension, and heart disease in patients. The study highlights the need for monitoring cardiovascular risk markers in antipsychotic-treated patients.
A team of Wistar Institute researchers has identified a 29-gene signature in the blood that can indicate the presence of non-small cell lung cancer at its earliest stages. This discovery could lead to the development of a simple blood test for early-stage lung cancer detection, which would greatly improve treatment outcomes.
High urea levels in chronic kidney failure have been found to be toxic, leading researchers to suggest a potential new treatment strategy. Antioxidant therapy was shown to restore insulin sensitivity in mice with end-stage kidney disease. Similarly, targeting the molecular link Mdm2 may help prevent progression of late-stage metastatic...
A recent study suggests that mammography screening in young women with genetic or familial predisposition to breast cancer may increase their breast cancer risk. The study found that repeated exposure to low-dose radiation increases breast cancer risk among these women, particularly those under age 20 or with five or more exposures.
Research suggests that pushing toddlers to develop self-control too early may hinder brain development. Toddlers rely on brute-force competition to learn social conventions like language acquisition. Their immature brains are better equipped for learning through trial and error, allowing them to pick up skills effortlessly.
Researchers found that patients with high immune response during surgery recovered faster and had better knee function. Men were more likely to mount the beneficial stress response, leading to full recovery. The study suggests simple blood tests could predict patient recovery months after surgery.
Yehezkel Ben-Ari, founder of Inmed Mediterranean Institute of Neurobiology, receives the 2009 INSERM Grand Prix for his pioneering discoveries in brain maturation, epilepsy, and stroke. He is recognized for his contributions to fundamental, clinical, and therapeutic research.
Researchers found that lonely people tend to share their loneliness with others, gradually moving to the fringes of social networks. As a result, these individuals become less connected and more isolated.
A study found that morphologic changes on CT scans after bevacizumab-containing chemotherapy can predict overall survival in patients with stage IV colorectal cancer. The changes, including tumor size reduction and unique structural alterations, were strongly correlated with pathologic response and improved survival.
A new online program, Focus on Kids Online, helps separated parents build stronger relationships with their children. The program's effectiveness has been shown through improved parent-child relationships and awareness of separation-related problems.
Researchers found that anxiety sensitivity significantly predicted depression symptoms in above-average worriers. The fear of cognitive dyscontrol and publically observable anxiety symptoms specifically correlated with depression. Understanding this link may lead to new depression treatments by addressing anxiety sensitivity.
A study of 1,140 healthy young adults found that dream-enacting behaviors are more prevalent than previously thought. The most common behavior was 'fear,' followed by acting out emotions like anger and happiness.
Researchers found that naked mole rat brain tissue can survive for over half an hour without oxygen, which could lead to new treatment options for brain injuries caused by heart attacks, strokes, and accidents. This adaptation may also provide insights into how to prevent permanent human brain damage after temporary loss of oxygen.
Researchers found that the Big Freeze was triggered by a sudden freshwater pulse from Lake Agassiz in North America, which diluted the North Atlantic conveyor belt and led to rapid temperature drops. The climate took centuries to recover.
A recent study found that increasing patient responsibility for medical decisions decreases their willingness to accept risky treatments. Patients who were presented with choices reported higher worry about risks and lower uptake of treatment.
Typhoon Nida's maximum sustained winds are near 115 mph, with tropical storm force winds extending 150 miles from the center. NASA's CloudSat satellite captured a side look across Nida on Nov. 28, showing clouds over 15 kilometers high and heavy rainfall areas.
Researchers found that depressed women had no significant difference in weight loss success compared to non-depressed women. The key factor was attendance at a minimum of 12 sessions, regardless of depression status.
A study found that rural Medicare beneficiaries were 27% more likely to undergo total knee or hip replacement surgeries compared to urban recipients. Women and minorities showed significant disparities in both rural and urban areas. The study used the 2005 Medicare data and included over 6 million rural and nearly 38 million urban part...
Researchers have discovered that high levels of lead can slow the progression of amyotrophic lateral sclerosis (ALS), a neurodegenerative disease. This finding suggests that lead may activate a novel pathway able to reduce neuroinflammation and slow neurodegeneration in ALS patients.
Thomas Jefferson researchers have found a novel mechanism by which drugs can block HIV-1 from entering host cells, targeting the gp41 protein. The study reveals that fusion inhibitors induce irreversible deactivation of gp41, and suggests strategies to improve the effectiveness of existing treatments.
A recent study published in Financial Management argues that Chapter 11 reorganizations fail to offer a clean slate for firms to establish new capital structures. Despite substantial reductions in debt burden, firms still end up with higher debt ratios than industry norms.
Researchers aim to establish a standard for 'sufficiency' of information in friction ridge patterns, addressing the lack of quantifiable standards in the field. The goal is to improve accuracy and contribute to advancing science in forensic pattern recognition and comparison.
A large proportion of patients undergoing abdominal/pelvic CT scans receive unindicated and unnecessary additional image acquisition, leading to excess radiation exposure. The mean excess radiation dose per patient from unnecessary scans was found to be 11.3 millisieverts.
The Portable Lightweight Ubiquitous Gasket (PLUG) system, developed by Wil Laska, passed its second test in November 2009, demonstrating the ability to fill with water, float on flood currents, and adhere to breach sites. Four technologies were tested, including a large balloon or tube that worked as hypothesized.
Research documents the value of the human-animal bond in improving child development, elderly care, and rehabilitation outcomes. A growing body of evidence highlights the healing power of companion animals in reducing stress, providing affection, and fostering a sense of security.
Researchers at Monash University have developed a new way to increase the output of next-generation solar cells, achieving a three-fold increase in energy conversion efficiency. The breakthrough uses a new, more efficient type of dye that enables the operation of inverse dye-sensitised solar cells.
Clemson University researchers are studying safe storage of carbon dioxide in geological formations to reduce global warming emissions. They will focus on identifying conditions that may lead to leakage and developing techniques to minimize its impact.
Researchers use cryo-electron tomography to elucidate molecular architecture of Treponema pallidum, shedding light on cellular structure and movement. The study provides new understanding of how the bacterium attaches to human cells and moves with its flagella.
Scientists at MUHC and international colleagues discovered a chromosomal site controlling natural resistance to TB infection, found in 20% of individuals from high-exposure areas. The findings hold promise for preventing TB infection in the general population by stimulating resistance mechanisms.
Researchers found that 80% of rats survived cardiac arrest with chest compressions alone, but none survived without oxygen. Oxygen levels were essential for the animals to return to normal brain function at 72 hours.
Assessing biological processes under global warming requires accurate estimates of temporal changes in species. Long-term studies show that neglecting increasing seasonal climate lag can lead to distorted results.
A new self-assessment score has been developed to predict diabetes risk, showing promise as a simple and effective tool. Additionally, researchers are considering alternative bacteria, Fusobacterium necrophorum, for sore throat treatment due to its association with a rare but life-threatening complication, Lemierre syndrome. Furthermor...