A new treatment route for bovine spongiform encephalopathy (BSE) and its human form Creutzfeldt Jakob disease (CJD) may be closer based on new findings from the University of Leeds. Glypican-1 has been shown to cause abnormal prion proteins to rise, and reducing levels in infected cells can lower their levels.
The maize genome is a complex sequence of DNA that has been analyzed using a unique optical mapping facility at UW-Madison. The research advances knowledge of corn's ancestry and guides breeders in extracting increased productivity from the crop.
The $40-million-per-year frog leg trade may be a significant contributor to the spread of amphibian chytrid, a fungus causing respiratory and neurological damage. The Smithsonian team's research highlights the need for improved monitoring and regulation of the trade to mitigate disease risks.
Researchers at USC's CRES are evaluating robots as exercise coaches for adults of all ages, particularly the elderly. The study examines how physical presence affects robotic exercise motivation in older subjects.
Researchers have successfully generated human epidermis from human embryonic stem cells, providing a potential unlimited resource for temporary skin replacement in patients with large burns. The skin substitute was shown to be functional and structurally consistent with human skin after just 12 weeks of grafting onto mice.
The Lancet Infectious Diseases commentary highlights the lack of understanding on influenza transmission and its impact on healthcare worker protection. The article emphasizes the importance of source control, personal protective equipment, and immune status in preventing H1N1 spread.
A new study using DTI found correlations between brain areas and mathematical ability in children with FASD. The left parietal area is crucial for math tasks, while other regions may be unique to FASD. This research sheds light on the cognitive deficits of FASD and may lead to better treatment.
Researchers have identified and grouped the genes responsible for cell wall development in maize, enabling better study of biomass production. The discovery expands their ability to discover ways to produce biomass suitable for biofuels production.
Income transfers have limited impact in eradicating poverty; human capital development key to progress, experts argue. Strengthening education and work incentives for low-wage workers can assist families living in poverty.
The Ohio Research Association for Public Health Improvement (RAPHI) aims to investigate how public health does what it does, with an initial focus on improving services using information technology. The RAPHI project will advance RWJF's efforts to enhance the evidence base for public health policy and practice.
Scientists at the University of Michigan have determined the atomic-level structure of a SEVI precursor and found it damages cell membranes to make them more vulnerable to HIV infection. The study provides insights into how SEVI interacts with cell membranes, which may help in developing new treatments for AIDS.
Research published in Genome Biology found that Mexicans prioritize partners with Native American and European ancestry, while Puerto Ricans prefer those with African and European heritage. Ancestry has a stronger influence on romance than previously thought, with non-random associations of genes across generations.
Ann Veneman's leadership at UNICEF has sparked a debate about her potential second term, with some praising her focus on child survival while others criticize her lack of field experience. The Lancet editor Dr. Richard Horton calls for a transparent, merit-based appointment process to select the next Executive Director.
Geochemists discovered that ancient nickel ore deposits were formed by sulfur in the anoxic oxygen-poor atmosphere billions of years ago. Sulfur atoms traveled from volcanic eruptions, atmosphere, seawater, and hot springs to form the ores.
Researchers found that a social-skills intervention called Children's Friendship Training can lead to a decrease in hostile attributions or perceptions of children with PAE. The study suggests that such interventions may improve their social skills and relationships, leading to better outcomes.
Researchers detected SARMs, such as Andarine, on the black market, raising concerns about their potential misuse in sports. The study highlights the need for early implementation of screening for emerging therapeutic compounds in sports drug testing.
Researchers developed a statistical technique to scan genomes for specific gene-regulatory regions without prior knowledge of transcription factors. The approach has been experimentally validated in mouse and fruit fly genomes.
A statistical analysis found that FDA review intervals for new drugs remained unchanged from 1997 to 2006, despite increased investment in information technology. The study analyzed data on three main categories of new drugs and found no statistically significant reduction in review times.
The completed corn genome, published in Science, contains 32,000 genes and will aid in breeding high-yield crops. The sequence, a significant achievement after years of research, offers insights into plant genetics and opens new avenues for crop improvement.
Researchers analyzed DNA sequences from two inbred corn strains and discovered significant differences, including the presence of unique stretches of genetic material. This diversity is believed to be behind hybrid vigor, which can improve crop traits such as protein content or biomass production.
A new meta-analysis shows that women who quit smoking and receive treatment for weight control are more successful at controlling their weight gain and quitting cigarettes. This finding disproves current clinical guidelines that recommend trying to diet while quitting smoking simultaneously.
A team of scientists led by Ross Hardison has made significant discoveries about the mechanisms of gene regulation in red blood cells. They found that transcription factor GATA-1 controls the expression of over 2,600 genes by binding to specific sites on DNA.
Researchers have identified thousands of diverse genes in genetically inaccessible portions of the maize genome using new techniques. This study provides a foundation for uniting breeding efforts across the world and dissecting complex traits through genomewide association studies.
The National Evolutionary Synthesis Center is part of a major digital data initiative to improve access to Earth's biota and environment data. Dozens of institutions partner to provide secure, permanent access to biological and earth sciences data.
Researchers discovered that high-dose laser therapy stimulates melanoma tumor growth and histological alterations in mouse models. This finding underscores the need for caution when using laser therapy for skin cancer treatment.
A new study of Antarctica's past climate suggests that temperatures during interglacial periods may have been up to 6°C warmer than the present day. This finding could help understand rapid Antarctic climate changes and their connection to greenhouse gases.
A study at Henry Ford Hospital found that robotic surgery is effective in removing uterine fibroids regardless of patient weight. Obesity was not shown to be a risk factor for poor surgical outcome, contradicting previous concerns.
Researchers from UA and collaborating institutions deciphered the complete genetic code of maize, providing a comprehensive foundation to systematically study maize biology. The achievement aims to breed higher yielding, disease-resistant, and drought-tolerant cultivars.
A genetic tool used to identify species in seafood has found that nearly a quarter of what was labeled as tuna on sushi menus contained bluefin or escolar, two highly endangered species. The research highlights the need for clearer labeling and regulation to prevent economic fraud and protect endangered populations.
Researchers apply aerospace principles to create a durable and efficient wave-energy system that can be placed anywhere in the ocean. The system effectively cancels incoming waves, capturing their energy while flattening them out.
A new study reveals that a high score on the 'scale of craving' and an antisocial personality type are major contributors to relapse in cocaine users. The researchers analyzed 38 patients seeking treatment for cocaine abuse, finding impulsiveness and desire for new sensations also linked to substance use.
Researchers at I-STEM Institute have made significant breakthrough in stem cell research by recreating a whole epidermis from human embryonic stem cells. The goal is to provide an unlimited resource of cells as an alternative treatment for victims of third-degree burns and patients with genetic diseases affecting the skin.
A new study found that publicly blaming others increases the likelihood of spreading blame, as individuals try to protect their egos. Blame creates a culture of fear, leading to negative outcomes in organizations.
A University of Florida researcher is developing a micro-endoscope that can inspect tissues beneath the surface, revealing abnormal cell groups or growth patterns before they form tumors. This technology has shown promising results in laboratory tests and could allow for earlier detection and more precise tumor removal.
A synthetic bone matrix offers hope for babies born with craniosynostosis by replacing fused bones and encouraging natural bone healing. The biodegradable implant could eliminate the need for multiple surgeries, resulting in improved developmental outcomes.
A large trial has shown that patients with specific genetic makeups do not respond differently to treatment for asthma, regardless of their genotype. The study found substantial improvements in airway function when patients received longacting β2 agonists plus moderate-dose inhaled corticosteroids.
A new study reveals that sleep apnea is associated with an increased risk of high blood pressure, heart disease, and stroke in kidney transplant patients. The condition was found to be present in one in four individuals and more than doubled the risk of cardiovascular complications.
A new study found asthma to be a significant risk factor for severe disease in children with pandemic H1N1 compared to seasonal flu. Children with mild asthma also face risks and should be vaccinated for H1N1, according to researchers.
A new gene map has been developed to aid plant breeding efforts in maize, a major source of food and fuel worldwide. The map charts genetic diversity and recombination across the genome of 27 inbred lines, providing insights into complex traits.
The Spanish biotechnology industry should focus on the food and plant sectors to remain competitive. However, a study found that these sectors have less clout than English-speaking countries due to limited research and development investment. The sector's growth is hindered by high costs of developing new medicines.
A recent study found that only 60% of pregnant women in Eastern and Southern Africa were tested for HIV in 2007. The authors suggest that women may be avoiding testing due to opt-out policies or concerns about the stigma associated with HIV. This highlights the need for increased awareness and access to HIV screening in these regions.
Artificially introducing defects in nanotubes can enhance the development of supercapacitors, which combine the advantages of batteries and electrostatic capacitors. The researchers found that defects create additional charge sites, increasing stored charge capacity and power density.
The Elsevier journal Vaccine has released a supplement dedicated to vaccines for biodefense, showcasing significant advancements in vaccine development against diverse human and veterinary pathogens. The publication acknowledges the shift from traditional military focus to protecting both civilian and military populations.
Scientists have discovered a direct link between insulin and core body temperature, finding that insulin injection in specific brain areas increases metabolism, brown adipose tissue activity, and core temperature. The study suggests a potential therapeutic area for future drug design and new insights into obesity and diabetes.
The completed maize genome sequence reveals a complex genome with nearly as many genes as humans but substantially more complexity, containing about 85% repetitive sequences. This provides clues to genetic variability and gene function, enabling researchers to develop diverse maize hybrids that can adapt to environments.
Researchers have discovered a compound that prevents short circuits caused by damaged nerves, restoring function and transmitting signals more efficiently. The experimental drug, 4-aminopyridine-3-methyl hydroxide, may also be used to treat multiple sclerosis.
Researchers at UC Santa Barbara have demonstrated electrically manipulating quantum states of electrons in diamond crystals, a step towards developing quantum computers. The achievement enables the creation of magnetic fields large enough to change an atomic-scale defect's quantum state in under one billionth of a second.
A new home screening method for sleep disorders has been developed using a mobile phone or MP3 player, allowing people to record their sleep and analyze it at home. The method uses microphones to detect abnormal sleep structures and can provide significant medical breakthroughs, highlighting the importance of sleep quality and diagnosis.
A University of Missouri study found that framing health news releases to include conflict factors like health disparities and risks increases coverage in local black newspapers. This increased coverage raises awareness and can lead to better health outcomes in populations at risk for disparities.
A proposed wireless smart home system integrates RFID technology with Open Service Gateway Initiative (OSGi) to enable video monitoring and media access throughout the household or remotely. This allows users to check on devices, security alarms, and children's activities while away from home.
A team co-led by CSHL scientists published a reference genome of maize, revealing its complex DNA sequence and 'wonderful diversity'. The 2.3 billion base-pair sequence contains over 32,500 genes and provides a detailed reference manual for annotating the genome.
A study published in Biological Psychiatry found a significant positive association between phthalate exposure and ADHD symptoms in school-aged children. The researchers measured urine phthalate concentrations and evaluated symptoms of attention-deficit/hyperactivity disorder (ADHD) using teacher-reported symptoms and computerized tests.
Scientists discover that antibodies must precisely target the gp120 site of initial attachment on the viral spike to neutralize HIV. The new findings suggest a potential strategy for generating effective HIV-neutralizing antibodies, which could bring researchers closer to creating an HIV vaccine.
Yale researchers have discovered that a protein found in tick saliva helps protect mice from developing Lyme disease. The findings may spur development of a new vaccine against infection from Lyme disease, which is spread through tick bites.
The NIEHS has awarded 13 grants to develop better methods to assess exposure and health effects associated with nanomaterials. This research is essential for harmonizing results, forming a scientifically sound basis for hazard assessment.
Researchers found that gastroesophageal reflux disease spurs cytokine release, attracting inflammatory cells to the esophagus. This leads to damage characteristic of GERD, including symptoms like heartburn and chest pain.
Researchers found that a lower-calorie diet slows development of age-related conditions such as Alzheimer's disease, while a high-calorie diet accelerates oxidative stress. Dietary restriction activates transcription factor CBP, which regulates cellular function.
Researchers found that certain wild flax plants growing in poor soils can balance stress and reduce the risk of infection from a fungal pathogen. This suggests that stressful environments may be attractive to plants, providing a refuge from pathogens, but requiring adaptation to survive.
Researchers have developed new tire materials that improve rolling resistance and reduce friction, boosting mileage and cutting CO2 emissions by up to 20%. The new technology, however, requires proper tire inflation to unlock its full potential.
Patients with more bile duct visualization on imaging studies and fewer liver metastases had greater bile output after biliary drainage. However, daily observation of bile output and serum bilirubin reduction is crucial for determining procedure success.