A Phase IIIb study of Daytrana found significant improvements in ADHD symptoms in adolescents aged 13-17 years, with most adverse events mild to moderate. Pharmacokinetic data also showed similar exposure to d-MPH in both children and adolescents.
A recent study published in the American Society of Nephrology's Annual Meeting and Scientific Exposition found that kidney transplant survival rates vary by donor race, with non-black recipients experiencing lower survival rates when transplanted with black donors.
Researchers emphasize the importance of considering background rates of adverse events in H1N1 vaccination campaigns to prevent public panic. The study highlights that these background rates can provide valuable information on expected number of events occurring in the absence of any vaccination program.
A recent study found that a person's facial width-to-height ratio can be used to predict their tendency towards aggression. Volunteers rated the aggressiveness of male faces and found high correlation between the rating and the face's WHR, suggesting that subtle differences in face shape may affect personality judgments.
Researchers at Johns Hopkins School of Medicine found that cells in the retina can remain alive for many months and recover some or all normal function even without a proper blood supply. The study suggests that restoring blood supply to deprived regions of the retina may restore visual function.
China's new initiatives aim to replace 'paper tigers' with real conservation efforts, including improved policing of tiger trade and awareness-raising campaigns. The International Tiger Coalition welcomes China's engagement and recognizes the country's crucial role in wild tiger conservation.
A breakthrough in the fight against Hendra virus has been achieved with the development of a treatment that shows great potential to save lives. The treatment, administered after exposure to Nipah virus, protected animals from disease in a model.
Researchers analyzed data from 43 estimates of family wealth inheritance to find that technologies producing a society's livelihood are key factors in financial inequality. In contrast, hunter-gatherer societies exhibit lower levels of economic inequality due to the transferability of wits and social connections.
UT Southwestern researchers discovered that bacteria employ genetic circuits to generate diversity, increasing their chances of survival in unpredictable environments. This diversity allows individual bacteria to thrive under certain conditions, while others struggle, much like a diversified investment portfolio.
Researchers used PET scans to identify neuroinflammation in the brains of schizophrenics and migraine sufferers, shedding light on the underlying causes of these conditions. The findings have the potential to transform diagnosis and treatment options, particularly for schizophrenia.
A book by Dennis Shirley and Elizabeth MacDonald offers a new approach to supporting teachers, drawing on small group discussions, journal writing, and meditation. The authors argue that mindfulness can help teachers lead themselves and their students to a more satisfactory classroom experience.
Research by Stephen Piazza and Sabrina Lee found that elite sprinters' Achilles tendons translate 25% less than non-sprinters. Despite this mechanical disadvantage, sprinters still possess a powerful push-off due to slow-contracting muscles producing greater forces.
The Canon of Medicine, written by the Persian scholar Avicenna, contains detailed information on respiratory diseases remarkably similar to those used today. The article highlights Avicenna's work on respiratory diseases and conditions, including herbal and non-herbal treatments, which are still valid with modern science.
A new study demonstrates the effectiveness of immunotherapy using specialized white blood cells to prevent or treat EBV-lymphoma in patients who have received a hematopoietic stem cell transplant. The therapy achieved sustained complete remission in 85% of treated patients and long-term protection for up to nine years.
A Lancet paper stresses the importance of accounting for background rates of adverse events to ensure accurate vaccine safety assessments. The study found that public concern over coincidental medical events can interfere with vaccine programs, even if the vaccine is not the cause.
A study found that dialysis patients who travel on vacation risk infections, anemia, and other complications. Travelers are advised to take extra precautions to minimize these risks.
The SMU Geothermal Lab has been awarded a $5.25 million grant by the US Department of Energy to provide data for the National Geothermal Database. The project aims to expand geothermal production in the US, providing critical information on Enhanced Geothermal Systems and oil & gas resources.
A new optical system can simultaneously image electrical activity and metabolic properties in the heart, providing a platform for testing new treatments for arrhythmias. The system could lead to a better understanding of the relationship between metabolic disorders and heart rhythm disturbances.
Researchers at USU and Australian Animal Health Laboratory demonstrate effective therapy against Nipah virus using a human monoclonal antibody, m102.4. The treatment showed promising results in animal models, offering hope for preventing and treating diseases caused by the deadly viruses.
The Systolic Blood Pressure Intervention Trial (SPRINT) aims to determine whether maintaining blood pressure levels below current recommendations reduces cardiovascular and kidney disease risk. The nine-year trial will enroll over 7,500 participants aged 55+ with high systolic blood pressure.
Researchers found that material possessions are easily passed on, while social networks and foraging abilities are harder to transmit. Societies with a strong emphasis on material wealth tend to be the most unequal.
Researchers found that patients with higher kidney function at the time of transplant did not have a significant advantage in terms of long-term health. However, they did require less dialysis and were less likely to experience kidney rejection after transplantation.
The National Institutes of Health has awarded $75 million to establish a medical research consortium at Charles Drew University and three other historically black institutions. The grant will support clinical and translational research focusing on cardiovascular disease, diabetes, and HIV/AIDS, aiming to develop innovative solutions fo...
A diet high in fructose increases the risk of developing high blood pressure. Studies found that consuming more than 74 grams per day of fructose led to a higher risk of hypertension, with significant associations seen across various blood pressure levels.
Researchers at the University of Washington have developed Open Data Kit, a versatile platform for collecting, storing, and analyzing mobile data. Organizations worldwide are using it to gather information on global health, environment, and human rights issues, enabling evidence-based decision-making.
Regular Tai Chi sessions improve physical function and reduce knee OA pain in elderly patients. The study found significant decreases in pain and improved physical function, depression, and overall health in those practicing Tai Chi.
A controversial theory suggests that vaccinating children against seasonal flu could prevent the development of heterosubtypic immunity to pandemic strains. However, experts disagree, arguing that vaccination is a definite benefit for preventing seasonal flu infections. The debate highlights the need for more effective influenza vaccines.
A review of 66 clinical studies on biofield therapies like Reiki and therapeutic touch found moderate to strong evidence for reducing pain and agitated behaviors in patients, but inconclusive effects on fatigue and quality of life.
The launch of SMOS will improve understanding of water transportation around the Earth, leading to more accurate weather forecasts and climate simulations. Global measurements of salinity and soil moisture will also inform predictions of floods, droughts, and future climate changes.
A University of Pittsburgh-led team creates a nanoparticle-based coating that thwarts the buildup of ice on solid surfaces, offering a potential solution to prevent freezing rain damage. The coating, inspired by water-resistant lotus leaves, uses microscopic ridges to reduce surface area for ice adhesion.
Shire presents new scientific data on its ADHD portfolio, including INTUNIV, Vyvanse, and Daytrana. The company's ADHD business unit is committed to advancing treatment research and developing safe and effective treatments.
A new celestial map, ICRF2, provides precise location of the Earth's orientation for GPS navigation. The map uses observations of approximately 3,000 quasars and a network of radio telescopes to achieve high accuracy, with uncertainties as small as 40 microarcseconds.
A U-M study found that exposure to androgen hormone relocates pieces of chromosome near each other, setting the scene for gene fusion in prostate cancer. This finding may lead to new screening tools or prevention strategies.
Two UCSF teams, one for diabetes and one for brain tumors, have received grants from the California Institute for Regenerative Medicine to advance stem cell-based therapies. The goal is to file new drug applications with the FDA within four years, driving potential therapies toward clinical trials.
Researchers from Queen Mary University of London have identified a gene called nocte that interferes with the fly's ability to synchronize its body clock using temperature signals. Disabling this gene prevents both synchronization to light-dark cycles and temperature changes.
A study by the Cell Transplantation Center of Excellence found that autologous brain cell transplants can provide brain protection and repair neural damage in donor primates. The cells survived at an impressive 50% rate for four months post-implantation, offering a promising new approach to treating neurological disorders.
A study published in BMC Psychiatry found that depression and alcohol misuse are more common mental health disorders among UK Service personnel returning from Iraq and Afghanistan. The study also reveals that reservists are at a greater risk of psychiatric injury than regular personnel.
Researchers found left side grafting has lower risk to donors compared to right lobe grafts, and recipients can achieve comparable survival rates with smaller graft sizes. The study suggests using left side grafts more frequently in adult-to-adult liver transplantation to reduce donor risk.
Group education of patients' relatives and friends can improve their willingness to consider kidney donation. The study found that group discussions increased the number of potential donors among participants.
A new study reveals a relationship between the evolution of the influenza virus and immunization rates needed to prevent outbreaks. The research team found that the degree of variability in population immunity plays a crucial role in determining the risk of an outbreak.
The 4th annual Katz Prizes in Cardiovascular Research recognize outstanding contributions by senior scientist Elizabeth G. Nabel and young investigator John P. Morrow, who are judged by an independent panel of peers.
Using precision techniques, researchers pinpointed a single copper-oxide layer as the key to superconductivity in a material. The discovery could lead to precision engineering of ultrathin films with tunable superconductivity for higher-efficiency electronic devices.
Researchers found that trophoblast stem cells (TSCs) can survive in female mice livers without ovarian hormones, but not in male liver's even after castration. This study suggests a new approach for therapeutic cell transplantation using TSCs.
A UC Riverside-led study found oxygen production via photosynthesis occurred in Earth's oceans at least 100 million years before the GOE, affecting ocean chemistry and potentially stimulating eukaryote evolution. The research suggests that even low concentrations of oxygen can have profound effects on ocean chemistry.
Researchers at Johns Hopkins Medicine have identified over 300 proteins that control genes, a newly discovered function for previously known proteins. These 'moonlighting' molecules may play a key role in human complexity, with potential implications for understanding gene regulation and cellular behavior.
A team of researchers at the University of Pennsylvania School of Medicine has identified a small molecule that inhibits heat shock protein HSP70, which is overexpressed in tumor cells. The inhibitor, called PES, blocks HSP70's stress-relieving functions and induces cell death by disrupting autophagy.
Researchers from the University of Texas M. D. Anderson Cancer Center have discovered that Th17 cells can awaken the immune system to fight cancer. In preclinical studies, mice with normal levels of Th17 showed suppressed tumor growth in lung metastatic melanoma tumors, while those without Th17 experienced aggressive cancer growth.
Researchers at Texas A&M University have developed a new spin-based device that can process information more efficiently and cool laptops. The device uses electrons' spin direction to record and transmit information, achieving operational temperatures of room temperature.
A comprehensive review of flu seasons past reveals that pregnant women are at significant risk for serious flu-related illnesses and complications, which far surpass the risks associated with injectable vaccines. The study confirms existing CDC recommendations for prioritizing pregnant women in flu vaccination.
INTUNIV demonstrated significant efficacy in reducing symptoms of attention deficit hyperactivity disorder (ADHD), particularly oppositional symptoms, in children and adolescents. The study showed improved symptoms as measured by the Conners' Parent Rating Scale-Revised: Long Form (CPRS-R:L) and ADHD Rating Scale-IV (ADHD-RS-IV).
A new swine flu test developed by TGen can quickly inform doctors about the strain of flu and whether it may be resistant to oseltamivir, a primary anti-viral drug. The test has been shown to be effective in detecting resistance to Tamiflu in H1N1 virus strains.
The university's partnership with UCLA will enhance its capability to conduct high-quality cancer research, recruit more investigators, and strengthen outreach programs. The grant will also enable the university to add students and clinical fellows as future cancer researchers.
The new center will support partnerships with community-based organizations to conduct innovative research and develop effective programs to eliminate health disparities. It will also expand training and technical assistance services, including multilingual materials and distance learning programs.
Certain gases have a significantly more powerful warming impact when linked with aerosols, amplifying their effect. Methane and carbon monoxide can reduce sulfate aerosol production, leading to increased warming.
New research suggests that prolonged space travel weakens human immune systems, making astronauts more susceptible to disease. The study also found that microorganisms such as bacteria can grow more rapidly in space conditions, increasing the risk of contamination and serious infection.
Researchers have confirmed that the Greater Noctule bat (Nyctalus lasiopterus) inhabited northeastern Spain during the Late Pleistocene period. The discovery of fossils at the Abríc Romaní site in Barcelona sheds light on the species' wider geographical range, which has declined due to vegetation reduction.
Researchers designed smartphone games and easy-to-use logging features to help elderly Chinese diabetics manage their health. Initial studies of the system, called CADA, show promising results, enabling diabetics to track vital information for better doctor-patient interaction.
A study by Johns Hopkins Medicine found that uninsured children were 60% more likely to die in the hospital than those with insurance. Researchers estimate that thousands of children may have been saved if they had health coverage, highlighting the need for healthcare reform.
The study aims to determine if lowering systolic blood pressure in hypertensive patients can reduce the incidence of cardiovascular and kidney disease, as well as slow cognitive decline. The results will be used to reevaluate optimal blood pressure levels and establish new guidelines for healthcare providers.
A new study suggests that the proposed bundled payment system for dialysis could have a significant impact on dialysis units nationwide. The research found that facilities in certain regions, particularly the south and east, are likely to face adverse financial consequences under the new plan.