Researchers have discovered that the Shp2 protein plays a critical role in controlling the pathways that decide whether human and mouse embryonic stem cells differentiate or self-renew. The study found that Shp2 acts as a coordinator to fine-tune signal strength, providing insight into fundamental signaling mechanisms.
Researchers dispute a recent study that creates a different family tree for the hippo, arguing that it ignores important DNA data. Hippos are closest living relatives of whales, according to most DNA evidence from the last 12-13 years.
A recent study found that media health reporting is improving in terms of accuracy, with online news services showing a notable five percent increase over four years. However, the overall quality of health reporting remains poor, particularly for commercial current affairs programs.
Researchers at Johns Hopkins University developed a lab-on-a-chip device that can study cell detachment, a critical step in cancer metastasis. The device helps understand the molecular mechanisms behind cancer cells' ability to break free from tissue, which could lead to better therapies.
The University of Pittsburgh will focus on developing new strategies to prevent and control antibiotic-resistant bacterial infections, such as C. difficile, A. baumannii, and MRSA. The four-year grant aims to improve infection surveillance and reduce healthcare costs associated with these resistant infections.
A study found nearly 100 genes that support the replication of HCV and show that blocking several of them can suppress viral replication in cultured cells. Targeting these human genes could provide an alternative therapeutic strategy for patients with chronic HCV infection.
Researchers estimate that around 6.5 million older adults with low cholesterol and high C-reactive protein levels might benefit from statin therapy to prevent cardiovascular events. Expanding prescribing criteria to include CRP levels could potentially prevent thousands of heart attacks, strokes, and deaths each year.
A special issue explores how global institutions shape domestic R&D policies, and how international sourcing of technology impacts innovation. The articles present diverse methods and data to improve understanding of the interplay between national institutions and the globalized political economy.
The 5th annual Templeton-Cambridge Fellowships in Science & Religion were awarded to 10 notable journalists from the US, UK, and Canada. The two-month program includes seminars and discussion groups with prominent experts, aiming to promote informed public discussion of science and religion.
Dr. G. V. P. Reddy's $60,000 SARE grant will educate agricultural professionals on semiochemicals for monitoring and controlling pests like banana root borer and New Guinea sugarcane weevil.
Researchers have identified genetic markers associated with aggressive head and neck cancer, specifically miR-205 and let-7d. These microRNA levels can predict poor survival outcomes and may lead to targeted treatment options.
A study published in the Journal of Pediatric Psychology found that daily exercise for 20-40 minutes significantly improved depressive symptoms and self-esteem in overweight children. The researchers noted a dose response benefit, with more exercise leading to greater benefits.
Patients with gastrointestinal stromal tumor (GIST) who received adjuvant imatinib after surgery experienced increased recurrence-free survival compared to those given placebo. Imatinib significantly improved recurrence-free survival at one year, with the most impact on tumors over 10cm in size.
A new experimental vaccine has shown promising results in preventing cytomegalovirus (CMV) infection in infants, reducing the risk by 50% compared to a saline injection. The vaccine was given to 441 CMV-negative women and found to be safe with minimal side effects.
Scientists at The University of Nottingham have uncovered a vital new biological clue that could lead to more effective treatments for CNS PNETs, a type of brain tumour predominantly occurring in children. The research found that WNT pathway activation is linked to patient survival and may represent an important new target for treatment.
A new study by psychologists at the University of Georgia reveals that minority employees feel less committed to their work when white employees promote colorblindness. In contrast, when white workers champion multiculturalism, minority peers feel more connected to their jobs.
A new study by the University of Toronto's Rotman School of Management found that exclusive marketing contracts are more lucrative when firms and products have low market differentiation. By analyzing a real-world example, researchers discovered that non-exclusive contracts can be beneficial in highly competitive markets.
Beta-1 integrin's role in regulating cell behavior and extracellular matrix assembly is crucial for understanding diseases like cancer and fibrosis. The study identifies a key protein, talin, involved in controlling fibronectin fibril formation.
A Kansas State University researcher found a link between employee psychological well-being and cardiovascular health, using an efficiency-based measure called pulse product. Those with higher levels of psychological well-being had lower pulse product scores, indicating a lower risk for cardiovascular disease.
The University of Washington's DEIMOS acoustic package has joined the Monterey Accelerated Research System (MARS) ocean observatory to monitor movements of fish and zooplankton in Monterey Bay. The system uses an echo sounder to reveal what's in a narrow cone of water above the instrument, providing insights into ocean life dynamics.
A new MIT study reveals our impaired ability to recognize faces in photographic negatives may lie in the brain's reliance on a certain kind of image feature. The research suggests that facial processing regions in the brain are more active when looking at contrast chimera images than pure negatives.
A National University of Chicago study found that elderly individuals experiencing loneliness face higher risks for poorer mental and physical health. Those who adapt to alone time without developing strong feelings of loneliness tend to fare better.
A major US study of 75,000 men found that annual prostate cancer screening led to more diagnoses but not fewer deaths. The study suggests that men with a short life expectancy may not need screening, and further research is needed to determine its benefits and harms.
A Phase II clinical trial found that the vaccine showed efficacy in mothers, with a significantly lower rate of CMV infection. The study used an experimental vaccine made from glycoprotein B and included an adjuvant to improve immune response.
The global financial crisis is expected to exacerbate poverty for vulnerable households in developing countries, threatening progress towards reducing extreme poverty. Experts will discuss potential outcomes and steps to mitigate the impact on the most disadvantaged populations.
Researchers used the pursuit-evasion game 'Marco Polo' to create a system for controlling moving robots that can autonomously detect and capture other moving targets. The system, which uses multiple sensors and cell decomposition algorithm, has broad applications in security, environmental monitoring, and tracking endangered species.
A study by Georgia State University found that less than half of IRB policies discuss finder's fees as conflicts of interest. Only 26% of IRBs mentioned potential conflicts when physicians recruit their own patients, highlighting a gap in guidance.
A new study by Queen's University researchers found that children who engage in longer periods of sustained physical activity are less likely to become obese. The study analyzed data from over 2,400 youth aged eight to 17 and confirmed the benefits of sustained, rather than sporadic, exercise.
Researchers at the University of Innsbruck have discovered that BASP1 inhibits uncontrolled cell growth and proliferation caused by the Myc gene, which is a key factor in tumor development.
A new study finds that black girls are 50% more likely to exhibit bulimic behavior, including binging and purging, compared to white girls. The study also reveals that girls from low-income families are significantly more likely to experience bulimia than their wealthier peers.
A new study finds that X-ray-guided spinal tap procedures fail in about 60% of young infant cases and cause bleeding in 25% of infant cases. For patients over 80, the risk of bleeding doubles, but can be reduced by inserting the needle in the middle of the lower back.
Citizen scientists transcribe historical bird records into scientific database for better understanding of climate change effects on bird populations. The USGS North American Bird Phenology Program aims to unravel the impact of global warming on bird behavior and migration patterns.
An international team of astrophysicists used simultaneous observations from optical, X-ray, and gamma-ray telescopes to uncover complex changes in PKS 2155-304's radiation. The findings challenge current theories on how radiation is generated in blazars.
The study found that PSA screening can reduce prostate cancer deaths by 20%, saving one life for every 1,408 men screened. The European Association of Urology's largest prostate cancer screening study provides robust evidence for the effectiveness of screening on prostate cancer mortality.
Dr. Roger Zebazé's project will investigate the structural causes of childhood fractures, aiming to understand bone fragility and devise preventative measures. The IOF-Servier Young Investigator Research Grant provides €40,000 support for innovative osteoporosis research.
A study found that proteinuria levels are higher in children with low glomerular filtration rates and non-Caucasian race, suggesting genetic or environmental factors. The study also found that patients taking renin-angiotensin system antagonizing drugs had lower levels of proteinuria compared to those not on these medications.
The newly-laid MARS cable enables the use of MOBB's broadband seismometer data in real-time with other land-based stations to determine earthquake locations and mechanisms. This improvement aims to enhance understanding of the San Andreas fault system and provide early warnings for ground shaking.
A new study from University of Pennsylvania School of Medicine identifies genes associated with the BRCA1 protein and their involvement in the DNA repair pathway. MERIT40, a previously unknown protein, was found to work with BRCA1-RAP80 complex to achieve DNA repair.
Researchers at Northwestern University have developed a high-performing photoconducting material using zinc oxide, offering environmentally benign chemistry, low-cost production, and high detectivity. The material's novel architecture enables efficient electron transport, comparable to amorphous silicon.
A new study by Michigan State University found that charter school students are 7-15% more likely to graduate from high school and attend college compared to their traditional public school counterparts. This positive trend suggests improvements in graduation rates for charter schools, but mixed results for test scores and other outcomes.
Heart failure is striking younger African-Americans, with one in 100 developing the condition at an average age of 39, compared to Caucasians in their fifties. The study emphasizes the importance of addressing risk factors like hypertension and obesity in young adults to prevent heart failure.
The Office of Naval Research (ONR) has partnered with General Motors to test advanced fuel cell vehicles at Camp Pendleton, which may offer benefits such as reduced air pollution and increased power potential. The partnership aims to advance technology that can also address energy challenges for the public.
A pilot study demonstrates a novel, low-cost technology that automatically monitors hand hygiene dispenser use before and after patient room entry. The system, using Zigbee technology, accurately identified over 90% of subjects entering and exiting rooms for extended periods.
A nationwide research team has identified and mapped 55,000 gene enhancers, revealing their critical role in cell-type-specific gene expression. The study broadens our understanding of the human genome and its regulation.
Scientists successfully produced biologically-active interleukin-10 in genetically modified tobacco plants, offering a potential new treatment for autoimmune diseases. The transgenic plants can produce the active cytokine at high levels without lengthy extraction and purification processes.
Researchers found depressed individuals correctly identified more negative beans than non-depressed peers, but struggled with positive beans. The study suggests depressed people may have a bias against learning good information, which could impact treatment.
Research from the University of Washington and Monell Center found that children's high growth rate is linked to their heightened liking for sweetness. Children prefer higher levels of sweetness as their physical growth increases, but this preference declines as growth slows down.
Professor Jean-Yves Reginster, a renowned researcher and former IOF General Secretary, has been honored with the Pierre Delmas Award. He is being recognized for his significant contributions to the advancement of osteoporosis research.
A recent study published in Annals of Oncology found that a biopsy of suspected recurrent breast cancer can lead to significant changes in treatment. In some cases, the biopsy showed that the woman did not have an advanced cancer, but a benign condition.
Researchers found two widely-prescribed anticonvulsants may lead to increased cholesterol, C-reactive protein and other markers of cardiovascular disease. Switching patients to newer drugs resulted in significant declines in these markers.
Researchers have developed new medical adhesives using marine mussel glue and inkjet technology that are non-toxic, biodegradable and precise, promising improved wound repair and reduced scarring in surgeries. The adhesives could replace traditional sutures, reducing complications and improving patient outcomes.
A new method developed at the Physikalisch-Technische Bundesanstalt (PTB) improves the stability of caesium fountain clocks by reducing measurement times and increasing accuracy. This is achieved through the use of a microwave oscillator stabilized with lasers, allowing for more precise frequency measurements.
Dr. Athena Papas receives IADR's highest honor for her outstanding research on dry mouth, tooth sensitivity, and oral health in cancer patients. Her nearly 30-year career has secured over $20 million in grant funding.
The GOCE satellite will study global ocean currents, ocean topography, and the structure of the Earth's crust with unprecedented precision. The satellite's high-resolution gravity mapping will enhance our understanding of climate change.
Researchers have developed a synthetic wood substitute made from a new biodegradable plastic that could replace petrochemical plastics in building materials and disposable water bottles. The material is durable, recyclable and can be produced faster than wood or trees.
Researchers found that collagen injections can improve symptoms of stress urinary incontinence (SUI) in some patients, even after surgical treatment fails. The procedure involves injecting collagen into the tissue surrounding the urethra to tighten the sphincter and prevent leakage.
A study found that modafinil increases dopamine levels in the brain and blocks dopamine transporters, raising concerns about its potential for abuse. The drug's effects on dopamine may be linked to its therapeutic actions.
Dr. Lior Shapira has received the IADR Basic Research in Periodontal Disease Award for his groundbreaking work on the mechanisms of inflammatory responses in periodontitis. He has published over 100 scientific articles and chapters, and continues to serve as a prominent figure in the field.
Researchers found frankincense oil to discriminate between normal and cancerous bladder cells, kill cancer cells, and suppress growth by arresting cell cycle progression. The oil may represent an inexpensive alternative therapy for patients with bladder cancer.
A forthcoming study by North Carolina State University economists found that players who perform well early in the season have an incentive to maintain their high level of performance into the middle part of the season. This is because they are competing for a top-30 finish and a spot in the Tour Championship, which guarantees them mon...