Scientists at Brookhaven National Laboratory have developed a DNA-based assembly line for predictable, high-precision nano-construction, enabling the rapid assembly of new biosensors and solar cells. By controlling DNA interactions, they can regulate interparticle distances and assemble nano-objects into complex structures.
Clostridium perfringens produces a potent toxin that promotes tissue damage, inflammation, and heart effects, posing significant risks to poultry and diabetic individuals.
Researchers compared two groups of patients with coronary artery disease and severe heart failure, finding that surgical ventricular reconstruction made no difference in key clinical outcomes. The study's findings challenge conventional wisdom that making the heart smaller and more normal makes it stronger.
A study at Cincinnati Children's Hospital Medical Center found that lower-income families and African-Americans have a lower quality of life after cardiac surgery. The Pediatric Cardiac Quality of Life Inventory (PCQLI) was developed to assess health-related quality of life in children and adolescents.
A phase II study showed relaxin reduces cardiovascular mortality and shortness of breath in heart failure patients with high blood pressure. The drug also improves other clinical endpoints, including hospital stay and days alive out of hospital.
Researchers found that microbes in coastal mudflats can rapidly degrade petrochemical residues in aerobic conditions, but slower in anaerobic conditions. The study suggests using these microbes as a natural way to clean up pollution in estuaries.
A study by Wan Li Low and colleagues found that combining low concentrations of tea tree oil and silver increases antimicrobial activity against pathogens like Staphylococcus aureus and Candida albicans. This method allows for controlled release and may lead to safer, over-the-counter antiseptic compounds.
Researchers at Baylor College of Medicine identified a proteinase called MMP7 that activates an allergic response in the lung. A form of vitamin A made in the lung also plays a critical role in dampening inflammation, and suppressing its production restores asthmatic symptoms.
Researchers at University College Dublin found that adding fish oil to the diet of cattle reduced methane emissions by affecting the gut bacteria. This discovery offers a targeted approach to mitigating methane's potent greenhouse gas effects.
Dr. Roland Romeiser, a UM Rosenstiel School researcher, has been awarded a $500,000 ONR grant to develop 'along-track InSAR,' a new satellite technique that maps surface currents in rivers and oceans. This technology will aid in monitoring global river runoff and bathymetric changes.
The discovery of slow-growing Mycobacterium tuberculosis bacteria in TB patients' lungs may lead to the design of new anti-TB drugs. These slowly growing bacteria are non-responsive to treatment with isoniazid, contributing to prolonged treatment times and relapse rates.
Researchers at Scripps Research Institute have developed a new high-throughput screening technique that allows identification of potential cancer and other treatments. The technique, called fluopol-ABPP, uses fluorescence polarization to rapidly detect inhibitors for uncharacterized proteins.
Researchers found drug-resistant viruses can circulate between individuals who haven
A Henry Ford Health study found that increasing exercise parameters improves quality of life and reduces hospitalization and death risk in heart failure patients. Patients who exercised for 25 minutes at moderate intensity lowered their estimated risk by 10-25 percent.
Researchers have discovered two efficient biomarker applications that promise even earlier diagnosis and improved treatment of heart failure. Biomarkers N-terminal pro-B-type natriuretic peptide (NT-proBNP) and cystatin C can identify patients at high risk, enabling targeted care and reducing healthcare costs.
Researchers found that individuals with autism tend to stare at people's mouths rather than their eyes due to the attraction of audiovisual synchrony. This phenomenon is more pronounced in toddlers with autism, who exhibit a strong preference for lip-sync, whereas unaffected peers focus on socially meaningful movements.
Researchers at the NIH/National Human Genome Research Institute have discovered a new tumor suppressor gene, MMP-8, that helps prevent melanoma growth. The finding may lead to more individualized cancer treatment strategies and improved outcomes for patients.
Researchers have identified the DegU protein as crucial for bacterial decision-making in biofilms. This protein enables individual bacteria to switch between different physiological processes, such as movement and biofilm production, in response to environmental conditions.
A new environmentally friendly coating has been developed using spores from a bacterium to prevent microbial corrosion of metals in seawater. The coating was found to be substantially more effective than existing treatments and could be heat cured at temperatures up to 90°C.
Chemists at the University of Illinois developed a molecular force probe to study the effects of stretching molecules, revealing counterintuitive results about chemical bond breaking rates. The technique allows researchers to explore the properties of transition states governing chemical transformations.
Researchers found that reducing high sensitivity c-reactive protein (hsCRP) levels and LDL cholesterol significantly reduces vascular events. Achieving both targets resulted in the largest reduction in cardiovascular risk, highlighting the importance of addressing inflammation in statin therapy.
Severe injuries on battlefields increase risk of multidrug-resistant bacterial infections in war-wounded soldiers. Effective personal protective equipment and medical care have improved survival rates but not mitigated the risk of wound infections.
Researchers found that dust blown to Antarctica from Patagonia provides vital information about glacier activity and past climates. The study suggests that the coldest periods of the last ice age correspond with the dustiest periods in Antarctica's past.
Researchers at Mayo Clinic have discovered the molecular interplay that enables invasive tumor cells to move and invade other parts of the body. By manipulating this process, they hope to develop treatments to stop cancer from spreading.
A large international clinical trial found that surgical ventricular reconstruction did not reduce deaths and hospitalizations in heart failure patients, nor improve quality of life compared to bypass alone. The study, STICH, included 1,000 patients from 96 medical centers in 23 countries.
Researchers at Vanderbilt University Medical Center discovered that the clinically available drug flecainide prevents potentially lethal arrhythmias in patients with CPVT. In two patients, flecainide prevented exercise-induced ventricular arrhythmias and allowed them to live normal lives.
Researchers identified a new cancer gene, UTX, common to many cancers and affecting gene regulation. The UTX protein modifies chromatin structure, altering histone modification and impacting gene activity.
Repeatedly, molecular microbiological techniques have found changes in soil bacterial communities after antibiotic use in intensive livestock production. Bacteria involved in the nitrogen cycle are particularly affected, with persistent changes even after antibiotics break down.
Research from the University of Rochester found that action video games can improve contrast sensitivity by 58% by training the brain to process visual information more efficiently. This finding suggests that gaming may not be harmful for vision and could potentially complement eye-correction techniques.
Dr Crouch, a 2009 Advancing BioBusiness Award winner, seeks to improve scientific discovery in Australia through state-of-the-art assays and automation. He hopes to develop new tests for bio-markers of diseases like cancer, improving the efficiency of research in Australian university laboratories.