Researchers have discovered eight gene mutations linked to medulloblastoma, the most common childhood brain cancer. The study, funded by the Canadian Cancer Society, may lead to better drug treatments and improved survival rates for children with this disease.
SourceCanadian Cancer Society·JournalNature Genetics·DateMar 8, 2009
Researchers have identified two key brain regions responsible for forming first impressions, including the amygdala and posterior cingulate cortex. These regions process emotional and value-based information to form a quick and lasting impression of others.
SourceNew York University·JournalNature Neuroscience·DateMar 8, 2009
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The EORTC-NCIC trial found that adding chemotherapy to radiotherapy significantly increases survival in glioblastoma patients, with improved outcomes seen across all clinical prognostic subgroups. The study suggests testing tumour MGMT gene methylation status to identify patients most likely to benefit from this treatment.
SourceThe Lancet_DELETED·JournalThe Lancet Oncology·DateMar 8, 2009
Researchers at the University of Pittsburgh School of Medicine discovered a molecular '2-step' process that may lead to protein clumping in Huntington's disease. The study found that a slight lengthening of the polyglutamine sequence disrupts neighboring regions, initiating aggregation behavior. This discovery could provide new targets...
SourceUniversity of Pittsburgh Schools of the Health Sciences·JournalNature Structural & Molecular Biology·DateMar 8, 2009
Researchers at the London Centre for Nanotechnology have discovered a novel one-dimensional ice chain structure built entirely from pentagons, challenging the long-held assumption that hexagons are the building blocks of ice. This discovery has significant implications for understanding hydrogen bonding at interfaces and may lead to ne...
SourceUniversity College London·JournalNature Materials·DateMar 8, 2009
Scientists have successfully replaced damaged brain tissue in rats with stem cells, filling cavities within 7 days. The new tissue interacts with the host brain and can be gradually replaced by natural processes.
SourceBiotechnology and Biological Sciences Research Council·JournalBiomaterials·DateMar 8, 2009
A genetic variant on chromosome 8 is found to occur significantly more frequently in people with cleft lip and palate than in the control group. The study suggests that genes may play a far more important role in the formation of clefts than previously thought.
SourceUniversity of Bonn·JournalNature Genetics·DateMar 8, 2009
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Researchers at UC San Diego School of Medicine identified CD98hc protein as essential for B lymphocyte division and antibody secretion. The protein supports integrin signaling, which controls cell migration, survival, and proliferation.
SourceUniversity of California - San Diego·JournalNature Immunology·DateMar 8, 2009