A study found that long-term cumulative mortality was highest among patients with system delays of 121-180 minutes, increasing by 28.1% and 30.8% respectively. System delay was independently associated with mortality in multivariate analysis.
Researchers discovered that the Prox1 gene plays a crucial role in developing and maintaining cells vital for making new memories throughout life. The study revealed a novel feedback mechanism regulating differentiation of adult neural stem cells.
A team of researchers at Tel Aviv University has developed genetically mutated mice to study Vanishing White Matter disease, which destroys brain myelin. The new tool allows for the first time to follow the exact process of myelin destruction, providing valuable information about the molecular mechanisms of the disease.
A Brigham Young University study shows that voters are less objective in evaluating their governor's economic performance if the White House is controlled by the opposing political party. The analysis found that voters overestimate the policy success of the level of government their preferred party controls, leading to rosier assessmen...
Researchers are investigating the effects of radiation on human bone strength to improve treatment for cancer patients with bone metastases. The study aims to establish the mechanical strength of bone before and after stereotactic radiosurgery, which has been shown to cause high fracture rates in post-treatment patients.
A new statistical method confirms that mitochondrial Eve, the mother of all humans, lived around 200,000 years ago. The study compared 10 human genetic models and found that they produced similar estimates, suggesting that refining assumptions beyond a certain point is not crucial in capturing the big picture.
Researchers found that long-lived aspen clones experience reduced sexual performance and increased risk of extinction with age. The study, published in PLOS Biology, used molecular clock estimates to determine the age of individual clones and measured male fertility.
A predictive model using factors like age, blood pressure, and heart rate accurately predicted the development of critical illness in patients who received out-of-hospital emergency care. The study found that hospitals varying widely in quality of critical care could improve outcomes for critically ill patients by concentrating care at...
Astronomers detected X-ray eclipses from a fast pulsar, shedding light on compressed matter and testing relativity. The system's unique properties revealed the size and mass of the companion star with unprecedented accuracy.
A new report from Johns Hopkins Bloomberg School of Public Health finds that trauma center care is cost-effective for patients with severe injuries and those younger than 55. The study estimates that trauma center care saves lives at a lower cost per life-year gained compared to non-trauma center care.
A study by University of Cincinnati professor David Maume found that men who worked late shifts believed it negatively impacted their marriages, whereas most women saw rotating work schedules as a strain on their marriages. Women reported greater difficulty in caring for and nurturing family members due to their schedules.
Research conducted by the USDA found that low levels of folate are associated with symptoms of dementia and poor brain function, as well as depression in women. The study also identified a protein called holoTC as a potential key to detecting cognitive decline earlier.
A researcher at Michigan State University is studying the role of the innate immune system in protecting against lung cancer. Alison Bauer's work may lead to new approaches to prevent, identify and treat lung cancer.
A study by Monash University researchers reveals that bees use a 'hot' drink to warm up on cold days and a 'cool' drink in warmer weather. The bees preferred feeding from artificial flowers with warmer nectar, which helped them maintain an optimal body temperature for flight.
A new study from North Carolina State University found large discrepancies in ADHD diagnosis rates based on small differences in children's birth dates. Children born shortly after the kindergarten eligibility cutoff date were 25% less likely to be diagnosed with ADHD, suggesting that younger children may be mistakenly diagnosed.
A recent study by University of Alberta research fellow Amy Speed-Andrews found that Iyengar yoga improved physical and mental health in breast cancer survivors. The 10-week program showed significant reductions in stress, anxiety, and depression, with participants experiencing improvements in quality of life and overall well-being.
A recent study by the University of Michigan Health System found that black patients are prescribed fewer pain medications than whites, while women receive weaker doses. The research highlights racial and gender gaps in pain care and suggests changes are needed to address these disparities starting in primary care.
Children as young as 3-4 years old use statistical information to infer the preferences of others. In experiments, they were more likely to give a toy to someone who had selected it from a container with a low proportion of that toy type. This ability is crucial for learning about others' desires and preferences.
Researchers estimate that harnessing 10% of Australia's near-shore wave energy could generate enough electricity to meet half of the country's present-day consumption. This could contribute significantly to Australia's goal of producing 45,000 gigawatt-hours/year of additional renewable energy by 2020.
Princeton researchers uncover ancient sponge-like creatures with fossilized shells dating to 650 million years ago, rewriting the timeline of life on Earth. The discovery provides direct evidence that animal life existed before and survived a severe 'snowball Earth' event.
Scientists have discovered an accomplice in breast cancer – a master control switch with the power to set off a cascade of reactions orchestrated by a cancer-causing gene named Wnt1. The executive molecule MTA1 is reported to trigger cancer-causing signals from Wnt1 in human breast cancer cells, leading to tumors.
Physicists have discovered evidence of natural nuclear accelerators at work in the Milky Way galaxy, based on an analysis of data from the world's largest cosmic ray detector. The researchers found that stellar explosions in our own galaxy can accelerate both protons and nuclei, explaining the origin of ultra-high-energy nuclei.
A Michigan State University economist found that nearly 20% of the 4.5 million children currently diagnosed with ADHD may have been misdiagnosed due to their age relative to classmates. The study suggests that teachers' perceptions of young children's behavior can lead to incorrect diagnoses and unnecessary medication.
Research published in the Journal of Physiology found that astronaut muscles deteriorate to that of an 80-year-old after just 180 days in space. The study highlights the need for effective exercise countermeasures to protect muscle and bone on long-duration space missions.
The discovery of primitive sponge-like creatures living in ocean reefs around 650 million years ago pushes back the clock on when animal life appeared on Earth. The fossils, found in South Australia, represent the earliest evidence of animal body forms in the current fossil record.
Researchers at Boston University and VA have discovered a new disease, CTEM, that mimics ALS in athletes with repeated head trauma. The disease is characterized by abnormal tau protein deposits and TDP-43 pathology, which are also found in sporadic ALS cases.
Scientists at Tohoku University have recorded data at a world-record density of 4 trillion bits per square inch using the ferroelectric data storage method. This density is eight times that of today's most advanced magnetic hard-disk drives.
Researchers at Iowa State University have discovered a special set of sugars that helps certain pathogens evade the body's natural defenses and vaccines. The finding may lead to new research for developing vaccines or cures for diseases like tuberculosis.
Researchers discover small RNAs regulate genes involved in chronic pain, offering a new avenue for developing drugs to treat debilitating conditions like arthritis and back pain. Small RNAs may serve as possible drug targets to restore normal pain thresholds.
A large, randomized controlled trial found that a surgically implanted antibiotic sponge did not reduce the rate of sternal wound infections after cardiac surgery. The study contradicts previous results and suggests ethnic and regional differences may have contributed to the differing outcomes.
A recent study conducted by researchers from the University of Chicago found that marriage and committed relationships significantly lower cortisol levels and increase testosterone production in response to psychological stress. The findings suggest that long-term monogamous relationships can have a dampening effect on stress hormones.
Researchers found that emodin from Chinese herbs can lower blood glucose and serum insulin levels in mice with diet-induced obesity. The herb's active compound effectively limits the effect of glucocorticoids, which contribute to insulin resistance.
Researchers have created the world's first frozen repository for Hawaiian coral, banking cells to preserve species diversity and potentially restore populations. The frozen material can be thawed decades or even centuries later to revive coral reefs threatened by climate change, pollution, and human impact.
Researchers estimate ITN coverage in 44 African countries between 2000 and 2008, with some countries scaling up coverage to over 60%. However, others, such as Nigeria, remain undercovered. The study suggests increased development assistance for health is related to improved ITN coverage.
A collaborative study examines a family with two rare genetic deletions, CNTNAP5 and DOCK4, which are associated with autism and reading difficulties. The research suggests that the CNTNAP5 deletion is linked to autism, while the DOCK4 deletion is co-segregated with reading difficulties.
The CLASS Act has the potential to transform long-term care financing in the US by introducing a voluntary, federally administered insurance program. This program would provide middle-class Americans with the choice to plan ahead for personal care and supportive service needs.
Researchers are developing a new vaccine technology using MHC tetramers to accelerate bovine vaccine creation, promising faster and more accurate development of vaccines for East Coast fever and foot-and-mouth disease. The goal is to provide basic science insights needed for better disease control in developing countries.
Researchers found that hospitalized patients with dysphagia averaged a 40% longer hospital stay than those without the condition. Dysphagia is severely underreported and can lead to complications such as aspiration pneumonia and increased end-of-life costs.
A recent study finds that workplace relationships after retirement are vital for maintaining social interaction and personal ties. Those who retired recently were more likely to keep work-related connections, highlighting the importance of networking throughout life.
A CSHL-led team found that increased IL-6 secretion can lead to decreased sensitivity to Tarceva, a targeted therapy for lung cancer. They also discovered that tumor cells with up-regulated TGF-β and increased IL-6 secretion were resistant to treatment independently of the EGFR pathway.
A recent study estimates that investigating allegations of scientific misconduct can cost up to $525,000 per case. The authors also found that annual reported cases in the US could exceed $110 million. By prioritizing prevention, academic institutions can reduce these substantial costs and promote a culture of integrity.
Researchers from the Antwerp Institute of Tropical Medicine found that targeted disease campaigns often displace basic healthcare services, leaving patients without access to curative care. Only a few health centers with experienced staff were able to integrate campaign work into their daily duties.
A study examines the impact of energy drink consumption on athletic performance and body composition, finding that caffeine is a key contributor to performance enhancement, while weight loss benefits are uncertain and may be linked to diminishing returns.
A study by Ryotaro Uemura found that people without a religious affiliation hold less favorable opinions about the US. In contrast, ethnic minority groups and first-generation US citizens do not necessarily exhibit significant differences in national attitudes.
A study by University of Wisconsin-Madison researchers found that traditional approaches to cancer education are ineffective for Hmong communities due to cultural differences. The team developed a new strategy based on community-participatory research, which led to a better understanding of the community's needs and perspectives.
The prevalence of hearing loss among US adolescents increased significantly, with 1 in 5 adolescents affected in 2005-2006. The majority of hearing loss was slight, and females were less likely to demonstrate any hearing loss.
Researchers at Georgia Tech Research Institute developed a system to measure high-energy laser beam power and spatial energy distribution. The reusable target board and beam diagnostic system enables simultaneous measurement of power and energy distribution, optimizing lasers for national security.
A study published in PLOS Medicine found that probabilistic models are as effective as physician reviews in establishing cause of death from verbal autopsy data. The models were more internally consistent and faster, with no differences in public health policy conclusions. This approach is recommended for incorporating death data into ...
Most hospitals surveyed have adopted hand-hygiene practices to prevent MRSA spread. The study found that nearly all hospitals review antimicrobial prescription orders to reduce bacterial resistance.
A new study explores the impact of alcohol intoxication on reasoning and problem-solving abilities. Researchers found that executive functions don't recover as quickly as subjective feelings of drunkenness, explaining why many individuals feel they can drive after drinking.
A Mediterranean diet high in antioxidants and omega-3 fatty acids has been shown to reduce the damaging effects of UV rays on the skin. Foods such as olive oil, fish, fruits and vegetables can provide essential nutrients to protect against skin cancer, while regular sunscreen applications and protective clothing are also crucial.
The Virginia Bioinformatics Institute's COPASI software package has been made open source, allowing global access and use. The new license agreement enables commercial users to freely use the software, while also enhancing its compatibility with other academic programs.
A study of 140 overweight children found that those with signs of poor blood sugar regulation had less bone mass, a measure of bone strength. Higher abdominal fat was linked to lower bone mass and more body fat overall was associated with higher bone mass.
The new atlas identifies areas with urgent need for mass treatment and predicts infection risk in data-lacking areas. The Global Atlas of Helminth Infections aims to improve sanitation and health education to control worm infections.
A new study by NewYork-Presbyterian Hospital/Columbia University Medical Center researchers found that the birth control pill works equally well in women with obesity and thinner women. The study's findings strengthen the message to patients that the pill will only work if it is taken every day.
A study of over 13,000 students found that only children were selected as friends by their peers just as often as those with siblings. The researchers suggest that children learn essential social skills through interactions in school and extracurricular activities.
A study published in Annals of Internal Medicine found that the University of Michigan's full disclosure program for medical errors resulted in a significant decrease in new claims, time to resolution, and liability costs. This improvement in transparency and compensation led to reduced malpractice costs and enhanced patient safety.
Researchers found that fields amended with poultry litter can accumulate significant levels of arsenic, which can then migrate into nearby streams and rivers. The study highlights the importance of controlling point sources of arsenic and suggests management practices to protect local regions from agricultural pollutants.
Researchers at Beth Israel Deaconess Medical Center discovered that the MDM2 oncogene is regulated by a complex signaling pathway involving enzymes CKI and beta-TRCP1. This finding suggests a 'dimmer switch' control mechanism, which could lead to new drug targets for killing tumors.
Researchers at Rice University are developing a genomic test that can quickly determine whether a disease outbreak is caused by a natural pathogen or one engineered in a lab. By studying how bacteria evolve in the lab, they hope to find common patterns that indicate domestication.